| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41409223
GI number: 41409223
Start: 3476267
End: 3477073
Strand: Reverse
Name: fabG [H]
Synonym: MAP3125c
Alternate gene names: 41409223
Gene position: 3477073-3476267 (Counterclockwise)
Preceding gene: 41409224
Following gene: 41409222
Centisome position: 71.99
GC content: 71.87
Gene sequence:
>807_bases ATGAGCGGGCAGCGGTGCGACGGGATGGTGGCGCTGGTCACCGGGAGCAGCCGGGGGCTGGGCAGGGCGATCGCCGGGCG GCTGGCCGCACGCGGCGCCACCGTGGCGCTGACCGCCCGCACCCTGGACCCCGACCCGAAATATCAGGGGTCGCTGCGCC AGACCCGCGACGAGATCCTGGCCGCCGGCGGGAAAGCCGTTGCGGTGCAGGCGGACCTGTCGCAACCCGACGAACGCGAG CGGCTGTTCGCCGAGGTGGTCGACACAGTCGGCGCGCCGGACATCCTGGTCAACAACGCCGCGGTCACCTTCCTGCGGCC GCTGGACGGGTTCCCGCAACGGCGCGCCCGGCTGATGATGGAGATGCACGTGCTCGGGCCGCTGCACCTGTGCCAGCTGG CGATCCCCGCGATGCGCGAGCGCGGCCGCGGCTGGATCGTGAACCTGACCTCGGTGGGCGGCGACCTGCCGCCCGGCCCG CCGTTCTCCGAATTCGACCGGACCGCCGGCTTCGGCATCTACGGCACGGCCAAGGCCGCCCTGAACCGGTTGACGAAAAG CCTTGCGGCCGAACTGTACGACGACGGGATCGCCGTCAACGCCGCCGCACCGTCCAACCCCGTCGCCACGCCCGGCGCCG GCACCCTGGATCTGGCCAAGACCGACACCGAGGACATCGCGCTGATCACCGAGACGGTGTTCCGGTTGTGCACCGGTGAT CCGAAGACGTTGACCGGTCGCATCGCGCACACCCAACCCTTCCTCGCCGAGGTCGGCTGGCCCGGCACCGGCCCGCCGGT CACATGA
Upstream 100 bases:
>100_bases GGCGACGGCGATCGACGGCTAGCCGCTTTTCCCGCACCGGCGATAATGGCATTCTCTGATGCGGAGAAGCCATTTCCGAC CGTCACCGAGGAGGACGACG
Downstream 100 bases:
>100_bases GCAGCGCCGAGCCGGACCTGGACGTCCTGCGCGGCCGGCTGGCCGGCGCGGGTATCACCGACGTCACCCCGCTGTCCGGC GGCGCGTCCGGCCTCACCTT
Product: hypothetical protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 268; Mature: 267
Protein sequence:
>268_residues MSGQRCDGMVALVTGSSRGLGRAIAGRLAARGATVALTARTLDPDPKYQGSLRQTRDEILAAGGKAVAVQADLSQPDERE RLFAEVVDTVGAPDILVNNAAVTFLRPLDGFPQRRARLMMEMHVLGPLHLCQLAIPAMRERGRGWIVNLTSVGGDLPPGP PFSEFDRTAGFGIYGTAKAALNRLTKSLAAELYDDGIAVNAAAPSNPVATPGAGTLDLAKTDTEDIALITETVFRLCTGD PKTLTGRIAHTQPFLAEVGWPGTGPPVT
Sequences:
>Translated_268_residues MSGQRCDGMVALVTGSSRGLGRAIAGRLAARGATVALTARTLDPDPKYQGSLRQTRDEILAAGGKAVAVQADLSQPDERE RLFAEVVDTVGAPDILVNNAAVTFLRPLDGFPQRRARLMMEMHVLGPLHLCQLAIPAMRERGRGWIVNLTSVGGDLPPGP PFSEFDRTAGFGIYGTAKAALNRLTKSLAAELYDDGIAVNAAAPSNPVATPGAGTLDLAKTDTEDIALITETVFRLCTGD PKTLTGRIAHTQPFLAEVGWPGTGPPVT >Mature_267_residues SGQRCDGMVALVTGSSRGLGRAIAGRLAARGATVALTARTLDPDPKYQGSLRQTRDEILAAGGKAVAVQADLSQPDERER LFAEVVDTVGAPDILVNNAAVTFLRPLDGFPQRRARLMMEMHVLGPLHLCQLAIPAMRERGRGWIVNLTSVGGDLPPGPP FSEFDRTAGFGIYGTAKAALNRLTKSLAAELYDDGIAVNAAAPSNPVATPGAGTLDLAKTDTEDIALITETVFRLCTGDP KTLTGRIAHTQPFLAEVGWPGTGPPVT
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254986, Length=267, Percent_Identity=27.7153558052434, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI32483357, Length=196, Percent_Identity=33.6734693877551, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI19923817, Length=207, Percent_Identity=29.4685990338164, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI209862901, Length=210, Percent_Identity=32.3809523809524, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI19923983, Length=210, Percent_Identity=32.3809523809524, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI4504505, Length=203, Percent_Identity=31.5270935960591, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=32.1243523316062, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI31542939, Length=205, Percent_Identity=27.8048780487805, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI5031737, Length=196, Percent_Identity=28.0612244897959, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI40254992, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI223718074, Length=195, Percent_Identity=30.2564102564103, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787335, Length=198, Percent_Identity=33.8383838383838, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI87082100, Length=209, Percent_Identity=32.5358851674641, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1787905, Length=200, Percent_Identity=31, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI2367175, Length=203, Percent_Identity=33.9901477832512, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1788459, Length=209, Percent_Identity=32.0574162679426, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787820, Length=197, Percent_Identity=26.3959390862944, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=25.6198347107438, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI87082160, Length=201, Percent_Identity=26.865671641791, Blast_Score=61, Evalue=6e-11, Organism=Caenorhabditis elegans, GI86565303, Length=210, Percent_Identity=33.8095238095238, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17531453, Length=240, Percent_Identity=31.6666666666667, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562906, Length=207, Percent_Identity=32.8502415458937, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560332, Length=207, Percent_Identity=32.3671497584541, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI71982365, Length=203, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538486, Length=205, Percent_Identity=32.1951219512195, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17562908, Length=215, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI17560220, Length=207, Percent_Identity=32.3671497584541, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=29.3233082706767, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI193204405, Length=207, Percent_Identity=32.8502415458937, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17559104, Length=202, Percent_Identity=31.1881188118812, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17560150, Length=236, Percent_Identity=29.6610169491525, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17558628, Length=255, Percent_Identity=24.7058823529412, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71997099, Length=216, Percent_Identity=32.8703703703704, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560676, Length=196, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17551412, Length=208, Percent_Identity=31.7307692307692, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17555612, Length=214, Percent_Identity=33.1775700934579, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538480, Length=216, Percent_Identity=31.4814814814815, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=26.7175572519084, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17562990, Length=227, Percent_Identity=28.6343612334802, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17565030, Length=209, Percent_Identity=30.622009569378, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17508895, Length=184, Percent_Identity=26.6304347826087, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17564282, Length=151, Percent_Identity=29.1390728476821, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17568967, Length=209, Percent_Identity=31.5789473684211, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17536025, Length=209, Percent_Identity=29.6650717703349, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17544670, Length=216, Percent_Identity=27.7777777777778, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561272, Length=210, Percent_Identity=32.8571428571429, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17567345, Length=191, Percent_Identity=28.7958115183246, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=29.9492385786802, Blast_Score=67, Evalue=4e-12, Organism=Drosophila melanogaster, GI21357673, Length=245, Percent_Identity=27.3469387755102, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21355319, Length=205, Percent_Identity=31.219512195122, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24640492, Length=148, Percent_Identity=33.7837837837838, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=29.0816326530612, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24644339, Length=197, Percent_Identity=26.9035532994924, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI18859837, Length=203, Percent_Identity=30.5418719211823, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24580925, Length=205, Percent_Identity=30.2439024390244, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24649181, Length=201, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 28164; Mature: 28032
Theoretical pI: Translated: 6.78; Mature: 6.78
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGQRCDGMVALVTGSSRGLGRAIAGRLAARGATVALTARTLDPDPKYQGSLRQTRDEIL CCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHH AAGGKAVAVQADLSQPDERERLFAEVVDTVGAPDILVNNAAVTFLRPLDGFPQRRARLMM HCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCCHHHHHHHHH EMHVLGPLHLCQLAIPAMRERGRGWIVNLTSVGGDLPPGPPFSEFDRTAGFGIYGTAKAA HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCCEEHHHHH LNRLTKSLAAELYDDGIAVNAAAPSNPVATPGAGTLDLAKTDTEDIALITETVFRLCTGD HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCC PKTLTGRIAHTQPFLAEVGWPGTGPPVT CCCEEEEECCCCCHHHHCCCCCCCCCCC >Mature Secondary Structure SGQRCDGMVALVTGSSRGLGRAIAGRLAARGATVALTARTLDPDPKYQGSLRQTRDEIL CCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHHHH AAGGKAVAVQADLSQPDERERLFAEVVDTVGAPDILVNNAAVTFLRPLDGFPQRRARLMM HCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCCCHHHHHHHHH EMHVLGPLHLCQLAIPAMRERGRGWIVNLTSVGGDLPPGPPFSEFDRTAGFGIYGTAKAA HHHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHCCCCCCEEHHHHH LNRLTKSLAAELYDDGIAVNAAAPSNPVATPGAGTLDLAKTDTEDIALITETVFRLCTGD HHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCC PKTLTGRIAHTQPFLAEVGWPGTGPPVT CCCEEEEECCCCCHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA