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The map label for this gene is sigM

Identifier: 41410435

GI number: 41410435

Start: 4818485

End: 4819072

Strand: Direct

Name: sigM

Synonym: MAP4337

Alternate gene names: 41410435

Gene position: 4818485-4819072 (Clockwise)

Preceding gene: 41410434

Following gene: 41410436

Centisome position: 99.77

GC content: 73.64

Gene sequence:

>588_bases
GTGGGCTTCGGAAGAAACGGCAACGGTGACCGCAGCGACGCCGAGCTGCTGGCAGCCCACGTGGCCGGCGACCGGTACGC
CTTCGGCGAGCTGTTCGTCCGGCATCAGCGCCACCTGCACCGGCTGGCCCGGCTCACGACGCGCAGCCCCGAGGACGCCG
AAGACGCGCTGCAGGACGCCATGCTCTCGGCACACCGCGGCGCGGGCGCGTTCCGGCATGACGCGGCCGTCGGCAGCTGG
CTGCACCGCATCGTGGTGAACGCCTGCCTGGACCGGCTGCGCCGCACCAAGGCCCACCCGACGGTCCCGCTGGAAGACAT
CTATCCGGTCGCCGATCGCACGGCCCAGGTGGAGACGACGCTGGCGGTGCAGCGCGCCCTGATGCGGCTGCCGGTCGAAC
AACGCGCGGCGATCGTCGCCGTCGACATGCAGGGCTATTCGGTGGCCGACACCGCGCGGCTGCTCGGCGTTGCCGAGGGC
ACCGTCAAGAGCCGGTGCGCCCGCGCCCGGGTGCGGCTCGCCGAACTGCTGGGCTATCTCGATGCCGGGGCCCACGCCGC
TGCCGAGGGCGCCGCCGGCCAGGCCTGA

Upstream 100 bases:

>100_bases
ACGGTCCAGGCCGCGTCCTGAATCCCGGCGCGTCGCAAGCACTCACATGAGCGCCGGCGAGTGAAGTGCCGCGGGATACC
CGATTGGTTACTGTCCGGCC

Downstream 100 bases:

>100_bases
CGGCGGCCCCGCACTGGCCGTCCGTGGCGATCGCTGCGGCCATGACGGACACTGGGTCCGATGGCTACAGCGGGCAACGA
CGCGGCGGATCACCGCAACG

Product: RNA polymerase sigma factor SigM

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MGFGRNGNGDRSDAELLAAHVAGDRYAFGELFVRHQRHLHRLARLTTRSPEDAEDALQDAMLSAHRGAGAFRHDAAVGSW
LHRIVVNACLDRLRRTKAHPTVPLEDIYPVADRTAQVETTLAVQRALMRLPVEQRAAIVAVDMQGYSVADTARLLGVAEG
TVKSRCARARVRLAELLGYLDAGAHAAAEGAAGQA

Sequences:

>Translated_195_residues
MGFGRNGNGDRSDAELLAAHVAGDRYAFGELFVRHQRHLHRLARLTTRSPEDAEDALQDAMLSAHRGAGAFRHDAAVGSW
LHRIVVNACLDRLRRTKAHPTVPLEDIYPVADRTAQVETTLAVQRALMRLPVEQRAAIVAVDMQGYSVADTARLLGVAEG
TVKSRCARARVRLAELLGYLDAGAHAAAEGAAGQA
>Mature_194_residues
GFGRNGNGDRSDAELLAAHVAGDRYAFGELFVRHQRHLHRLARLTTRSPEDAEDALQDAMLSAHRGAGAFRHDAAVGSWL
HRIVVNACLDRLRRTKAHPTVPLEDIYPVADRTAQVETTLAVQRALMRLPVEQRAAIVAVDMQGYSVADTARLLGVAEGT
VKSRCARARVRLAELLGYLDAGAHAAAEGAAGQA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=176, Percent_Identity=31.25, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014293
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21049; Mature: 20918

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFGRNGNGDRSDAELLAAHVAGDRYAFGELFVRHQRHLHRLARLTTRSPEDAEDALQDA
CCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
MLSAHRGAGAFRHDAAVGSWLHRIVVNACLDRLRRTKAHPTVPLEDIYPVADRTAQVETT
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHCCHHHHHHH
LAVQRALMRLPVEQRAAIVAVDMQGYSVADTARLLGVAEGTVKSRCARARVRLAELLGYL
HHHHHHHHHCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAGAHAAAEGAAGQA
HCCCHHHHCCCCCCC
>Mature Secondary Structure 
GFGRNGNGDRSDAELLAAHVAGDRYAFGELFVRHQRHLHRLARLTTRSPEDAEDALQDA
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
MLSAHRGAGAFRHDAAVGSWLHRIVVNACLDRLRRTKAHPTVPLEDIYPVADRTAQVETT
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHCCHHHHHHH
LAVQRALMRLPVEQRAAIVAVDMQGYSVADTARLLGVAEGTVKSRCARARVRLAELLGYL
HHHHHHHHHCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAGAHAAAEGAAGQA
HCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]