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The map label for this gene is lipN

Identifier: 41409104

GI number: 41409104

Start: 3342617

End: 3343738

Strand: Reverse

Name: lipN

Synonym: MAP3006c

Alternate gene names: 41409104

Gene position: 3343738-3342617 (Counterclockwise)

Preceding gene: 41409106

Following gene: 41409103

Centisome position: 69.23

GC content: 73.62

Gene sequence:

>1122_bases
ATGACCAAGCCGCTGACCGACACCGCACCCGTCGACCCCGGCGCGCAGCGCGGGTCGATGCCGCTGACCAACCGCATCCA
GGGCGCCGTCACCAGCGTCGGGGTCAAGGTCATCCCGTGGATCCCGACCGCCGTGCGCCGCGGCCTGGTGCGCGGCCGCT
CGGTCATCATCGACGGCAACACGCTCGACCCGACCCTGCAGCTGATGCTGTCCGGTCTGCGCGCCGTCGGCATCGACGGC
CTGGTGGTCGACGACGACCCCGAGCTGTCCCGCGCCCAGATGCACGAGTCCACGGTGGGGTTCCCCGGCCCGCAGATCCA
CGTCGACGTCGCCGAACTGGCGCTGCCCGGCCCGGCCGGCGACATCCCGGCGCGGCACTATCGGCCCGCCGGCGGCGAGA
CCCAGGCCCCGCTGCTGGTCTTCTACCACGGCGGCGGCTGGTCGATCGGCGACCTGGACACCCACGACTCGCTGTGCCGG
CTGACCTGCCGCGACGCCGGCATCCACGTGCTGTCGATCGACTACCGGCTGGCGCCCGAGCATCCCGCGCCGGCCGCCAT
CGACGACGCGTACGCCGCCTTCACCTGGGCGCATGAGCATGCCGGCGAGCTGGGCGCGATCCCCGGGCGGGTGGCGGTCG
GCGGCGACAGCGCCGGCGGCAACCTGGCCGCCGTCGTCAGCCAGCTGGCCCGCGACGCGGGCGGCCCGGCACCGGTGCTG
CAGTGGCTGATCTACCCGCGCACCGACTTCACCGCCCGGACCCGGTCGCTGAGCCTGTTCTCCCGCGGCTTCCTGCTGAC
CAAGCGCGACATCGACTGGTTCGAATCGCAGTACCTGCGGAACTCGCGGCTGGACCGGACGGACCCGCGGGTATCGCCGG
CGCTGGCCGAATCGCTGGCCGGCCTGGCCCCGGCGCTGATCGCGGTGGCCGGCTTCGACCCGCTACGCGACGAGGGCCAG
AGCTACGCCGAGGCGCTGCGCGCCGCCGGCACCCCGGTGGACCTGCGGTACCTGGGTTCGCTGACGCACGGCTTCGCCAA
CCTGTTCCAGCTCGGCGGCGACAGCATGGTGGCCACCAGCGAGTTGATCTCGGCGCTGCGCGCGCACCTGAGCCGGGTCT
GA

Upstream 100 bases:

>100_bases
CACCACGTACAGTTAGCCTCCGTGACGACGGCGACGACGGGGCAGTGAACAACCGTTCGTCGTCGGGCGGTCCCACGTTC
GTGCGAGGGGGAGTAGCTCC

Downstream 100 bases:

>100_bases
TCCATGCGACGGGCGGCGCCGGTAATCTAGAGGCGCCTTGTCCGATCGCATTGTCGGCAGACCGACAACTCGAGTGACGA
AAGATCAGGGAACCCGTGGC

Product: LipN

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTKPLTDTAPVDPGAQRGSMPLTNRIQGAVTSVGVKVIPWIPTAVRRGLVRGRSVIIDGNTLDPTLQLMLSGLRAVGIDG
LVVDDDPELSRAQMHESTVGFPGPQIHVDVAELALPGPAGDIPARHYRPAGGETQAPLLVFYHGGGWSIGDLDTHDSLCR
LTCRDAGIHVLSIDYRLAPEHPAPAAIDDAYAAFTWAHEHAGELGAIPGRVAVGGDSAGGNLAAVVSQLARDAGGPAPVL
QWLIYPRTDFTARTRSLSLFSRGFLLTKRDIDWFESQYLRNSRLDRTDPRVSPALAESLAGLAPALIAVAGFDPLRDEGQ
SYAEALRAAGTPVDLRYLGSLTHGFANLFQLGGDSMVATSELISALRAHLSRV

Sequences:

