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The map label for this gene is aphA [H]

Identifier: 41409488

GI number: 41409488

Start: 3765375

End: 3766970

Strand: Reverse

Name: aphA [H]

Synonym: MAP3390c

Alternate gene names: 41409488

Gene position: 3766970-3765375 (Counterclockwise)

Preceding gene: 41409489

Following gene: 41409487

Centisome position: 77.99

GC content: 69.3

Gene sequence:

>1596_bases
GTGACCGCGCCGCGTCCGCTCCGGCTCACGCAGCTGACCGTGCGGGGATGGCTGGCCCTGGTGCTGTGGATCATGGGCAC
GACGGTGCTGGTCGGGGCGGTGCTGCTGCACCGCACCGACCAGGTGTCGCGGCAGGTGGCCGACGGTGTCGGGCCGGCGC
GGGTCGCGGCGGCCCGGCTGCAGGCGGCGCTGCGGGACCAGGAAACCGGCCTGCGCGGCTACCTGATCGCCGCGGACCGG
CAGTTCCTGGCGCCCTACTACGACGGGCAGCGCACCGAGCAGGCGGCCGCCGACGAGATTCGCCGGCTGGTGGGCGGCAA
CGCCGGCAACACCGAGCTGATCGCCGACCTGGACGCGGTGGAGTCGGCCGCCGCGGACTGGCGCACCAACTACGCCGAAC
CCGTCATCGCCAGCGTCACCCCCAGGGCCCCCGCCGTCGTCAGCGCCCCGACCGCCGACCTCGGCAAGGCCAAATTCGAC
CATCTGCGAGCGCTTTTCGAGACCCAGAACATGCATCTGGCGCAGGCGGCGGCGAGTGCGACCGCCGAGCTGCACGAGAT
CAACGGCTGGCGCGACTGGGTGCTGGGTGCCATGGTGCTGGCCATTTTGGGGACGGGTCTGTTCCTGGGCTTGTTCAGCC
GCGCCGCCATCACCCGCCCGATCGCGCAGCTGGCCGCGTCCTGCCGGCGCATCACCGAGGGCAACTTCGTCGAAACGATC
GTTGCGCCCAAGCGGCCCAAGGATATTCGCGACATGGCCATCGACGTGGAGAACATGCGCAAGCGCATGGTCGAAGAACT
CGACATGTCGCGGTCGGCCCAGGAGCAGCTGGACGAGCAGGCCGCCGAATTGCGGCGCTCCAACACCGAACTCGAGCAGT
TCGCCTACGTCGCCTCCCACGACCTGCAGGAGCCGCTGCGCAAGGTGGCGTCGTTCTGCCAGCTGCTGGAGCGCCGGTAC
GGCGACCAGCTCGACGAGCGCGGCCTGGAGTACATCGGGTTCGCGGTCGACGGCGCCAAACGGATGCAGGCGCTGATCAA
CGACCTGCTCACCTTCTCCCGGGTGGGCCGGCTGGGCACCACCGAGGCCGAGGTGCAGCTGGATGCCACGCTGGACGCCG
GCCTGGCCAACCTGGCCGCCGCCGTCGAGGAAACCGGCGCCGAGATCGTGCGCCCCGCCGAACTGCCGCGGATCGTCGGG
GACCCGATGCTGCTGACCATGTTGTGGCAGAACCTGATCGGCAATGCGATCAAGTTCCGGCACAAGGATCGCCGGCCCCG
CGTCGTCATCGAATGCGCCCCCGGCGAAGGCACCCACGACGGCGAGTGGCTGCTGAGCGTGTCGGACAACGGCATCGGCA
TCCCGGAGGAGTTCTCCGACAAGGTCTTCGTCATCTTCCAGCGGCTGCACGGCCGGGAGGTGTACGCCGGCACCGGGGTC
GGCCTGGCGTTGGTGAAGAAGATCGTCGAGCACCACGGCGGCACCGTCCGGATCGACACGTCCTACACCGACGGGACCCG
ATTCGAATTCAGTTTGCCCATGCCCGGACCCGTCGACGAAACGGACGCAGTCGCTTTGGAAGGAGCGCAGCAATGA

Upstream 100 bases:

>100_bases
CGTTCGTCGACGCCCTGATCGACGGCGCCCAGCGACTGGCCCAGCCGCGCGGCGGCCTCACCGATGACATCGCCGTGCTC
CGCGTCGAGAGGACCATCAC

Downstream 100 bases:

>100_bases
CAACGGCCGGTAGAGCCATCGACATCCTGCTCGTCGAGGACGACCCCGGAGACGAGCTGATCACGCGAGAAGCCTTCGAG
CACAACAAACTCAACAACAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MTAPRPLRLTQLTVRGWLALVLWIMGTTVLVGAVLLHRTDQVSRQVADGVGPARVAAARLQAALRDQETGLRGYLIAADR
QFLAPYYDGQRTEQAAADEIRRLVGGNAGNTELIADLDAVESAAADWRTNYAEPVIASVTPRAPAVVSAPTADLGKAKFD
HLRALFETQNMHLAQAAASATAELHEINGWRDWVLGAMVLAILGTGLFLGLFSRAAITRPIAQLAASCRRITEGNFVETI
VAPKRPKDIRDMAIDVENMRKRMVEELDMSRSAQEQLDEQAAELRRSNTELEQFAYVASHDLQEPLRKVASFCQLLERRY
GDQLDERGLEYIGFAVDGAKRMQALINDLLTFSRVGRLGTTEAEVQLDATLDAGLANLAAAVEETGAEIVRPAELPRIVG
DPMLLTMLWQNLIGNAIKFRHKDRRPRVVIECAPGEGTHDGEWLLSVSDNGIGIPEEFSDKVFVIFQRLHGREVYAGTGV
GLALVKKIVEHHGGTVRIDTSYTDGTRFEFSLPMPGPVDETDAVALEGAQQ

Sequences:

>Translated_531_residues
MTAPRPLRLTQLTVRGWLALVLWIMGTTVLVGAVLLHRTDQVSRQVADGVGPARVAAARLQAALRDQETGLRGYLIAADR
QFLAPYYDGQRTEQAAADEIRRLVGGNAGNTELIADLDAVESAAADWRTNYAEPVIASVTPRAPAVVSAPTADLGKAKFD
HLRALFETQNMHLAQAAASATAELHEINGWRDWVLGAMVLAILGTGLFLGLFSRAAITRPIAQLAASCRRITEGNFVETI
VAPKRPKDIRDMAIDVENMRKRMVEELDMSRSAQEQLDEQAAELRRSNTELEQFAYVASHDLQEPLRKVASFCQLLERRY
GDQLDERGLEYIGFAVDGAKRMQALINDLLTFSRVGRLGTTEAEVQLDATLDAGLANLAAAVEETGAEIVRPAELPRIVG
DPMLLTMLWQNLIGNAIKFRHKDRRPRVVIECAPGEGTHDGEWLLSVSDNGIGIPEEFSDKVFVIFQRLHGREVYAGTGV
GLALVKKIVEHHGGTVRIDTSYTDGTRFEFSLPMPGPVDETDAVALEGAQQ
>Mature_530_residues
TAPRPLRLTQLTVRGWLALVLWIMGTTVLVGAVLLHRTDQVSRQVADGVGPARVAAARLQAALRDQETGLRGYLIAADRQ
FLAPYYDGQRTEQAAADEIRRLVGGNAGNTELIADLDAVESAAADWRTNYAEPVIASVTPRAPAVVSAPTADLGKAKFDH
LRALFETQNMHLAQAAASATAELHEINGWRDWVLGAMVLAILGTGLFLGLFSRAAITRPIAQLAASCRRITEGNFVETIV
APKRPKDIRDMAIDVENMRKRMVEELDMSRSAQEQLDEQAAELRRSNTELEQFAYVASHDLQEPLRKVASFCQLLERRYG
DQLDERGLEYIGFAVDGAKRMQALINDLLTFSRVGRLGTTEAEVQLDATLDAGLANLAAAVEETGAEIVRPAELPRIVGD
PMLLTMLWQNLIGNAIKFRHKDRRPRVVIECAPGEGTHDGEWLLSVSDNGIGIPEEFSDKVFVIFQRLHGREVYAGTGVG
LALVKKIVEHHGGTVRIDTSYTDGTRFEFSLPMPGPVDETDAVALEGAQQ

