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The map label for this gene is mmpL4_6

Identifier: 41409988

GI number: 41409988

Start: 4352250

End: 4355117

Strand: Direct

Name: mmpL4_6

Synonym: MAP3890

Alternate gene names: 41409988

Gene position: 4352250-4355117 (Clockwise)

Preceding gene: 41409987

Following gene: 41409989

Centisome position: 90.11

GC content: 64.37

Gene sequence:

>2868_bases
ATGAGTAACCCGCACGCGCAGTCCCGACTCCCGGTCATTCCCAGGCTCATTCGCGTGCTGTCGCTGCCGATCACCCTGGG
CTGGGTGTTCGTCGCGGTCGCCCTGGGGGTGCTGTCGCCGTCGCTCGACGACGTCGCGTCCCAGCACTCGGTGCCGATGA
CCCCGCGGGACGCGCCGGCGTTCAAGTCGATGATGCACATCGGCGACAAGTTCAACGAGTTCCACACCGATTCCACGGCG
ATGGTGGTCCTGGAGGGGAAGGACAAACTCGGCGACAGCGCGCACGAGTTCTACGACCGCATCGTGCGCAAACTGCGGGA
CGACCATCAGCACGTCCAGAACATCCAGGACTTCTGGAGTGATCCGCTGACCGCCGCCGGCTCGCAGAGCCCCGACGGCA
AGTCCGCCTACGTGCAGGTCTTCCTCAACGGCGCCCAGGGAACCACGCCCAGCTACGAGTCGGTCGCCGCGGTGCGCAAG
ATCGTCGACAGCACACCCGCACCGCCCGGCGTCAAGGCGTACGTGGCCGGCAACACCGTGCTGAACGCCGACACCAGCAT
CGTCGGCCATAAGAGCATGGCGACGATGGCGCTGGTCTCCATCGTGGTCATCTTCGTGATGCTGCTGGTGGTGTACCGGT
CGATCGTCACCACCGTGCTGAGCCTGGTGATCATCGGCATAGAACTCTTCGCGGCCCAGGGCATTACGGCGACGGCAGGC
AATCTCAACATCATCGGCCTGACGCCCTACGCGGTCAGCATGATCACCATGCTCAGCATCGCCGCGGGAACCGACTACGT
CATCTTCCTGCTGGGCCGCTATCACGAAGCGCGCTCCTTCGGCCAGGACAGGGAGGAGGCCTTCTACACCGCCTATCACG
GTGTCTCGCACGTCATCCTGGGCTCGGGCCTGACCATCGCGGGCGCCTGCCTGTGCCTGACGGCGGCCCGGCTGCCGTAT
TTCCAGACCATGGGGTTGCCCTGCGCGATAGCGATGGTGGTCATCGTGTTGGCGGCGCTGACCCTGGCGCCGGCGATCCT
GGCGGTCGGCTCGCGGTTCGGCCTGTTCGATCCCAAACGCGCGATCGACGTGCGGGGCTGGCGCAAGGTGGGCACCGCCG
TGGTGCGCTGGCCCAAGCCGATCATCGTGGTGACCGCGGCGATCGCGGTGATCGGGTTCATCAGCCTGCTGACATACGTG
CCGAACTACGACGACCAGAAATTCACGCCGAAGGACATGCCCGCCAACGCCGCGATGACGGCCGCCGAACGGCACTTCTC
CCAGGCCCGGATGAACCCGGAATTGCTGATGGTGGAGGCCGACCACGATCTGCGCGACCCGGCCGACATGCTCGTCGTCG
ACCGAATCGCCAAGAGCGTCTTTCATCTTCGCGGCATCGAGCGGGTCCAGACCATCACCCGGCCGCTGGGGGCGCCGATC
GAGCACAGCTCGATCCCGTTCCAGATCGCCATGCAGAACTCGGGCACGCTGCAGACGGCCAAGTTCATGAACGACACCAT
GGCGAACATGCTCGAGCAGGCCGACGAGCTGGACAAGACGATCGCCGTGATGGAGCACATGTACGGCGTCATGAAGGAAC
TCACCGCCACCACGCACAGCATGGTCGGCCGCACCCACGAGATGGTGGACACCACCAACGAATTACGGGATCGCATCGCC
GATTTCGACGACTTCTTCCGGCCCATCAGAAGCTACTTCTACTGGGAGAAACACTGTTTCGACATCCCGGTGTGCTGGTC
GATGCGCTCGCTGTTCGACGCGCTCGACGGCATCGACGAGCTCTCCGACCAGATATCGGGGCTCACCATCGATCTCGATC
ACATGGATCGGTTGATGCCGCAACTGCTGGCCGATTTCCCGAAAACCATCGACTCGATGAAGACGATGCGCGACTTCATG
CTGTCCACCCATTCCACGATGGCCGGCATCCAGGCCCACCAGCAGGAGGCCGCCGAGGGCTCGACCCTGATGGGGCAATA
CTTCGACGAGGCCAAGAACGACGACTCGTTCTACCTGCCGCCGGAAGTCTTCAAAAACCCCGACTTCAAACGCGGGCTGA
AGATGTTCGTCTCACCCGACGGCACCGCGGTGCGGTTCATCATCACCCACCAGGGCGATCCGGCCTCGGTCGAGGGAATC
AAACACGTCGCCGGTGTCAAGGACGCGGTCGCCGACGCCATCAAGGGCACCCCGCTGGAGAGCTCCAAGGTGTACCTGGC
CGGGACCGCGTCGATGTACTCCGACATGCAAGAAGGCGTCATCATCGACCTCCTGGTCGCCGGAATCTCCTGTCTCATCC
TGATTTTCACGATCATGTTGATCATCACCCGCAGTGTGGTCGCGGCGTTGGTCATCGTCGGCACCGTCGCCGCCTCGCTG
GGCACCGCCTGCGGCCTGTCGGTGCTGATGTGGCAGGACCTCATCGGGCTCGGCGTGCAATGGATCGTACTGCCGCTGTC
CATCGTGATCCTGCTGGCGGTGGGATCGGACTACAACCTGCTGCTGGTGTCGCGACTCAAGGAGGAGATCCCCGCGGGCC
TCAACACCGGCATCATCCGCGGCATGGGCGCCTCGGGCCGGGTCGTCACCGCCGCCGGGCTGGTGTTCGCCTTCACCATG
GCGTCGATGATCGTCAGCCAGCTGCGGGTGATCGGCGAGCTCGGCACCACCATCGCGCTGGGCCTGCTCGTCGACACCCT
GATCGTGCGGTCCTTCATGACGCCTTCGATCGCCGCCGCGCTCGGGCACTGGTTCTGGTGGCCGATCAACACCATCCGCA
TGACCCGACGCACACACCACGACGAGGAGGCACACACGGCGCCGATCCGGCAGCCGGCTCTAAGGTGA

Upstream 100 bases:

>100_bases
TGCATGCACTGCGGTGCCGGGTCATCGTCGACGACCAGGTCCGCGACGACCGCAACACCAACGACTACCAACCGTTCATC
TACTGCTTGGTGAAATCCGT

Downstream 100 bases:

>100_bases
ACTGCGTGGGGCAGCCGCAATCGCAGATGGAGCCGGAATCCAAGCTTCGCCAGCGCACCGAGGGGCGACTCGATCGCTCG
CGCGACCCCGCGATCCTCGA

Product: MmpL4_6

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 955; Mature: 954

Protein sequence:

>955_residues
MSNPHAQSRLPVIPRLIRVLSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKFNEFHTDSTA
MVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSDPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRK
IVDSTPAPPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIELFAAQGITATAG
NLNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQDREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARLPY
FQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKRAIDVRGWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYV
PNYDDQKFTPKDMPANAAMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPI
EHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADELDKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIA
DFDDFFRPIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFM
LSTHSTMAGIQAHQQEAAEGSTLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEGI
KHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIMLIITRSVVAALVIVGTVAASL
GTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGRVVTAAGLVFAFTM
ASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSIAAALGHWFWWPINTIRMTRRTHHDEEAHTAPIRQPALR

Sequences:

>Translated_955_residues
MSNPHAQSRLPVIPRLIRVLSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKFNEFHTDSTA
MVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSDPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRK
IVDSTPAPPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIELFAAQGITATAG
NLNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQDREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARLPY
FQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKRAIDVRGWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYV
PNYDDQKFTPKDMPANAAMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPI
EHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADELDKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIA
DFDDFFRPIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFM
LSTHSTMAGIQAHQQEAAEGSTLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEGI
KHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIMLIITRSVVAALVIVGTVAASL
GTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGRVVTAAGLVFAFTM
ASMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSIAAALGHWFWWPINTIRMTRRTHHDEEAHTAPIRQPALR
>Mature_954_residues
SNPHAQSRLPVIPRLIRVLSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPAFKSMMHIGDKFNEFHTDSTAM
VVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWSDPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKI
VDSTPAPPGVKAYVAGNTVLNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIELFAAQGITATAGN
LNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQDREEAFYTAYHGVSHVILGSGLTIAGACLCLTAARLPYF
QTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKRAIDVRGWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVP
NYDDQKFTPKDMPANAAMTAAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPIE
HSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADELDKTIAVMEHMYGVMKELTATTHSMVGRTHEMVDTTNELRDRIAD
FDDFFRPIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDELSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFML
STHSTMAGIQAHQQEAAEGSTLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEGIK
HVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIMLIITRSVVAALVIVGTVAASLG
TACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNLLLVSRLKEEIPAGLNTGIIRGMGASGRVVTAAGLVFAFTMA
SMIVSQLRVIGELGTTIALGLLVDTLIVRSFMTPSIAAALGHWFWWPINTIRMTRRTHHDEEAHTAPIRQPALR

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 104195; Mature: 104063

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPHAQSRLPVIPRLIRVLSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCHH
FKSMMHIGDKFNEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWS
HHHHHHHHHHHHHHCCCCEEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTPAPPGVKAYVAGNTV
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCEE
LNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIELFAAQGITATAG
EECCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
NLNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQDREEAFYTAYHGVSHVIL
CEEEEEECHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GSGLTIAGACLCLTAARLPYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKR
CCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AIDVRGWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANAAMT
HHCCCHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
AAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPI
HHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADELDKTIAVMEHMYGVMKELTATTHS
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVGRTHEMVDTTNELRDRIADFDDFFRPIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEG
HHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEGI
CHHHHHHHHHCCCCCCEECCHHHHCCCCHHHCHHEEECCCCCEEEEEEEECCCCCHHHHH
KHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIML
HHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCH
LLVSRLKEEIPAGLNTGIIRGMGASGRVVTAAGLVFAFTMASMIVSQLRVIGELGTTIAL
HHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLVDTLIVRSFMTPSIAAALGHWFWWPINTIRMTRRTHHDEEAHTAPIRQPALR
HHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCCCC
>Mature Secondary Structure 
SNPHAQSRLPVIPRLIRVLSLPITLGWVFVAVALGVLSPSLDDVASQHSVPMTPRDAPA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCCHH
FKSMMHIGDKFNEFHTDSTAMVVLEGKDKLGDSAHEFYDRIVRKLRDDHQHVQNIQDFWS
HHHHHHHHHHHHHHCCCCEEEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DPLTAAGSQSPDGKSAYVQVFLNGAQGTTPSYESVAAVRKIVDSTPAPPGVKAYVAGNTV
CCCCCCCCCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCEE
LNADTSIVGHKSMATMALVSIVVIFVMLLVVYRSIVTTVLSLVIIGIELFAAQGITATAG
EECCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
NLNIIGLTPYAVSMITMLSIAAGTDYVIFLLGRYHEARSFGQDREEAFYTAYHGVSHVIL
CEEEEEECHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GSGLTIAGACLCLTAARLPYFQTMGLPCAIAMVVIVLAALTLAPAILAVGSRFGLFDPKR
CCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AIDVRGWRKVGTAVVRWPKPIIVVTAAIAVIGFISLLTYVPNYDDQKFTPKDMPANAAMT
HHCCCHHHHHCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
AAERHFSQARMNPELLMVEADHDLRDPADMLVVDRIAKSVFHLRGIERVQTITRPLGAPI
HHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EHSSIPFQIAMQNSGTLQTAKFMNDTMANMLEQADELDKTIAVMEHMYGVMKELTATTHS
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MVGRTHEMVDTTNELRDRIADFDDFFRPIRSYFYWEKHCFDIPVCWSMRSLFDALDGIDE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LSDQISGLTIDLDHMDRLMPQLLADFPKTIDSMKTMRDFMLSTHSTMAGIQAHQQEAAEG
HHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STLMGQYFDEAKNDDSFYLPPEVFKNPDFKRGLKMFVSPDGTAVRFIITHQGDPASVEGI
CHHHHHHHHHCCCCCCEECCHHHHCCCCHHHCHHEEECCCCCEEEEEEEECCCCCHHHHH
KHVAGVKDAVADAIKGTPLESSKVYLAGTASMYSDMQEGVIIDLLVAGISCLILIFTIML
HHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
IITRSVVAALVIVGTVAASLGTACGLSVLMWQDLIGLGVQWIVLPLSIVILLAVGSDYNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCH
LLVSRLKEEIPAGLNTGIIRGMGASGRVVTAAGLVFAFTMASMIVSQLRVIGELGTTIAL
HHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLLVDTLIVRSFMTPSIAAALGHWFWWPINTIRMTRRTHHDEEAHTAPIRQPALR
HHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]