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The map label for this gene is talC

Identifier: 42521697

GI number: 42521697

Start: 43235

End: 43882

Strand: Direct

Name: talC

Synonym: Bd0049

Alternate gene names: 42521697

Gene position: 43235-43882 (Clockwise)

Preceding gene: 42521696

Following gene: 42521698

Centisome position: 1.14

GC content: 46.91

Gene sequence:

>648_bases
ATGAAGTTTTTCATCGATACAGCAGAAATTGAAGAAATCAGACAAGCCAATCTTCGTGGTTGGGTTGACGGTGTTACCAC
CAACCCTTCTTTGATCGCAAAAAGCGGCAAGGACTTCCACACCGTGATCAAAGAGATCTGCAAAGAGATCACAGGTCCAG
TTTCTGCGGAAGTGATCAGCCTGCAACACGAAGAAATGGTTCGTGAAGGTAAAGAGCTGGCGAAACTGGCTTCCAACGTT
GTGGTGAAAATCCCAATGTGTGAAGACGGCATGATCGCCGTAAAGAAATTGAAATCAGAAGGCATCAAGACCAACGTCAC
ACTGGTGTTCTCTCCAATGCAGGCATTGCTTGCGGCTAAAGCCGGCGCGACGATGGTATCCCCGTTCGTGGGTCGTCTTG
ACGACATTGGTGTTGAAGGTATGCAGATGGTTGATCAGGTTATCCAGATGTACCGCAACTATGACTTCGAGACTGAAGTA
TTGGTAGCCAGTGTAAGAAGCCCGATGCATATCCAACTTGCAGCTGAAATGGGCGCGGACATCGCGACTATTCCGTTTAA
AGTAATGCAATCCATGACTCACCATCCGTTAACTGACAAAGGTATCAAGATGTTCATGGATGACTGGAACAAGGCTCAGA
AGAAATAA

Upstream 100 bases:

>100_bases
GAGTTCCATATTCAGGGTAAAAGCCTGGTTGATTTTTAATCCTGGAAAACGTACAAATTGAGGGTATCCAAAAATCACGT
TTCCAGACTCGGGAGTCCCC

Downstream 100 bases:

>100_bases
TGATGAAGACCTTCGTCTGGGTATTCCTTCTTGCATCGACGCTTTTTTTTGCTGGTTGTCGCACCGGTGGGGTGATCTTG
CGTGAAACCCCGCTCAACCT

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MKFFIDTAEIEEIRQANLRGWVDGVTTNPSLIAKSGKDFHTVIKEICKEITGPVSAEVISLQHEEMVREGKELAKLASNV
VVKIPMCEDGMIAVKKLKSEGIKTNVTLVFSPMQALLAAKAGATMVSPFVGRLDDIGVEGMQMVDQVIQMYRNYDFETEV
LVASVRSPMHIQLAAEMGADIATIPFKVMQSMTHHPLTDKGIKMFMDDWNKAQKK

Sequences:

>Translated_215_residues
MKFFIDTAEIEEIRQANLRGWVDGVTTNPSLIAKSGKDFHTVIKEICKEITGPVSAEVISLQHEEMVREGKELAKLASNV
VVKIPMCEDGMIAVKKLKSEGIKTNVTLVFSPMQALLAAKAGATMVSPFVGRLDDIGVEGMQMVDQVIQMYRNYDFETEV
LVASVRSPMHIQLAAEMGADIATIPFKVMQSMTHHPLTDKGIKMFMDDWNKAQKK
>Mature_215_residues
MKFFIDTAEIEEIRQANLRGWVDGVTTNPSLIAKSGKDFHTVIKEICKEITGPVSAEVISLQHEEMVREGKELAKLASNV
VVKIPMCEDGMIAVKKLKSEGIKTNVTLVFSPMQALLAAKAGATMVSPFVGRLDDIGVEGMQMVDQVIQMYRNYDFETEV
LVASVRSPMHIQLAAEMGADIATIPFKVMQSMTHHPLTDKGIKMFMDDWNKAQKK

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=169, Percent_Identity=32.5443786982249, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI87081788, Length=214, Percent_Identity=32.7102803738318, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790382, Length=214, Percent_Identity=36.4485981308411, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788807, Length=196, Percent_Identity=30.1020408163265, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786189, Length=174, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25153750, Length=173, Percent_Identity=30.635838150289, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321480, Length=222, Percent_Identity=28.8288288288288, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45549185, Length=175, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_BDEBA (Q6MRM6)

Other databases:

- EMBL:   BX842646
- RefSeq:   NP_967077.1
- HSSP:   Q9WYD1
- ProteinModelPortal:   Q6MRM6
- SMR:   Q6MRM6
- GeneID:   2733556
- GenomeReviews:   BX842601_GR
- KEGG:   bba:Bd0049
- NMPDR:   fig|264462.1.peg.47
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- PhylomeDB:   Q6MRM6
- ProtClustDB:   PRK01362
- BioCyc:   BBAC264462:BD0049-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23857; Mature: 23857

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
7.0 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
7.0 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFIDTAEIEEIRQANLRGWVDGVTTNPSLIAKSGKDFHTVIKEICKEITGPVSAEVIS
CCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHH
LQHEEMVREGKELAKLASNVVVKIPMCEDGMIAVKKLKSEGIKTNVTLVFSPMQALLAAK
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHH
AGATMVSPFVGRLDDIGVEGMQMVDQVIQMYRNYDFETEVLVASVRSPMHIQLAAEMGAD
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEHHHHCCC
IATIPFKVMQSMTHHPLTDKGIKMFMDDWNKAQKK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFFIDTAEIEEIRQANLRGWVDGVTTNPSLIAKSGKDFHTVIKEICKEITGPVSAEVIS
CCEEECHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHH
LQHEEMVREGKELAKLASNVVVKIPMCEDGMIAVKKLKSEGIKTNVTLVFSPMQALLAAK
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEHHHHHHHHHH
AGATMVSPFVGRLDDIGVEGMQMVDQVIQMYRNYDFETEVLVASVRSPMHIQLAAEMGAD
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCEEEEHHHHCCC
IATIPFKVMQSMTHHPLTDKGIKMFMDDWNKAQKK
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA