| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is ephD [H]
Identifier: 41409205
GI number: 41409205
Start: 3453393
End: 3454325
Strand: Reverse
Name: ephD [H]
Synonym: MAP3107c
Alternate gene names: 41409205
Gene position: 3454325-3453393 (Counterclockwise)
Preceding gene: 41409206
Following gene: 41409202
Centisome position: 71.52
GC content: 71.17
Gene sequence:
>933_bases ATGGCGCAGAAGGCATCCGGGCGGTATTACGCGGGAAAGCGGTGTTTGGTCACCGGCGCGGCCAGCGGCATCGGCCGCGC CACGGCACTGCGGCTCGCCGCCCACGGCGCCGAGCTCTATCTGACCGACCGGGACGGCGACGGCCTGCGGCTCACGGTCG AGGACGCCCGCGCCCTGGGCGCGTCGGTCCCCGAGCATCGCGCGCTGGACATCGCCGACTACGACCAGGTGGCCTCCTTC GCCGCCGACATTCATGCCGCCCACCCGCCGATGGACGTGGTGCTCAACATCGCCGGCGTGTCGGCCTGGGGCACCGTTGA CCGGCTCACCCACGAACAGTGGCGCAAGATGATCGCCATCAACCTGATGGGTCCGATCCATGTCATCGAGACATTCGTCC CGCCCATGGTGGCCGCCGGGCGGGGCGGGCATCTGGCCAACGTGTCCTCGGCGGCCGGGCTGGTCGCGCTGCCCTGGCAC GCCGCCTACAGCGCCAGCAAGTACGGGCTGCGGGGGCTGTCGGAGGTGCTGCGCTTCGACCTGGCCCGGCACCGCATCGG GGTGTCGGTGGTGGTGCCCGGCGCGGTGAACACCCCGCTGGTGAACACGGTGGAGATCGCCGGCGTGGACCGCGACGACC CCGACGTCGCCCGCTGGGTGCGGCGGTTCGCCGGCCATGCGGTGTCGCCGGAAAAGGCCGCCGACAAGATCCTGGCCGGG GTCGCCCGGAACCGGTACCTGATCTACACCTCGCCCGACATCCGGGCGCTGTACGCGTTCAAGAGGCTGGCGTGGTGGCC CTACAGCGTGGTGATGCGTCAGGTGAACGTGATCTTCACCCGCGCGCTGCGGCCCGCGCCGGCGACGCTAGTCCGGCATG ACCAGCTCGAGACGCACCCCGAGCAACCGGACCGGCCGGTCGAGCTCGAATAG
Upstream 100 bases:
>100_bases GATCGCGACCGCCGGGTGGCGGTGCTCGAGCAGTTGTGGCTGCACGCGCTGTGGGCCGGCCGTCCCTAGCGCGGGTGGTA CCGCCGGTATCGTCACCGCC
Downstream 100 bases:
>100_bases ATCCAGCACGCGCAGCGCCGCGGCCACGATGACGTCGCGATCGGTGCTGGGCGCGTCGAGCTTGCGAATTTTGGTGCGGG TGTAGAAGGTGGCCGTGCGC
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 310; Mature: 309
Protein sequence:
>310_residues MAQKASGRYYAGKRCLVTGAASGIGRATALRLAAHGAELYLTDRDGDGLRLTVEDARALGASVPEHRALDIADYDQVASF AADIHAAHPPMDVVLNIAGVSAWGTVDRLTHEQWRKMIAINLMGPIHVIETFVPPMVAAGRGGHLANVSSAAGLVALPWH AAYSASKYGLRGLSEVLRFDLARHRIGVSVVVPGAVNTPLVNTVEIAGVDRDDPDVARWVRRFAGHAVSPEKAADKILAG VARNRYLIYTSPDIRALYAFKRLAWWPYSVVMRQVNVIFTRALRPAPATLVRHDQLETHPEQPDRPVELE
Sequences:
>Translated_310_residues MAQKASGRYYAGKRCLVTGAASGIGRATALRLAAHGAELYLTDRDGDGLRLTVEDARALGASVPEHRALDIADYDQVASF AADIHAAHPPMDVVLNIAGVSAWGTVDRLTHEQWRKMIAINLMGPIHVIETFVPPMVAAGRGGHLANVSSAAGLVALPWH AAYSASKYGLRGLSEVLRFDLARHRIGVSVVVPGAVNTPLVNTVEIAGVDRDDPDVARWVRRFAGHAVSPEKAADKILAG VARNRYLIYTSPDIRALYAFKRLAWWPYSVVMRQVNVIFTRALRPAPATLVRHDQLETHPEQPDRPVELE >Mature_309_residues AQKASGRYYAGKRCLVTGAASGIGRATALRLAAHGAELYLTDRDGDGLRLTVEDARALGASVPEHRALDIADYDQVASFA ADIHAAHPPMDVVLNIAGVSAWGTVDRLTHEQWRKMIAINLMGPIHVIETFVPPMVAAGRGGHLANVSSAAGLVALPWHA AYSASKYGLRGLSEVLRFDLARHRIGVSVVVPGAVNTPLVNTVEIAGVDRDDPDVARWVRRFAGHAVSPEKAADKILAGV ARNRYLIYTSPDIRALYAFKRLAWWPYSVVMRQVNVIFTRALRPAPATLVRHDQLETHPEQPDRPVELE
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=236, Percent_Identity=29.2372881355932, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI142976729, Length=267, Percent_Identity=26.5917602996255, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI4503817, Length=239, Percent_Identity=26.7782426778243, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI15277342, Length=229, Percent_Identity=31.0043668122271, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI31542939, Length=202, Percent_Identity=31.6831683168317, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI7657478, Length=215, Percent_Identity=30.2325581395349, Blast_Score=79, Evalue=7e-15, Organism=Homo sapiens, GI40807363, Length=242, Percent_Identity=26.4462809917355, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI40254992, Length=204, Percent_Identity=29.9019607843137, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI223718074, Length=245, Percent_Identity=30.2040816326531, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI32455239, Length=191, Percent_Identity=32.4607329842932, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI5031765, Length=191, Percent_Identity=32.4607329842932, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7705925, Length=192, Percent_Identity=29.1666666666667, Blast_Score=76, Evalue=4e-14, Organism=Homo