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The map label for this gene is 41410226

Identifier: 41410226

GI number: 41410226

Start: 4600145

End: 4601596

Strand: Direct

Name: 41410226

Synonym: MAP4128

Alternate gene names: NA

Gene position: 4600145-4601596 (Clockwise)

Preceding gene: 41410224

Following gene: 41410227

Centisome position: 95.25

GC content: 71.49

Gene sequence:

>1452_bases
GTGCGCGCCGAAGTCACCGCGTTCGACCTGCCCGTCACCGGACGCATTCCCGACCACCTCGACGGGCGCTACCTGCGCAA
CGGCCCCAACCCGGTCGCCGAGGTCGACCCGGCGACCTACCACTGGTTCAGCGGCGACGGGATGGTCCACGGCGTGGCGC
TGCGCGACGGGCGGGCCCGCTGGTATCGCAACCGCTGGGTGCGCACCGCGCACGTGTGTGCCGCGCTCGGCGAGCCCGCG
CCCGGCGGGCTGGACCCGCGCGCCGGAATGCTGTCCGTCGGACCCAACACCAACGTGCTCGGCCACGCCGGGCAGACGCT
GGCCCTGGTCGAAGGGGGCGGCGCCAACTACCGGCTCACCGAGGACCTGGACACCGTCGGCACCTGCGACTTCGACGGAA
CCCTGTTCGGCGGCTACACCGCCCACCCGCACCGCGACCCCCGTACCGGCGAATTGCACGCCGTCTCCTACTCGTTCGGG
CGGGGGCGCCGCGTGCAGTACTCGGTGATCGACACCGCCGGCCGCGCGCGGCGCACCGTCGACATCGAGGTGAGCGGGTC
GCCGATGATGCACGACTTCTCGCTCACCGACGAGTACGTGGTGATCTACGACCTGCCCGTGACGTTCGACCCCGTCCAGG
TGATGCCGGCCGACGTGCCGCGCTGGCTGAGCGCACCGGCGCGGCTGGTCGTGCAGTCGCTGCTCGGGCGGGTGCAGCTG
CCCGGCCCGATGGCCACGGCGATGAACCGCAATCGGCAGCCGCTGCACCGGATGCCCTACCGGTGGAACGACGCCTACCC
GGCGCGGCTGGGCGTCATGCCCCGCGACGGCGGTAACGACGAGGTTCGGTGGTTCGACATCGAGCCCTGCTACGTCTACC
ACCCGCTCAACGCCTACTCCGAAATACGTGACGGCGCAAAGGTTTTGGTGCTCGACGTGGTGCGCTACTCGCGGATGTTC
GACCGCGACCTGCGCGGTCCCGGCGACACCCGCCCGACGCTGGACCGCTGGACCGTCAACCTGACGACCGGGGCGGTCGG
CAGCGAGCTGCGCGACGACCGCTCGCAGGAGTTCCCCCGGATCAACGAGGCCCTGCTGGGCCGGCGGCACCGCTTCGGCT
ACACCGTCGGCACCGACGGCGGCTACCCGTCCGACGGCGCCTCGGAGATGTCCACCGGCCTGTACAAGCACGACTACGCC
ACCGGCTCGCGCCGGGTCGCGCCGCTGGACCCCGACCTTTTGATCGGCGAGATGTGCTTCGTGCCCAACCCGGCCGGCGG
CCAAGACGGCGCGGAGGACGACGGCATCCTGATGGGCTTCGGCTATCACCGCGGCCGCGACGAAGGCCAGCTGGTGTTGC
TGGACGCCCAGAGTCTCGAGCAGGTGGCGACCGTGCACCTGCCGCAGCGGGTCCCGATGGGCTTCCACGGCAACTGGGTG
CCCGCTGGCTAA

Upstream 100 bases:

>100_bases
TACCGTCGCAATAACAGCGTAATATCAATGTTATAGGAGTCGGGCATGACCTCCACGCGCACCGTCGCCAATCCCCTATC
TGGACGGCTTCCTGGCGCCG

Downstream 100 bases:

>100_bases
CACGTGCGTCAAATAAGTTGTGCCGCGCGCGGTTCCGGGTGATCTCGGGACGGCCAAATTTGCACGGCGGTGCCGCGCAA
CCCTGATGCCGTGTGGCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MRAEVTAFDLPVTGRIPDHLDGRYLRNGPNPVAEVDPATYHWFSGDGMVHGVALRDGRARWYRNRWVRTAHVCAALGEPA
PGGLDPRAGMLSVGPNTNVLGHAGQTLALVEGGGANYRLTEDLDTVGTCDFDGTLFGGYTAHPHRDPRTGELHAVSYSFG
RGRRVQYSVIDTAGRARRTVDIEVSGSPMMHDFSLTDEYVVIYDLPVTFDPVQVMPADVPRWLSAPARLVVQSLLGRVQL
PGPMATAMNRNRQPLHRMPYRWNDAYPARLGVMPRDGGNDEVRWFDIEPCYVYHPLNAYSEIRDGAKVLVLDVVRYSRMF
DRDLRGPGDTRPTLDRWTVNLTTGAVGSELRDDRSQEFPRINEALLGRRHRFGYTVGTDGGYPSDGASEMSTGLYKHDYA
TGSRRVAPLDPDLLIGEMCFVPNPAGGQDGAEDDGILMGFGYHRGRDEGQLVLLDAQSLEQVATVHLPQRVPMGFHGNWV
PAG

Sequences:

