| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is dnaJ
Identifier: 41409940
GI number: 41409940
Start: 4298156
End: 4299334
Strand: Direct
Name: dnaJ
Synonym: MAP3842
Alternate gene names: 41409940
Gene position: 4298156-4299334 (Clockwise)
Preceding gene: 41409939
Following gene: 41409941
Centisome position: 88.99
GC content: 69.55
Gene sequence:
>1179_bases ATGGCCCAGCGTGAATGGGTCGAAAAAGACTTCTACAAGGAGCTGGGCGTCTCCTCTGACGCCAGTCCCGAAGAGATCAA ACGCGCCTACCGCAAGCTGGCGCGCGATCTACACCCGGATGCCAATCCCGACAATCCCGCCGCCGGCGAACGATTCAAGG CGGTGTCCGAGGCGCACAACGTGTTGTCGGACCCGGCCAAGCGCAAGGAATACGACGAAACCCGAAGGCTTTTCGCCGGA GGCGGTTTCGGCGGGCGCCGGTTCGACACCGGTGGGTTCGGCGGCTTCAACGTCGGCGGGGACGGGGCGGAGTTCAACCT CAACGATTTGTTCGACGCCGCCGGCCGCAGCGGCGGCACCAACATCGGCGACCTGTTCGGCGGCCTGTTCGGGCGCGCTT CGGGCGGCCGGCCCAGCCGGCCGCGCCGCGGCAACGACCTCGAAACCGAGACCCAGCTGGATTTCGTCGAGGCTGCCAAG GGCGTGGCGATGCCGCTGCGGCTGACCAGCCCGGCGCCGTGCACCAACTGCCACGGCAGTGGCGCACGCCCGGGCACCAG CCCCAAGGTGTGCCCCACCTGTAACGGCTCCGGCGTAATCAGCCGCAACCAGGGCGCTTTCGGCTTCTCCGAGCCCTGCA CCGATTGCCGGGGCAGCGGCTCGATCATCGAGCACCCCTGCGACGAGTGCAAGGGCACCGGGGTCACCACCCGCACCCGC ACCATCAACGTGCGGATCCCGCCCGGCGTCGAGGACGGGCAGCGCATCCGGTTGCCCGGTCAGGGCGAGGCCGGGTTGCG CGGCGCGCCGTCGGGCGACCTGTACGTGACGGTACATGTGCGGCCGCACAAGGTGTTCGGCCGCGACGGCGACGACCTGA CCGTGACCGTTCCCGTCAGTTTCACCGAATTGGCTTTGGGCTCAACCATATCGGTGCCCACACTGGACGGCAAGGTCGGG GTTCGGGTGCCCAAGGGCACCGCCGACGGCCGCATCCTGCGGGTGCGCGGACGCGGGGTGCCCAAGCGCAGCGGCGGCCA CGGCGACCTGCTGGTGACGGTAAAGGTCGCGGTGCCACCGAATTTGGACGGCGCCGCTCAGGAGGCGCTGGAGGCCTACG CGGCCGCCGAGCGCGCCAGCGGCTTCGACCCACGGGCGGGATGGGCAGGTAACCGCTGA
Upstream 100 bases:
>100_bases GCCCGAATCGGACGATAACGCCGGCGCATCCGGTGACTAGATCACACAATCAGCACATTGGAAGACAGACCAAGAGAAAG TGGTGAGGGGGTGACGCGGC
Downstream 100 bases:
>100_bases TGGCCAAGAACCGGAAAGGACACGAGTCCCGGACGTTCCTGATCTCGGTGGCCGCCGAGCTGGCCGGCATGCACGCCCAG ACGCTGCGCACCTACGACCG
Product: chaperone protein DnaJ
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 392; Mature: 391
Protein sequence:
>392_residues MAQREWVEKDFYKELGVSSDASPEEIKRAYRKLARDLHPDANPDNPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAG GGFGGRRFDTGGFGGFNVGGDGAEFNLNDLFDAAGRSGGTNIGDLFGGLFGRASGGRPSRPRRGNDLETETQLDFVEAAK GVAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVISRNQGAFGFSEPCTDCRGSGSIIEHPCDECKGTGVTTRTR TINVRIPPGVEDGQRIRLPGQGEAGLRGAPSGDLYVTVHVRPHKVFGRDGDDLTVTVPVSFTELALGSTISVPTLDGKVG VRVPKGTADGRILRVRGRGVPKRSGGHGDLLVTVKVAVPPNLDGAAQEALEAYAAAERASGFDPRAGWAGNR
Sequences:
>Translated_392_residues MAQREWVEKDFYKELGVSSDASPEEIKRAYRKLARDLHPDANPDNPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAG GGFGGRRFDTGGFGGFNVGGDGAEFNLNDLFDAAGRSGGTNIGDLFGGLFGRASGGRPSRPRRGNDLETETQLDFVEAAK GVAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVISRNQGAFGFSEPCTDCRGSGSIIEHPCDECKGTGVTTRTR TINVRIPPGVEDGQRIRLPGQGEAGLRGAPSGDLYVTVHVRPHKVFGRDGDDLTVTVPVSFTELALGSTISVPTLDGKVG VRVPKGTADGRILRVRGRGVPKRSGGHGDLLVTVKVAVPPNLDGAAQEALEAYAAAERASGFDPRAGWAGNR >Mature_391_residues AQREWVEKDFYKELGVSSDASPEEIKRAYRKLARDLHPDANPDNPAAGERFKAVSEAHNVLSDPAKRKEYDETRRLFAGG GFGGRRFDTGGFGGFNVGGDGAEFNLNDLFDAAGRSGGTNIGDLFGGLFGRASGGRPSRPRRGNDLETETQLDFVEAAKG VAMPLRLTSPAPCTNCHGSGARPGTSPKVCPTCNGSGVISRNQGAFGFSEPCTDCRGSGSIIEHPCDECKGTGVTTRTRT INVRIPPGVEDGQRIRLPGQGEAGLRGAPSGDLYVTVHVRPHKVFGRDGDDLTVTVPVSFTELALGSTISVPTLDGKVGV RVPKGTADGRILRVRGRGVPKRSGGHGDLLVTVKVAVPPNLDGAAQEALEAYAAAERASGFDPRAGWAGNR
Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon
COG id: COG0484
COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 J domain [H]
Homologues:
