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The map label for this gene is gcp

Identifier: 41410361

GI number: 41410361

Start: 4731716

End: 4732741

Strand: Direct

Name: gcp

Synonym: MAP4263

Alternate gene names: 41410361

Gene position: 4731716-4732741 (Clockwise)

Preceding gene: 41410360

Following gene: 41410362

Centisome position: 97.97

GC content: 74.37

Gene sequence:

>1026_bases
GTGACGACCATCCTGGCGATCGAAACCTCTTGCGACGAAACGGGAGTCGGCATCGCGCGGCTGGACGCCGACGGCGCGGT
GACCCTGCTGGCCGACGAGGTCGCCTCCAGCGTCGACGAGCACGTGCGGTTCGGCGGCGTGGTGCCCGAGATCGCGTCGC
GCGCACACCTGGAGGCCCTGGGGCCCACCATGCGCCGCGCCCTGTCCGCCGCCGGCGTGACCAAACCCGACGTCGTCGCG
GCCACCATCGGGCCCGGGCTGGCCGGTGCCCTGCTGGTGGGAGTCGCTGCGGCCAAAGCGTATTCGGCGGCCTGGGGGGT
GCCGTTCTACGCCGTCAACCACCTGGGCGGGCACCTGGCCGCCGACGTCTACCAGCACGGGCCGCTGCCCGAGTGCGTCG
CGCTGCTGGTCTCCGGCGGCCACACCCACCTGCTGCAGGTGCGCTCGCTCGGCGACCCGATCGTCGAGCTGGGCAGCACC
GTCGACGACGCCGCGGGCGAGGCCTACGACAAGGTGGCGCGGCTGCTGGGGCTGGGCTACCCGGGCGGCCGGGTGCTCGA
CGAGCTGGCCCGCACCGGCGACCGGGAGGCGATCGTGTTCCCGCGCGGCATGACCGGCCCGCGTGACGCCCCGTACGCGT
TCAGTTTCTCCGGGCTCAAGACGGCCGTGGCGCGGTACCTGGAAAGCCACCCGGACGCGGTGAACGCCGACGTCGCGGCC
GGCTTCCAGGAGGCCGTCGCCGACGTACTGACCCGCAAGGCGGTGCGCGCGGCCACCGACCTCGGCGTCACCACCCTGCT
GATCGCGGGGGGAGTGGCCGCCAACTCGCGGCTGCGCGAGCTGGCCGAGCAGCGCTGCGCGGCGGCCGGGCTGACGCTGC
GCATACCCCGGCCGGGGCTGTGCACCGACAACGGGGCGATGATCGCGTCGTTCGCCGCGCATCTGGTGGCCGCCGGGGCG
CCGCCGTCGCCGTTGGACGTGCCCACCGATCCGGGCCTGCCGGTGGTGAAAGCGCAGGTCAGCTGA

Upstream 100 bases:

>100_bases
GGTTGTATCGCAGCGTCGGGTTCGAGCAGATCGGCCTGCGCCGGCGCTATTACCGCATCAGCGGCGCCGACGCCTACACC
ATGCGCAGAAAGGCCCGGCA

Downstream 100 bases:

>100_bases
TCGCCGACGGCGAACACACGAGAAGCAGCGGAGTGCCCTTGAGTGCTAGCACTCGCATGTATAGAGTGCTAGGTGGCAAT
CGACCAAGCCCGGTGTCGGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPTMRRALSAAGVTKPDVVA
ATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYQHGPLPECVALLVSGGHTHLLQVRSLGDPIVELGST
VDDAAGEAYDKVARLLGLGYPGGRVLDELARTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESHPDAVNADVAA
GFQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCAAAGLTLRIPRPGLCTDNGAMIASFAAHLVAAGA
PPSPLDVPTDPGLPVVKAQVS

Sequences:

>Translated_341_residues
MTTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPTMRRALSAAGVTKPDVVA
ATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYQHGPLPECVALLVSGGHTHLLQVRSLGDPIVELGST
VDDAAGEAYDKVARLLGLGYPGGRVLDELARTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESHPDAVNADVAA
GFQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCAAAGLTLRIPRPGLCTDNGAMIASFAAHLVAAGA
PPSPLDVPTDPGLPVVKAQVS
>Mature_340_residues
TTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVRFGGVVPEIASRAHLEALGPTMRRALSAAGVTKPDVVAA
TIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLAADVYQHGPLPECVALLVSGGHTHLLQVRSLGDPIVELGSTV
DDAAGEAYDKVARLLGLGYPGGRVLDELARTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESHPDAVNADVAAG
FQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCAAAGLTLRIPRPGLCTDNGAMIASFAAHLVAAGAP
PSPLDVPTDPGLPVVKAQVS

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=334, Percent_Identity=33.2335329341317, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=31.0975609756098, Blast_Score=104, Evalue=1e-22,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=45.906432748538, Blast_Score=236, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71995670, Length=326, Percent_Identity=31.2883435582822, Blast_Score=111, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17557464, Length=334, Percent_Identity=30.2395209580838, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320099, Length=358, Percent_Identity=29.0502793296089, Blast_Score=121, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322891, Length=339, Percent_Identity=27.4336283185841, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI20129063, Length=345, Percent_Identity=32.7536231884058, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21357207, Length=338, Percent_Identity=30.1775147928994, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_MYCA1 (A0QKR4)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_883502.1
- ProteinModelPortal:   A0QKR4
- SMR:   A0QKR4
- STRING:   A0QKR4
- EnsemblBacteria:   EBMYCT00000011505
- GeneID:   4525654
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_4367
- TIGR:   MAV_4367
- eggNOG:   COG0533
- GeneTree:   EBGT00050000017447
- HOGENOM:   HBG304663
- OMA:   PLYGVNH
- ProtClustDB:   PRK09604
- BioCyc:   MAVI243243:MAV_4367-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 34723; Mature: 34592

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVRFGGVVPEIASRAHLEAL
CCEEEEEECCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GPTMRRALSAAGVTKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLA
CHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHH
ADVYQHGPLPECVALLVSGGHTHLLQVRSLGDPIVELGSTVDDAAGEAYDKVARLLGLGY
HHHHHCCCHHHHHHHHHCCCCHHEEEHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCC
PGGRVLDELARTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESHPDAVNADVAA
CCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHH
GFQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCAAAGLTLRIPRPGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCC
CTDNGAMIASFAAHLVAAGAPPSPLDVPTDPGLPVVKAQVS
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TTILAIETSCDETGVGIARLDADGAVTLLADEVASSVDEHVRFGGVVPEIASRAHLEAL
CEEEEEECCCCCCCCCEEEECCCCCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GPTMRRALSAAGVTKPDVVAATIGPGLAGALLVGVAAAKAYSAAWGVPFYAVNHLGGHLA
CHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHH
ADVYQHGPLPECVALLVSGGHTHLLQVRSLGDPIVELGSTVDDAAGEAYDKVARLLGLGY
HHHHHCCCHHHHHHHHHCCCCHHEEEHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCC
PGGRVLDELARTGDREAIVFPRGMTGPRDAPYAFSFSGLKTAVARYLESHPDAVNADVAA
CCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCCCCHHHHH
GFQEAVADVLTRKAVRAATDLGVTTLLIAGGVAANSRLRELAEQRCAAAGLTLRIPRPGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEECCCCCC
CTDNGAMIASFAAHLVAAGAPPSPLDVPTDPGLPVVKAQVS
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA