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The map label for this gene is catB

Identifier: 41409334

GI number: 41409334

Start: 3590965

End: 3593085

Strand: Direct

Name: catB

Synonym: MAP3236

Alternate gene names: 41409334

Gene position: 3590965-3593085 (Clockwise)

Preceding gene: 41409330

Following gene: 41409336

Centisome position: 74.35

GC content: 67.23

Gene sequence:

>2121_bases
ATGGCCACCGACCACACTTCGGGTGCGCCCGATCCCAAGCAGCGCGATCTGGAGTCCGCGCGGTTCCGCCGCGACACCGG
ATACCTGACCACGCAGCAGGGCGTGCGCGTCGACCACACCGACGATGCGCTCACCGTCGGCGAGCGGGGTCCGACGCTGC
TGGAGGATTTCCACGCCCGGGAGAAGATCACCCACTTCGACCACGAGCGCATCCCGGAGCGTGTGGTGCATGCGCGCGGG
GCCGGCGCCTACGGCTATTTCGAACCGTACGACGACCGGTTGGCGCAGTACACGGCGGCGAAATTTCTGACCTCGCCGGG
CACCAGGACGCCGGTGTTCGTGCGTTTTTCGACGGTCGCCGGATCGCGCGGTTCGGCCGACACCGTCCGCGACGTGCGCG
GGTTCGCCACCAAGTTCTATACCGAACAAGGCAATTACGACTTGGTGGGCAACAACTTCCCGGTGTTCTTCATCCAGGAC
GGCATCAAGTTCCCCGACTTCGTGCACGCGGTGAAACCCGAGCCGCACAACGAGATTCCGCAGGCGCAGTCGGCGCACGA
CACGCTGTGGGACTTCGTGTCGCTGCAGCCCGAGACGTTGCACGCCATCATGTGGCTGATGTCGGACCGGGCGCTGCCGC
GCAGCTACCGCATGATGCAGGGGTTCGGGGTGCACACCTTCCGGCTGGTGAACGCCCGCGGCGAGGGGACTTTCGTGAAG
TTCCACTGGAAGCCCCGACTCGGCGTGCACTCGCTGATCTGGGACGAATGCCAGAAGATCGCCGGCAAAGACCCCGATTA
CAACCGCCGCGACCTGTGGGAGGCCATCGAATCCCGCCAGTACCCGGAGTGGGAGCTGGGCGTGCAGCTGGTCGCCGAGG
ACGACGAGTTCAGCTTCGACTTCGATCTGCTGGACGCGACGAAAATCATTCCGGAAGAACAGGTTCCGGTATTGCCGGTG
GGCAAGATGGTGTTGAACCGCAACCCCGACAACTTCTTCGCCGAGACCGAGCAGGTCGCTTTTCACACCGCCAACGTGGT
GCCGGGCATCGATTTCACCAACGACCCGTTGCTGCAGTTCCGCAACTTCTCCTATCTGGACACGCAGCTGATCCGGTTGG
GCGGCCCCAACTTCGCGCAGCTGCCGGTCAACCGCCCGGTGGCGCAGGTGCGGACCAACCAGCACGACGGTTACGGGCAG
CACACGATTCCGCAGGGCCGGTCCAGTTACTTCAAGAACAGCATCGGCGGCGGTTGTCCCGCACTGGCCGACGAGGACGT
GTTCCGGCACTACACCCAGCGGGTGGACGGGCAGACGATGCGCAAGCGCGCCGAGGCGTTCCAGAACCACTACGGCCAGG
CGCGGATGTTCTTCAAGAGCATGTCGCCGGTGGAGGCCGAACACATCGTGGCCGCCTTCGCCTTCGAACTCGGCAAGGTG
GAGATGCCCGAAATCCGTTCCGCGGTGGTGGCACAACTCGCCCGCGTCGATGACCAGCTGGCCGCCCAGGTCGCGGCGAA
ACTGGGGCTGCCCGAGCCGCCGGAGGAGCAGGTGGACGAGTCGGCACCGGTTTCCCCGGCGCTTTCGCAGGTCACCGACG
GCGGCGACACCATCGCGTCGCGCCGGATCGCGGTGCTGGCCGCCGACGGCGTCGACGTGGTGGGCACGCAACGCTTCACC
GAGCTGATGGAGCAGCGCGGCGCGGTGGTCGAGGTGCTGGCCCCGGTGGCCGGCGGCACGCTGGCGGGTGGGTCCGGCGG
CGAGCTGCGGGTGGACCGGTCCTTCACGACGATGGCGTCGGTGCTCTACGACGCGGTGGTGGTGGCGTGCGGACCGCGGT
CGGTGTCGACGCTGTCCGACGACGGCTACGCCGTGCACTTCGTCACCGAGGCCTACAAACACCTCAAGCCGATCGGCGCC
TACGGGGCCGGTGTCGACCTGCTCCGCAAGGCCGGCATCGACAACCGGCTCGCCGAGGACACCGACGTGCTCAACGACCA
AGCGGTGGTCACCACCAAGGCCGCCGCCGACGAGCTGCCCGAGCGCTTCGCCGAGGAATTCGCCGCCGCGCTCGCGCAGC
ACCGGTGCTGGCAGCGGCGCACCGACGCGGTGCCGGCCTGA

Upstream 100 bases:

>100_bases
CAACCCACCCACCGATGGATAGGGGCACAGCCGCGCCGTTTGCGCGGGTGAGCCGGTGGTACTCCCCCACGGTCGAAAGG
GTCGAAAGGAGAGGCAACAC

Downstream 100 bases:

>100_bases
AAGCCGGCCGAAGACCGCCGAAAGGTTTTCCCGGCCGCCGGGACGGGCATCCGGCTCAGAAGGCGTCATCGTGGACAGGA
GGACAAGTCATGCCGCGCTC

Product: CatB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 705

Protein sequence:

>706_residues
MATDHTSGAPDPKQRDLESARFRRDTGYLTTQQGVRVDHTDDALTVGERGPTLLEDFHAREKITHFDHERIPERVVHARG
AGAYGYFEPYDDRLAQYTAAKFLTSPGTRTPVFVRFSTVAGSRGSADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQD
GIKFPDFVHAVKPEPHNEIPQAQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVNARGEGTFVK
FHWKPRLGVHSLIWDECQKIAGKDPDYNRRDLWEAIESRQYPEWELGVQLVAEDDEFSFDFDLLDATKIIPEEQVPVLPV
GKMVLNRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLIRLGGPNFAQLPVNRPVAQVRTNQHDGYGQ
HTIPQGRSSYFKNSIGGGCPALADEDVFRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAFELGKV
EMPEIRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSPALSQVTDGGDTIASRRIAVLAADGVDVVGTQRFT
ELMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMASVLYDAVVVACGPRSVSTLSDDGYAVHFVTEAYKHLKPIGA
YGAGVDLLRKAGIDNRLAEDTDVLNDQAVVTTKAAADELPERFAEEFAAALAQHRCWQRRTDAVPA

Sequences:

>Translated_706_residues
MATDHTSGAPDPKQRDLESARFRRDTGYLTTQQGVRVDHTDDALTVGERGPTLLEDFHAREKITHFDHERIPERVVHARG
AGAYGYFEPYDDRLAQYTAAKFLTSPGTRTPVFVRFSTVAGSRGSADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQD
GIKFPDFVHAVKPEPHNEIPQAQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVNARGEGTFVK
FHWKPRLGVHSLIWDECQKIAGKDPDYNRRDLWEAIESRQYPEWELGVQLVAEDDEFSFDFDLLDATKIIPEEQVPVLPV
GKMVLNRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLIRLGGPNFAQLPVNRPVAQVRTNQHDGYGQ
HTIPQGRSSYFKNSIGGGCPALADEDVFRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAFELGKV
EMPEIRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSPALSQVTDGGDTIASRRIAVLAADGVDVVGTQRFT
ELMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMASVLYDAVVVACGPRSVSTLSDDGYAVHFVTEAYKHLKPIGA
YGAGVDLLRKAGIDNRLAEDTDVLNDQAVVTTKAAADELPERFAEEFAAALAQHRCWQRRTDAVPA
>Mature_705_residues
ATDHTSGAPDPKQRDLESARFRRDTGYLTTQQGVRVDHTDDALTVGERGPTLLEDFHAREKITHFDHERIPERVVHARGA
GAYGYFEPYDDRLAQYTAAKFLTSPGTRTPVFVRFSTVAGSRGSADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQDG
IKFPDFVHAVKPEPHNEIPQAQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVNARGEGTFVKF
HWKPRLGVHSLIWDECQKIAGKDPDYNRRDLWEAIESRQYPEWELGVQLVAEDDEFSFDFDLLDATKIIPEEQVPVLPVG
KMVLNRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQFRNFSYLDTQLIRLGGPNFAQLPVNRPVAQVRTNQHDGYGQH
TIPQGRSSYFKNSIGGGCPALADEDVFRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAFELGKVE
MPEIRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSPALSQVTDGGDTIASRRIAVLAADGVDVVGTQRFTE
LMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMASVLYDAVVVACGPRSVSTLSDDGYAVHFVTEAYKHLKPIGAY
GAGVDLLRKAGIDNRLAEDTDVLNDQAVVTTKAAADELPERFAEEFAAALAQHRCWQRRTDAVPA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=391, Percent_Identity=48.5933503836317, Blast_Score=369, Evalue=1e-102,
Organism=Escherichia coli, GI48994891, Length=707, Percent_Identity=51.0608203677511, Blast_Score=686, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147792, Length=473, Percent_Identity=44.6088794926004, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI25151141, Length=494, Percent_Identity=43.9271255060729, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71998444, Length=480, Percent_Identity=42.7083333333333, Blast_Score=373, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320462, Length=346, Percent_Identity=46.8208092485549, Blast_Score=315, Evalue=2e-86,
Organism=Saccharomyces cerevisiae, GI6321525, Length=338, Percent_Identity=43.7869822485207, Blast_Score=284, Evalue=3e-77,
Organism=Drosophila melanogaster, GI17981717, Length=398, Percent_Identity=47.2361809045226, Blast_Score=365, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19920968, Length=391, Percent_Identity=45.5242966751918, Blast_Score=348, Evalue=7e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 78373; Mature: 78241

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATDHTSGAPDPKQRDLESARFRRDTGYLTTQQGVRVDHTDDALTVGERGPTLLEDFHAR
CCCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCEEECCCCCHHHHHHHHH
EKITHFDHERIPERVVHARGAGAYGYFEPYDDRLAQYTAAKFLTSPGTRTPVFVRFSTVA
HHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEC
GSRGSADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQDGIKFPDFVHAVKPEPHNEIP
CCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCC
QAQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVNARGEGTFVK
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEE
FHWKPRLGVHSLIWDECQKIAGKDPDYNRRDLWEAIESRQYPEWELGVQLVAEDDEFSFD
EEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHCEEEEECCCCCCCE
FDLLDATKIIPEEQVPVLPVGKMVLNRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQF
EEHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHH
RNFSYLDTQLIRLGGPNFAQLPVNRPVAQVRTNQHDGYGQHTIPQGRSSYFKNSIGGGCP
CCCCHHHHHHHEECCCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
ALADEDVFRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAFELGKV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
EMPEIRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSPALSQVTDGGDTIAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHCCCCHHHHH
RRIAVLAADGVDVVGTQRFTELMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMAS
CEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCCCCEEECCHHHHHHH
VLYDAVVVACGPRSVSTLSDDGYAVHFVTEAYKHLKPIGAYGAGVDLLRKAGIDNRLAED
HHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHCH
TDVLNDQAVVTTKAAADELPERFAEEFAAALAQHRCWQRRTDAVPA
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ATDHTSGAPDPKQRDLESARFRRDTGYLTTQQGVRVDHTDDALTVGERGPTLLEDFHAR
CCCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCEEECCCCCEEECCCCCHHHHHHHHH
EKITHFDHERIPERVVHARGAGAYGYFEPYDDRLAQYTAAKFLTSPGTRTPVFVRFSTVA
HHHHHCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEC
GSRGSADTVRDVRGFATKFYTEQGNYDLVGNNFPVFFIQDGIKFPDFVHAVKPEPHNEIP
CCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCC
QAQSAHDTLWDFVSLQPETLHAIMWLMSDRALPRSYRMMQGFGVHTFRLVNARGEGTFVK
CCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEEECCCCCCEEE
FHWKPRLGVHSLIWDECQKIAGKDPDYNRRDLWEAIESRQYPEWELGVQLVAEDDEFSFD
EEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHCEEEEECCCCCCCE
FDLLDATKIIPEEQVPVLPVGKMVLNRNPDNFFAETEQVAFHTANVVPGIDFTNDPLLQF
EEHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHH
RNFSYLDTQLIRLGGPNFAQLPVNRPVAQVRTNQHDGYGQHTIPQGRSSYFKNSIGGGCP
CCCCHHHHHHHEECCCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCCCCC
ALADEDVFRHYTQRVDGQTMRKRAEAFQNHYGQARMFFKSMSPVEAEHIVAAFAFELGKV
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
EMPEIRSAVVAQLARVDDQLAAQVAAKLGLPEPPEEQVDESAPVSPALSQVTDGGDTIAS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHCCCCHHHHH
RRIAVLAADGVDVVGTQRFTELMEQRGAVVEVLAPVAGGTLAGGSGGELRVDRSFTTMAS
CEEEEEEECCCCCHHHHHHHHHHHHCCCEEEHHHHHCCCCCCCCCCCCEEECCHHHHHHH
VLYDAVVVACGPRSVSTLSDDGYAVHFVTEAYKHLKPIGAYGAGVDLLRKAGIDNRLAED
HHHHHHHHCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHCH
TDVLNDQAVVTTKAAADELPERFAEEFAAALAQHRCWQRRTDAVPA
HHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8821941 [H]