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The map label for this gene is dnaK [H]

Identifier: 41409217

GI number: 41409217

Start: 3469366

End: 3470883

Strand: Direct

Name: dnaK [H]

Synonym: MAP3119

Alternate gene names: 41409217

Gene position: 3469366-3470883 (Clockwise)

Preceding gene: 41409216

Following gene: 41409219

Centisome position: 71.83

GC content: 71.08

Gene sequence:

>1518_bases
ATGAGAGTCGGAATCGACTTCGGCACAACCCACACCGTCGTCGCCGCCGTCGACCGCGGCAACTATCCGGTCGTCTTCTT
CGACGGCATGGACGCGTGGCCGTCGATCATCGCCGCCAACGCCGCCGGGGAGCTGCGCTACGGCGCGGACGCGGCCGCCG
TGCGCCACGACCCGTCGTGGTCGGTGCTGCGCTCGTTCAAACGTCTGCTCAACGACGCCGGGCCGCAGACCCGGGTCAAG
CTGGCCGGCCGTGACTACCGGCTGGCCGAACTGCTGACCGGTTTTCTGGCGCGGCTGAAAACCGATCTGCAGCAGCACTC
CAACGCCACCGTGGCCCCCGGGGAGCCCATCGAGGCCGCGATCAGCGTGCCGGCCAACGCCTCCAGCGCCCAGCGGCTGC
TGACCCTGGACGCCTACGTGGCCGCCGGTTTCCACGTCGTCGCCCTGCTCAACGAGCCGTCCGCGGCGAGCCTGGAATAC
GCGCATCGGTACCGCTCCACCATCACCGCCAAACGGGAGTACGTGCTCGTCTACGACCTCGGCGGCGGAACCTTCGACGC
GTCGCTGCTGAAGATGACCGGGCACTCCAACGAGGTGGTGGTCAGCGAGGGCATCCAGCGGCTCGGCGGCGACGACTTCG
ACGAGGCGATCGTCGAGCTGGTGCGGGCCGGTGCGGACCTGCCCGGCCTCGACGCCGCCGGCCGCGCGTTGCTGGCCGAG
GAATGCGCCGCCCGCAAGGAGGCGGTCGGGCCGCAGACCCGCCGCTTCCTGGTTGACCTGTCGCCGTTCGACCGGCCCCC
GTTCTCCTGTCCGGTCGACGACGTGTACGCGGCGTGCGCCCCGCTGGTCGATCCGACGATGCGGCTGCTGGAGCGGGTGC
TGCGCGACCCGAGCCGCGGCCGCGCGGACGTGGACTGGTCGGAGGTGGCCGGCATCTATGTGGTCGGCGGGGCCGGCGGC
TTCCCGCTGGTGTCCCGGATGCTGCGCGCCCGGTTCGGGGACAAGCGGGTCAAGCGCTCACCGCACCCGTTCGCCGCGAC
CGCCATCGGGTTGGCGGTGTTCTTGGACAAGGAATCGGGTTTTGCGCTGTCCGAACGCTTTTCGCGGAATTTCGGGGTGT
TCCGGGAGGCGGAGGCGGGCGCCGGGGTGGTGTTCGACCCGATCGTGTGCAAGGACGTGTCGCTGCCGGCCGACGGGCAG
ACCCCGCTGGTGGTCAAGCGGCGATACCGCGCCGCGCACAACATCGGGCACTTCCGGTTCGTGGAGTGCAGCCGGCTGGT
CGACGGGCGACCCGACGGCGACATCACCCCGTATGACCCGGTGCTGTTTCCGTTCGACCCGGCGCTGCGCGACCGCGACG
ACCTGGGCCGCCAGCCGGTCGGCCGGTGGCGGGACGGACCCGACGTCGAGGAGCGCTACGTGATCGCGCCCAGCGGTGCG
GTGGAGGTGACGTTGACGACGCAGCCGGCCGGCTTCGAACGCACCTTCCGGCTGGAGCGGTGCGCATCGGCGAGCTGA

