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The map label for this gene is ackA

Identifier: 41409984

GI number: 41409984

Start: 4347922

End: 4349085

Strand: Direct

Name: ackA

Synonym: MAP3886

Alternate gene names: 41409984

Gene position: 4347922-4349085 (Clockwise)

Preceding gene: 41409983

Following gene: 41409987

Centisome position: 90.02

GC content: 69.76

Gene sequence:

>1164_bases
GTGGACGGTAGCGACGGCGCGCGCCGGGTGCTGGTGATCAACTCCGGCTCGTCGTCGCTGAAGTTCCAGCTGGTCGATCC
CGAGTTCGGGGTGGCCGCCTCGACGGGCATCGTGGAACGCATCGGCGAGGAATCCTCGCCGGTCCCCGACCACGACGCCG
CGCTGCGCCGAGCGTTCGACATGCTGGCCGGCGACGGCGTCGACCTGAACACCGCCGGGCTGGTCGCGGTGGGTCATCGG
GTGGTGCACGGCGGCAACACCTTCTACCGGCCCACCGTGCTGGACGACGCGGTGATCGCCCGGCTGCACGAGCTGTCGGA
GTTGGCCCCGCTGCACAATCCGCCGGCGCTCCAGGGAATCGAAGTGGCCCGCCGGCTGTTGCCCGACATCGCGCACGTGG
CCGTCTTCGACACCGGGTTCTTCCACGACCTGCCGCCCGCGGCGGCGACCTACGCCATCGACCGCGAATTGGCCGATCGC
TGGCAGATCCGCCGGTACGGGTTCCACGGCACCTCGCACCGCTACGTCAGCGAGCAGGCCGCGGCCTTCCTGGATCGGCC
GCTGCGCGGCCTGAAACAGATCGTGCTGCACCTGGGCAACGGCTGCTCGGCGTCGGCGATCGCCGGCACCCGGCCCCTCG
ACACCTCGATGGGGTTGACGCCGCTGGAGGGACTGGTGATGGGAACCCGCAGCGGTGACATCGATCCCAGCATCGTCAGC
TATCTGTGCCACACGGCCGGGATGGGGGTGGACGACGTCGAGTCGATGCTCAACCACCGCTCGGGGGTGGTGGGGCTGTC
CGGCGTGCGGGACTTCCGCCGGCTGCGCGAACTCATCGAATCCGGTGACGGCGCAGCGCAATTGGCCTACAGCGTGTTCA
CGCACCGGCTGCGCAAGTACATCGGAGCCTACCTGGCGGTGCTGGGCCACACCGACGTCATCAGCTTCACCGCCGGCATC
GGTGAGAACGACGCCGCGGTGCGCCGCGACGCGGTGTCCGGCATGGAGGAGCTGGGCATCGTGCTCGACGAGCGCCGCAA
CCTCGCCGGGGGCAAAGGGGCACGCCAGATCTCGGCCGACGACTCGCCGATCACGGTGCTGGTGGTCCCCACCAACGAAG
AGCTGGCCATCGCCCGTGACTGCGTGCGGGTGCTAGGCGGATAG

Upstream 100 bases:

>100_bases
GGCCTGCGCAAGCCGGTCAACGACCTGTCGCGGGGTGCGCTGGTCGAAGACATCGTGAACACCATTGCCATCACCGCGAT
TCAGGCGCAGGGGTTGCCCG

Downstream 100 bases:

>100_bases
GAAGCCGAGGTCGCGGCGGCCGGCGCCGACCGAGGGCGCGGGATCGGTGCCGACGGTGCGTGCCAGCAGCTCGTGGTAGA
TGTCGCGAAAATCGGTGGTG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MDGSDGARRVLVINSGSSSLKFQLVDPEFGVAASTGIVERIGEESSPVPDHDAALRRAFDMLAGDGVDLNTAGLVAVGHR
VVHGGNTFYRPTVLDDAVIARLHELSELAPLHNPPALQGIEVARRLLPDIAHVAVFDTGFFHDLPPAAATYAIDRELADR
WQIRRYGFHGTSHRYVSEQAAAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDIDPSIVS
YLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDGAAQLAYSVFTHRLRKYIGAYLAVLGHTDVISFTAGI
GENDAAVRRDAVSGMEELGIVLDERRNLAGGKGARQISADDSPITVLVVPTNEELAIARDCVRVLGG

Sequences:

>Translated_387_residues
MDGSDGARRVLVINSGSSSLKFQLVDPEFGVAASTGIVERIGEESSPVPDHDAALRRAFDMLAGDGVDLNTAGLVAVGHR
VVHGGNTFYRPTVLDDAVIARLHELSELAPLHNPPALQGIEVARRLLPDIAHVAVFDTGFFHDLPPAAATYAIDRELADR
WQIRRYGFHGTSHRYVSEQAAAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDIDPSIVS
YLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDGAAQLAYSVFTHRLRKYIGAYLAVLGHTDVISFTAGI
GENDAAVRRDAVSGMEELGIVLDERRNLAGGKGARQISADDSPITVLVVPTNEELAIARDCVRVLGG
>Mature_387_residues
MDGSDGARRVLVINSGSSSLKFQLVDPEFGVAASTGIVERIGEESSPVPDHDAALRRAFDMLAGDGVDLNTAGLVAVGHR
VVHGGNTFYRPTVLDDAVIARLHELSELAPLHNPPALQGIEVARRLLPDIAHVAVFDTGFFHDLPPAAATYAIDRELADR
WQIRRYGFHGTSHRYVSEQAAAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDIDPSIVS
YLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDGAAQLAYSVFTHRLRKYIGAYLAVLGHTDVISFTAGI
GENDAAVRRDAVSGMEELGIVLDERRNLAGGKGARQISADDSPITVLVVPTNEELAIARDCVRVLGG

Specific function: Involved In The Activation Of Acetate To Acetyl CoA And The Secretion Of Acetate. During Anaerobic Growth Of The Organism, This Enzyme Is Also Involved In The Synthesis Of Most Of The ATP Formed Catabolically. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788633, Length=397, Percent_Identity=42.3173803526448, Blast_Score=279, Evalue=2e-76,
Organism=Escherichia coli, GI145693184, Length=390, Percent_Identity=38.974358974359, Blast_Score=263, Evalue=1e-71,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000890
- InterPro:   IPR004372 [H]

Pfam domain/function: PF00871 Acetate_kinase [H]

EC number: =2.7.2.1 [H]

Molecular weight: Translated: 41310; Mature: 41310

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS01075 ACETATE_KINASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGSDGARRVLVINSGSSSLKFQLVDPEFGVAASTGIVERIGEESSPVPDHDAALRRAFD
CCCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MLAGDGVDLNTAGLVAVGHRVVHGGNTFYRPTVLDDAVIARLHELSELAPLHNPPALQGI
HHCCCCCCCCCCHHHHHCCEEEECCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
EVARRLLPDIAHVAVFDTGFFHDLPPAAATYAIDRELADRWQIRRYGFHGTSHRYVSEQA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDIDPSIVS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCHHHHH
YLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDGAAQLAYSVFTHRLRKY
HHHHHCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IGAYLAVLGHTDVISFTAGIGENDAAVRRDAVSGMEELGIVLDERRNLAGGKGARQISAD
HHHHHHHHCCCHHHHEECCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCC
DSPITVLVVPTNEELAIARDCVRVLGG
CCCEEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MDGSDGARRVLVINSGSSSLKFQLVDPEFGVAASTGIVERIGEESSPVPDHDAALRRAFD
CCCCCCCCEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
MLAGDGVDLNTAGLVAVGHRVVHGGNTFYRPTVLDDAVIARLHELSELAPLHNPPALQGI
HHCCCCCCCCCCHHHHHCCEEEECCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
EVARRLLPDIAHVAVFDTGFFHDLPPAAATYAIDRELADRWQIRRYGFHGTSHRYVSEQA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
AAFLDRPLRGLKQIVLHLGNGCSASAIAGTRPLDTSMGLTPLEGLVMGTRSGDIDPSIVS
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCHHHHH
YLCHTAGMGVDDVESMLNHRSGVVGLSGVRDFRRLRELIESGDGAAQLAYSVFTHRLRKY
HHHHHCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
IGAYLAVLGHTDVISFTAGIGENDAAVRRDAVSGMEELGIVLDERRNLAGGKGARQISAD
HHHHHHHHCCCHHHHEECCCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCC
DSPITVLVVPTNEELAIARDCVRVLGG
CCCEEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]