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The map label for this gene is secY

Identifier: 41410296

GI number: 41410296

Start: 4668000

End: 4669325

Strand: Direct

Name: secY

Synonym: MAP4198

Alternate gene names: 41410296

Gene position: 4668000-4669325 (Clockwise)

Preceding gene: 41410294

Following gene: 41410297

Centisome position: 96.65

GC content: 64.25

Gene sequence:

>1326_bases
TTGCTTTCGGCTTTCATCTCATCGCTGCGGACAGTCGACCTGAGACGGAAGATCCTCTTCACGCTGGGCATCGTCGTCCT
GTACCGGGTCGGGGCCGCGTTGCCGTCCCCGGGCGTCAACTACCCCAACGTCCAGCAGTGCATCAAGGAAGCCAGCGGCG
GCGCGGCCGGGCAGATCTACTCGCTGATCAACCTGTTCTCCGGCGGCGCGTTGCTCAAACTCACCGTGTTCGCCGTCGGG
GTGATGCCCTACATCACCGCCAGCATCATCGTGCAGCTGCTCACCGTCGTCATCCCGCGCTTCGAGGAACTGCGCAAGGA
AGGTCAGTCCGGTCAGGCCAAGATGACGCAGTACACCCGCTACCTGGCCATCGCGCTGGCCATCCTGCAGGCCACCAGCA
TCGTGGCGCTGGCCGCCAACGGCGGGCTGCTGCAGGGCTGCTCACTGGACATCATCGCCGACCAATCCATCTTCACCCTC
GTCGTCATCGTGCTGGTGATGACGGCCGGCGCGGCGCTGGTGATGTGGATGGGCGAGCTGATCACCGAGCGCGGCATCGG
CAACGGCATGTCCCTGCTGATCTTCGTCGGTATCGCGGCGCGCATCCCCGCCGAGGGCAAGACCATCCTGGACAGCCGCG
GCGGCATGATCTTCGCCGCCGTGCTGGTGGCCGCGCTGATCATCATCGTCGGCGTGGTGTTCGTCGAACAGGGGCAGCGC
CGCATCCCGGTGCAGTACGCCAAGCGGATGGTGGGCCGGCGCATGTACGGCGGCACCTCGACGTACCTGCCGCTCAAGGT
CAACCAGGCCGGCGTCATCCCGGTGATCTTCGCGTCCTCGCTGATCTACATCCCGCACCTGATCACCCAGCTGATCCGCA
GCGGCAGCGGCGGCGTCGGCAACAGCTGGTGGGACAAGTTCGTCGGCAGCTACCTGTCCGACCCCAGCGACCCGGTCTAC
ATCGGCATCTACTTCGGGCTGATCATCTTCTTCACGTACTTCTACGTGTCCATCACGTTCAACCCCGACGAGCGCGCCGA
CGAGATGAAGAAGTTCGGCGGCTTCATCCCCGGCATCCGGCCGGGCAAGCCCACCGCGGATTACCTGCGTTACGTGCTGA
GCCGGATCACCTTGCCCGGCTCCATCTACCTGGGTGCGATCTCGGTGCTGCCCAACCTGTTCCTGCAGATCGGCAACGGC
GGGGCGGTGCAGAACCTGCCGTTCGGCGGTACCGCGGTTTTGATCATGATCGGCGTGGGCTTGGATACGGTCAAGCAGAT
CGAGAGTCAGCTCATGCAGCGCAACTATGAAGGGTTCCTCAAGTGA

Upstream 100 bases:

>100_bases
GTACACGGTTTGACGCGCTGTAATTGAGTCGGGCCGTACGTCCTGGCCTGCGGGTGTTGGGCGCGTGATGCAGGAAATCC
CGGCTGCGCAGGAGGAAGAG

Downstream 100 bases:

>100_bases
GAGTCGTTTTGCTGGGGCCGCCGGGAGCGGGCAAGGGGACGCAGGCCCAGAAGCTCTCCGAGAAGCTCGGGATCCCGCAG
ATCTCCACCGGTGAGCTGTT

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MLSAFISSLRTVDLRRKILFTLGIVVLYRVGAALPSPGVNYPNVQQCIKEASGGAAGQIYSLINLFSGGALLKLTVFAVG
VMPYITASIIVQLLTVVIPRFEELRKEGQSGQAKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTL
VVIVLVMTAGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKTILDSRGGMIFAAVLVAALIIIVGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGGVGNSWWDKFVGSYLSDPSDPVY
IGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGSIYLGAISVLPNLFLQIGNG
GAVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Sequences:

>Translated_441_residues
MLSAFISSLRTVDLRRKILFTLGIVVLYRVGAALPSPGVNYPNVQQCIKEASGGAAGQIYSLINLFSGGALLKLTVFAVG
VMPYITASIIVQLLTVVIPRFEELRKEGQSGQAKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTL
VVIVLVMTAGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKTILDSRGGMIFAAVLVAALIIIVGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGGVGNSWWDKFVGSYLSDPSDPVY
IGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGSIYLGAISVLPNLFLQIGNG
GAVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK
>Mature_441_residues
MLSAFISSLRTVDLRRKILFTLGIVVLYRVGAALPSPGVNYPNVQQCIKEASGGAAGQIYSLINLFSGGALLKLTVFAVG
VMPYITASIIVQLLTVVIPRFEELRKEGQSGQAKMTQYTRYLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTL
VVIVLVMTAGAALVMWMGELITERGIGNGMSLLIFVGIAARIPAEGKTILDSRGGMIFAAVLVAALIIIVGVVFVEQGQR
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGGVGNSWWDKFVGSYLSDPSDPVY
IGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIRPGKPTADYLRYVLSRITLPGSIYLGAISVLPNLFLQIGNG
GAVQNLPFGGTAVLIMIGVGLDTVKQIESQLMQRNYEGFLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=437, Percent_Identity=42.79176201373, Blast_Score=297, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 47512; Mature: 47512

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSAFISSLRTVDLRRKILFTLGIVVLYRVGAALPSPGVNYPNVQQCIKEASGGAAGQIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
SLINLFSGGALLKLTVFAVGVMPYITASIIVQLLTVVIPRFEELRKEGQSGQAKMTQYTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
YLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTLVVIVLVMTAGAALVMWMGEL
HHHHHHHHHHHHHHEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ITERGIGNGMSLLIFVGIAARIPAEGKTILDSRGGMIFAAVLVAALIIIVGVVFVEQGQR
HHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGGVG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSWWDKFVGSYLSDPSDPVYIGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIR
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCC
PGKPTADYLRYVLSRITLPGSIYLGAISVLPNLFLQIGNGGAVQNLPFGGTAVLIMIGVG
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEHEECCC
LDTVKQIESQLMQRNYEGFLK
HHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MLSAFISSLRTVDLRRKILFTLGIVVLYRVGAALPSPGVNYPNVQQCIKEASGGAAGQIY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHH
SLINLFSGGALLKLTVFAVGVMPYITASIIVQLLTVVIPRFEELRKEGQSGQAKMTQYTR
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
YLAIALAILQATSIVALAANGGLLQGCSLDIIADQSIFTLVVIVLVMTAGAALVMWMGEL
HHHHHHHHHHHHHHEEEECCCCEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
ITERGIGNGMSLLIFVGIAARIPAEGKTILDSRGGMIFAAVLVAALIIIVGVVFVEQGQR
HHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
RIPVQYAKRMVGRRMYGGTSTYLPLKVNQAGVIPVIFASSLIYIPHLITQLIRSGSGGVG
CCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NSWWDKFVGSYLSDPSDPVYIGIYFGLIIFFTYFYVSITFNPDERADEMKKFGGFIPGIR
HHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHCCCCCCCC
PGKPTADYLRYVLSRITLPGSIYLGAISVLPNLFLQIGNGGAVQNLPFGGTAVLIMIGVG
CCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCEEEHEECCC
LDTVKQIESQLMQRNYEGFLK
HHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9350347; 12788972 [H]