Upstream 100 bases:

>100_bases
TCTGATCGCCACCGCCGCCGAGCGGGAGGTGCAACGGCGTTGGGACGCGCCCGGCGGAAAGGTCGTGCCCAAGCCGGCGC
CGCGGTCCTAAACTTGCGCG

Downstream 100 bases:

>100_bases
GCCGCGGCCGCTAGTTGCGGACCGCGGGCAGCACGGCCTGCTCCCAGGCCGCGAAGAACCCGTCCATGTCCGGGCCGATC
TGCTGCACGTAGACCTCGTC

Product: hypothetical protein

Products: NA

Alternate protein names: HSP70; Heat shock 70 kDa protein; Heat shock protein 70 [H]

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MRVGIDFGTTHTVVAAVDRGNYPVVFFDGMDAWPSIIAANAAGELRYGADAAAVRHDPSWSVLRSFKRLLNDAGPQTRVK
LAGRDYRLAELLTGFLARLKTDLQQHSNATVAPGEPIEAAISVPANASSAQRLLTLDAYVAAGFHVVALLNEPSAASLEY
AHRYRSTITAKREYVLVYDLGGGTFDASLLKMTGHSNEVVVSEGIQRLGGDDFDEAIVELVRAGADLPGLDAAGRALLAE
ECAARKEAVGPQTRRFLVDLSPFDRPPFSCPVDDVYAACAPLVDPTMRLLERVLRDPSRGRADVDWSEVAGIYVVGGAGG
FPLVSRMLRARFGDKRVKRSPHPFAATAIGLAVFLDKESGFALSERFSRNFGVFREAEAGAGVVFDPIVCKDVSLPADGQ
TPLVVKRRYRAAHNIGHFRFVECSRLVDGRPDGDITPYDPVLFPFDPALRDRDDLGRQPVGRWRDGPDVEERYVIAPSGA
VEVTLTTQPAGFERTFRLERCASAS

Sequences:

>Translated_505_residues
MRVGIDFGTTHTVVAAVDRGNYPVVFFDGMDAWPSIIAANAAGELRYGADAAAVRHDPSWSVLRSFKRLLNDAGPQTRVK
LAGRDYRLAELLTGFLARLKTDLQQHSNATVAPGEPIEAAISVPANASSAQRLLTLDAYVAAGFHVVALLNEPSAASLEY
AHRYRSTITAKREYVLVYDLGGGTFDASLLKMTGHSNEVVVSEGIQRLGGDDFDEAIVELVRAGADLPGLDAAGRALLAE
ECAARKEAVGPQTRRFLVDLSPFDRPPFSCPVDDVYAACAPLVDPTMRLLERVLRDPSRGRADVDWSEVAGIYVVGGAGG
FPLVSRMLRARFGDKRVKRSPHPFAATAIGLAVFLDKESGFALSERFSRNFGVFREAEAGAGVVFDPIVCKDVSLPADGQ
TPLVVKRRYRAAHNIGHFRFVECSRLVDGRPDGDITPYDPVLFPFDPALRDRDDLGRQPVGRWRDGPDVEERYVIAPSGA
VEVTLTTQPAGFERTFRLERCASAS
>Mature_505_residues
MRVGIDFGTTHTVVAAVDRGNYPVVFFDGMDAWPSIIAANAAGELRYGADAAAVRHDPSWSVLRSFKRLLNDAGPQTRVK
LAGRDYRLAELLTGFLARLKTDLQQHSNATVAPGEPIEAAISVPANASSAQRLLTLDAYVAAGFHVVALLNEPSAASLEY
AHRYRSTITAKREYVLVYDLGGGTFDASLLKMTGHSNEVVVSEGIQRLGGDDFDEAIVELVRAGADLPGLDAAGRALLAE
ECAARKEAVGPQTRRFLVDLSPFDRPPFSCPVDDVYAACAPLVDPTMRLLERVLRDPSRGRADVDWSEVAGIYVVGGAGG
FPLVSRMLRARFGDKRVKRSPHPFAATAIGLAVFLDKESGFALSERFSRNFGVFREAEAGAGVVFDPIVCKDVSLPADGQ
TPLVVKRRYRAAHNIGHFRFVECSRLVDGRPDGDITPYDPVLFPFDPALRDRDDLGRQPVGRWRDGPDVEERYVIAPSGA
VEVTLTTQPAGFERTFRLERCASAS

Specific function: Acts as a chaperone [H]

COG id: COG0443

COG function: function code O; Molecular chaperone

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 70 family [H]

Homologues:

Organism=Homo sapiens, GI34419635, Length=386, Percent_Identity=29.5336787564767, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI16507237, Length=384, Percent_Identity=29.4270833333333, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI124256496, Length=383, Percent_Identity=28.4595300261097, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI5729877, Length=384, Percent_Identity=29.1666666666667, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI24234686, Length=383, Percent_Identity=28.4595300261097, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI167466173, Length=384, Percent_Identity=28.3854166666667, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI194248072, Length=384, Percent_Identity=28.3854166666667, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI13676857, Length=382, Percent_Identity=26.4397905759162, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI24234688, Length=472, Percent_Identity=26.0593220338983, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI48928056, Length=125, Percent_Identity=36.8, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786870, Length=406, Percent_Identity=28.3251231527094, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788875, Length=376, Percent_Identity=31.1170212765957, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1786196, Length=390, Percent_Identity=29.7435897435897, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17541098, Length=390, Percent_Identity=29.2307692307692, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17534771, Length=386, Percent_Identity=27.979274611399, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17568549, Length=385, Percent_Identity=27.2727272727273, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17507981, Length=386, Percent_Identity=27.4611398963731, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17534015, Length=386, Percent_Identity=27.2020725388601, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17534013, Length=386, Percent_Identity=27.2020725388601, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562024, Length=480, Percent_Identity=27.5, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71984444, Length=398, Percent_Identity=26.6331658291457, Blast_Score=97, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6319314, Length=384, Percent_Identity=29.6875, Blast_Score=123, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6323004, Length=386, Percent_Identity=29.7927461139896, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322426, Length=440, Percent_Identity=28.1818181818182, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6319972, Length=383, Percent_Identity=30.2872062663185, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324120, Length=381, Percent_Identity=29.6587926509186, Blast_Score=111, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320950, Length=385, Percent_Identity=29.6103896103896, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319396, Length=385, Percent_Identity=28.3116883116883, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6320805, Length=389, Percent_Identity=27.2493573264781, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322505, Length=387, Percent_Identity=28.1653746770026, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323401, Length=402, Percent_Identity=26.1194029850746, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24647034, Length=384, Percent_Identity=28.90625, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24647038, Length=384, Percent_Identity=28.90625, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24647036, Length=384, Percent_Identity=28.90625, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17737967, Length=384, Percent_Identity=28.90625, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571721, Length=384, Percent_Identity=28.90625, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571719, Length=384, Percent_Identity=28.90625, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI17647515, Length=382, Percent_Identity=28.0104712041885, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641406, Length=386, Percent_Identity=29.0155440414508, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24641408, Length=386, Percent_Identity=29.0155440414508, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24641402, Length=386, Percent_Identity=29.0155440414508, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24641404, Length=386, Percent_Identity=29.0155440414508, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17738165, Length=385, Percent_Identity=29.6103896103896, Blast_Score=112, Evalue=9e-25,
Organism=Drosophila melanogaster, GI17737941, Length=393, Percent_Identity=28.2442748091603, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24646324, Length=386, Percent_Identity=29.2746113989637, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646322, Length=386, Percent_Identity=29.2746113989637, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646318, Length=386, Percent_Identity=29.2746113989637, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646137, Length=386, Percent_Identity=29.2746113989637, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646135, Length=386, Percent_Identity=29.2746113989637, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571678, Length=386, Percent_Identity=29.2746113989637, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24663992, Length=297, Percent_Identity=28.956228956229, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24663988, Length=297, Percent_Identity=28.956228956229, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24653595, Length=385, Percent_Identity=26.2337662337662, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012725
- InterPro:   IPR018181
- InterPro:   IPR001023
- InterPro:   IPR013126 [H]

