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The map label for this gene is tfdA [H]

Identifier: 41409233

GI number: 41409233

Start: 3488893

End: 3489738

Strand: Reverse

Name: tfdA [H]

Synonym: MAP3135c

Alternate gene names: 41409233

Gene position: 3489738-3488893 (Counterclockwise)

Preceding gene: 41409234

Following gene: 41409232

Centisome position: 72.25

GC content: 68.09

Gene sequence:

>846_bases
ATGAGTCTGCTCACCATCACCAAACTCACCGACTCGGTCGGCGCCGAAGTCACCGGCCTGGATCCGGCCGCCCTGGCACA
CGACGACTCGGTGGGTGAGGCGGTGCTGGATGCCTTGGAAGACAACGGGGTTCTGGTCTTCCGCGGCTTGTATCTCGACC
CGGCGGCGCAGGTCGCCTTCTGCGGCCGCCTCGGCGAGGTCGATCACTCCTCCGACGGCCACCACCCGGTGCCCGGCATC
TACCCGATCACGCTGGACAAGTCCAAGAACGCCTCCGCGGCCTACCTGAAGGCGACCTTCGACTGGCACATCGACGGCTG
CACACCGCTGGGCGACGAGTGTCCGCAGAAGGCCACCGTGCTGTCGGCGGTCCGGGTCGCCGAGCGGGGCGGCGAAACCG
AATTCGCGAATTCCTACGCTGCGTACGACGCACTGACCGACGACGAGAAACGGCGGTTCGGCGCATTGCGGGTGGTGCAC
TCGCTGGAGGCCTCCCAGCGCCGGGTCTATCCCGATCCGTCACCGGAACTCATGGCGCGCTGGCGGTCTCGGCGCACGCA
TGAACACCCGCTGGTGTGGACGCATCGCAGCGGGCGCAAATCGCTGGTGCTGGGTGCCTCCGCGGATTACGTCGTGGGCA
TGGACGTCGACGAGGGACGCGCCCTGCTCGAGGAACTGCTGCAGCGCGCCACGGTGCCCGAACGGGTCTACCGCCACGGC
TGGTCGATCGGCGACACCGTCATCTGGGACAACCGTGGGGTGCTGCACCGGGCGGCGCCCTACGACCCGGACTCGTCGCG
AGAGATGCTGCGCACCACCGTGCGCGGTGACGAGCCGATCCAATAG

Upstream 100 bases:

>100_bases
CCCGGTCGACGCCGCCGACGCGGTCATGATCCGGACCGGCGGCCCGGTGCCCTGACCCGGCGGCCGAGACCGTCCAACCC
TGCTGCGGAAAGGAGCGGCC

Downstream 100 bases:

>100_bases
CATGGCCGCGTCCGACCGGCATCCGCAGCGCCTGACACCGCTGCCCGCCGACGAGTGGGACGAGGACACCCGCGCGGCGC
TGGCCTCGCTGATCCCCGCC

Product: hypothetical protein

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: 2,4-D dioxygenase [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRGLYLDPAAQVAFCGRLGEVDHSSDGHHPVPGI
YPITLDKSKNASAAYLKATFDWHIDGCTPLGDECPQKATVLSAVRVAERGGETEFANSYAAYDALTDDEKRRFGALRVVH
SLEASQRRVYPDPSPELMARWRSRRTHEHPLVWTHRSGRKSLVLGASADYVVGMDVDEGRALLEELLQRATVPERVYRHG
WSIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTVRGDEPIQ

Sequences:

>Translated_281_residues
MSLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRGLYLDPAAQVAFCGRLGEVDHSSDGHHPVPGI
YPITLDKSKNASAAYLKATFDWHIDGCTPLGDECPQKATVLSAVRVAERGGETEFANSYAAYDALTDDEKRRFGALRVVH
SLEASQRRVYPDPSPELMARWRSRRTHEHPLVWTHRSGRKSLVLGASADYVVGMDVDEGRALLEELLQRATVPERVYRHG
WSIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTVRGDEPIQ
>Mature_280_residues
SLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRGLYLDPAAQVAFCGRLGEVDHSSDGHHPVPGIY
PITLDKSKNASAAYLKATFDWHIDGCTPLGDECPQKATVLSAVRVAERGGETEFANSYAAYDALTDDEKRRFGALRVVHS
LEASQRRVYPDPSPELMARWRSRRTHEHPLVWTHRSGRKSLVLGASADYVVGMDVDEGRALLEELLQRATVPERVYRHGW
SIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTVRGDEPIQ

Specific function: Involved in degradation of the herbicide 2,4- dichlorophenoxyacetic acid (2,4-D). Is also able to degrade 2- methyl-4-chlorophenoxyacetic acid and 3-chlorobenzoic acid [H]

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=292, Percent_Identity=29.7945205479452, Blast_Score=88, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322971, Length=297, Percent_Identity=26.2626262626263, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 30925; Mature: 30794

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRGLYLDPAAQVAF
CCEEEEEHHHHHHCCEEECCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCHHHHHH
CGRLGEVDHSSDGHHPVPGIYPITLDKSKNASAAYLKATFDWHIDGCTPLGDECPQKATV
HHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHH
LSAVRVAERGGETEFANSYAAYDALTDDEKRRFGALRVVHSLEASQRRVYPDPSPELMAR
HHHHHHHHCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
WRSRRTHEHPLVWTHRSGRKSLVLGASADYVVGMDVDEGRALLEELLQRATVPERVYRHG
HHHCCCCCCCEEEEECCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHCC
WSIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTVRGDEPIQ
CCCCCEEEECCCCCEECCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRGLYLDPAAQVAF
CEEEEEHHHHHHCCEEECCCHHHHCCCCHHHHHHHHHHCCCCEEEEEEEEECCHHHHHH
CGRLGEVDHSSDGHHPVPGIYPITLDKSKNASAAYLKATFDWHIDGCTPLGDECPQKATV
HHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCCCCCCCCHHHHH
LSAVRVAERGGETEFANSYAAYDALTDDEKRRFGALRVVHSLEASQRRVYPDPSPELMAR
HHHHHHHHCCCCCHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
WRSRRTHEHPLVWTHRSGRKSLVLGASADYVVGMDVDEGRALLEELLQRATVPERVYRHG
HHHCCCCCCCEEEEECCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHCC
WSIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTVRGDEPIQ
CCCCCEEEECCCCCEECCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8779585 [H]