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The map label for this gene is fecD [C]

Identifier: 41409824

GI number: 41409824

Start: 4147431

End: 4148459

Strand: Direct

Name: fecD [C]

Synonym: MAP3726

Alternate gene names: 41409824

Gene position: 4147431-4148459 (Clockwise)

Preceding gene: 41409823

Following gene: 41409825

Centisome position: 85.87

GC content: 66.47

Gene sequence:

>1029_bases
TTGACGCTGATCAAGCGGTGTGTCCGCGGGAATGGTTGGCGCACAACGCTGCTGATGCTGTTGCTGCTGACCGCGGTGGC
CGCATCGCTGATGGTGGGGCGCTACCCGGTGGGGGTGGGCGCGATGGCCGGGATGCTGTTTGGTCGTCTTCCTCTGCTGG
ACACTAGCTTTACTCCGGTGGATCAGACGGTGCTGACCCAGATCCGGTTACCGCGCATCGGCTGCGGGGTCTTAGTCGGT
GCGGGGCTGGCGGCCTCGGGTGCGGGCTATCAGACGATGTTCCGCAATCCGCTGGTGTCCCCGGACATTCTGGGGGTGTC
GGCGGGCGCAGGCTTCGGCGGAGCGCTGGCACTGTTACTGCATGCGCCGTACTGGCAGCTAGAAGCGATGGCGTTCGCCA
GCGGATTGCTGGCCGCGGCGTTGGCACTGATCATCGGGCGCGGCATCGGCCGCGATTCGGCGATACTGCTGGTACTGGCC
GGGATGGTGATCGCCAGCGTGTTCGGCGCGTTGATCTCGGTGACCGAATACCTGGCCAACCCCGATGACACCCTGCCGGC
GATCGTGTTCTGGCTGATGGGTGGGCTGGGACGCCAACACCTCGACGGGTTGTTGGCCCCGGCGCTGATCATCGCCGCCG
CGGTCCTGGTGCTCTACGCGTTGCGATGGCCGGTGACGGTGGTGGTATCCGGGGATGAAGACGCACACACCCTCGGCGTC
GACACCCGACGCACCTGGGCTGCGGTGGTAGGCGTCTATACGTTGATCACCGCAACCACAGTGAGCCTGGCCGGCATCGT
GGGCTGGGCAGGCCTGTTGATTCCACATATCGCTCGAGCGTTGGTCGGCCCGGGATTCGGTCGGCTGCTGCTGGTGTCGG
CGGCGCTGGGCGGGGTTTTCGTGGTCGGCGTGGACGACGTGGCACGCGCGGCGGCCAGCGCCGAGATCCCGCTAGGCATC
CTCAGCGCTCTCATCGGGGCGCCGTTCTTCCTGGTGGTGTTGGCCAAGATGCGCCGGCAATGGACGTGA

Upstream 100 bases:

>100_bases
GGGTTTGACCGCGCTGGGCGGCGGCTCGTTCGGTGGCGGCTCGAAGATGCCGATGCTGCCGACCAGCTGGGTCACCAACG
GATCAGGCGAGGCCTAGCGG

Downstream 100 bases:

>100_bases
GCAGCGCGGCGATCGCCGCCGAACAGCTGTCATTCGGCTACCCCGGCGACGGACAGCGGCTGATCGCGGTGTCGCTGGCG
GTGCAGCCGGGCCAGGTGTG

Product: hypothetical protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTLIKRCVRGNGWRTTLLMLLLLTAVAASLMVGRYPVGVGAMAGMLFGRLPLLDTSFTPVDQTVLTQIRLPRIGCGVLVG
AGLAASGAGYQTMFRNPLVSPDILGVSAGAGFGGALALLLHAPYWQLEAMAFASGLLAAALALIIGRGIGRDSAILLVLA
GMVIASVFGALISVTEYLANPDDTLPAIVFWLMGGLGRQHLDGLLAPALIIAAAVLVLYALRWPVTVVVSGDEDAHTLGV
DTRRTWAAVVGVYTLITATTVSLAGIVGWAGLLIPHIARALVGPGFGRLLLVSAALGGVFVVGVDDVARAAASAEIPLGI
LSALIGAPFFLVVLAKMRRQWT

Sequences:

>Translated_342_residues
MTLIKRCVRGNGWRTTLLMLLLLTAVAASLMVGRYPVGVGAMAGMLFGRLPLLDTSFTPVDQTVLTQIRLPRIGCGVLVG
AGLAASGAGYQTMFRNPLVSPDILGVSAGAGFGGALALLLHAPYWQLEAMAFASGLLAAALALIIGRGIGRDSAILLVLA
GMVIASVFGALISVTEYLANPDDTLPAIVFWLMGGLGRQHLDGLLAPALIIAAAVLVLYALRWPVTVVVSGDEDAHTLGV
DTRRTWAAVVGVYTLITATTVSLAGIVGWAGLLIPHIARALVGPGFGRLLLVSAALGGVFVVGVDDVARAAASAEIPLGI
LSALIGAPFFLVVLAKMRRQWT
>Mature_341_residues
TLIKRCVRGNGWRTTLLMLLLLTAVAASLMVGRYPVGVGAMAGMLFGRLPLLDTSFTPVDQTVLTQIRLPRIGCGVLVGA
GLAASGAGYQTMFRNPLVSPDILGVSAGAGFGGALALLLHAPYWQLEAMAFASGLLAAALALIIGRGIGRDSAILLVLAG
MVIASVFGALISVTEYLANPDDTLPAIVFWLMGGLGRQHLDGLLAPALIIAAAVLVLYALRWPVTVVVSGDEDAHTLGVD
TRRTWAAVVGVYTLITATTVSLAGIVGWAGLLIPHIARALVGPGFGRLLLVSAALGGVFVVGVDDVARAAASAEIPLGIL
SALIGAPFFLVVLAKMRRQWT

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=283, Percent_Identity=36.3957597173145, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788004, Length=293, Percent_Identity=36.8600682593857, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790741, Length=299, Percent_Identity=31.7725752508361, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786805, Length=285, Percent_Identity=32.9824561403509, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=32.5088339222615, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786804, Length=290, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35320; Mature: 35188

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIKRCVRGNGWRTTLLMLLLLTAVAASLMVGRYPVGVGAMAGMLFGRLPLLDTSFTPV
CHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCH
DQTVLTQIRLPRIGCGVLVGAGLAASGAGYQTMFRNPLVSPDILGVSAGAGFGGALALLL
HHHHHHHHCCCCCCHHHHHHCCHHCCCCCHHHHHCCCCCCCCCEEECCCCCHHHHHHHHH
HAPYWQLEAMAFASGLLAAALALIIGRGIGRDSAILLVLAGMVIASVFGALISVTEYLAN
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDDTLPAIVFWLMGGLGRQHLDGLLAPALIIAAAVLVLYALRWPVTVVVSGDEDAHTLGV
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
DTRRTWAAVVGVYTLITATTVSLAGIVGWAGLLIPHIARALVGPGFGRLLLVSAALGGVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEE
VVGVDDVARAAASAEIPLGILSALIGAPFFLVVLAKMRRQWT
EEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLIKRCVRGNGWRTTLLMLLLLTAVAASLMVGRYPVGVGAMAGMLFGRLPLLDTSFTPV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCH
DQTVLTQIRLPRIGCGVLVGAGLAASGAGYQTMFRNPLVSPDILGVSAGAGFGGALALLL
HHHHHHHHCCCCCCHHHHHHCCHHCCCCCHHHHHCCCCCCCCCEEECCCCCHHHHHHHHH
HAPYWQLEAMAFASGLLAAALALIIGRGIGRDSAILLVLAGMVIASVFGALISVTEYLAN
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDDTLPAIVFWLMGGLGRQHLDGLLAPALIIAAAVLVLYALRWPVTVVVSGDEDAHTLGV
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCC
DTRRTWAAVVGVYTLITATTVSLAGIVGWAGLLIPHIARALVGPGFGRLLLVSAALGGVF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCEE
VVGVDDVARAAASAEIPLGILSALIGAPFFLVVLAKMRRQWT
EEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]