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The map label for this gene is fadE12_3

Identifier: 41409294

GI number: 41409294

Start: 3547033

End: 3548271

Strand: Direct

Name: fadE12_3

Synonym: MAP3196

Alternate gene names: 41409294

Gene position: 3547033-3548271 (Clockwise)

Preceding gene: 41409293

Following gene: 41409295

Centisome position: 73.44

GC content: 67.47

Gene sequence:

>1239_bases
GTGGATTTCACCCTGCCCGAACACCTTCCGGGCGTGCTCGCCGAGATGGACGCGTTCATCGAGGACGAGATCAAGCCGCT
GGAGCGCGAGCACATCCAGTATTTCGACCAGCGCCGCGAGCATGCCCGCACCGATTGGGACAACGACGGGATCCCCACCC
GCGAATGGGAGGACCTGCTGGCCGAGATGCGCCGGCGGGCCGACCGGGCGGGCTGGCTGCGGTACGGATTGCCCGCGTCG
CTGGGGGGTCGCGACGGCAGCAACGTCGACATGGCGGTCATTCGGGAACACCTGGCGCACAAGGGTCTTGGCCTGCACAA
CGACCTGCAGAACGAGTCGTCGATCGTCGGGAACTTCCCGCAGGTGATCATGATGGAGCGGTTCGGCACCGACGAACAGC
GCCGGGAGTGGTCGCAGGCGCTGATCACCGGGGAACGTTCCATGGCGTTCGGCCTGACCGAGCCGCAGCACGGCTCGGAC
GCCACCTGGCTTCAGACCCGCGCCGAACGCGACGGTGACGGCTGGGTGATCAACGGCGCCAAGCGATTCAACACCGGCGT
GCACCGCGCCACCCACGACCTGATCTTCGCCCGCACCTCCGGTGAGCCCGGGGCCGCGGTGGGCATCACCGCGTTCCTGG
TGCCGACCGAAGCGCCCGGATTCACGGTGCCCTACTACTGGTGGACGTTCAACATGCCCACCGACCACGGCGAGGTCGAG
CTGACCGATGTCCGGGTGCCCGCCGACGCGGTGCTCGGTGAGGTGGACCGCGGACTCGAAGTCGCGCAAACCTTCCTGCA
CGAGAACAGGATTCGGCAAGCGGCCAGCAGCCTGGGTGCCGCCCAGTACTGCATCGACCGGGCCGCCGAATACGCCGGCA
GCCGAACGGTGTTCGGCAAACCGCTGTCGGTCAACCAGGCCGTGCAATGGCCGCTGGCCGAACTGCAGACCGAAGCCCAG
ATGGTGCGGCTGCTCGTGCAGTACGCGGCCTGGCACCTGGACCGCGACCACCACATGGAGGTATCCGACAAGGTGTCGAT
GGCCAACTACCGGGCCAACCGGCTGGTCTGCGACGCCGCCGACCGGGCCATGCAGATCTTCGGCGGCCTCGGCTACAGCC
GGCACGAACCGTTCGAGCACATCTACCGCCATCACCGCCGCTACCGGATCACCGAGGGCGCCGAGGAGATCCAGATCCGC
CGGGTGGCGCAGCGGCTGTTCAAATTCGGCAAGAAGTGA

Upstream 100 bases:

>100_bases
GGCCCGTCCGGTCTGGGTATCGAGATCAGCGACGAGGACGCCATCGCCACCCTCTCGACGATCTGGAAGAAAACCCTCTA
CGGCGTGTAAGGAGACAGCT

Downstream 100 bases:

>100_bases
TGGACAGCGACGCGGCCGAACTGCGCCCCAAACTGGAAGGGGTGCTGGCCACCGTGCTCGGTGCCGGCACTGCCGTCGAG
CAGCTGCGCACGCTGACCGG

Product: FadE12_3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 412

Protein sequence:

>412_residues
MDFTLPEHLPGVLAEMDAFIEDEIKPLEREHIQYFDQRREHARTDWDNDGIPTREWEDLLAEMRRRADRAGWLRYGLPAS
LGGRDGSNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFPQVIMMERFGTDEQRREWSQALITGERSMAFGLTEPQHGSD
ATWLQTRAERDGDGWVINGAKRFNTGVHRATHDLIFARTSGEPGAAVGITAFLVPTEAPGFTVPYYWWTFNMPTDHGEVE
LTDVRVPADAVLGEVDRGLEVAQTFLHENRIRQAASSLGAAQYCIDRAAEYAGSRTVFGKPLSVNQAVQWPLAELQTEAQ
MVRLLVQYAAWHLDRDHHMEVSDKVSMANYRANRLVCDAADRAMQIFGGLGYSRHEPFEHIYRHHRRYRITEGAEEIQIR
RVAQRLFKFGKK

Sequences:

>Translated_412_residues
MDFTLPEHLPGVLAEMDAFIEDEIKPLEREHIQYFDQRREHARTDWDNDGIPTREWEDLLAEMRRRADRAGWLRYGLPAS
LGGRDGSNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFPQVIMMERFGTDEQRREWSQALITGERSMAFGLTEPQHGSD
ATWLQTRAERDGDGWVINGAKRFNTGVHRATHDLIFARTSGEPGAAVGITAFLVPTEAPGFTVPYYWWTFNMPTDHGEVE
LTDVRVPADAVLGEVDRGLEVAQTFLHENRIRQAASSLGAAQYCIDRAAEYAGSRTVFGKPLSVNQAVQWPLAELQTEAQ
MVRLLVQYAAWHLDRDHHMEVSDKVSMANYRANRLVCDAADRAMQIFGGLGYSRHEPFEHIYRHHRRYRITEGAEEIQIR
RVAQRLFKFGKK
>Mature_412_residues
MDFTLPEHLPGVLAEMDAFIEDEIKPLEREHIQYFDQRREHARTDWDNDGIPTREWEDLLAEMRRRADRAGWLRYGLPAS
LGGRDGSNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFPQVIMMERFGTDEQRREWSQALITGERSMAFGLTEPQHGSD
ATWLQTRAERDGDGWVINGAKRFNTGVHRATHDLIFARTSGEPGAAVGITAFLVPTEAPGFTVPYYWWTFNMPTDHGEVE
LTDVRVPADAVLGEVDRGLEVAQTFLHENRIRQAASSLGAAQYCIDRAAEYAGSRTVFGKPLSVNQAVQWPLAELQTEAQ
MVRLLVQYAAWHLDRDHHMEVSDKVSMANYRANRLVCDAADRAMQIFGGLGYSRHEPFEHIYRHHRRYRITEGAEEIQIR
RVAQRLFKFGKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=339, Percent_Identity=31.858407079646, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI187960098, Length=341, Percent_Identity=31.3782991202346, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4557231, Length=341, Percent_Identity=31.3782991202346, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI7656849, Length=399, Percent_Identity=27.5689223057644, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI38505218, Length=401, Percent_Identity=27.6807980049875, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4501859, Length=328, Percent_Identity=29.5731707317073, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI21361497, Length=407, Percent_Identity=27.5184275184275, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=27.4869109947644, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI76496475, Length=399, Percent_Identity=27.0676691729323, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI4557235, Length=399, Percent_Identity=27.0676691729323, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI211971008, Length=291, Percent_Identity=28.8659793814433, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI48976061, Length=291, Percent_Identity=28.8659793814433, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI226958412, Length=287, Percent_Identity=29.2682926829268, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI226958414, Length=287, Percent_Identity=29.2682926829268, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI7669494, Length=284, Percent_Identity=29.5774647887324, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4503943, Length=263, Percent_Identity=30.7984790874525, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI87081958, Length=411, Percent_Identity=29.1970802919708, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786223, Length=333, Percent_Identity=25.8258258258258, Blast_Score=94, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=350, Percent_Identity=31.1428571428571, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=349, Percent_Identity=31.5186246418338, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=412, Percent_Identity=27.4271844660194, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17533517, Length=402, Percent_Identity=28.8557213930348, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17508101, Length=403, Percent_Identity=28.5359801488834, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17506239, Length=396, Percent_Identity=27.5252525252525, Blast_Score=130, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71985184, Length=383, Percent_Identity=28.4595300261097, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17538396, Length=400, Percent_Identity=27.25, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17505929, Length=404, Percent_Identity=26.7326732673267, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17562446, Length=335, Percent_Identity=28.6567164179104, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=297, Percent_Identity=27.9461279461279, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI71990804, Length=286, Percent_Identity=29.7202797202797, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71985192, Length=343, Percent_Identity=26.8221574344023, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=234, Percent_Identity=30.7692307692308, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17534353, Length=262, Percent_Identity=26.7175572519084, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71982178, Length=180, Percent_Identity=31.6666666666667, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=25.6198347107438, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=30.9895833333333, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24646207, Length=290, Percent_Identity=33.1034482758621, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21356377, Length=345, Percent_Identity=29.8550724637681, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24666513, Length=352, Percent_Identity=31.8181818181818, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355753, Length=383, Percent_Identity=28.7206266318538, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281363737, Length=404, Percent_Identity=28.4653465346535, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI19920834, Length=264, Percent_Identity=31.0606060606061, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 46988; Mature: 46988

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFTLPEHLPGVLAEMDAFIEDEIKPLEREHIQYFDQRREHARTDWDNDGIPTREWEDLL
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AEMRRRADRAGWLRYGLPASLGGRDGSNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFP
HHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCH
QVIMMERFGTDEQRREWSQALITGERSMAFGLTEPQHGSDATWLQTRAERDGDGWVINGA
HHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCEEECCH
KRFNTGVHRATHDLIFARTSGEPGAAVGITAFLVPTEAPGFTVPYYWWTFNMPTDHGEVE
HHHCCHHHHHHHHEEEEECCCCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCCEE
LTDVRVPADAVLGEVDRGLEVAQTFLHENRIRQAASSLGAAQYCIDRAAEYAGSRTVFGK
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PLSVNQAVQWPLAELQTEAQMVRLLVQYAAWHLDRDHHMEVSDKVSMANYRANRLVCDAA
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEEEHHH
DRAMQIFGGLGYSRHEPFEHIYRHHRRYRITEGAEEIQIRRVAQRLFKFGKK
HHHHHHHHCCCCCCCCHHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFTLPEHLPGVLAEMDAFIEDEIKPLEREHIQYFDQRREHARTDWDNDGIPTREWEDLL
CCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
AEMRRRADRAGWLRYGLPASLGGRDGSNVDMAVIREHLAHKGLGLHNDLQNESSIVGNFP
HHHHHHHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCH
QVIMMERFGTDEQRREWSQALITGERSMAFGLTEPQHGSDATWLQTRAERDGDGWVINGA
HHHHHHHCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCCCHHHHHHHCCCCCCEEECCH
KRFNTGVHRATHDLIFARTSGEPGAAVGITAFLVPTEAPGFTVPYYWWTFNMPTDHGEVE
HHHCCHHHHHHHHEEEEECCCCCCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCCEE
LTDVRVPADAVLGEVDRGLEVAQTFLHENRIRQAASSLGAAQYCIDRAAEYAGSRTVFGK
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PLSVNQAVQWPLAELQTEAQMVRLLVQYAAWHLDRDHHMEVSDKVSMANYRANRLVCDAA
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCEEEEHHH
DRAMQIFGGLGYSRHEPFEHIYRHHRRYRITEGAEEIQIRRVAQRLFKFGKK
HHHHHHHHCCCCCCCCHHHHHHHHHHCEECCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]