sapiens, GI157739938, Length=249, Percent_Identity=22.4899598393574, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI32483357, Length=194, Percent_Identity=30.4123711340206, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI4758504, Length=211, Percent_Identity=30.8056872037915, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI7706318, Length=263, Percent_Identity=24.7148288973384, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI50726952, Length=190, Percent_Identity=31.0526315789474, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI210032110, Length=257, Percent_Identity=22.1789883268482, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI44680136, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI44680133, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI17738292, Length=190, Percent_Identity=27.3684210526316, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI209862901, Length=202, Percent_Identity=29.2079207920792, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI19923983, Length=202, Percent_Identity=29.2079207920792, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI66933014, Length=189, Percent_Identity=31.2169312169312, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=230, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI224922801, Length=169, Percent_Identity=32.5443786982249, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI19743808, Length=199, Percent_Identity=28.643216080402, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1788459, Length=210, Percent_Identity=29.5238095238095, Blast_Score=85, Evalue=6e-18, Organism=Escherichia coli, GI1786812, Length=239, Percent_Identity=28.8702928870293, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1787335, Length=191, Percent_Identity=31.9371727748691, Blast_Score=82, Evalue=7e-17, Organism=Escherichia coli, GI1786701, Length=229, Percent_Identity=28.3842794759825, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI87082100, Length=198, Percent_Identity=32.8282828282828, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1790717, Length=190, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=8e-13, Organism=Escherichia coli, GI2367175, Length=191, Percent_Identity=30.8900523560209, Blast_Score=65, Evalue=8e-12, Organism=Escherichia coli, GI1789208, Length=192, Percent_Identity=24.4791666666667, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1787526, Length=190, Percent_Identity=27.3684210526316, Blast_Score=62, Evalue=7e-11, Organism=Escherichia coli, GI87082160, Length=183, Percent_Identity=26.2295081967213, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI25147288, Length=192, Percent_Identity=29.6875, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=28.8659793814433, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI71997402, Length=191, Percent_Identity=30.3664921465969, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17555706, Length=190, Percent_Identity=29.4736842105263, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI193203117, Length=237, Percent_Identity=24.0506329113924, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17570069, Length=265, Percent_Identity=27.1698113207547, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI193203115, Length=236, Percent_Identity=24.1525423728814, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17560676, Length=225, Percent_Identity=28, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI115534694, Length=222, Percent_Identity=27.027027027027, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI32563809, Length=202, Percent_Identity=29.7029702970297, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17507613, Length=202, Percent_Identity=29.7029702970297, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI72000259, Length=202, Percent_Identity=31.1881188118812, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17562906, Length=199, Percent_Identity=31.6582914572864, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17538486, Length=196, Percent_Identity=29.5918367346939, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562904, Length=252, Percent_Identity=28.1746031746032, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562910, Length=260, Percent_Identity=25, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