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The map label for this gene is fabG [H]

Identifier: 41410391

GI number: 41410391

Start: 4760122

End: 4760883

Strand: Direct

Name: fabG [H]

Synonym: MAP4293

Alternate gene names: 41410391

Gene position: 4760122-4760883 (Clockwise)

Preceding gene: 41410390

Following gene: 41410392

Centisome position: 98.56

GC content: 72.31

Gene sequence:

>762_bases
GTGACAGACGAGCTGCGGGGCCGGCGGATCCTGGTGACCGGCGCCGCCACCGGTATCGGCGCGGCCGCCGTCAGCGTCCT
CACCGACGCGGGCGCCGACGTCGTCGCGACCTATCACACGACGCCACCGCCGCCGGATCTGACGGCGCACTGGTTGCAGT
GCGACGCGCGCGACGCCGACGCCGTCTCGGCCCTGGTCCACCGGGCCGCCGAGCACCTGGGTGGGCTCGACGTGCTGGTG
CACGCCGCGGGGCTGTGGCAGCCGGGGATACCCGGCTGCATCGGCGCCGACGACATCTCGTTTCTGTTGGACACCAACGT
CAAGGCGACCATCCTGACCAATCAAGCCGCCCACGCCGCCATGAAGGCCCAAGACCCCAAGGGCGGCCGGATCATCAACT
TCGGCTCCTCGGAAGCCGTTATGGGCAGCCCGATTTCGGCCGTCTACGCCGCGACCAAGGGCGCGGTGCAGGCCTGGACC
CGCTCGGCGGCCAAGGCCTGGGCCGCCGACCACGTCACCGTCAACGCCCTTGCCCCGGCGGTGCAGACGCCGGGCGCCGA
CCGGCTCCGCGCGTTCCTCGGCCCGGACGCCGCCGCGCTGATCGACCAGCAGATGCAGATGATGATCCCGCTGGGTGGCG
CGCTGGGCGAGCCGGCCCGCGACCTCGGGCCGATGCTGGTGTTCCTGGCCGGGTCCGGGTCGGGCTTCATCACCGGACAA
CTGCTGGCCGTCGACGGCGGCCTGATGATGGTGGGCGCATAG

Upstream 100 bases:

>100_bases
GTCGACGGTCGCGGTGCGCACCTGAGGCATTGCGGTTCACGCGCGTAACCCCACGGCGAAATCTCGTTGGGATTATCGCC
GTGGGGTTACGCTCGCGGGC

Downstream 100 bases:

>100_bases
CCCGCCCGCCCGCCGCCGCTCGGCCGCTACTATAAGACGGACCGTCTCGTCTCGCAGGGCAGGCATAGTGAAGGTGGGGC
CGACCGATGGCTGAGGACAC

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTDELRGRRILVTGAATGIGAAAVSVLTDAGADVVATYHTTPPPPDLTAHWLQCDARDADAVSALVHRAAEHLGGLDVLV
HAAGLWQPGIPGCIGADDISFLLDTNVKATILTNQAAHAAMKAQDPKGGRIINFGSSEAVMGSPISAVYAATKGAVQAWT
RSAAKAWAADHVTVNALAPAVQTPGADRLRAFLGPDAAALIDQQMQMMIPLGGALGEPARDLGPMLVFLAGSGSGFITGQ
LLAVDGGLMMVGA

Sequences:

>Translated_253_residues
MTDELRGRRILVTGAATGIGAAAVSVLTDAGADVVATYHTTPPPPDLTAHWLQCDARDADAVSALVHRAAEHLGGLDVLV
HAAGLWQPGIPGCIGADDISFLLDTNVKATILTNQAAHAAMKAQDPKGGRIINFGSSEAVMGSPISAVYAATKGAVQAWT
RSAAKAWAADHVTVNALAPAVQTPGADRLRAFLGPDAAALIDQQMQMMIPLGGALGEPARDLGPMLVFLAGSGSGFITGQ
LLAVDGGLMMVGA
>Mature_252_residues
TDELRGRRILVTGAATGIGAAAVSVLTDAGADVVATYHTTPPPPDLTAHWLQCDARDADAVSALVHRAAEHLGGLDVLVH
AAGLWQPGIPGCIGADDISFLLDTNVKATILTNQAAHAAMKAQDPKGGRIINFGSSEAVMGSPISAVYAATKGAVQAWTR
SAAKAWAADHVTVNALAPAVQTPGADRLRAFLGPDAAALIDQQMQMMIPLGGALGEPARDLGPMLVFLAGSGSGFITGQL
LAVDGGLMMVGA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=29.9595141700405, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=29.1044776119403, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=26.9230769230769, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI59889578, Length=202, Percent_Identity=35.6435643564356, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=31.6, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI109715829, Length=221, Percent_Identity=27.1493212669683, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1789208, Length=253, Percent_Identity=33.596837944664, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=30.3149606299213, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787335, Length=255, Percent_Identity=28.2352941176471, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1789378, Length=261, Percent_Identity=31.4176245210728, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=27.5862068965517, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI2367365, Length=253, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=28.0155642023346, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787891, Length=242, Percent_Identity=27.6859504132231, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=262, Percent_Identity=29.7709923664122, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=251, Percent_Identity=26.2948207171315, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=28.2608695652174, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=270, Percent_Identity=27.037037037037, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=27.4074074074074, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=28.4974093264249, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=29.6442687747036, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=26.3565891472868, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=28.0632411067194, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=27.4509803921569, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007234, Length=193, Percent_Identity=27.979274611399, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116007232, Length=164, Percent_Identity=29.8780487804878, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25686; Mature: 25554

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDELRGRRILVTGAATGIGAAAVSVLTDAGADVVATYHTTPPPPDLTAHWLQCDARDAD
CCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEHEEEECCCCHH
AVSALVHRAAEHLGGLDVLVHAAGLWQPGIPGCIGADDISFLLDTNVKATILTNQAAHAA
HHHHHHHHHHHHHCCHHEEHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEECHHHHHH
MKAQDPKGGRIINFGSSEAVMGSPISAVYAATKGAVQAWTRSAAKAWAADHVTVNALAPA
HHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCH
VQTPGADRLRAFLGPDAAALIDQQMQMMIPLGGALGEPARDLGPMLVFLAGSGSGFITGQ
HCCCCHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCHHHCCCEEEEEECCCCCEEEEE
LLAVDGGLMMVGA
EEEECCCEEEEEC
>Mature Secondary Structure 
TDELRGRRILVTGAATGIGAAAVSVLTDAGADVVATYHTTPPPPDLTAHWLQCDARDAD
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEHEEEECCCCHH
AVSALVHRAAEHLGGLDVLVHAAGLWQPGIPGCIGADDISFLLDTNVKATILTNQAAHAA
HHHHHHHHHHHHHCCHHEEHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEECHHHHHH
MKAQDPKGGRIINFGSSEAVMGSPISAVYAATKGAVQAWTRSAAKAWAADHVTVNALAPA
HHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCH
VQTPGADRLRAFLGPDAAALIDQQMQMMIPLGGALGEPARDLGPMLVFLAGSGSGFITGQ
HCCCCHHHHHHHHCCCHHHHHHHHHHHHEECCCCCCCCHHHCCCEEEEEECCCCCEEEEE
LLAVDGGLMMVGA
EEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]