>Translated_373_residues
MTKPLTDTAPVDPGAQRGSMPLTNRIQGAVTSVGVKVIPWIPTAVRRGLVRGRSVIIDGNTLDPTLQLMLSGLRAVGIDG
LVVDDDPELSRAQMHESTVGFPGPQIHVDVAELALPGPAGDIPARHYRPAGGETQAPLLVFYHGGGWSIGDLDTHDSLCR
LTCRDAGIHVLSIDYRLAPEHPAPAAIDDAYAAFTWAHEHAGELGAIPGRVAVGGDSAGGNLAAVVSQLARDAGGPAPVL
QWLIYPRTDFTARTRSLSLFSRGFLLTKRDIDWFESQYLRNSRLDRTDPRVSPALAESLAGLAPALIAVAGFDPLRDEGQ
SYAEALRAAGTPVDLRYLGSLTHGFANLFQLGGDSMVATSELISALRAHLSRV
>Mature_372_residues
TKPLTDTAPVDPGAQRGSMPLTNRIQGAVTSVGVKVIPWIPTAVRRGLVRGRSVIIDGNTLDPTLQLMLSGLRAVGIDGL
VVDDDPELSRAQMHESTVGFPGPQIHVDVAELALPGPAGDIPARHYRPAGGETQAPLLVFYHGGGWSIGDLDTHDSLCRL
TCRDAGIHVLSIDYRLAPEHPAPAAIDDAYAAFTWAHEHAGELGAIPGRVAVGGDSAGGNLAAVVSQLARDAGGPAPVLQ
WLIYPRTDFTARTRSLSLFSRGFLLTKRDIDWFESQYLRNSRLDRTDPRVSPALAESLAGLAPALIAVAGFDPLRDEGQS
YAEALRAAGTPVDLRYLGSLTHGFANLFQLGGDSMVATSELISALRAHLSRV

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI157041239, Length=309, Percent_Identity=25.5663430420712, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI206597554, Length=285, Percent_Identity=29.1228070175439, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI68299767, Length=288, Percent_Identity=28.4722222222222, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI21328446, Length=121, Percent_Identity=35.5371900826446, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI68051721, Length=271, Percent_Identity=26.9372693726937, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI61966717, Length=313, Percent_Identity=24.2811501597444, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786682, Length=237, Percent_Identity=32.9113924050633, Blast_Score=102, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17567059, Length=265, Percent_Identity=31.3207547169811, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17540028, Length=135, Percent_Identity=37.7777777777778, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72001146, Length=128, Percent_Identity=37.5, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71996133, Length=132, Percent_Identity=37.1212121212121, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 39573; Mature: 39442

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPLTDTAPVDPGAQRGSMPLTNRIQGAVTSVGVKVIPWIPTAVRRGLVRGRSVIIDGN
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCEEEEECC
TLDPTLQLMLSGLRAVGIDGLVVDDDPELSRAQMHESTVGFPGPQIHVDVAELALPGPAG
CCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCC
DIPARHYRPAGGETQAPLLVFYHGGGWSIGDLDTHDSLCRLTCRDAGIHVLSIDYRLAPE
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHEEEECCCCEEEEEEEEEECCC
HPAPAAIDDAYAAFTWAHEHAGELGAIPGRVAVGGDSAGGNLAAVVSQLARDAGGPAPVL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHH
QWLIYPRTDFTARTRSLSLFSRGFLLTKRDIDWFESQYLRNSRLDRTDPRVSPALAESLA
HHHHCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
GLAPALIAVAGFDPLRDEGQSYAEALRAAGTPVDLRYLGSLTHGFANLFQLGGDSMVATS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
ELISALRAHLSRV
HHHHHHHHHHHCC
>Mature Secondary Structure 
TKPLTDTAPVDPGAQRGSMPLTNRIQGAVTSVGVKVIPWIPTAVRRGLVRGRSVIIDGN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCEEEEECC
TLDPTLQLMLSGLRAVGIDGLVVDDDPELSRAQMHESTVGFPGPQIHVDVAELALPGPAG
CCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHCCCCCCCEEEEEHHHHCCCCCCC
DIPARHYRPAGGETQAPLLVFYHGGGWSIGDLDTHDSLCRLTCRDAGIHVLSIDYRLAPE
CCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHEEEECCCCEEEEEEEEEECCC
HPAPAAIDDAYAAFTWAHEHAGELGAIPGRVAVGGDSAGGNLAAVVSQLARDAGGPAPVL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCHHHH
QWLIYPRTDFTARTRSLSLFSRGFLLTKRDIDWFESQYLRNSRLDRTDPRVSPALAESLA
HHHHCCCCCCHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
GLAPALIAVAGFDPLRDEGQSYAEALRAAGTPVDLRYLGSLTHGFANLFQLGGDSMVATS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHH
ELISALRAHLSRV
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]