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The map label for this gene is yyaE [H]

Identifier: 41409734

GI number: 41409734

Start: 4032148

End: 4034748

Strand: Direct

Name: yyaE [H]

Synonym: MAP3636

Alternate gene names: 41409734

Gene position: 4032148-4034748 (Clockwise)

Preceding gene: 41409733

Following gene: 41409736

Centisome position: 83.49

GC content: 70.36

Gene sequence:

>2601_bases
ATGACCGGTGAATGGCAACCGAGCGCCTGCATCCTCTGCGAATGCAACTGCGGCATCGTCGTCCAAGTGGAAGACCGCCG
GCTGGCCCGCATCCGCGGCGACAAGGCGCACCCCGCCTCGCAGGGCTACACCTGCAACAAGGCGCTGCGGCTGGACCACT
ACCAGAACAGCCGCGCCCGGTTGACCTCGCCGCTGCGCCGCCGCCCCGACGGCAGCTACGAGGAGATCGACTGGGACACC
GCGATCGTCGAGATCGCCGAGGGGTTCAAGCGCATTCGCGACAGCTACGGCGGCGACAAGATCTTCTACTACGGCGGCGG
CGGGCAGGGCAACCACCTGGGCGGGGCCTACAGCGGCGCCTTCCTGAAGGCGCTGGGCTCGCGCTACCGGTCGAATGCGT
TGGCGCAGGAGAAAACCGGGGAGTCCTGGATCGACGGCCAGCTGTACGGCGGTCACACCCGCGGCGAGTTCGAGCACGCC
GAGGTCGCGGTGTTCGTCGGGAAGAATCCGTGGATGTCGCAAAGCTTTCCACGCGCCCGGGTGGTGCTCAACGAGATCGC
GAAGGATCCGGCGCGGTCGATGATCGTCATCGATCCCGTCGTCACCGACACGGCCAAGATGGCCGACTTCCACCTGCGGG
TGCGTCCCGGCACCGACGCGTGGTGCCTGGCCGCGCTGGCCGCGGTCCTCGTCCAGGAAAACCTGTGCGACGAGGCATTT
CTCGCCGAGCACGTGCGCGGCGCCGACGGCGTCCGGCGGGCGTTGCGTGACGTGGCGGTGTGCGAGTGCGCGGCGCACTG
CGGGGTGGACGAGGAGCTGCTGCGCACCGCGGCGCGGCGCATCGGCACCGCGGACAGCGTGGCGGTGTTCGAGGATCTCG
GCGTGCAGCAGGCGCCCAACAGCACGCTGTGCTCCTACCTGAATAAGCTGCTGTGGATCCTGACCGGGAACTTCGCGAAA
CGCGGTGGCCAGCATCTGCATTCGTCGTTCGCGCCGCTGTTCGGCCAGTTCTCCGGGCGCACGCCGGTGACCGGCGCGCC
CATCATCTCCGGCCTGGTGCCGTCGAACGTGGTGCCCGAGGAGATCCTGACCGATCACCCGGACCGGTTCCGGGCCATGA
TCGTGGAGAGCAGCAATCCCGCGCACTCGCTGGCCAATTCGGCGGCGTGCCGGGAGGCCTTCGCGTCGCTGGAACTGATG
GTGGTCATCGACGTGGCGATGACCGAGACGGCCCGGCTGGCGCATTATGTGCTGCCGGCCGCCTCCCAGTTCGAGAAGCC
CGAGGCCACCTTCTTCAACCTGGAGTTCCCGCGCAACACCTTTCAGCTGCGCCGCCCGCTGCTGACGCCGCTGCCGGGCA
CGCTGCCGGAACCCGAGATCTGGGCCCGGCTGGTGCGGGCGCTCGGCGTGGTGACGGAGGCGGATCTGCGGCCGCTGCAC
GACGCCGCGCGGCGCGGCCGGCACGCCTACACCGAAGCGTTCTTGACCGCTGTGTCCACCAATCCGACTGTGGCGCAGCT
ACTTCCGTTTGTGCTGTACGAAACGCTGGGGCCCACCCTGCCGGACGGACTGCGTGGCGCCGCCGCGCTGTGGGGCCTGG
CCCAAAAGACCGCGCTGACCTATCGGGAGGCGGTGCGCCGCGCCGGTCACGCCGACGGCAACGCGCTGTTCGACGCCATC
CTGGACAACCCGTCGGGGGTGACGTTCACCGTGCACGACTACGCGGACGACTTCACCCTGATCGGCCATCCCGACCACAA
GATTGCGCTCGAAATCCCGGCGATGCTGCAGGAATTGGCGAAGCTGTCGAGCGGCCCGCCGCGGCTGACCACCGAAGAGT
TCCCGATCGTGCTGTCGGTGGGGGAGCGGCGCGCCTATACCGCCAACGACATCTTCCGCGACCCGTCCTGGCGCAAACGC
GATGCCGAGGGCGCGCTGCGGGTCAGCGTCGAAGACGCCCAGGCCCTCGGGCTGGCCGACGGGTGCCGCGCCCGGATCAG
CACCGCGGCGGGCAGCGCCGAGGCCACCGTCGAGATCAGCGAGACCATGCTGGCCGGTCATGCCGCGTTGCCCAACGGTT
TTGGGCTGGACTACATCGGCGACGACGGGCGCACCGTCGTTCCCGGGGTGGCGCCGAACGCGCAGCCGCACGTGGCGGGC
CACCTCGGCGCGCTCGTTGGCCTCCAGGTGGGCGCGGGCACGCTCGAGTACCTCCCACAGCGCCTTGGCGATGCCATAGG
GCCGGGTGCCGTCGAGCACCTCTTCGACCTGGCGCGCGGTGCGCCCGTAGGGGTCGCGCTTCAGCGCGCCGGCGATGCGC
TTCCAGGTGGCGATGTCACCGCTCTGCAGAGCCGAACGGATGGCGGCGGTCGGCCAGAATTCCACCGGCTGGTCGAGGTC
CGGCAGCGGGGCGGACGGGCCGCCGCCGCGGTTGCGCTGGTCCCCCGGGGCCGGCCGGTGCGGCGGCGAAGCCGGGCGTC
GGTCGGGTGCCAACGTCACCTCGCCTCCTCCAGCATCGCGACGGCCACGGCCAGGCAGCGCTGCCTGATCTGCTCCCAGT
CCGCGGGTGCGTCGGCGTCCGGCCCCTGGTCATCCGGGTAA

Upstream 100 bases:

>100_bases
CGCCGCGACCCGGCACCCCTGGACGTCGTGCACCGCCAACTGCGCGACCTGCTGGCCGCAGAACTTGCGGGCGAAACCGC
CGCAGGAAGGAAATCCCGAC

Downstream 100 bases:

>100_bases
TCGCACGGATCGGGATCGGCGAGCCGGCGGACCAACTGGGTGGCGATCCATTGCCGCCTGGATGATTCACAACAGTAATA
CCTGTCCATTCCGGCCAGCA

Product: hypothetical protein

Products: nitrate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 866; Mature: 865

Protein sequence:

>866_residues
MTGEWQPSACILCECNCGIVVQVEDRRLARIRGDKAHPASQGYTCNKALRLDHYQNSRARLTSPLRRRPDGSYEEIDWDT
AIVEIAEGFKRIRDSYGGDKIFYYGGGGQGNHLGGAYSGAFLKALGSRYRSNALAQEKTGESWIDGQLYGGHTRGEFEHA
EVAVFVGKNPWMSQSFPRARVVLNEIAKDPARSMIVIDPVVTDTAKMADFHLRVRPGTDAWCLAALAAVLVQENLCDEAF
LAEHVRGADGVRRALRDVAVCECAAHCGVDEELLRTAARRIGTADSVAVFEDLGVQQAPNSTLCSYLNKLLWILTGNFAK
RGGQHLHSSFAPLFGQFSGRTPVTGAPIISGLVPSNVVPEEILTDHPDRFRAMIVESSNPAHSLANSAACREAFASLELM
VVIDVAMTETARLAHYVLPAASQFEKPEATFFNLEFPRNTFQLRRPLLTPLPGTLPEPEIWARLVRALGVVTEADLRPLH
DAARRGRHAYTEAFLTAVSTNPTVAQLLPFVLYETLGPTLPDGLRGAAALWGLAQKTALTYREAVRRAGHADGNALFDAI
LDNPSGVTFTVHDYADDFTLIGHPDHKIALEIPAMLQELAKLSSGPPRLTTEEFPIVLSVGERRAYTANDIFRDPSWRKR
DAEGALRVSVEDAQALGLADGCRARISTAAGSAEATVEISETMLAGHAALPNGFGLDYIGDDGRTVVPGVAPNAQPHVAG
HLGALVGLQVGAGTLEYLPQRLGDAIGPGAVEHLFDLARGAPVGVALQRAGDALPGGDVTALQSRTDGGGRPEFHRLVEV
RQRGGRAAAAVALVPRGRPVRRRSRASVGCQRHLASSSIATATARQRCLICSQSAGASASGPWSSG

Sequences:

>Translated_866_residues
MTGEWQPSACILCECNCGIVVQVEDRRLARIRGDKAHPASQGYTCNKALRLDHYQNSRARLTSPLRRRPDGSYEEIDWDT
AIVEIAEGFKRIRDSYGGDKIFYYGGGGQGNHLGGAYSGAFLKALGSRYRSNALAQEKTGESWIDGQLYGGHTRGEFEHA
EVAVFVGKNPWMSQSFPRARVVLNEIAKDPARSMIVIDPVVTDTAKMADFHLRVRPGTDAWCLAALAAVLVQENLCDEAF
LAEHVRGADGVRRALRDVAVCECAAHCGVDEELLRTAARRIGTADSVAVFEDLGVQQAPNSTLCSYLNKLLWILTGNFAK
RGGQHLHSSFAPLFGQFSGRTPVTGAPIISGLVPSNVVPEEILTDHPDRFRAMIVESSNPAHSLANSAACREAFASLELM
VVIDVAMTETARLAHYVLPAASQFEKPEATFFNLEFPRNTFQLRRPLLTPLPGTLPEPEIWARLVRALGVVTEADLRPLH
DAARRGRHAYTEAFLTAVSTNPTVAQLLPFVLYETLGPTLPDGLRGAAALWGLAQKTALTYREAVRRAGHADGNALFDAI
LDNPSGVTFTVHDYADDFTLIGHPDHKIALEIPAMLQELAKLSSGPPRLTTEEFPIVLSVGERRAYTANDIFRDPSWRKR
DAEGALRVSVEDAQALGLADGCRARISTAAGSAEATVEISETMLAGHAALPNGFGLDYIGDDGRTVVPGVAPNAQPHVAG
HLGALVGLQVGAGTLEYLPQRLGDAIGPGAVEHLFDLARGAPVGVALQRAGDALPGGDVTALQSRTDGGGRPEFHRLVEV
RQRGGRAAAAVALVPRGRPVRRRSRASVGCQRHLASSSIATATARQRCLICSQSAGASASGPWSSG
>Mature_865_residues
TGEWQPSACILCECNCGIVVQVEDRRLARIRGDKAHPASQGYTCNKALRLDHYQNSRARLTSPLRRRPDGSYEEIDWDTA
IVEIAEGFKRIRDSYGGDKIFYYGGGGQGNHLGGAYSGAFLKALGSRYRSNALAQEKTGESWIDGQLYGGHTRGEFEHAE
VAVFVGKNPWMSQSFPRARVVLNEIAKDPARSMIVIDPVVTDTAKMADFHLRVRPGTDAWCLAALAAVLVQENLCDEAFL
AEHVRGADGVRRALRDVAVCECAAHCGVDEELLRTAARRIGTADSVAVFEDLGVQQAPNSTLCSYLNKLLWILTGNFAKR
GGQHLHSSFAPLFGQFSGRTPVTGAPIISGLVPSNVVPEEILTDHPDRFRAMIVESSNPAHSLANSAACREAFASLELMV
VIDVAMTETARLAHYVLPAASQFEKPEATFFNLEFPRNTFQLRRPLLTPLPGTLPEPEIWARLVRALGVVTEADLRPLHD
AARRGRHAYTEAFLTAVSTNPTVAQLLPFVLYETLGPTLPDGLRGAAALWGLAQKTALTYREAVRRAGHADGNALFDAIL
DNPSGVTFTVHDYADDFTLIGHPDHKIALEIPAMLQELAKLSSGPPRLTTEEFPIVLSVGERRAYTANDIFRDPSWRKRD
AEGALRVSVEDAQALGLADGCRARISTAAGSAEATVEISETMLAGHAALPNGFGLDYIGDDGRTVVPGVAPNAQPHVAGH
LGALVGLQVGAGTLEYLPQRLGDAIGPGAVEHLFDLARGAPVGVALQRAGDALPGGDVTALQSRTDGGGRPEFHRLVEVR
QRGGRAAAAVALVPRGRPVRRRSRASVGCQRHLASSSIATATARQRCLICSQSAGASASGPWSSG

Specific function: Decomposes Formic Acid To Hydrogen And Carbon Dioxide Under Anaerobic Conditions In The Absence Of Exogenous Electron Acceptors. [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=463, Percent_Identity=26.5658747300216, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1787870, Length=483, Percent_Identity=25.879917184265, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI171474008, Length=355, Percent_Identity=27.6056338028169, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI87081797, Length=489, Percent_Identity=25.3578732106339, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI1788534, Length=281, Percent_Identity=25.2669039145907, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI3868719, Length=294, Percent_Identity=26.530612244898, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI3868720, Length=294, Percent_Identity=25.1700680272109, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.99.4

Molecular weight: Translated: 92990; Mature: 92859

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGEWQPSACILCECNCGIVVQVEDRRLARIRGDKAHPASQGYTCNKALRLDHYQNSRAR
CCCCCCCCEEEEEECCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCHHH
LTSPLRRRPDGSYEEIDWDTAIVEIAEGFKRIRDSYGGDKIFYYGGGGQGNHLGGAYSGA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHH
FLKALGSRYRSNALAQEKTGESWIDGQLYGGHTRGEFEHAEVAVFVGKNPWMSQSFPRAR
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHH
VVLNEIAKDPARSMIVIDPVVTDTAKMADFHLRVRPGTDAWCLAALAAVLVQENLCDEAF
HHHHHHHCCCCCCEEEECCCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHH
LAEHVRGADGVRRALRDVAVCECAAHCGVDEELLRTAARRIGTADSVAVFEDLGVQQAPN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
STLCSYLNKLLWILTGNFAKRGGQHLHSSFAPLFGQFSGRTPVTGAPIISGLVPSNVVPE
HHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCH
EILTDHPDRFRAMIVESSNPAHSLANSAACREAFASLELMVVIDVAMTETARLAHYVLPA
HHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHCCC
ASQFEKPEATFFNLEFPRNTFQLRRPLLTPLPGTLPEPEIWARLVRALGVVTEADLRPLH
HHHCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
DAARRGRHAYTEAFLTAVSTNPTVAQLLPFVLYETLGPTLPDGLRGAAALWGLAQKTALT
HHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
YREAVRRAGHADGNALFDAILDNPSGVTFTVHDYADDFTLIGHPDHKIALEIPAMLQELA
HHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEEEHHHHHHHHH
KLSSGPPRLTTEEFPIVLSVGERRAYTANDIFRDPSWRKRDAEGALRVSVEDAQALGLAD
HHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCCCCCCCEEEEEECHHHHHCCCH
GCRARISTAAGSAEATVEISETMLAGHAALPNGFGLDYIGDDGRTVVPGVAPNAQPHVAG
HHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCCCCEECCCCCEECCCCCCCCCCCHHH
HLGALVGLQVGAGTLEYLPQRLGDAIGPGAVEHLFDLARGAPVGVALQRAGDALPGGDVT
HHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEE
ALQSRTDGGGRPEFHRLVEVRQRGGRAAAAVALVPRGRPVRRRSRASVGCQRHLASSSIA
EEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
TATARQRCLICSQSAGASASGPWSSG
HHHHHHHEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TGEWQPSACILCECNCGIVVQVEDRRLARIRGDKAHPASQGYTCNKALRLDHYQNSRAR
CCCCCCCEEEEEECCCCEEEEECCCHHHHHCCCCCCCCCCCCCCCHHHCCCCCCCCHHH
LTSPLRRRPDGSYEEIDWDTAIVEIAEGFKRIRDSYGGDKIFYYGGGGQGNHLGGAYSGA
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHH
FLKALGSRYRSNALAQEKTGESWIDGQLYGGHTRGEFEHAEVAVFVGKNPWMSQSFPRAR
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCCCCCHHH
VVLNEIAKDPARSMIVIDPVVTDTAKMADFHLRVRPGTDAWCLAALAAVLVQENLCDEAF
HHHHHHHCCCCCCEEEECCCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHHHHHCCHHHH
LAEHVRGADGVRRALRDVAVCECAAHCGVDEELLRTAARRIGTADSVAVFEDLGVQQAPN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHCCCCCCCC
STLCSYLNKLLWILTGNFAKRGGQHLHSSFAPLFGQFSGRTPVTGAPIISGLVPSNVVPE
HHHHHHHHHHHHHHCCCHHHHCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCH
EILTDHPDRFRAMIVESSNPAHSLANSAACREAFASLELMVVIDVAMTETARLAHYVLPA
HHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHCCC
ASQFEKPEATFFNLEFPRNTFQLRRPLLTPLPGTLPEPEIWARLVRALGVVTEADLRPLH
HHHCCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
DAARRGRHAYTEAFLTAVSTNPTVAQLLPFVLYETLGPTLPDGLRGAAALWGLAQKTALT
HHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
YREAVRRAGHADGNALFDAILDNPSGVTFTVHDYADDFTLIGHPDHKIALEIPAMLQELA
HHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEECCCCCEEEECCCCCEEEEEHHHHHHHHH
KLSSGPPRLTTEEFPIVLSVGERRAYTANDIFRDPSWRKRDAEGALRVSVEDAQALGLAD
HHCCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCCCCCCCCCCEEEEEECHHHHHCCCH
GCRARISTAAGSAEATVEISETMLAGHAALPNGFGLDYIGDDGRTVVPGVAPNAQPHVAG
HHHHHHHHCCCCCCEEEEEHHHHHHCCCCCCCCCCCCEECCCCCEECCCCCCCCCCCHHH
HLGALVGLQVGAGTLEYLPQRLGDAIGPGAVEHLFDLARGAPVGVALQRAGDALPGGDVT
HHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEE
ALQSRTDGGGRPEFHRLVEVRQRGGRAAAAVALVPRGRPVRRRSRASVGCQRHLASSSIA
EEECCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
TATARQRCLICSQSAGASASGPWSSG
HHHHHHHEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nitrite; acceptor

Specific reaction: nitrite + acceptor = nitrate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1552862 [H]