560150, Length=255, Percent_Identity=29.0196078431373, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17563726, Length=198, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17561402, Length=194, Percent_Identity=26.2886597938144, Blast_Score=66, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17538182, Length=221, Percent_Identity=26.6968325791855, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17531453, Length=215, Percent_Identity=29.7674418604651, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=211, Percent_Identity=29.8578199052133, Blast_Score=75, Evalue=1e-14, Organism=Saccharomyces cerevisiae, GI6319635, Length=290, Percent_Identity=24.8275862068966, Blast_Score=70, Evalue=5e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=27.2251308900524, Blast_Score=63, Evalue=5e-11, Organism=Drosophila melanogaster, GI21358495, Length=253, Percent_Identity=30.0395256916996, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI21356301, Length=252, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=5e-21, Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=31.413612565445, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI21355631, Length=254, Percent_Identity=28.3464566929134, Blast_Score=96, Evalue=4e-20, Organism=Drosophila melanogaster, GI281364892, Length=196, Percent_Identity=29.5918367346939, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI28571526, Length=191, Percent_Identity=28.7958115183246, Blast_Score=85, Evalue=6e-17, Organism=Drosophila melanogaster, GI21357041, Length=191, Percent_Identity=29.3193717277487, Blast_Score=84, Evalue=2e-16, Organism=Drosophila melanogaster, GI24639444, Length=196, Percent_Identity=29.5918367346939, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24581726, Length=275, Percent_Identity=25.8181818181818, Blast_Score=76, Evalue=4e-14, Organism=Drosophila melanogaster, GI24649181, Length=243, Percent_Identity=25.9259259259259, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI24640492, Length=194, Percent_Identity=26.2886597938144, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=31.5, Blast_Score=73, Evalue=3e-13, Organism=Drosophila melanogaster, GI24580925, Length=197, Percent_Identity=27.9187817258883, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24643142, Length=193, Percent_Identity=30.5699481865285, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI18859837, Length=198, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000073 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00561 Abhydrolase_1; PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 33691; Mature: 33560
Theoretical pI: Translated: 9.47; Mature: 9.47
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 1.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAQKASGRYYAGKRCLVTGAASGIGRATALRLAAHGAELYLTDRDGDGLRLTVEDARALG CCCCCCCCEECCCEEEEEECCCCCCHHHHHHHEECCCEEEEEECCCCCEEEEEHHHHHHC ASVPEHRALDIADYDQVASFAADIHAAHPPMDVVLNIAGVSAWGTVDRLTHEQWRKMIAI CCCCCCCEECCCCHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHEEHH NLMGPIHVIETFVPPMVAAGRGGHLANVSSAAGLVALPWHAAYSASKYGLRGLSEVLRFD CCCCHHHHHHHHHCHHHHCCCCCCCCCCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHH LARHRIGVSVVVPGAVNTPLVNTVEIAGVDRDDPDVARWVRRFAGHAVSPEKAADKILAG HHHHHCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH VARNRYLIYTSPDIRALYAFKRLAWWPYSVVMRQVNVIFTRALRPAPATLVRHDQLETHP HHCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCC EQPDRPVELE CCCCCCCCCC >Mature Secondary Structure AQKASGRYYAGKRCLVTGAASGIGRATALRLAAHGAELYLTDRDGDGLRLTVEDARALG CCCCCCCEECCCEEEEEECCCCCCHHHHHHHEECCCEEEEEECCCCCEEEEEHHHHHHC ASVPEHRALDIADYDQVASFAADIHAAHPPMDVVLNIAGVSAWGTVDRLTHEQWRKMIAI CCCCCCCEECCCCHHHHHHHHHHHHCCCCCHHHEEEECCCCCCCHHHHHHHHHHHHEEHH NLMGPIHVIETFVPPMVAAGRGGHLANVSSAAGLVALPWHAAYSASKYGLRGLSEVLRFD CCCCHHHHHHHHHCHHHHCCCCCCCCCCCCCCCEEEECCHHHHCCCHHHHHHHHHHHHHH LARHRIGVSVVVPGAVNTPLVNTVEIAGVDRDDPDVARWVRRFAGHAVSPEKAADKILAG HHHHHCCEEEEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHH VARNRYLIYTSPDIRALYAFKRLAWWPYSVVMRQVNVIFTRALRPAPATLVRHDQLETHP HHCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHCCC EQPDRPVELE CCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12788972 [H]