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The map label for this gene is narU

Identifier: 41409810

GI number: 41409810

Start: 4128804

End: 4130195

Strand: Direct

Name: narU

Synonym: MAP3712

Alternate gene names: 41409810

Gene position: 4128804-4130195 (Clockwise)

Preceding gene: 41409801

Following gene: 41409812

Centisome position: 85.49

GC content: 69.04

Gene sequence:

>1392_bases
ATGACCACGACCATCACCCCGGTACCGCAGCCCGCGGCGGCGCCCGAGCGGCACAAGGGGCGGCACTGGATCGACGACTG
GCGGCCCGAAGACCCCGAATTCTGGGAGACGACGGGCAAGGCGATCGCCCGCCGCAACCTGATCTTCTCGATCTTCGCCG
AACACGTCGGGTTCAGCGTGTGGATGCTGTGGAGCATCGTGGTGGTGCACATGACGGCCGGACCGCACGGGCACCCGTCG
GCGTCCGGGTGGGCGCTGACCGCCAGCCAGGCGCTGTGCCTGGTCGCCGTGCCCAGCGGGGTCGGCGCCTTCCTGCGGCT
GCCCTACACGTTCGCCGTCCCGGTGTTCGGCGGCCGCAACTGGACGACCATCTCGGCAGCCTTGCTGCTGATCCCGTGCC
TGCTGCTGGCGTGGGCGGTGAGCCATCCCGGCATCCCGTTCGGGGTGCTGGTGGCGATCGCCGCGACCGCCGGGTTCGGC
GGCGGCAACTTCGCCTCGTCGATGGCCAACATCTCCTTCTTCTACCCGGAGAAGGACAAGGGCTGGGCGCTGGGGCTCAA
CGCGGCCGGCGGCAACATCGGCGTGGCGATGGTGCAGAAGGTCATCCCGCCCGTCGTGATCGCGGGCGGCGGCGTGGCGC
TGTCCCGGGCCGGGCTGTTCTACGTGCCGCTGGCGGTCGTGGCTGCGGTGTGCGCGTTCCTGTTCATGAACAACCTGACC
GAGATCAAGGCCGACGTGAAGCCGGTGTGGCAGTCGCTGCGCCACGCCGACACCTGGATCATGTCGCTGCTCTACATCGG
CACCTTCGGATCCTTCATCGGCTACTCGGCCGCCTTCCCGACCCTGCTCAAAACGGTGTTCGGGCGCGGCGACATCGCGC
TGGCGTGGGCGTTTCTGGGCGCCGCCATCGGGTCGGTGATCCGGCCGCTGGGCGGCAAGCTGGCCGACCGGGTCGGCGGG
GCGCGGATCACCGCGGCCAGCTTTGTGATGCTGGCCGTCGGCGCGGCGGCCGCGCTGTGGTCGGTGAAGGCGGTGAACCT
GCCGGCCTTCTTCGCCAGCTTCATGTTCCTGTTCGTTGCGACCGGCATCGGCAACGGTTCGACCTACCGGATGATCTCGC
GGATCTTCAAGATCAAGGGCGAGCTGGCCGGGGGCGATCCCGACACCATGGTGACGATGCGCCGCCAGGCCGCCGGCGCG
CTGGGCGTCATCTCGGCGGTGGGCGCCTTCGGCGGGTTCATCGTGCCGCTGGCCTACGCCTGGTCGAAGTCGCAGTTCGG
CAGCATCGAACCCGCGCTGCGCTTCTATGTGGTGTTCTTCCTGGGCTTGCTGGCCGTCACCTGGTACTGCTACCTGCGCA
AGCACAACGCGATCACCCGGGTCGGCATCTAG

Upstream 100 bases:

>100_bases
GGGCGCCCTGATGAGACCCGCGCCCGGCGAGAGACGGGCGCCCTGATGAGACCCGCGCCCGGTGAAACGGGCGCCCTATG
AGACAGGGGAGACCCACCGG

Downstream 100 bases:

>100_bases
CCCCAGGACGGTTTCTGCCGGCCGCCGTATCCCTGCCAGGGGGAGTAGTCGGCGATCAGCTCCTCCTGCGGTGGGCGCTG
GTCCTCGGGGATGTGCTGCA

Product: NarU

Products: NA

Alternate protein names: Nitrite facilitator 1 [H]

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MTTTITPVPQPAAAPERHKGRHWIDDWRPEDPEFWETTGKAIARRNLIFSIFAEHVGFSVWMLWSIVVVHMTAGPHGHPS
ASGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGRNWTTISAALLLIPCLLLAWAVSHPGIPFGVLVAIAATAGFG
GGNFASSMANISFFYPEKDKGWALGLNAAGGNIGVAMVQKVIPPVVIAGGGVALSRAGLFYVPLAVVAAVCAFLFMNNLT
EIKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPTLLKTVFGRGDIALAWAFLGAAIGSVIRPLGGKLADRVGG
ARITAASFVMLAVGAAAALWSVKAVNLPAFFASFMFLFVATGIGNGSTYRMISRIFKIKGELAGGDPDTMVTMRRQAAGA
LGVISAVGAFGGFIVPLAYAWSKSQFGSIEPALRFYVVFFLGLLAVTWYCYLRKHNAITRVGI