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=365, Percent_Identity=26.027397260274, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=25.3968253968254, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=27.7551020408163, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=26.1904761904762, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=25.7142857142857, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787894, Length=181, Percent_Identity=30.3867403314917, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58143; Mature: 58012

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRPLRLTQLTVRGWLALVLWIMGTTVLVGAVLLHRTDQVSRQVADGVGPARVAAARL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QAALRDQETGLRGYLIAADRQFLAPYYDGQRTEQAAADEIRRLVGGNAGNTELIADLDAV
HHHHHHHCCCCCEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ESAAADWRTNYAEPVIASVTPRAPAVVSAPTADLGKAKFDHLRALFETQNMHLAQAAASA
HHHHHHHHCCCCCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TAELHEINGWRDWVLGAMVLAILGTGLFLGLFSRAAITRPIAQLAASCRRITEGNFVETI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
VAPKRPKDIRDMAIDVENMRKRMVEELDMSRSAQEQLDEQAAELRRSNTELEQFAYVASH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DLQEPLRKVASFCQLLERRYGDQLDERGLEYIGFAVDGAKRMQALINDLLTFSRVGRLGT
HHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCC
TEAEVQLDATLDAGLANLAAAVEETGAEIVRPAELPRIVGDPMLLTMLWQNLIGNAIKFR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCCHHHHHHHHHHHHHHHHHHH
HKDRRPRVVIECAPGEGTHDGEWLLSVSDNGIGIPEEFSDKVFVIFQRLHGREVYAGTGV
HCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHCCHHHHHHHHHCCCEEECCCCH
GLALVKKIVEHHGGTVRIDTSYTDGTRFEFSLPMPGPVDETDAVALEGAQQ
HHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHCCCCCC
>Mature Secondary Structure 
TAPRPLRLTQLTVRGWLALVLWIMGTTVLVGAVLLHRTDQVSRQVADGVGPARVAAARL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QAALRDQETGLRGYLIAADRQFLAPYYDGQRTEQAAADEIRRLVGGNAGNTELIADLDAV
HHHHHHHCCCCCEEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ESAAADWRTNYAEPVIASVTPRAPAVVSAPTADLGKAKFDHLRALFETQNMHLAQAAASA
HHHHHHHHCCCCCCCEECCCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
TAELHEINGWRDWVLGAMVLAILGTGLFLGLFSRAAITRPIAQLAASCRRITEGNFVETI
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEC
VAPKRPKDIRDMAIDVENMRKRMVEELDMSRSAQEQLDEQAAELRRSNTELEQFAYVASH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DLQEPLRKVASFCQLLERRYGDQLDERGLEYIGFAVDGAKRMQALINDLLTFSRVGRLGT
HHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCC
TEAEVQLDATLDAGLANLAAAVEETGAEIVRPAELPRIVGDPMLLTMLWQNLIGNAIKFR
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCHHHCCHHHHHHHHHHHHHHHHHHH
HKDRRPRVVIECAPGEGTHDGEWLLSVSDNGIGIPEEFSDKVFVIFQRLHGREVYAGTGV
HCCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHHCCHHHHHHHHHCCCEEECCCCH
GLALVKKIVEHHGGTVRIDTSYTDGTRFEFSLPMPGPVDETDAVALEGAQQ
HHHHHHHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]