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The map label for this gene is mshA

Identifier: 41410077

GI number: 41410077

Start: 4437874

End: 4439199

Strand: Direct

Name: mshA

Synonym: MAP3979

Alternate gene names: 41410077

Gene position: 4437874-4439199 (Clockwise)

Preceding gene: 41410076

Following gene: 41410078

Centisome position: 91.89

GC content: 73.38

Gene sequence:

>1326_bases
GTGTGCTGCGCACTTGGGCCCGGTGGCGAACCATCCTGTAAAGATGACAGAGTGCGGCACGATGACGTCTTCCGGCTGAA
TGAGCCGCGCCGGGTGGCCGTGCTGGCGGTCCACACCTCGCCACTGGCCCAGCCCGGCACCGGCGACGCGGGCGGCATGA
ACGTCTACGTGCTGCAGACCGCCCTGCACCTGGCACGCCGCGGCATCGAGGTGGAGATCTTCACCCGGGCGACCGCCTCG
GCCGACCCGCCGGTGCAGCGGGTGGCGCCCGGCGTGCTGGTGCGCAACGTGGTGGCCGGGCCGTTCGAGGGCCTGGACAA
ATACGATCTGCCCACCCAGCTGTGCGCGTTCGCGGCCGGAGTGCTGCGCGCCGAAGCGTCGCACGAGCCGGGTTACTACG
ACATCGTGCACTCGCACTACTGGCTGTCCGGTCAGGTCGGCTGGCTGGCGCGCGACCGCTGGGCGGTGCCGCTGGTGCAC
ACCGCGCACACCCTGGCCGCGGTGAAAAATGCCGCGCTGGCGCAAGGGGATTCGCCCGAGCCGCCGCTGCGCACGGTGGG
CGAGCAGCAGGTGGTCGACGAGGCCGACCGGCTGATCGTCAACACCGACGACGAAGCGCGGCAACTGATTTCGATCCACC
ACGCCGACCCGGCCAGGATCGACGTCGTGCATCCCGGGGTGGACCTCGACGTGTTCCGACCCGGCGACCGTCGCGCCGCC
CGGGCCGCGCTGGGGCTGCCGCTCGACAAGGACATCGTGGCGTTCGTCGGCCGCATCCAGCCGCTGAAGGCCCCCGACAT
CGTCTTGCGTGCCGCCGCGAAACTGCCCGGGGTGCGCATCGTGGTGGCCGGCGGGCCGTCGGGCACCGGCCTGGCCTCGC
CGGACGGATTGGCCCGGCTGGCCGACGAACTCGGCATCTCCGCGCGGGTCACGTTCCTGCCCCCGCAGTCCCGCCCGAAC
CTGGCCACTCTGTTCCAGGCGGCCAATCTTGTTGCAGTGCCGAGCTATTCGGAGTCCTTCGGCCTGGTGGCGCTGGAGGC
GCAGGCGTGCGGCACCCCGGTGGCCGCGGCCGCGGTCGGCGGGCTGCCGGTGGCCGTGCGCGACGGCGTCACCGGCACCC
TGGTGGCCGGGCACGACGTCGACCACTGGGCCGACGCGCTGGCCGGGCTGCTGCGCGCGCCCGCCCCGGCGGCCGCGGCG
ATGAGCCGCGCGGCGGCCGCGCACGCCGCCACCTTCTCCTGGGACCACACCACGGACGCGCTGCTGGCCAGCTACCGGCG
CGCGATCCGCGAGTACACGACCGAGCGCCGGGGGGTGGGCGCATGA

Upstream 100 bases:

>100_bases
GTACGCCGATCCGCTGAGCGCGATGCGGCGGGCCGGGGCGCTGGACGCCCGGCTGCGCGAGGTCGCGCGGGACGAGTCGT
CGGCCTGACCCGACGCCGCC

Downstream 100 bases:

>100_bases
GCGCCACCGTCGAGCGGGTGATCGAGGACACGCTGCAGGCCAGCGGCCTGACCTACTCGAAACACGCTGGGGCGCATGGC
GGTCCGTCGGGCCTGGTGGT

Product: hypothetical protein

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MCCALGPGGEPSCKDDRVRHDDVFRLNEPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATAS
ADPPVQRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVH
TAHTLAAVKNAALAQGDSPEPPLRTVGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPGDRRAA
RAALGLPLDKDIVAFVGRIQPLKAPDIVLRAAAKLPGVRIVVAGGPSGTGLASPDGLARLADELGISARVTFLPPQSRPN
LATLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRDGVTGTLVAGHDVDHWADALAGLLRAPAPAAAA
MSRAAAAHAATFSWDHTTDALLASYRRAIREYTTERRGVGA

Sequences:

