Click here to switch to the map view.

The map label for this gene is echA17

Identifier: 41409185

GI number: 41409185

Start: 3434645

End: 3435418

Strand: Reverse

Name: echA17

Synonym: MAP3087c

Alternate gene names: 41409185

Gene position: 3435418-3434645 (Counterclockwise)

Preceding gene: 41409186

Following gene: 41409184

Centisome position: 71.13

GC content: 74.68

Gene sequence:

>774_bases
GTGGCGGCATTGAACGAGTTCGTCAGCGTCGTGGTCAGCGACGGCTCCCGGGACGCCGGGCTGGCGATGTTGCTGGTGTC
GCGCCCGCCCACCAACGCGTTGAGCCGCCAGGTGTACCGCGAGGTGATCGCGGCGGCCGACGAGCTCGGGCGGCGCGACG
ACGTGGCCGCGGTGATCCTGTTCGGCGGCCACGAGATCTTCTCCGCCGGCGACGACATGCCCGAGCTGCGCACGCTGCGC
GGCGCCGAGGCCGAGACCGCGGCCCGGGTCCGCCGCGACGCCATCGACGCCGTGGCGGCCATCCCCAAGCCGACCGTGGC
CGCGATCACCGGCTACGCGTTGGGCGCCGGGCTCACCCTGGCGCTGGCCGCCGACTGGCGGATCAGCGGCGACAACGTCA
AATTCGGCGCGACCGAGATCCTGGCCGGCCTGGTGCCCGGCGGCGACGCGCTGGCCCGCCTGACCCGGGTGGCCGGCGCG
AGCAAGGCCAAGGAGCTGGTGTTCAGCGGCCGGTTCTTCGACGCCGAGGAGGCCCTGGCGCTGGGGCTGATCGACGAAAT
GGTGGCCCCCGACGACGTGTACGACGCCGCCGCGGCGTGGGCGCGCCGGTTCCTGGACGGCCCGCGACACGCGCTGGCCG
CCGCCAAGGCCGGTGTCGACGCCGTGTTCGAGCTGCCCCGCGCCGAGCGGCTTGCCGCCGAACAGCGGCGCTACGTGGAG
GTGTTCTCCGCTGGTCAGGGCGGCGACGCGGGGGCGGATCCGCACGGCGGTTAG

Upstream 100 bases:

>100_bases
CTCCGGTGCAGCCGCATGTGGAGATCCGGGGCGACAACTGGGTGTTCGAGTTCTTCGACTCCGACCGCTACCACCGGGCG
CGGGAGGCCGGCGGGCTGGG

Downstream 100 bases:

>100_bases
GCTTGCCCTTCATGACCAGATCGACCGACGCCGTTCCGACGCCGCACGCCACCGCCGAACAGGTGGAAGCCGCCCGGCAC
GACAGCAAGCTGGCCCAGGT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MAALNEFVSVVVSDGSRDAGLAMLLVSRPPTNALSRQVYREVIAAADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLR
GAEAETAARVRRDAIDAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGLVPGGDALARLTRVAGA
SKAKELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAEQRRYVE
VFSAGQGGDAGADPHGG

Sequences:

>Translated_257_residues
MAALNEFVSVVVSDGSRDAGLAMLLVSRPPTNALSRQVYREVIAAADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLR
GAEAETAARVRRDAIDAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGLVPGGDALARLTRVAGA
SKAKELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAEQRRYVE
VFSAGQGGDAGADPHGG
>Mature_256_residues
AALNEFVSVVVSDGSRDAGLAMLLVSRPPTNALSRQVYREVIAAADELGRRDDVAAVILFGGHEIFSAGDDMPELRTLRG
AEAETAARVRRDAIDAVAAIPKPTVAAITGYALGAGLTLALAADWRISGDNVKFGATEILAGLVPGGDALARLTRVAGAS
KAKELVFSGRFFDAEEALALGLIDEMVAPDDVYDAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAEQRRYVEV
FSAGQGGDAGADPHGG

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=239, Percent_Identity=27.6150627615063, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI68989263, Length=215, Percent_Identity=32.093023255814, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI4502327, Length=216, Percent_Identity=35.1851851851852, Blast_Score=88, Evalue=6e-18,
Organism=Homo sapiens, GI157694516, Length=238, Percent_Identity=23.9495798319328, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI213417737, Length=238, Percent_Identity=23.9495798319328, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI20127408, Length=178, Percent_Identity=28.6516853932584, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI70995211, Length=179, Percent_Identity=30.7262569832402, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI45643119, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI260275230, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI260274832, Length=217, Percent_Identity=27.1889400921659, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI157694520, Length=203, Percent_Identity=25.1231527093596, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788597, Length=207, Percent_Identity=30.4347826086957, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787659, Length=232, Percent_Identity=31.8965517241379, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788682, Length=176, Percent_Identity=32.9545454545455, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI221142681, Length=236, Percent_Identity=29.6610169491525, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790281, Length=162, Percent_Identity=29.0123456790123, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082183, Length=187, Percent_Identity=26.2032085561497, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=230, Percent_Identity=31.304347826087, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17554946, Length=225, Percent_Identity=29.7777777777778, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25145438, Length=230, Percent_Identity=26.9565217391304, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17558304, Length=180, Percent_Identity=26.1111111111111, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=197, Percent_Identity=27.4111675126904, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=183, Percent_Identity=29.5081967213115, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17536985, Length=178, Percent_Identity=29.2134831460674, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=236, Percent_Identity=25.4237288135593, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129971, Length=239, Percent_Identity=30.5439330543933, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24653477, Length=239, Percent_Identity=30.5439330543933, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24653139, Length=240, Percent_Identity=30, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19920382, Length=173, Percent_Identity=31.7919075144509, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24583165, Length=186, Percent_Identity=28.494623655914, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921018, Length=205, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26738; Mature: 26607

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALNEFVSVVVSDGSRDAGLAMLLVSRPPTNALSRQVYREVIAAADELGRRDDVAAVIL
CCHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
FGGHEIFSAGDDMPELRTLRGAEAETAARVRRDAIDAVAAIPKPTVAAITGYALGAGLTL
ECCCHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEE
ALAADWRISGDNVKFGATEILAGLVPGGDALARLTRVAGASKAKELVFSGRFFDAEEALA
EEEECEEECCCCEEECHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHH
LGLIDEMVAPDDVYDAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAEQRRYVE
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHH
VFSAGQGGDAGADPHGG
HHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
AALNEFVSVVVSDGSRDAGLAMLLVSRPPTNALSRQVYREVIAAADELGRRDDVAAVIL
CHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
FGGHEIFSAGDDMPELRTLRGAEAETAARVRRDAIDAVAAIPKPTVAAITGYALGAGLTL
ECCCHHCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEEE
ALAADWRISGDNVKFGATEILAGLVPGGDALARLTRVAGASKAKELVFSGRFFDAEEALA
EEEECEEECCCCEEECHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHH
LGLIDEMVAPDDVYDAAAAWARRFLDGPRHALAAAKAGVDAVFELPRAERLAAEQRRYVE
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHH
VFSAGQGGDAGADPHGG
HHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA