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The map label for this gene is dinP

Identifier: 41409204

GI number: 41409204

Start: 3452415

End: 3453458

Strand: Direct

Name: dinP

Synonym: MAP3106

Alternate gene names: 41409204

Gene position: 3452415-3453458 (Clockwise)

Preceding gene: 41409203

Following gene: 41409207

Centisome position: 71.48

GC content: 69.64

Gene sequence:

>1044_bases
ATGAGCCCCCGCTGGGTGCTGCACGTCGACCTCGACCAGTTCCTGGCGTCGGTCGAGTTGCGGCGCCGTCCCGAACTGGC
CGGCCTGCCCGTCATCGTCGGCGGCAACGGCGACCCGAACGAACCGCGCAAGGTCGTCACCTGCGCCTCCTACGAGGCAC
GCGAATTCGGCGTCCGCGCGGGCATGCCGCTGCGCGCCGCCGCCCGCCGCTGCCCCCCAGACTCGGGGGTGACGTTCCTG
CCGTCCGACCCGGCCGCCTACGACGCCGCGTCCGACCAGGTGATGGGGCTGCTGCGCGACCTCGGGCATCCGGTGGAGGT
GTGGGGCTGGGACGAGGCCTACCTCGCGGTGACGGCGACGGACCCGATCGAGGTCGCCGAACAGATCCGCGGCGTCATCT
CCTCGGAAACCGGGCTGACCTGTTCGGTCGGCATCAGCGACAACAAGCAGCGCGCCAAGATCGCCACCGGCTTTGCCAAA
CCCGACGGCGTCTTCGTGCTCACCGACGCGAACTGGATGGCGCTGATGGCCGACCGTCCGGTCGACGCGCTGTGGGGTGT
GGGGCCCAAGACCGCGAAAAAGCTTGCGGATCTTCAGATTACGACGGTGTGGCAACTGGCCCACAGTGACGCGGAACTGT
TGACGGCCACCTTCGGGCCGCGCACCGGGTTGTGGCTGCTGCTGCTCGCCAAGGGTGGCGGCGACGACCACGTCAGCGCG
CAACCGTGGGTGCCGCGCTCGCGCAGCCACGTCGTCACGTTTCCCCGGGACCTCACCGATCGCGCCGAAATGGAAACGGC
GGTAACGGATTTGGCCGATCAGGCGGTGGCGGAGGTGCTGACGGCGGGCCGGGTGGTGACCCGGGTCGCGGTGACCGTGC
GCACGGCCACCTTCTACACCCGCACCAAAATTCGCAAGCTCGACGCGCCCAGCACCGATCGCGACGTCATCGTGGCCGCG
GCGCTGCGCGTGCTGGATCTATTCGAGCTCGACCGGCCGGTCCGGTTGCTCGGGGTGCGTCTCGAGCTGGTCATGCCGGA
CTAG

Upstream 100 bases:

>100_bases
ACGCCGACTATGTGCACCACCAGATCAGCGACCACGGCCACACCCTGCAGACGTTGGGCGACGCGTGGGAAAGCCTGGCG
CGCAAGCTGTGCGGTAACTG

Downstream 100 bases:

>100_bases
CGTCGCCGGCGCGGGCCGCAGCGCGCGGGTGAAGATCACGTTCACCTGACGCATCACCACGCTGTAGGGCCACCACGCCA
GCCTCTTGAACGCGTACAGC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSPRWVLHVDLDQFLASVELRRRPELAGLPVIVGGNGDPNEPRKVVTCASYEAREFGVRAGMPLRAAARRCPPDSGVTFL
PSDPAAYDAASDQVMGLLRDLGHPVEVWGWDEAYLAVTATDPIEVAEQIRGVISSETGLTCSVGISDNKQRAKIATGFAK
PDGVFVLTDANWMALMADRPVDALWGVGPKTAKKLADLQITTVWQLAHSDAELLTATFGPRTGLWLLLLAKGGGDDHVSA
QPWVPRSRSHVVTFPRDLTDRAEMETAVTDLADQAVAEVLTAGRVVTRVAVTVRTATFYTRTKIRKLDAPSTDRDVIVAA
ALRVLDLFELDRPVRLLGVRLELVMPD

Sequences:

>Translated_347_residues
MSPRWVLHVDLDQFLASVELRRRPELAGLPVIVGGNGDPNEPRKVVTCASYEAREFGVRAGMPLRAAARRCPPDSGVTFL
PSDPAAYDAASDQVMGLLRDLGHPVEVWGWDEAYLAVTATDPIEVAEQIRGVISSETGLTCSVGISDNKQRAKIATGFAK
PDGVFVLTDANWMALMADRPVDALWGVGPKTAKKLADLQITTVWQLAHSDAELLTATFGPRTGLWLLLLAKGGGDDHVSA
QPWVPRSRSHVVTFPRDLTDRAEMETAVTDLADQAVAEVLTAGRVVTRVAVTVRTATFYTRTKIRKLDAPSTDRDVIVAA
ALRVLDLFELDRPVRLLGVRLELVMPD
>Mature_346_residues
SPRWVLHVDLDQFLASVELRRRPELAGLPVIVGGNGDPNEPRKVVTCASYEAREFGVRAGMPLRAAARRCPPDSGVTFLP
SDPAAYDAASDQVMGLLRDLGHPVEVWGWDEAYLAVTATDPIEVAEQIRGVISSETGLTCSVGISDNKQRAKIATGFAKP
DGVFVLTDANWMALMADRPVDALWGVGPKTAKKLADLQITTVWQLAHSDAELLTATFGPRTGLWLLLLAKGGGDDHVSAQ
PWVPRSRSHVVTFPRDLTDRAEMETAVTDLADQAVAEVLTAGRVVTRVAVTVRTATFYTRTKIRKLDAPSTDRDVIVAAA
LRVLDLFELDRPVRLLGVRLELVMPD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=418, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI7706681, Length=419, Percent_Identity=26.2529832935561, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI7705344, Length=113, Percent_Identity=36.283185840708, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1786425, Length=355, Percent_Identity=30.7042253521127, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1787432, Length=342, Percent_Identity=28.9473684210526, Blast_Score=111, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17537959, Length=347, Percent_Identity=28.2420749279539, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19923006, Length=341, Percent_Identity=26.099706744868, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37706; Mature: 37574

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRWVLHVDLDQFLASVELRRRPELAGLPVIVGGNGDPNEPRKVVTCASYEAREFGVRA
CCCCEEEEECHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCEEEEECCCCHHHHCCCC
GMPLRAAARRCPPDSGVTFLPSDPAAYDAASDQVMGLLRDLGHPVEVWGWDEAYLAVTAT
CCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEEEEC
DPIEVAEQIRGVISSETGLTCSVGISDNKQRAKIATGFAKPDGVFVLTDANWMALMADRP
CHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHEEECCCCCCCEEEEECCCEEEEEECCC
VDALWGVGPKTAKKLADLQITTVWQLAHSDAELLTATFGPRTGLWLLLLAKGGGDDHVSA
HHHHHCCCHHHHHHHHCEEEEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCC
QPWVPRSRSHVVTFPRDLTDRAEMETAVTDLADQAVAEVLTAGRVVTRVAVTVRTATFYT
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHEEEE
RTKIRKLDAPSTDRDVIVAAALRVLDLFELDRPVRLLGVRLELVMPD
HHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECC
>Mature Secondary Structure 
SPRWVLHVDLDQFLASVELRRRPELAGLPVIVGGNGDPNEPRKVVTCASYEAREFGVRA
CCCEEEEECHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCEEEEECCCCHHHHCCCC
GMPLRAAARRCPPDSGVTFLPSDPAAYDAASDQVMGLLRDLGHPVEVWGWDEAYLAVTAT
CCCHHHHHHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCEEEEEEEC
DPIEVAEQIRGVISSETGLTCSVGISDNKQRAKIATGFAKPDGVFVLTDANWMALMADRP
CHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHEEECCCCCCCEEEEECCCEEEEEECCC
VDALWGVGPKTAKKLADLQITTVWQLAHSDAELLTATFGPRTGLWLLLLAKGGGDDHVSA
HHHHHCCCHHHHHHHHCEEEEEEEEECCCCCCEEEEECCCCCCEEEEEEECCCCCCCCCC
QPWVPRSRSHVVTFPRDLTDRAEMETAVTDLADQAVAEVLTAGRVVTRVAVTVRTATFYT
CCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHEEEE
RTKIRKLDAPSTDRDVIVAAALRVLDLFELDRPVRLLGVRLELVMPD
HHHHEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]