Click here to switch to the map view.

The map label for this gene is murB

Identifier: 41410073

GI number: 41410073

Start: 4433084

End: 4434202

Strand: Direct

Name: murB

Synonym: MAP3975

Alternate gene names: 41410073

Gene position: 4433084-4434202 (Clockwise)

Preceding gene: 41410069

Following gene: 41410074

Centisome position: 91.79

GC content: 72.3

Gene sequence:

>1119_bases
ATGAAATCCAGCGGTGCAGGTGCGGCGTTCGCCGGCGCGTCAGTGGCCGACGCGGCGCCGCTGGCGCCGCTGACCACGCT
GCGGGTCGGACCCACCGCGCGCCGGCTGATCACCTGTGCCAGCAGCGAACAGGTGATCGCCACGTTGCGCCGGCTGGACA
CCGAAAGGCTTGCCGGACAACGTGATCCGGTGCTGGTGTTCGCCGGCGGCTCGAACCTGGTGATCTCCGACGCGCTGAGT
GACCTGACCGCGGTGCGGCTGGCCAACGACGGAATCACCGTCGAGGGCAATCTGGTGCGCGCCCAGGCGGGGGCGGTGTG
GGACGACGTCGTGCTCACCGCCATCGAGCACGGCCTGGGCGGGCTGGAATGCCTGTCCGGCATCCCCGGCTCGGCCGGGG
CCACCCCGATCCAAAACGTCGGGGCGTACGGCGCCGAGGTCTCCGACACCCTCACCCGGGTCAGGGTGCTGGACCGCGGC
AGCGGGCAGGTGCGCTGGGTGCCCGGCACCGAGCTGGAATTCGGTTACCGCACCAGCGTGTTCAAACGGCGCGCCGACGA
CGGGCTCGAAATCCCTTCCGTGGTACTGGAAGTCGAGTTCGCGCTCGATGCGTCGGGGCGCAGCGCGCCGGTGCGCTACG
GCGAGCTGGCCGCCGAATTGAAGGTGCCCGTCGGCCAGCGCGCCGACCCGCGCACGGTCCGCGAGGCGGTGCTGGCGCTG
CGGGCGCGCAAGGGCATGGTGCTCGACGCCGCCGACCACGACACCTGGAGCGTGGGGTCGTTCTTCACCAACCCGGTGGT
GGCCCCCGACGTCTACGAGCGGCTGGCCGGGTCCGTCGACGGGCCGGTGCCGCACTATCCGGCCCCGGGCGGGGTCAAGC
TGGCCGCCGGCTGGCTGGTGGAGCGGGCGGGTTTCGGCAAGGGCTATCCGGTCCCGGACCCGGGCGGCCCGGAAGCGCCC
TGCCGGCTGTCCACCAAGCACGCGTTGGCGCTGACCAACCGCGGCACGGCCCGCAGCGACGACGTGATCGCCCTGGCCCG
GACCATCCGGGACGGGGTGCGGTCTGTGTTTGGCATCACACTGGTGCCCGAGCCCGTCCTGCTCGGTTGCAGGCTGTAG

Upstream 100 bases:

>100_bases
GCATCGGTGAAGGCCCGGTGCACCTCGTCAACGCTGCCGTCGTAGTGGGCCGACAAGTCGAATGAGCGCGGCATAGCAGG
TCAGGCTACCGTTACGGGCC

Downstream 100 bases:

>100_bases
CGGCAAAATTTGCCGACGCGCGCCCGGCGCCCGATTTGTCGCGGCAGGGTTGCCCGATTTTCCCCGGTATCTTTGATTTT
CGTGACCCCGTCCAGCGCCC

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKSSGAGAAFAGASVADAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQRDPVLVFAGGSNLVISDALS
DLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATPIQNVGAYGAEVSDTLTRVRVLDRG
SGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVLEVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLAL
RARKGMVLDAADHDTWSVGSFFTNPVVAPDVYERLAGSVDGPVPHYPAPGGVKLAAGWLVERAGFGKGYPVPDPGGPEAP
CRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL

Sequences:

>Translated_372_residues
MKSSGAGAAFAGASVADAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQRDPVLVFAGGSNLVISDALS
DLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATPIQNVGAYGAEVSDTLTRVRVLDRG
SGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVLEVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLAL
RARKGMVLDAADHDTWSVGSFFTNPVVAPDVYERLAGSVDGPVPHYPAPGGVKLAAGWLVERAGFGKGYPVPDPGGPEAP
CRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL
>Mature_372_residues
MKSSGAGAAFAGASVADAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQRDPVLVFAGGSNLVISDALS
DLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLGGLECLSGIPGSAGATPIQNVGAYGAEVSDTLTRVRVLDRG
SGQVRWVPGTELEFGYRTSVFKRRADDGLEIPSVVLEVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLAL
RARKGMVLDAADHDTWSVGSFFTNPVVAPDVYERLAGSVDGPVPHYPAPGGVKLAAGWLVERAGFGKGYPVPDPGGPEAP
CRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGITLVPEPVLLGCRL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=362, Percent_Identity=31.4917127071823, Blast_Score=133, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38782; Mature: 38782

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSSGAGAAFAGASVADAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQ
CCCCCCCCEECCCCCCCCCCCCCEEEEECCCCHHHEEEECCCHHHHHHHHHHHHHHHCCC
RDPVLVFAGGSNLVISDALSDLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLG
CCCEEEEECCCCEEEHHHHHHHEEEEEECCCEEEECCEEEECCCCHHHHHHHHHHHHCCC
GLECLSGIPGSAGATPIQNVGAYGAEVSDTLTRVRVLDRGSGQVRWVPGTELEFGYRTSV
HHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHEECCCCEEEECCCCCCCCCHHHHH
FKRRADDGLEIPSVVLEVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLAL
HHHHCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHH
RARKGMVLDAADHDTWSVGSFFTNPVVAPDVYERLAGSVDGPVPHYPAPGGVKLAAGWLV
HHHCCCEEECCCCCCEECCCHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHH
ERAGFGKGYPVPDPGGPEAPCRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGIT
HHCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEE
LVPEPVLLGCRL
ECCCCCEECCCC
>Mature Secondary Structure
MKSSGAGAAFAGASVADAAPLAPLTTLRVGPTARRLITCASSEQVIATLRRLDTERLAGQ
CCCCCCCCEECCCCCCCCCCCCCEEEEECCCCHHHEEEECCCHHHHHHHHHHHHHHHCCC
RDPVLVFAGGSNLVISDALSDLTAVRLANDGITVEGNLVRAQAGAVWDDVVLTAIEHGLG
CCCEEEEECCCCEEEHHHHHHHEEEEEECCCEEEECCEEEECCCCHHHHHHHHHHHHCCC
GLECLSGIPGSAGATPIQNVGAYGAEVSDTLTRVRVLDRGSGQVRWVPGTELEFGYRTSV
HHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHEECCCCEEEECCCCCCCCCHHHHH
FKRRADDGLEIPSVVLEVEFALDASGRSAPVRYGELAAELKVPVGQRADPRTVREAVLAL
HHHHCCCCCCCCEEEEEEEEEECCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHH
RARKGMVLDAADHDTWSVGSFFTNPVVAPDVYERLAGSVDGPVPHYPAPGGVKLAAGWLV
HHHCCCEEECCCCCCEECCCHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHH
ERAGFGKGYPVPDPGGPEAPCRLSTKHALALTNRGTARSDDVIALARTIRDGVRSVFGIT
HHCCCCCCCCCCCCCCCCCCCEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCEE
LVPEPVLLGCRL
ECCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA