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The map label for this gene is lldD [C]

Identifier: 41409057

GI number: 41409057

Start: 3292215

End: 3293375

Strand: Reverse

Name: lldD [C]

Synonym: MAP2959c

Alternate gene names: 41409057

Gene position: 3293375-3292215 (Counterclockwise)

Preceding gene: 41409058

Following gene: 41409056

Centisome position: 68.19

GC content: 71.92

Gene sequence:

>1161_bases
ATGGCGTTCGGCGACTACCAGAACGAGATCTACTTCCGCGGCCTGGGCGGGGTGGCGCCGTCGCTGCCGATGGCCTTCGC
CGAGCTGGAGTCCCGCGCCGAGCGGGCCATGTCGCCGTCGGTGTGGTCCTACGTCACCGGCGGCGCCGGCGACGAACGCA
CCCAGCGGGCCAACCGGGAGGCGTTCGACCGCTGGGGCCTGATCCCGCGCATGTTCGTCGGCGCCGCCGAACGCGACCTG
TCGGTGCAGATGTTCGGCCTGACCCTGCCGTCGCCGGTGTTCATGGCGCCGATCGGCGTCATCGGCATCTGCGCCCAGGA
CGGCCACGGCGACCTCGCCACCGCGCGGGCGGCCGCGGCCACCGGCGTCCCCATGGTCGTTTCCACCCTGACCGCCGACC
CGATGGAAGACGTCGCCGCGCAGTTCGGCGACACCCCCGGCTTCTTTCAGCTCTACACGCCGAAGGACCGGGAGCTGGCC
GCCAGCCTCGTGCACCGGGCCGAGGCCGCCGGCTTCAAGGGCATCATCGTCACCCTGGACACCTGGATCCCCGGCTGGCG
ACCGCGCGACCTGTCCACCGCCAACTTTCCCCAGCTGCGGGGGATGTGCCTGAGCAACTACACCAGCGATCCGGTGTTCC
GCGCCGCCCTGGCGCGCCCGCCCGAGGAGGACCCGCAGGGCACCGTGCTGCAGTGGATATCGACCTTCGGAAACCCGCTG
ACCTGGGACGACCTGCCCTGGCTTCGGTCGCTGACCGATCTGCCGCTGATCATCAAGGGCATCTGCCACCCCGACGACGC
CCGCCGCGCCCGCGACGGCGGCGTCGACGGCATCTACTGCTCCACCCACGGCGGACGCCAGGCCAACGGCGGGCTGCCGG
CGCTGGACTGCCTGCCCGGGGTGATCGAGGCGGCCGACGGTCTGCCGGTGCTGTTCGACTCCGGGATCCGCAGCGGCGCC
GACGTCGTCAAGGCGCTCGCGCTGGGCGCCACCGCGGTCGGCATCGGCCGCCCGTATGCGTATGGCCTGGCGCTCGGCGG
CGTCGACGGCATCGTGCACGCGCTGCGCTCGATCCTGGCCGAGGCCGACCTCATCATGGCCGTCGACGGATATCCGACGC
GCAAAGATCTCACCCCGGACACGCTTCGGCGCGTCGTCTGA

Upstream 100 bases:

>100_bases
CGCCGCGGCCGCACCGAAGAGACGTTCCGGCAGTGGAAGAAGGAACTGGCCCAGGCGGAGTCGGCGCAAGCCTGACGGCC
CGACTGGCATCCTCTATCTC

Downstream 100 bases:

>100_bases
GTCCGGCCGCCCGGTTTCTGCCAGCGTGGGGGAGTGCCGGACAGCGAACCGATCCTCGAGGAGTTCGACGAGTACCTGGC
GCTGCAGTGCGGGCGTTCGG

Product: hypothetical protein

Products: NA

Alternate protein names: Lactate oxidase [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MAFGDYQNEIYFRGLGGVAPSLPMAFAELESRAERAMSPSVWSYVTGGAGDERTQRANREAFDRWGLIPRMFVGAAERDL
SVQMFGLTLPSPVFMAPIGVIGICAQDGHGDLATARAAAATGVPMVVSTLTADPMEDVAAQFGDTPGFFQLYTPKDRELA
ASLVHRAEAAGFKGIIVTLDTWIPGWRPRDLSTANFPQLRGMCLSNYTSDPVFRAALARPPEEDPQGTVLQWISTFGNPL
TWDDLPWLRSLTDLPLIIKGICHPDDARRARDGGVDGIYCSTHGGRQANGGLPALDCLPGVIEAADGLPVLFDSGIRSGA
DVVKALALGATAVGIGRPYAYGLALGGVDGIVHALRSILAEADLIMAVDGYPTRKDLTPDTLRRVV

Sequences:

>Translated_386_residues
MAFGDYQNEIYFRGLGGVAPSLPMAFAELESRAERAMSPSVWSYVTGGAGDERTQRANREAFDRWGLIPRMFVGAAERDL
SVQMFGLTLPSPVFMAPIGVIGICAQDGHGDLATARAAAATGVPMVVSTLTADPMEDVAAQFGDTPGFFQLYTPKDRELA
ASLVHRAEAAGFKGIIVTLDTWIPGWRPRDLSTANFPQLRGMCLSNYTSDPVFRAALARPPEEDPQGTVLQWISTFGNPL
TWDDLPWLRSLTDLPLIIKGICHPDDARRARDGGVDGIYCSTHGGRQANGGLPALDCLPGVIEAADGLPVLFDSGIRSGA
DVVKALALGATAVGIGRPYAYGLALGGVDGIVHALRSILAEADLIMAVDGYPTRKDLTPDTLRRVV
>Mature_385_residues
AFGDYQNEIYFRGLGGVAPSLPMAFAELESRAERAMSPSVWSYVTGGAGDERTQRANREAFDRWGLIPRMFVGAAERDLS
VQMFGLTLPSPVFMAPIGVIGICAQDGHGDLATARAAAATGVPMVVSTLTADPMEDVAAQFGDTPGFFQLYTPKDRELAA
SLVHRAEAAGFKGIIVTLDTWIPGWRPRDLSTANFPQLRGMCLSNYTSDPVFRAALARPPEEDPQGTVLQWISTFGNPLT
WDDLPWLRSLTDLPLIIKGICHPDDARRARDGGVDGIYCSTHGGRQANGGLPALDCLPGVIEAADGLPVLFDSGIRSGAD
VVKALALGATAVGIGRPYAYGLALGGVDGIVHALRSILAEADLIMAVDGYPTRKDLTPDTLRRVV

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI11068137, Length=368, Percent_Identity=36.6847826086957, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI54234014, Length=349, Percent_Identity=34.0974212034384, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI7705393, Length=349, Percent_Identity=34.0974212034384, Blast_Score=189, Evalue=3e-48,
Organism=Escherichia coli, GI1790033, Length=384, Percent_Identity=34.6354166666667, Blast_Score=193, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI193208036, Length=358, Percent_Identity=34.0782122905028, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI32566217, Length=295, Percent_Identity=32.2033898305085, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323587, Length=369, Percent_Identity=30.6233062330623, Blast_Score=176, Evalue=4e-45,
Organism=Drosophila melanogaster, GI78707188, Length=356, Percent_Identity=34.2696629213483, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI281363140, Length=356, Percent_Identity=34.2696629213483, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI78707190, Length=356, Percent_Identity=34.2696629213483, Blast_Score=186, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.13.12.4 [H]

Molecular weight: Translated: 41155; Mature: 41024

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFGDYQNEIYFRGLGGVAPSLPMAFAELESRAERAMSPSVWSYVTGGAGDERTQRANRE
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHH
AFDRWGLIPRMFVGAAERDLSVQMFGLTLPSPVFMAPIGVIGICAQDGHGDLATARAAAA
HHHHHCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHH
TGVPMVVSTLTADPMEDVAAQFGDTPGFFQLYTPKDRELAASLVHRAEAAGFKGIIVTLD
CCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEE
TWIPGWRPRDLSTANFPQLRGMCLSNYTSDPVFRAALARPPEEDPQGTVLQWISTFGNPL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
TWDDLPWLRSLTDLPLIIKGICHPDDARRARDGGVDGIYCSTHGGRQANGGLPALDCLPG
CCCCCHHHHHHCCCCHHHHHCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHH
VIEAADGLPVLFDSGIRSGADVVKALALGATAVGIGRPYAYGLALGGVDGIVHALRSILA
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
EADLIMAVDGYPTRKDLTPDTLRRVV
CCCEEEEECCCCCCCCCCHHHHHHCC
>Mature Secondary Structure 
AFGDYQNEIYFRGLGGVAPSLPMAFAELESRAERAMSPSVWSYVTGGAGDERTQRANRE
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHH
AFDRWGLIPRMFVGAAERDLSVQMFGLTLPSPVFMAPIGVIGICAQDGHGDLATARAAAA
HHHHHCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHCCCEEEEEECCCCCCHHHHHHHHH
TGVPMVVSTLTADPMEDVAAQFGDTPGFFQLYTPKDRELAASLVHRAEAAGFKGIIVTLD
CCCHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCEEEEEEE
TWIPGWRPRDLSTANFPQLRGMCLSNYTSDPVFRAALARPPEEDPQGTVLQWISTFGNPL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
TWDDLPWLRSLTDLPLIIKGICHPDDARRARDGGVDGIYCSTHGGRQANGGLPALDCLPG
CCCCCHHHHHHCCCCHHHHHCCCCCHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHH
VIEAADGLPVLFDSGIRSGADVVKALALGATAVGIGRPYAYGLALGGVDGIVHALRSILA
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHH
EADLIMAVDGYPTRKDLTPDTLRRVV
CCCEEEEECCCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2324094; 3571231 [H]