Sequences:

>Translated_463_residues
MTTTITPVPQPAAAPERHKGRHWIDDWRPEDPEFWETTGKAIARRNLIFSIFAEHVGFSVWMLWSIVVVHMTAGPHGHPS
ASGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGRNWTTISAALLLIPCLLLAWAVSHPGIPFGVLVAIAATAGFG
GGNFASSMANISFFYPEKDKGWALGLNAAGGNIGVAMVQKVIPPVVIAGGGVALSRAGLFYVPLAVVAAVCAFLFMNNLT
EIKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPTLLKTVFGRGDIALAWAFLGAAIGSVIRPLGGKLADRVGG
ARITAASFVMLAVGAAAALWSVKAVNLPAFFASFMFLFVATGIGNGSTYRMISRIFKIKGELAGGDPDTMVTMRRQAAGA
LGVISAVGAFGGFIVPLAYAWSKSQFGSIEPALRFYVVFFLGLLAVTWYCYLRKHNAITRVGI
>Mature_462_residues
TTTITPVPQPAAAPERHKGRHWIDDWRPEDPEFWETTGKAIARRNLIFSIFAEHVGFSVWMLWSIVVVHMTAGPHGHPSA
SGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGRNWTTISAALLLIPCLLLAWAVSHPGIPFGVLVAIAATAGFGG
GNFASSMANISFFYPEKDKGWALGLNAAGGNIGVAMVQKVIPPVVIAGGGVALSRAGLFYVPLAVVAAVCAFLFMNNLTE
IKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPTLLKTVFGRGDIALAWAFLGAAIGSVIRPLGGKLADRVGGA
RITAASFVMLAVGAAAALWSVKAVNLPAFFASFMFLFVATGIGNGSTYRMISRIFKIKGELAGGDPDTMVTMRRQAAGAL
GVISAVGAFGGFIVPLAYAWSKSQFGSIEPALRFYVVFFLGLLAVTWYCYLRKHNAITRVGI

Specific function: Involved in excretion of nitrite produced by the dissimilatory reduction of nitrate [H]

COG id: COG2223

COG function: function code P; Nitrate/nitrite transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family [H]

Homologues:

Organism=Escherichia coli, GI1787475, Length=470, Percent_Identity=41.063829787234, Blast_Score=302, Evalue=4e-83,
Organism=Escherichia coli, GI1787743, Length=469, Percent_Identity=39.6588486140725, Blast_Score=291, Evalue=7e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004737 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49149; Mature: 49018

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTITPVPQPAAAPERHKGRHWIDDWRPEDPEFWETTGKAIARRNLIFSIFAEHVGFSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMLWSIVVVHMTAGPHGHPSASGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGRN
HHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHCCCCCEEEECCCCCC
WTTISAALLLIPCLLLAWAVSHPGIPFGVLVAIAATAGFGGGNFASSMANISFFYPEKDK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCEEEECCCCCC
GWALGLNAAGGNIGVAMVQKVIPPVVIAGGGVALSRAGLFYVPLAVVAAVCAFLFMNNLT
CEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHCHH
EIKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPTLLKTVFGRGDIALAWAFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAIGSVIRPLGGKLADRVGGARITAASFVMLAVGAAAALWSVKAVNLPAFFASFMFLFVA
HHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TGIGNGSTYRMISRIFKIKGELAGGDPDTMVTMRRQAAGALGVISAVGAFGGFIVPLAYA
HCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
WSKSQFGSIEPALRFYVVFFLGLLAVTWYCYLRKHNAITRVGI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
TTTITPVPQPAAAPERHKGRHWIDDWRPEDPEFWETTGKAIARRNLIFSIFAEHVGFSV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WMLWSIVVVHMTAGPHGHPSASGWALTASQALCLVAVPSGVGAFLRLPYTFAVPVFGGRN
HHHHHHHHHHCCCCCCCCCCCCCCEEECCCCEEEEECCCCCCHHHCCCCCEEEECCCCCC
WTTISAALLLIPCLLLAWAVSHPGIPFGVLVAIAATAGFGGGNFASSMANISFFYPEKDK
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCEEEECCCCCC
GWALGLNAAGGNIGVAMVQKVIPPVVIAGGGVALSRAGLFYVPLAVVAAVCAFLFMNNLT
CEEEEEECCCCCHHHHHHHHHCCCEEEECCCHHHHCCCHHHHHHHHHHHHHHHHHHHCHH
EIKADVKPVWQSLRHADTWIMSLLYIGTFGSFIGYSAAFPTLLKTVFGRGDIALAWAFLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AAIGSVIRPLGGKLADRVGGARITAASFVMLAVGAAAALWSVKAVNLPAFFASFMFLFVA
HHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TGIGNGSTYRMISRIFKIKGELAGGDPDTMVTMRRQAAGALGVISAVGAFGGFIVPLAYA
HCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
WSKSQFGSIEPALRFYVVFFLGLLAVTWYCYLRKHNAITRVGI
HCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2668029; 8905232; 9278503; 2657652 [H]