Organism=Homo sapiens, GI205360838, Length=373, Percent_Identity=33.7801608579088, Blast_Score=200, Evalue=2e-51, Organism=Homo sapiens, GI205360840, Length=373, Percent_Identity=33.7801608579088, Blast_Score=199, Evalue=3e-51, Organism=Homo sapiens, GI194328760, Length=364, Percent_Identity=31.8681318681319, Blast_Score=162, Evalue=7e-40, Organism=Homo sapiens, GI194328758, Length=364, Percent_Identity=31.8681318681319, Blast_Score=161, Evalue=9e-40, Organism=Homo sapiens, GI4504511, Length=366, Percent_Identity=29.7814207650273, Blast_Score=146, Evalue=3e-35, Organism=Homo sapiens, GI5031741, Length=363, Percent_Identity=30.8539944903581, Blast_Score=141, Evalue=1e-33, Organism=Homo sapiens, GI7706495, Length=361, Percent_Identity=30.4709141274238, Blast_Score=134, Evalue=1e-31, Organism=Homo sapiens, GI194328762, Length=325, Percent_Identity=28.3076923076923, Blast_Score=117, Evalue=2e-26, Organism=Homo sapiens, GI68077168, Length=79, Percent_Identity=53.1645569620253, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI68077166, Length=79, Percent_Identity=53.1645569620253, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI4885495, Length=65, Percent_Identity=58.4615384615385, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI23503241, Length=64, Percent_Identity=59.375, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI29126218, Length=82, Percent_Identity=46.3414634146341, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI17388799, Length=65, Percent_Identity=58.4615384615385, Blast_Score=76, Evalue=6e-14, Organism=Homo sapiens, GI201862587, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI201862518, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI56549115, Length=65, Percent_Identity=55.3846153846154, Blast_Score=75, Evalue=2e-13, Organism=Homo sapiens, GI45504382, Length=82, Percent_Identity=41.4634146341463, Blast_Score=75, Evalue=2e-13, Organism=Homo sapiens, GI8922563, Length=86, Percent_Identity=39.5348837209302, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI194306642, Length=108, Percent_Identity=42.5925925925926, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI194306640, Length=108, Percent_Identity=42.5925925925926, Blast_Score=72, Evalue=6e-13, Organism=Homo sapiens, GI6631085, Length=65, Percent_Identity=55.3846153846154, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI5453690, Length=64, Percent_Identity=54.6875, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI24308127, Length=66, Percent_Identity=50, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI47777312, Length=82, Percent_Identity=52.4390243902439, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI72534740, Length=66, Percent_Identity=51.5151515151515, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI21553335, Length=65, Percent_Identity=52.3076923076923, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI22749377, Length=65, Percent_Identity=55.3846153846154, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI27151736, Length=123, Percent_Identity=39.0243902439024, Blast_Score=65, Evalue=7e-11, Organism=Homo sapiens, GI56687498, Length=62, Percent_Identity=50, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1786197, Length=368, Percent_Identity=42.3913043478261, Blast_Score=281, Evalue=4e-77, Organism=Escherichia coli, GI1787235, Length=381, Percent_Identity=33.5958005249344, Blast_Score=174, Evalue=9e-45, Organism=Caenorhabditis elegans, GI17553096, Length=373, Percent_Identity=31.9034852546917, Blast_Score=188, Evalue=5e-48, Organism=Caenorhabditis elegans, GI17553098, Length=373, Percent_Identity=31.9034852546917, Blast_Score=187, Evalue=7e-48, Organism=Caenorhabditis elegans, GI17507263, Length=387, Percent_Identity=30.749354005168, Blast_Score=133, Evalue=1e-31, Organism=Caenorhabditis elegans, GI17554644, Length=98, Percent_Identity=47.9591836734694, Blast_Score=82, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17563890, Length=200, Percent_Identity=29.5, Blast_Score=80, Evalue=3e-15, Organism=Caenorhabditis elegans, GI212645553, Length=64, Percent_Identity=54.6875, Blast_Score=79, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17534355, Length=65, Percent_Identity=50.7692307692308, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI115532476, Length=72, Percent_Identity=48.6111111111111, Blast_Score=68, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17543226, Length=64, Percent_Identity=51.5625, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI115532378, Length=94, Percent_Identity=37.2340425531915, Blast_Score=67, Evalue=2e-11, Organism=Saccharomyces cerevisiae, GI6324265, Length=364, Percent_Identity=32.6923076923077, Blast_Score=171, Evalue=2e-43, Organism=Saccharomyces cerevisiae, GI6321094, Length=392, Percent_Identity=32.9081632653061, Blast_Score=145, Evalue=2e-35, Organism=Saccharomyces cerevisiae, GI6323870, Length=366, Percent_Identity=31.6939890710383, Blast_Score=133, Evalue=4e-32, Organism=Saccharomyces cerevisiae, GI6323119, Length=388, Percent_Identity=26.8041237113402, Blast_Score=109, Evalue=7e-25, Organism=Saccharomyces cerevisiae, GI6324252, Length=322, Percent_Identity=24.223602484472, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6322194, Length=79, Percent_Identity=50.6329113924051, Blast_Score=75, Evalue=3e-14, Organism=Saccharomyces cerevisiae, GI6320888, Length=66, Percent_Identity=50, Blast_Score=74, Evalue=5e-14, Organism=Saccharomyces cerevisiae, GI6324321, Length=141, Percent_Identity=30.4964539007092, Blast_Score=67, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6323813, Length=146, Percent_Identity=39.7260273972603, Blast_Score=65, Evalue=2e-11, Organism=Drosophila melanogaster, GI45552813, Length=384, Percent_Identity=33.0729166666667, Blast_Score=185, Evalue=6e-47, Organism=Drosophila melanogaster, GI45549272, Length=384, Percent_Identity=33.0729166666667, Blast_Score=184, Evalue=6e-47, Organism=Drosophila melanogaster, GI45552811, Length=384, Percent_Identity=33.3333333333333, Blast_Score=184, Evalue=1e-46, Organism=Drosophila melanogaster, GI24646562, Length=373, Percent_Identity=29.4906166219839, Blast_Score=129, Evalue=3e-30, Organism=Drosophila melanogaster, GI24646560, Length=373, Percent_Identity=29.4906166219839, Blast_Score=129, Evalue=3e-30, Organism=Drosophila melanogaster, GI24646558, Length=373, Percent_Identity=29.4906166219839, Blast_Score=129, Evalue=3e-30, Organism=Drosophila melanogaster, GI24646556, Length=373, Percent_Identity=29.4906166219839, Blast_Score=129, Evalue=3e-30, Organism=Drosophila melanogaster, GI21357547, Length=373, Percent_Identity=29.4906166219839, Blast_Score=129, Evalue=3e-30, Organism=Drosophila melanogaster, GI19920464, Length=377, Percent_Identity=29.973474801061, Blast_Score=128, Evalue=5e-30, Organism=Drosophila melanogaster, GI20129487, Length=363, Percent_Identity=28.099173553719, Blast_Score=122, Evalue=5e-28, Organism=Drosophila melanogaster, GI24584014, Length=363, Percent_Identity=28.099173553719, Blast_Score=122, Evalue=5e-28, Organism=Drosophila melanogaster, GI28574949, Length=390, Percent_Identity=27.1794871794872, Blast_Score=117, Evalue=1e-26, Organism=Drosophila melanogaster, GI24654066, Length=106, Percent_Identity=43.3962264150943, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24654070, Length=106, Percent_Identity=43.3962264150943, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24654068, Length=106, Percent_Identity=43.3962264150943, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24654072, Length=106, Percent_Identity=43.3962264150943, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24658562, Length=64, Percent_Identity=57.8125, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI24658555, Length=64, Percent_Identity=57.8125, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI161077138, Length=64, Percent_Identity=56.25, Blast_Score=73, Evalue=4e-13, Organism=Drosophila melanogaster, GI24645889, Length=89, Percent_Identity=38.2022471910112, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24641698, Length=131, Percent_Identity=34.3511450381679, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641696, Length=131, Percent_Identity=34.3511450381679, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI17737735, Length=76, Percent_Identity=44.7368421052632, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI28574723, Length=76, Percent_Identity=44.7368421052632, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24668523, Length=76, Percent_Identity=44.7368421052632, Blast_Score=69, Evalue=6e-12, Organism=Drosophila melanogaster, GI21358273, Length=64, Percent_Identity=56.25, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI85726398, Length=65, Percent_Identity=52.3076923076923, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012724 - InterPro: IPR002939 - InterPro: IPR001623 - InterPro: IPR018253 - InterPro: IPR008971 - InterPro: IPR015609 - InterPro: IPR003095 - InterPro: IPR001305 [H]
Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]
EC number: NA
Molecular weight: Translated: 41280; Mature: 41149
Theoretical pI: Translated: 8.40; Mature: 8.40
Prosite motif: PS00636 DNAJ_1 ; PS50076 DNAJ_2 ; PS00637 DNAJ_CXXCXGXG
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 0.5 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 0.3 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAQREWVEKDFYKELGVSSDASPEEIKRAYRKLARDLHPDANPDNPAAGERFKAVSEAHN CCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH VLSDPAKRKEYDETRRLFAGGGFGGRRFDTGGFGGFNVGGDGAEFNLNDLFDAAGRSGGT HHCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC NIGDLFGGLFGRASGGRPSRPRRGNDLETETQLDFVEAAKGVAMPLRLTSPAPCTNCHGS CHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC GARPGTSPKVCPTCNGSGVISRNQGAFGFSEPCTDCRGSGSIIEHPCDECKGTGVTTRTR CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCHHHHCCCCCEEEEE TINVRIPPGVEDGQRIRLPGQGEAGLRGAPSGDLYVTVHVRPHKVFGRDGDDLTVTVPVS EEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEEECHHCCCCCCCCEEEEEECC FTELALGSTISVPTLDGKVGVRVPKGTADGRILRVRGRGVPKRSGGHGDLLVTVKVAVPP HHHHHCCCEECCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECC NLDGAAQEALEAYAAAERASGFDPRAGWAGNR CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC >Mature Secondary Structure AQREWVEKDFYKELGVSSDASPEEIKRAYRKLARDLHPDANPDNPAAGERFKAVSEAHN CCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH VLSDPAKRKEYDETRRLFAGGGFGGRRFDTGGFGGFNVGGDGAEFNLNDLFDAAGRSGGT HHCCHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC NIGDLFGGLFGRASGGRPSRPRRGNDLETETQLDFVEAAKGVAMPLRLTSPAPCTNCHGS CHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCC GARPGTSPKVCPTCNGSGVISRNQGAFGFSEPCTDCRGSGSIIEHPCDECKGTGVTTRTR CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCCHHHHCCCCCEEEEE TINVRIPPGVEDGQRIRLPGQGEAGLRGAPSGDLYVTVHVRPHKVFGRDGDDLTVTVPVS EEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCEEEEEEEECHHCCCCCCCCEEEEEECC FTELALGSTISVPTLDGKVGVRVPKGTADGRILRVRGRGVPKRSGGHGDLLVTVKVAVPP HHHHHCCCEECCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECC NLDGAAQEALEAYAAAERASGFDPRAGWAGNR CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]