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The map label for this gene is eccA3 [H]

Identifier: 41409876

GI number: 41409876

Start: 4221434

End: 4223287

Strand: Direct

Name: eccA3 [H]

Synonym: MAP3778

Alternate gene names: 41409876

Gene position: 4221434-4223287 (Clockwise)

Preceding gene: 41409875

Following gene: 41409877

Centisome position: 87.4

GC content: 67.8

Gene sequence:

>1854_bases
GTGGAACACGGTGACACCGGCATGCTCACAGTTCAGCCGGCCAATTCGCGCGTGGACACGCGCGTTGACGGCGACGTCGT
CAGCCGGTTCGCCACCTGCTGCCGCGCGCTGGGCATCGTCGTCTACCAGCGCCAGCGGCCGGCGGACCTGGCCGCCGCGC
GTTCGGGTTTCGCCGCGCTGACCCGCATCGCCCACGACCAATGCGACGCGTGGACGGGACTGGCGGCCGCCGGAGACACG
TCCCTGCGGGTGCTCGAGGCGGTGTCGCGCACCGCGGCCTCCGCGGGCGTGCTGCAGCGCCAGGTCGACCTGGCACCCAA
CTCGCTGGGCTTCCGCTACGACACCGGACTGTATCTACAGTTCCGCGCGACCACTCCCGACGACTTCCACCTTGCCTACG
CGGCCGCGCTCGCGACGGCGGGACGGTTTGCTGACGCCGACGCGATCGTCGCCGGCCTGACGGCCGAGCGACCGAACTGG
CGTGAGGCCCGCTGGGTGTCCGTCGTCATCAACTACCGCGCCGAGCGCTGGTCGGACGTCGTCAAACTGCTGACCCCGAT
CGTCAACGACACGGACCTGGACGAGGCGTTCTCGCACGCGGCCAAGATCGCGCTCGGCACCGCGCTGGCCCGGCTGGGCA
TGTTCGCCCCGGCGCTGTCCTATCTCGAGGAGCCCGAGGGGCCGGTCGCGGTGGCGGCCGTCGACGGCGCGCTGGCCAAA
GCGCTGGTGCTGCGCGCCCACGTCGACGAGGACTCGGCGAGCGAAGTGCTGCAGGACCTGTACGCGGCCCACCCCGAGAA
CGAACAGGTCGAACAGGCCCTGACCGACACCAGTTTCGGCATCGTGACCACCACGGCGGCGCGCATCGAAGCCCGCACCG
ATCCGTGGGATCCCGAAACCGAGCCCAGCGCCGAGGATTTCGTCGACCCCGCCGCCCACGAACGCAAGGCCGTGCTGCTG
CACGAGGCCGAACGCCAGCTCGCCGAGTTCATCGGCCTCGAAGAGGTCAAGAACCAGGTGTCGCGGCTGAAAAGCTCGGT
CGCCATGGAGCTGGTCCGCAAGCAGCGTGGGCTCGCGGTCGCGCAGCGCGCCCACCACCTGGTCTTCGCCGGCCCGCCCG
GAACCGGTAAGACCACCATCGCCCGCGTGGTCGCCAAGATCTATTGCGGCCTGGGGCTTTTGAAGCGGGAGAACATCCGC
GAGGTGCACCGCGCCGATCTCATCGGCCAGCACATCGGCGAGACCGAGGCCAAGACCAACGCGATCATCGACAGCGCGCT
CGACGGCGTGCTGTTCCTCGACGAGGCCTACGCGCTGGTCGCCACCGGCGCCAAGAACGACTTCGGGCTGGTGGCCATCG
ACACGCTGCTGGCGCGGATGGAGAACGACCGCGACCGCCTGGTGGTCATCATCGCCGGGTACCGGGCCGACCTGGACAAG
TTCCTGGACACCAACGAGGGCTTGCGTTCCCGATTCACCCGCAACATCGACTTCCCTTCCTACGCACCGTCGGAACTGGT
CGAGATCGCGAACAAGATGGCCGAGCAGCGCGACAGCATCTTCGAAAAAGCCGCGCTCGACCACATGGAGGAGTTGTTCA
CGAAGTTGGCAACCGAGTCGACACCCGACGCCAACGGAATTTCGCGACGCAACCTGGACATCGCCGGTAACGGTCGATTC
GTCCGAAACATCGTCGAACGCTCCGAAGAAGAACGAGAGTTCCGGCTCGACCATTCGGAACACGCCGGAACCGGCGAATT
CAGTGACGAGGAGCTGATGACGATCACCGACGACGACGTCGCAAGGTCGGTTGAGCCGCTGCTGCGCGGCCTCGGGCTGT
CGGTGCCGGCATGA

Upstream 100 bases:

>100_bases
GTGAGTCGGACAGGCCCAAACGCCTCGACAGTTAGCTTATGCAATGCTAACTTCAGGCGGGTCAGGTTAGGGGAGACTAC
ATACATGAAAAGACGCGGCC

Downstream 100 bases:

>100_bases
CGTCCAATCAGCAACCCGACGAACGCCGTTCGTTCTCGTCACGCACCCCGGTCAACGACAATCCCGACCAGGTCGAGTAC
CGCCGCGGCTTCGTCACCCG

Product: hypothetical protein

Products: NA

Alternate protein names: ESX conserved component A3; Type VII secretion system protein EccA3; T7SS protein EccA3 [H]

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
MEHGDTGMLTVQPANSRVDTRVDGDVVSRFATCCRALGIVVYQRQRPADLAAARSGFAALTRIAHDQCDAWTGLAAAGDT
SLRVLEAVSRTAASAGVLQRQVDLAPNSLGFRYDTGLYLQFRATTPDDFHLAYAAALATAGRFADADAIVAGLTAERPNW
REARWVSVVINYRAERWSDVVKLLTPIVNDTDLDEAFSHAAKIALGTALARLGMFAPALSYLEEPEGPVAVAAVDGALAK
ALVLRAHVDEDSASEVLQDLYAAHPENEQVEQALTDTSFGIVTTTAARIEARTDPWDPETEPSAEDFVDPAAHERKAVLL
HEAERQLAEFIGLEEVKNQVSRLKSSVAMELVRKQRGLAVAQRAHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIR
EVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDK
FLDTNEGLRSRFTRNIDFPSYAPSELVEIANKMAEQRDSIFEKAALDHMEELFTKLATESTPDANGISRRNLDIAGNGRF
VRNIVERSEEEREFRLDHSEHAGTGEFSDEELMTITDDDVARSVEPLLRGLGLSVPA

Sequences:

>Translated_617_residues
MEHGDTGMLTVQPANSRVDTRVDGDVVSRFATCCRALGIVVYQRQRPADLAAARSGFAALTRIAHDQCDAWTGLAAAGDT
SLRVLEAVSRTAASAGVLQRQVDLAPNSLGFRYDTGLYLQFRATTPDDFHLAYAAALATAGRFADADAIVAGLTAERPNW
REARWVSVVINYRAERWSDVVKLLTPIVNDTDLDEAFSHAAKIALGTALARLGMFAPALSYLEEPEGPVAVAAVDGALAK
ALVLRAHVDEDSASEVLQDLYAAHPENEQVEQALTDTSFGIVTTTAARIEARTDPWDPETEPSAEDFVDPAAHERKAVLL
HEAERQLAEFIGLEEVKNQVSRLKSSVAMELVRKQRGLAVAQRAHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIR
EVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDK
FLDTNEGLRSRFTRNIDFPSYAPSELVEIANKMAEQRDSIFEKAALDHMEELFTKLATESTPDANGISRRNLDIAGNGRF
VRNIVERSEEEREFRLDHSEHAGTGEFSDEELMTITDDDVARSVEPLLRGLGLSVPA
>Mature_617_residues
MEHGDTGMLTVQPANSRVDTRVDGDVVSRFATCCRALGIVVYQRQRPADLAAARSGFAALTRIAHDQCDAWTGLAAAGDT
SLRVLEAVSRTAASAGVLQRQVDLAPNSLGFRYDTGLYLQFRATTPDDFHLAYAAALATAGRFADADAIVAGLTAERPNW
REARWVSVVINYRAERWSDVVKLLTPIVNDTDLDEAFSHAAKIALGTALARLGMFAPALSYLEEPEGPVAVAAVDGALAK
ALVLRAHVDEDSASEVLQDLYAAHPENEQVEQALTDTSFGIVTTTAARIEARTDPWDPETEPSAEDFVDPAAHERKAVLL
HEAERQLAEFIGLEEVKNQVSRLKSSVAMELVRKQRGLAVAQRAHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIR
EVHRADLIGQHIGETEAKTNAIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDK
FLDTNEGLRSRFTRNIDFPSYAPSELVEIANKMAEQRDSIFEKAALDHMEELFTKLATESTPDANGISRRNLDIAGNGRF
VRNIVERSEEEREFRLDHSEHAGTGEFSDEELMTITDDDVARSVEPLLRGLGLSVPA

Specific function: Shows ATPase activity. Could provide energy for export of ESX-3 substrates [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cbxX/cfxQ family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR000641 [H]

Pfam domain/function: PF00004 AAA [H]

EC number: NA

Molecular weight: Translated: 67276; Mature: 67276

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHGDTGMLTVQPANSRVDTRVDGDVVSRFATCCRALGIVVYQRQRPADLAAARSGFAAL
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TRIAHDQCDAWTGLAAAGDTSLRVLEAVSRTAASAGVLQRQVDLAPNSLGFRYDTGLYLQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEE
FRATTPDDFHLAYAAALATAGRFADADAIVAGLTAERPNWREARWVSVVINYRAERWSDV
EEECCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHEEHHHHHHHHHHHHHH
VKLLTPIVNDTDLDEAFSHAAKIALGTALARLGMFAPALSYLEEPEGPVAVAAVDGALAK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHH
ALVLRAHVDEDSASEVLQDLYAAHPENEQVEQALTDTSFGIVTTTAARIEARTDPWDPET
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEHHHHEEECCCCCCCCC
EPSAEDFVDPAAHERKAVLLHEAERQLAEFIGLEEVKNQVSRLKSSVAMELVRKQRGLAV
CCCHHHHCCCCHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AQRAHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTN
HHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDK
HHHHHHHCCCEEHHCHHEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
FLDTNEGLRSRFTRNIDFPSYAPSELVEIANKMAEQRDSIFEKAALDHMEELFTKLATES
HHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPDANGISRRNLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGTGEFSDEELMTITDDDV
CCCCCCCCCCCCEECCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHH
ARSVEPLLRGLGLSVPA
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEHGDTGMLTVQPANSRVDTRVDGDVVSRFATCCRALGIVVYQRQRPADLAAARSGFAAL
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
TRIAHDQCDAWTGLAAAGDTSLRVLEAVSRTAASAGVLQRQVDLAPNSLGFRYDTGLYLQ
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEE
FRATTPDDFHLAYAAALATAGRFADADAIVAGLTAERPNWREARWVSVVINYRAERWSDV
EEECCCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCCHHHEEHHHHHHHHHHHHHH
VKLLTPIVNDTDLDEAFSHAAKIALGTALARLGMFAPALSYLEEPEGPVAVAAVDGALAK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHH
ALVLRAHVDEDSASEVLQDLYAAHPENEQVEQALTDTSFGIVTTTAARIEARTDPWDPET
HHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEHHHHEEECCCCCCCCC
EPSAEDFVDPAAHERKAVLLHEAERQLAEFIGLEEVKNQVSRLKSSVAMELVRKQRGLAV
CCCHHHHCCCCHHCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCHHH
AQRAHHLVFAGPPGTGKTTIARVVAKIYCGLGLLKRENIREVHRADLIGQHIGETEAKTN
HHHCCEEEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AIIDSALDGVLFLDEAYALVATGAKNDFGLVAIDTLLARMENDRDRLVVIIAGYRADLDK
HHHHHHHCCCEEHHCHHEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEECCHHHHHH
FLDTNEGLRSRFTRNIDFPSYAPSELVEIANKMAEQRDSIFEKAALDHMEELFTKLATES
HHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TPDANGISRRNLDIAGNGRFVRNIVERSEEEREFRLDHSEHAGTGEFSDEELMTITDDDV
CCCCCCCCCCCCEECCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHH
ARSVEPLLRGLGLSVPA
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]