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The map label for this gene is icd2

Identifier: 41409554

GI number: 41409554

Start: 3836154

End: 3838391

Strand: Reverse

Name: icd2

Synonym: MAP3456c

Alternate gene names: 41409554

Gene position: 3838391-3836154 (Counterclockwise)

Preceding gene: 41409558

Following gene: 41409553

Centisome position: 79.47

GC content: 65.33

Gene sequence:

>2238_bases
GTGAGCGCCGAGAAGCCGACCGTCATCTACACGCTGACCGACGAGGCGCCGCTGCTGGCGACCTACGCGTTCCTGCCGAT
CGTGCGGGCCTTCGCCGAACCGGCGGGCATCGAGATCAAGACCAGCGACATCTCGGTGGCGGCTCGCATCCTGGCCGAGT
TCCCCGAGCACCTGACCGAAGAGCAGCGGGTGCCGGACAACCTGGCCGAGCTGGGCCGGCTGACCAAGCTGGCCGACACC
AACATCATCAAGCTGCCCAACATCAGCGCCTCGGTGCCCCAGCTGATCGCCGCCGTCAAGGAGCTGCAGGGCAAGGGATA
CAAGATCCCCGACTTCCCGCAGAGCCCGAAGACCGACGAGGACCGCGAGATCCGCGAGCGCTACGCCAAGTGCCTGGGCA
GTGCGGTCAATCCCGTTCTGCGGCAAGGCAACTCGGACCGTCGCGCACCCAAGGCGGTCAAGGAGTACGCCCGCAAGCAC
CCGCACCACATGGCGGAGTGGTCGCCGGCCTCGCGCACCCACGTCGCGACCATGAAGCACGGCGACTTCTACCACGGCGA
GAAGTCGATGACGCTGGACCGCGCCCGCAACGTCAAGATGGAGCTGGAGACCAAGAGCGGCAAGACGATCGTGCTCAAGC
CGATGGTCTCGCTGCGCACCGGCGACATCATCGACTCGATGTTCATGAGCAAGAAGGCCCTGGTCGAGTTCTACGAGCAG
CAGATGCAGGACGCCTACGAGACCGGCGTGATGTTCTCGCTGCACGTCAAGGCGACCATGATGAAGGTCAGCCACCCGAT
CGTCTTCGGGCACGCGGTGAAGGTCTTCTACAAGGAGGCCTTCGCCAAGCATCAGGCGCTGTTCGACGAGCTCGGCGTCG
ACGTCAACAACGGGCTGGTCGACCTCTACAGCAAGATCGAGTCGCTGCCGGCGTCGCTGCACGACGAGATCATCCGCGAC
CTGCACGCCTGCCACGAGCACCGGCCCGAGCTGGCCATGGTCGATTCGGCCAAGGGCATCACCAACTTTCACTCGCCCAG
CGACGTGATCGTGGACGCGTCCATGCCGGCGATGATCCGCGCCGGCGGCAAGATGTACGGCGCCGACGGGCGGCAGAAGG
ACACCAAGGCCGTCAACCCCGAGTCCACCTTTTCCCGGATCTACCAGGAGATCATCAACTTCTGCAAAACCCACGGCGCG
TTCGACCCGGCGACCATGGGCACGGTGCCCAACGTCGGGCTGATGGCGCAGCAGGCCGAGGAATACGGTTCGCACGACAA
GACATTCGAGATCCCCGAGGACGGCGTCGCCAACATCGTCGACCTGGACACGGGGGAGGTCCTGCTGACCCAGAACGTCG
AGACCGGCGACATCTGGCGGATGCCGATCGTGCGCGACGAACCGATCCGGGACTGGGTCAAGCTGGCCGTCACCCGGGCC
CGCAACTCGGGGATGACGGCGGTGTTCTGGCTGGACACCGAACGCCCGCACGAGGTCGAGCTGCGCAAGAAGGTCAAGGA
ATACCTCAAGGAGCACGACACCGAGGGCCTGCACATCCAGATCATGCCGCAGGTGTGGGCCATGCGCTACACGCTGGAAC
GGGCCATGCGCGGCCAGGACACCATCGCCGTCACCGGAAACATCCTGCGCGACTACCTGACCGACCTGTTCCCCATCCTG
GAGCTGGGCACCAGCGCCAAGATGCTGTCCATCGTGCCGTTGATGTCCGGCGGCGGCATGTATGAGACCGGAGCCGGCGG
GTCGGCGCCCAAGCATGTGCACCAGCTCGTCGAGGAGAACCATCTGCGGTGGGACTCCCTCGGTGAATTCCTGGCTCTGG
GAGCGTGTTTCGAAGACATCGGCATCAAGACCGGTAACCAGCGGGCCAAGCTGCTGGGCAAGACGCTGGATGCCGCCATC
GGAAAGCTGTTGGAGAACAACAAGAGTCCGTCGCGCAAGACCGGCGAGCTCGACAACCGGGGCAGCCAGTTCTACCTGGC
GCTGTACTGGGCCCAAGAGCTCGCCGCGCAAAACGACGACGACGAGCTGCGCCGGCATTTCGCCGCGCTGGCCGCGTCGT
TGGGCGAAAACGAGCAGCGGATCGTCGAGGAGCTCGCCGAGGTGCAGGGCCGGCCGGTCGACATCGGCGGCTACTACCAG
CCCGACAGCGAGAAGACCACCGCGGTGATGCGGCCGAGCAAGACGTTCAACGAGGCGCTGGCCGCGTCGCAGCGCTGA

Upstream 100 bases:

>100_bases
CAGACGCGCCCCGACACCTGTCCAAACACCCTTGATAACGTGGCAGATAGATTGCTGAGCCCCACAATGCGAACCCATCA
TTGACGCCGGGAGAGGGACC

Downstream 100 bases:

>100_bases
CATGTCCAACCCCGCCAACACGTCCAAGATCAAGGTCAAGGGCCGCGTCGTCGAGCTCGACGGTGACGAGATGACCCGGG
TCATCTGGAAGATGATCAAG

Product: Icd2

Products: NA

Alternate protein names: IDH; Oxalosuccinate decarboxylase [H]

Number of amino acids: Translated: 745; Mature: 744

Protein sequence:

>745_residues
MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTEEQRVPDNLAELGRLTKLADT
NIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDEDREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKH
PHHMAEWSPASRTHVATMKHGDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ
QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLVDLYSKIESLPASLHDEIIRD
LHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIRAGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGA
FDPATMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA
RNSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQDTIAVTGNILRDYLTDLFPIL
ELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEENHLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAI
GKLLENNKSPSRKTGELDNRGSQFYLALYWAQELAAQNDDDELRRHFAALAASLGENEQRIVEELAEVQGRPVDIGGYYQ
PDSEKTTAVMRPSKTFNEALAASQR

Sequences:

>Translated_745_residues
MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTEEQRVPDNLAELGRLTKLADT
NIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDEDREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKH
PHHMAEWSPASRTHVATMKHGDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ
QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLVDLYSKIESLPASLHDEIIRD
LHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIRAGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGA
FDPATMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA
RNSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQDTIAVTGNILRDYLTDLFPIL
ELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEENHLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAI
GKLLENNKSPSRKTGELDNRGSQFYLALYWAQELAAQNDDDELRRHFAALAASLGENEQRIVEELAEVQGRPVDIGGYYQ
PDSEKTTAVMRPSKTFNEALAASQR
>Mature_744_residues
SAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTEEQRVPDNLAELGRLTKLADTN
IIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDEDREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHP
HHMAEWSPASRTHVATMKHGDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQQ
MQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLVDLYSKIESLPASLHDEIIRDL
HACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIRAGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGAF
DPATMGTVPNVGLMAQQAEEYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRAR
NSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQDTIAVTGNILRDYLTDLFPILE
LGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEENHLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAIG
KLLENNKSPSRKTGELDNRGSQFYLALYWAQELAAQNDDDELRRHFAALAASLGENEQRIVEELAEVQGRPVDIGGYYQP
DSEKTTAVMRPSKTFNEALAASQR

Specific function: Unknown

COG id: COG2838

COG function: function code C; Monomeric isocitrate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monomeric-type IDH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001804
- InterPro:   IPR004436 [H]

Pfam domain/function: PF03971 IDH [H]

EC number: =1.1.1.42 [H]

Molecular weight: Translated: 83082; Mature: 82951

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHH
EQRVPDNLAELGRLTKLADTNIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDE
HHCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHHMAEWSPASRTHVATMKH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEC
GDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ
CCCCCCCCCCCHHHHCCCEEEEEECCCCEEEEECCHHHHCHHHHHHHHHHHHHHHHHHHH
QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLV
HHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DLYSKIESLPASLHDEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCHHHH
AGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGAFDPATMGTVPNVGLMAQQAE
CCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHH
EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA
HHCCCCCEEECCCCCCCCEEECCCCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHH
RNSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCC
TIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEEN
EEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHC
HLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAIGKLLENNKSPSRKTGELDNR
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GSQFYLALYWAQELAAQNDDDELRRHFAALAASLGENEQRIVEELAEVQGRPVDIGGYYQ
CCEEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
PDSEKTTAVMRPSKTFNEALAASQR
CCCCCCEEEECCCHHHHHHHHCCCC
>Mature Secondary Structure 
SAEKPTVIYTLTDEAPLLATYAFLPIVRAFAEPAGIEIKTSDISVAARILAEFPEHLTE
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHH
EQRVPDNLAELGRLTKLADTNIIKLPNISASVPQLIAAVKELQGKGYKIPDFPQSPKTDE
HHCCCHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
DREIRERYAKCLGSAVNPVLRQGNSDRRAPKAVKEYARKHPHHMAEWSPASRTHVATMKH
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEC
GDFYHGEKSMTLDRARNVKMELETKSGKTIVLKPMVSLRTGDIIDSMFMSKKALVEFYEQ
CCCCCCCCCCCHHHHCCCEEEEEECCCCEEEEECCHHHHCHHHHHHHHHHHHHHHHHHHH
QMQDAYETGVMFSLHVKATMMKVSHPIVFGHAVKVFYKEAFAKHQALFDELGVDVNNGLV
HHHHHHHCCCEEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
DLYSKIESLPASLHDEIIRDLHACHEHRPELAMVDSAKGITNFHSPSDVIVDASMPAMIR
HHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCEEEECCCCHHHH
AGGKMYGADGRQKDTKAVNPESTFSRIYQEIINFCKTHGAFDPATMGTVPNVGLMAQQAE
CCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHH
EYGSHDKTFEIPEDGVANIVDLDTGEVLLTQNVETGDIWRMPIVRDEPIRDWVKLAVTRA
HHCCCCCEEECCCCCCCCEEECCCCCEEEECCCCCCCEEECCCCCCCHHHHHHHHHHHHH
RNSGMTAVFWLDTERPHEVELRKKVKEYLKEHDTEGLHIQIMPQVWAMRYTLERAMRGQD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCC
TIAVTGNILRDYLTDLFPILELGTSAKMLSIVPLMSGGGMYETGAGGSAPKHVHQLVEEN
EEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHC
HLRWDSLGEFLALGACFEDIGIKTGNQRAKLLGKTLDAAIGKLLENNKSPSRKTGELDNR
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GSQFYLALYWAQELAAQNDDDELRRHFAALAASLGENEQRIVEELAEVQGRPVDIGGYYQ
CCEEEEEEEEHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCC
PDSEKTTAVMRPSKTFNEALAASQR
CCCCCCEEEECCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12005040; 4149369; 12467571 [H]