>Translated_441_residues
MCCALGPGGEPSCKDDRVRHDDVFRLNEPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATAS
ADPPVQRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVH
TAHTLAAVKNAALAQGDSPEPPLRTVGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPGDRRAA
RAALGLPLDKDIVAFVGRIQPLKAPDIVLRAAAKLPGVRIVVAGGPSGTGLASPDGLARLADELGISARVTFLPPQSRPN
LATLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRDGVTGTLVAGHDVDHWADALAGLLRAPAPAAAA
MSRAAAAHAATFSWDHTTDALLASYRRAIREYTTERRGVGA
>Mature_441_residues
MCCALGPGGEPSCKDDRVRHDDVFRLNEPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQTALHLARRGIEVEIFTRATAS
ADPPVQRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAGVLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVH
TAHTLAAVKNAALAQGDSPEPPLRTVGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPGDRRAA
RAALGLPLDKDIVAFVGRIQPLKAPDIVLRAAAKLPGVRIVVAGGPSGTGLASPDGLARLADELGISARVTFLPPQSRPN
LATLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVGGLPVAVRDGVTGTLVAGHDVDHWADALAGLLRAPAPAAAA
MSRAAAAHAATFSWDHTTDALLASYRRAIREYTTERRGVGA

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily

Homologues:

Organism=Escherichia coli, GI1790061, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHA_MYCPA (Q73SU4)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_962913.1
- ProteinModelPortal:   Q73SU4
- SMR:   Q73SU4
- EnsemblBacteria:   EBMYCT00000037683
- GeneID:   2717714
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP3979
- NMPDR:   fig|262316.1.peg.3979
- GeneTree:   EBGT00050000015521
- HOGENOM:   HBG726846
- OMA:   PLKAPDV
- ProtClustDB:   CLSK871811
- HAMAP:   MF_01695
- InterPro:   IPR001296
- InterPro:   IPR017814
- TIGRFAMs:   TIGR03449

Pfam domain/function: PF00534 Glycos_transf_1

EC number: =2.4.1.250

Molecular weight: Translated: 46334; Mature: 46334

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00039 DEAD_ATP_HELICASE

Important sites: BINDING 38-38 BINDING 52-52 BINDING 107-107 BINDING 140-140 BINDING 164-164 BINDING 184-184 BINDING 258-258 BINDING 263-263 BINDING 316-316 BINDING 338-338 BINDING 346-346

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCCALGPGGEPSCKDDRVRHDDVFRLNEPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQT
CEECCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHH
ALHLARRGIEVEIFTRATASADPPVQRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAG
HHHHHHCCCEEEEEEECCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAQGDSPE
HHHHCCCCCCCEEEEEECEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PPLRTVGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPGDRRAA
CCHHHCCHHHHHHHHCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCHHHH
RAALGLPLDKDIVAFVGRIQPLKAPDIVLRAAAKLPGVRIVVAGGPSGTGLASPDGLARL
HHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
ADELGISARVTFLPPQSRPNLATLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVG
HHHCCCEEEEEEECCCCCCCHHHHHHHCCEEEECCCCCCCCEEEEEHHHCCCCHHHHHHC
GLPVAVRDGVTGTLVAGHDVDHWADALAGLLRAPAPAAAAMSRAAAAHAATFSWDHTTDA
CCCEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCHHHH
LLASYRRAIREYTTERRGVGA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCCALGPGGEPSCKDDRVRHDDVFRLNEPRRVAVLAVHTSPLAQPGTGDAGGMNVYVLQT
CEECCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCCCCCCCCCCCEEEHHHHH
ALHLARRGIEVEIFTRATASADPPVQRVAPGVLVRNVVAGPFEGLDKYDLPTQLCAFAAG
HHHHHHCCCEEEEEEECCCCCCCCHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VLRAEASHEPGYYDIVHSHYWLSGQVGWLARDRWAVPLVHTAHTLAAVKNAALAQGDSPE
HHHHCCCCCCCEEEEEECEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
PPLRTVGEQQVVDEADRLIVNTDDEARQLISIHHADPARIDVVHPGVDLDVFRPGDRRAA
CCHHHCCHHHHHHHHCEEEEECCHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCHHHH
RAALGLPLDKDIVAFVGRIQPLKAPDIVLRAAAKLPGVRIVVAGGPSGTGLASPDGLARL
HHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
ADELGISARVTFLPPQSRPNLATLFQAANLVAVPSYSESFGLVALEAQACGTPVAAAAVG
HHHCCCEEEEEEECCCCCCCHHHHHHHCCEEEECCCCCCCCEEEEEHHHCCCCHHHHHHC
GLPVAVRDGVTGTLVAGHDVDHWADALAGLLRAPAPAAAAMSRAAAAHAATFSWDHTTDA
CCCEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCHHHH
LLASYRRAIREYTTERRGVGA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA