BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is yqjQ [H]

Identifier: 41409954

GI number: 41409954

Start: 4319080

End: 4319853

Strand: Direct

Name: yqjQ [H]

Synonym: MAP3856

Alternate gene names: 41409954

Gene position: 4319080-4319853 (Clockwise)

Preceding gene: 41409953

Following gene: 41409955

Centisome position: 89.43

GC content: 71.19

Gene sequence:

>774_bases
ATGCCTCGCCCCGTCGCCCTGATCACCGGGCCGACCTCCGGGATCGGCGCCGGATACGCGCGGCGCTACGCGAGCGACGG
CTACGACCTGGTGCTGGTCGCCCGCGACGTGGACCGGCTGACCGCGCTGGCCGGCGAACTGCGCGACCGGGCGGGCAACA
TCGAGATCCTGCCTGCCGACCTGGGCGATGCCGCCGACCGGCAACGGGTCGCTGAGCGCCTGGCCGCCGGAGTGCGGGTG
CTGGTCAACAACGCCGGCTTCGCCACCTCCGGCGACTTCTGGCACACCGACCCTGCGCTGCTGCAGTCCCAGCTCGACGT
CAACGTCACCGCCGTCATGCACCTCACCCGGGCGGCGCTGCCGGCCATGCTCGACGCCGGCGCCGGGACCGTCATCAACA
TCGCCAGCATCGCCGGGTTGCTGCCGGGGCGGGGGTCGACGTACTCGGCGTCCAAGGCGTGGGTGATCTCGTTCAGTGAG
GGCCTGTCCGTCGGGCTGCAGGGCACCGGCGTCTCCGTGCACGCGGTGTGCCCGGGCTACGTGCGCACCGAGTTCCACGC
GCGCGCCGGGATCGACATGTCCAAGTCGCCGTCGTTTCTGTGGCTGCAGGTCGACGACGTGGTCGACCAGAGCCTGGCCG
ACATCGCCCGCGGCAAGGTGATCAGCATTCCGGGCTTGCAGTACAAGGCGATCGTCGCCGCCGAGCGGCTGATCCCGCGC
ACCCTGATGCGGGCGATCACCAAACGAGTCGGTGGTGGCCGTGGCCGAACCTGA

Upstream 100 bases:

>100_bases
CGGGTGGGCGTAACGGCCATCAGGCCACCAACTATCAGCGCTGACGGCGGCCCCGGGCGTCCGCGAGGCCGGGCGCCCCG
CCGTCATTAAGATGTCGCTC

Downstream 100 bases:

>100_bases
GCTCGAGGAGCTGGCCGAGCTGGTGCGCCGGCTGTCGGTGGTGCACGGCCGGGTCACGCTGTCGTCCGGCAAGGAGGCCG
ACTACTACGTCGACCTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPRPVALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLTALAGELRDRAGNIEILPADLGDAADRQRVAERLAAGVRV
LVNNAGFATSGDFWHTDPALLQSQLDVNVTAVMHLTRAALPAMLDAGAGTVINIASIAGLLPGRGSTYSASKAWVISFSE
GLSVGLQGTGVSVHAVCPGYVRTEFHARAGIDMSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAERLIPR
TLMRAITKRVGGGRGRT

Sequences:

>Translated_257_residues
MPRPVALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLTALAGELRDRAGNIEILPADLGDAADRQRVAERLAAGVRV
LVNNAGFATSGDFWHTDPALLQSQLDVNVTAVMHLTRAALPAMLDAGAGTVINIASIAGLLPGRGSTYSASKAWVISFSE
GLSVGLQGTGVSVHAVCPGYVRTEFHARAGIDMSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAERLIPR
TLMRAITKRVGGGRGRT
>Mature_256_residues
PRPVALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLTALAGELRDRAGNIEILPADLGDAADRQRVAERLAAGVRVL
VNNAGFATSGDFWHTDPALLQSQLDVNVTAVMHLTRAALPAMLDAGAGTVINIASIAGLLPGRGSTYSASKAWVISFSEG
LSVGLQGTGVSVHAVCPGYVRTEFHARAGIDMSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAERLIPRT
LMRAITKRVGGGRGRT

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=204, Percent_Identity=32.843137254902, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI7705855, Length=187, Percent_Identity=30.4812834224599, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4557649, Length=218, Percent_Identity=29.3577981651376, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=32.258064516129, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI142976729, Length=260, Percent_Identity=26.9230769230769, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI210032110, Length=242, Percent_Identity=28.5123966942149, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI25282469, Length=257, Percent_Identity=30.7392996108949, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=207, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=27.7486910994764, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=31.6062176165803, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI223718074, Length=200, Percent_Identity=36.5, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI7657478, Length=211, Percent_Identity=32.7014218009479, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723750, Length=214, Percent_Identity=29.4392523364486, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=31.6326530612245, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI186928839, Length=208, Percent_Identity=31.7307692307692, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI210032112, Length=234, Percent_Identity=27.3504273504274, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40807363, Length=201, Percent_Identity=29.3532338308458, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7706318, Length=190, Percent_Identity=28.9473684210526, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=29.3193717277487, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=35.2631578947368, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=190, Percent_Identity=34.7368421052632, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI225579078, Length=266, Percent_Identity=27.8195488721804, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=186, Percent_Identity=34.4086021505376, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1787820, Length=187, Percent_Identity=35.2941176470588, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786701, Length=264, Percent_Identity=28.030303030303, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=28.494623655914, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=30.7392996108949, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789378, Length=215, Percent_Identity=29.7674418604651, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082160, Length=186, Percent_Identity=28.494623655914, Blast_Score=61, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=205, Percent_Identity=36.0975609756098, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71994604, Length=205, Percent_Identity=32.1951219512195, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17508895, Length=258, Percent_Identity=26.3565891472868, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=201, Percent_Identity=26.3681592039801, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=188, Percent_Identity=28.7234042553192, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=199, Percent_Identity=27.6381909547739, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=268, Percent_Identity=27.9850746268657, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=268, Percent_Identity=27.9850746268657, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=209, Percent_Identity=29.6650717703349, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17560176, Length=199, Percent_Identity=26.1306532663317, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI212646214, Length=206, Percent_Identity=25.7281553398058, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558994, Length=212, Percent_Identity=30.6603773584906, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=211, Percent_Identity=28.9099526066351, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=182, Percent_Identity=28.021978021978, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=210, Percent_Identity=29.0476190476191, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=219, Percent_Identity=28.310502283105, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=195, Percent_Identity=25.1282051282051, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=203, Percent_Identity=27.0935960591133, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=33.6734693877551, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319635, Length=185, Percent_Identity=29.1891891891892, Blast_Score=72, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=33.5106382978723, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644339, Length=202, Percent_Identity=34.1584158415842, Blast_Score=97, Evalue=9e-21,
Organism=Drosophila melanogaster, GI23397609, Length=194, Percent_Identity=36.5979381443299, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24584744, Length=190, Percent_Identity=34.2105263157895, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28574402, Length=190, Percent_Identity=34.2105263157895, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=33.1683168316832, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=33.8624338624339, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=33.5078534031414, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21357041, Length=202, Percent_Identity=31.1881188118812, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24584752, Length=233, Percent_Identity=27.0386266094421, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=30.8080808080808, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI116007236, Length=220, Percent_Identity=31.3636363636364, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355319, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24643142, Length=215, Percent_Identity=32.093023255814, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007238, Length=169, Percent_Identity=32.5443786982249, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24581726, Length=131, Percent_Identity=28.2442748091603, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641232, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639444, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27014; Mature: 26883

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPVALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLTALAGELRDRAGNIEILPAD
CCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECC
LGDAADRQRVAERLAAGVRVLVNNAGFATSGDFWHTDPALLQSQLDVNVTAVMHLTRAAL
CCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
PAMLDAGAGTVINIASIAGLLPGRGSTYSASKAWVISFSEGLSVGLQGTGVSVHAVCPGY
HHHHCCCCCCEEEHHHHHHCCCCCCCCCCCCCEEEEEECCCCEECEECCCEEEEEECCCH
VRTEFHARAGIDMSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAERLIPR
HHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHH
TLMRAITKRVGGGRGRT
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRPVALITGPTSGIGAGYARRYASDGYDLVLVARDVDRLTALAGELRDRAGNIEILPAD
CCCEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECC
LGDAADRQRVAERLAAGVRVLVNNAGFATSGDFWHTDPALLQSQLDVNVTAVMHLTRAAL
CCCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
PAMLDAGAGTVINIASIAGLLPGRGSTYSASKAWVISFSEGLSVGLQGTGVSVHAVCPGY
HHHHCCCCCCEEEHHHHHHCCCCCCCCCCCCCEEEEEECCCCEECEECCCEEEEEECCCH
VRTEFHARAGIDMSKSPSFLWLQVDDVVDQSLADIARGKVISIPGLQYKAIVAAERLIPR
HHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHH
TLMRAITKRVGGGRGRT
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]