>Translated_483_residues
MRAEVTAFDLPVTGRIPDHLDGRYLRNGPNPVAEVDPATYHWFSGDGMVHGVALRDGRARWYRNRWVRTAHVCAALGEPA
PGGLDPRAGMLSVGPNTNVLGHAGQTLALVEGGGANYRLTEDLDTVGTCDFDGTLFGGYTAHPHRDPRTGELHAVSYSFG
RGRRVQYSVIDTAGRARRTVDIEVSGSPMMHDFSLTDEYVVIYDLPVTFDPVQVMPADVPRWLSAPARLVVQSLLGRVQL
PGPMATAMNRNRQPLHRMPYRWNDAYPARLGVMPRDGGNDEVRWFDIEPCYVYHPLNAYSEIRDGAKVLVLDVVRYSRMF
DRDLRGPGDTRPTLDRWTVNLTTGAVGSELRDDRSQEFPRINEALLGRRHRFGYTVGTDGGYPSDGASEMSTGLYKHDYA
TGSRRVAPLDPDLLIGEMCFVPNPAGGQDGAEDDGILMGFGYHRGRDEGQLVLLDAQSLEQVATVHLPQRVPMGFHGNWV
PAG
>Mature_483_residues
MRAEVTAFDLPVTGRIPDHLDGRYLRNGPNPVAEVDPATYHWFSGDGMVHGVALRDGRARWYRNRWVRTAHVCAALGEPA
PGGLDPRAGMLSVGPNTNVLGHAGQTLALVEGGGANYRLTEDLDTVGTCDFDGTLFGGYTAHPHRDPRTGELHAVSYSFG
RGRRVQYSVIDTAGRARRTVDIEVSGSPMMHDFSLTDEYVVIYDLPVTFDPVQVMPADVPRWLSAPARLVVQSLLGRVQL
PGPMATAMNRNRQPLHRMPYRWNDAYPARLGVMPRDGGNDEVRWFDIEPCYVYHPLNAYSEIRDGAKVLVLDVVRYSRMF
DRDLRGPGDTRPTLDRWTVNLTTGAVGSELRDDRSQEFPRINEALLGRRHRFGYTVGTDGGYPSDGASEMSTGLYKHDYA
TGSRRVAPLDPDLLIGEMCFVPNPAGGQDGAEDDGILMGFGYHRGRDEGQLVLLDAQSLEQVATVHLPQRVPMGFHGNWV
PAG

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 53321; Mature: 53321

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEVTAFDLPVTGRIPDHLDGRYLRNGPNPVAEVDPATYHWFSGDGMVHGVALRDGRAR
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCHH
WYRNRWVRTAHVCAALGEPAPGGLDPRAGMLSVGPNTNVLGHAGQTLALVEGGGANYRLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEECCCCEEEEEECCCCCEEEC
EDLDTVGTCDFDGTLFGGYTAHPHRDPRTGELHAVSYSFGRGRRVQYSVIDTAGRARRTV
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEE
DIEVSGSPMMHDFSLTDEYVVIYDLPVTFDPVQVMPADVPRWLSAPARLVVQSLLGRVQL
EEEECCCCCEEEECCCCCEEEEEECCCCCCCCEECCCCCCHHHCHHHHHHHHHHHCCCCC
PGPMATAMNRNRQPLHRMPYRWNDAYPARLGVMPRDGGNDEVRWFDIEPCYVYHPLNAYS
CCCHHHHHCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEEECCCHHH
EIRDGAKVLVLDVVRYSRMFDRDLRGPGDTRPTLDRWTVNLTTGAVGSELRDDRSQEFPR
HHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCH
INEALLGRRHRFGYTVGTDGGYPSDGASEMSTGLYKHDYATGSRRVAPLDPDLLIGEMCF
HHHHHHCCHHHCCEEECCCCCCCCCCHHHHHCCCEEECCCCCCCEECCCCCCCEEECEEE
VPNPAGGQDGAEDDGILMGFGYHRGRDEGQLVLLDAQSLEQVATVHLPQRVPMGFHGNWV
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCC
PAG
CCC
>Mature Secondary Structure
MRAEVTAFDLPVTGRIPDHLDGRYLRNGPNPVAEVDPATYHWFSGDGMVHGVALRDGRAR
CCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEECCCHH
WYRNRWVRTAHVCAALGEPAPGGLDPRAGMLSVGPNTNVLGHAGQTLALVEGGGANYRLT
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCEEECCCCEEEEEECCCCCEEEC
EDLDTVGTCDFDGTLFGGYTAHPHRDPRTGELHAVSYSFGRGRRVQYSVIDTAGRARRTV
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCEEEE
DIEVSGSPMMHDFSLTDEYVVIYDLPVTFDPVQVMPADVPRWLSAPARLVVQSLLGRVQL
EEEECCCCCEEEECCCCCEEEEEECCCCCCCCEECCCCCCHHHCHHHHHHHHHHHCCCCC
PGPMATAMNRNRQPLHRMPYRWNDAYPARLGVMPRDGGNDEVRWFDIEPCYVYHPLNAYS
CCCHHHHHCCCCCCHHHCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCEEEEECCCHHH
EIRDGAKVLVLDVVRYSRMFDRDLRGPGDTRPTLDRWTVNLTTGAVGSELRDDRSQEFPR
HHCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCH
INEALLGRRHRFGYTVGTDGGYPSDGASEMSTGLYKHDYATGSRRVAPLDPDLLIGEMCF
HHHHHHCCHHHCCEEECCCCCCCCCCHHHHHCCCEEECCCCCCCEECCCCCCCEEECEEE
VPNPAGGQDGAEDDGILMGFGYHRGRDEGQLVLLDAQSLEQVATVHLPQRVPMGFHGNWV
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCC
PAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]