Pfam domain/function: PF00012 HSP70 [H]

EC number: NA

Molecular weight: Translated: 54814; Mature: 54814

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00329 HSP70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGIDFGTTHTVVAAVDRGNYPVVFFDGMDAWPSIIAANAAGELRYGADAAAVRHDPSW
CEEECCCCCCEEEEEEEECCCCCEEEECCCCCCHHHEEECCCCCCCCCCCHHHEECCCCH
SVLRSFKRLLNDAGPQTRVKLAGRDYRLAELLTGFLARLKTDLQQHSNATVAPGEPIEAA
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
ISVPANASSAQRLLTLDAYVAAGFHVVALLNEPSAASLEYAHRYRSTITAKREYVLVYDL
EECCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEC
GGGTFDASLLKMTGHSNEVVVSEGIQRLGGDDFDEAIVELVRAGADLPGLDAAGRALLAE
CCCCCCHHHHEECCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ECAARKEAVGPQTRRFLVDLSPFDRPPFSCPVDDVYAACAPLVDPTMRLLERVLRDPSRG
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
RADVDWSEVAGIYVVGGAGGFPLVSRMLRARFGDKRVKRSPHPFAATAIGLAVFLDKESG
CCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHEEEEEEEECCCC
FALSERFSRNFGVFREAEAGAGVVFDPIVCKDVSLPADGQTPLVVKRRYRAAHNIGHFRF
CHHHHHHHCCCCCEEECCCCCCEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
VECSRLVDGRPDGDITPYDPVLFPFDPALRDRDDLGRQPVGRWRDGPDVEERYVIAPSGA
EEHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCE
VEVTLTTQPAGFERTFRLERCASAS
EEEEEECCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MRVGIDFGTTHTVVAAVDRGNYPVVFFDGMDAWPSIIAANAAGELRYGADAAAVRHDPSW
CEEECCCCCCEEEEEEEECCCCCEEEECCCCCCHHHEEECCCCCCCCCCCHHHEECCCCH
SVLRSFKRLLNDAGPQTRVKLAGRDYRLAELLTGFLARLKTDLQQHSNATVAPGEPIEAA
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
ISVPANASSAQRLLTLDAYVAAGFHVVALLNEPSAASLEYAHRYRSTITAKREYVLVYDL
EECCCCCCCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEC
GGGTFDASLLKMTGHSNEVVVSEGIQRLGGDDFDEAIVELVRAGADLPGLDAAGRALLAE
CCCCCCHHHHEECCCCCCEEHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ECAARKEAVGPQTRRFLVDLSPFDRPPFSCPVDDVYAACAPLVDPTMRLLERVLRDPSRG
HHHHHHHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
RADVDWSEVAGIYVVGGAGGFPLVSRMLRARFGDKRVKRSPHPFAATAIGLAVFLDKESG
CCCCCHHHCCCEEEECCCCCHHHHHHHHHHHHCCHHHCCCCCCHHHHHEEEEEEEECCCC
FALSERFSRNFGVFREAEAGAGVVFDPIVCKDVSLPADGQTPLVVKRRYRAAHNIGHFRF
CHHHHHHHCCCCCEEECCCCCCEEECCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEE
VECSRLVDGRPDGDITPYDPVLFPFDPALRDRDDLGRQPVGRWRDGPDVEERYVIAPSGA
EEHHHHHCCCCCCCCCCCCCEEECCCCCCCCHHHCCCCCCCCCCCCCCCCCEEEECCCCE
VEVTLTTQPAGFERTFRLERCASAS
EEEEEECCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA