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The map label for this gene is pntB

Identifier: 41409672

GI number: 41409672

Start: 3972189

End: 3973613

Strand: Direct

Name: pntB

Synonym: MAP3574

Alternate gene names: 41409672

Gene position: 3972189-3973613 (Clockwise)

Preceding gene: 41409671

Following gene: 41409673

Centisome position: 82.24

GC content: 67.23

Gene sequence:

>1425_bases
ATGAACTACTTGGTGATCGGCCTCTACATCGTTTCCTTCGCGCTGTTCATCTACGGCCTGATGGGGCTGACCGGGCCCAA
GACGGCGGTGCGCGGCAACCTGATCGCCGCGGTGGGCATGGCCATCGCGGTGGCCGCGACGCTGATCAAGATCCGCCACA
CCGACCAATGGGTGCTGATCATCGCCGGCCTGGTGGTGGGTGTGGTGCTCGGCGTCCCGCCGGCCCGCTACACCAAGATG
ACGGCCATGCCGCAGCTGGTGGCCTTCTTCAACGGCGTCGGAGGTGGCACCGTCGCGCTGATCGCCCTGTCGGAATTCAT
TGAGACATCCGGCTTTTCGGCGTTCCAGCACGGCGAGTCACCGACGGTGCACATCGTGGTGGTGTCGTTGTTCGCCGCGA
TCATCGGATCGATCTCGTTCTGGGGCTCGATCATCGCGTTCGGCAAGCTGCAGGAGATCATCTCCGGCGCCCCGATCGGC
TTCGGCAAGGCCCAGCAGCCGATCAACCTGCTGCTGCTGGCCGGCGCCGTGGCCGCCGCGGTGGTGATCGGTCTGCACGC
CCATCCCGGCAGCGGCGGGGTGTCGCTGTGGTGGATGATCGGGCTGCTGGCCGCCGCCGGCGTGCTGGGCCTGATGGTGG
TGCTGCCCATCGGCGGCGCTGACATGCCGGTGGTCATCTCGCTGCTCAACGCGATGACCGGGCTCTCGGCCGCGGCCGCG
GGGTTGGCGCTGAACAACACCGCGATGATCGTGGCCGGCATGATCGTCGGCGCCTCGGGTTCGATCCTGACCAACCTGAT
GGCCAAGGCGATGAACCGCTCCATCCCGGCGATCGTCGCCGGCGGCTTCGGCGGTGGGGGCGTGGCACCGGGCGGCGGTG
ACGGCGGCGACAAGCACGTCAAGTCCACCTCGGCGGCCGACGCCGCGATCCAGATGGCCTACGCCAACCAGGTGATCGTG
GTGCCCGGTTACGGCCTGGCCGTCGCGCAGGCCCAGCACGCCGTCAAGGACATGGCCGCGCTGCTGGAGGAGAAGGGCGT
GCCGGTGAAGTACGCCATCCACCCGGTGGCCGGCCGGATGCCCGGGCACATGAACGTGCTGCTGGCCGAGGCCGAGGTCG
ACTACGACGCGATGAAGGACATGGACGACATCAACGACGAGTTCGCCCGCACCGACGTCGCGATCGTCATCGGCGCCAAC
GACGTCACCAATCCGGCCGCCCGCAACGAGGCGTCCAGCCCGATCTACGGCATGCCGATTCTCAACGTGGACAAGGCCAA
GTCGGTGATCGTGCTCAAGCGGTCGATGAACTCCGGCTTCGCCGGCATCGACAACCCGCTGTTCTACGCCGAGGGGACGA
CGATGCTGTTCGGCGACGCGAAGAAGTCGGTGACCGAGGTCGCCGAGGAGCTCAAGGCGCTATAA

Upstream 100 bases:

>100_bases
TGTTCGGGACCCTGAACGTCATCGGCGGGTTCATCGTCACCGACCGGATGCTGGGCATGTTCAAGAGCAAGAAACCCGCC
AAGGCTGACGAGGCGGCCAA

Downstream 100 bases:

>100_bases
CTGGCGCTCTAACGCGGTGCCTAGACGGGCGGGTAGGCCGGCGGCGGGTAGCCGTTGCCGTCGGTGACCCCGCGCAACCC
CCAGGTGAGGTACCGCATGA

Product: hypothetical protein

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNYLVIGLYIVSFALFIYGLMGLTGPKTAVRGNLIAAVGMAIAVAATLIKIRHTDQWVLIIAGLVVGVVLGVPPARYTKM
TAMPQLVAFFNGVGGGTVALIALSEFIETSGFSAFQHGESPTVHIVVVSLFAAIIGSISFWGSIIAFGKLQEIISGAPIG
FGKAQQPINLLLLAGAVAAAVVIGLHAHPGSGGVSLWWMIGLLAAAGVLGLMVVLPIGGADMPVVISLLNAMTGLSAAAA
GLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAGGFGGGGVAPGGGDGGDKHVKSTSAADAAIQMAYANQVIV
VPGYGLAVAQAQHAVKDMAALLEEKGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFARTDVAIVIGAN
DVTNPAARNEASSPIYGMPILNVDKAKSVIVLKRSMNSGFAGIDNPLFYAEGTTMLFGDAKKSVTEVAEELKAL

Sequences:

>Translated_474_residues
MNYLVIGLYIVSFALFIYGLMGLTGPKTAVRGNLIAAVGMAIAVAATLIKIRHTDQWVLIIAGLVVGVVLGVPPARYTKM
TAMPQLVAFFNGVGGGTVALIALSEFIETSGFSAFQHGESPTVHIVVVSLFAAIIGSISFWGSIIAFGKLQEIISGAPIG
FGKAQQPINLLLLAGAVAAAVVIGLHAHPGSGGVSLWWMIGLLAAAGVLGLMVVLPIGGADMPVVISLLNAMTGLSAAAA
GLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAGGFGGGGVAPGGGDGGDKHVKSTSAADAAIQMAYANQVIV
VPGYGLAVAQAQHAVKDMAALLEEKGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFARTDVAIVIGAN
DVTNPAARNEASSPIYGMPILNVDKAKSVIVLKRSMNSGFAGIDNPLFYAEGTTMLFGDAKKSVTEVAEELKAL
>Mature_474_residues
MNYLVIGLYIVSFALFIYGLMGLTGPKTAVRGNLIAAVGMAIAVAATLIKIRHTDQWVLIIAGLVVGVVLGVPPARYTKM
TAMPQLVAFFNGVGGGTVALIALSEFIETSGFSAFQHGESPTVHIVVVSLFAAIIGSISFWGSIIAFGKLQEIISGAPIG
FGKAQQPINLLLLAGAVAAAVVIGLHAHPGSGGVSLWWMIGLLAAAGVLGLMVVLPIGGADMPVVISLLNAMTGLSAAAA
GLALNNTAMIVAGMIVGASGSILTNLMAKAMNRSIPAIVAGGFGGGGVAPGGGDGGDKHVKSTSAADAAIQMAYANQVIV
VPGYGLAVAQAQHAVKDMAALLEEKGVPVKYAIHPVAGRMPGHMNVLLAEAEVDYDAMKDMDDINDEFARTDVAIVIGAN
DVTNPAARNEASSPIYGMPILNVDKAKSVIVLKRSMNSGFAGIDNPLFYAEGTTMLFGDAKKSVTEVAEELKAL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=471, Percent_Identity=38.6411889596603, Blast_Score=293, Evalue=4e-79,
Organism=Homo sapiens, GI122939153, Length=471, Percent_Identity=38.6411889596603, Blast_Score=293, Evalue=4e-79,
Organism=Escherichia coli, GI1787886, Length=477, Percent_Identity=44.0251572327044, Blast_Score=353, Evalue=9e-99,
Organism=Caenorhabditis elegans, GI17550456, Length=466, Percent_Identity=37.9828326180258, Blast_Score=305, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 48426; Mature: 48426

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCCCEEEEEEECCCCCCCCCCCCEEEECCCEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]