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The map label for this gene is mpt53

Identifier: 41409040

GI number: 41409040

Start: 3277656

End: 3278174

Strand: Reverse

Name: mpt53

Synonym: MAP2942c

Alternate gene names: 41409040

Gene position: 3278174-3277656 (Counterclockwise)

Preceding gene: 41409041

Following gene: 41409039

Centisome position: 67.87

GC content: 70.13

Gene sequence:

>519_bases
GTGCGTCTTCAGGGCATGTCCCGTTTGTCATTTGTCTGCAGGCTTTTGGCCGCAACCGCTTTCGCCGTCGCCCTGCTACT
CGGGCTGGGCGACGTGCCGCGCGCGGCGGCCACCGACGACCGCCTGCAATTCACCGCGACCACGCTCAGCGGCGCGCCGT
TCAACGGCGCCAGTCTGCAGGGCAAGCCCGCCGTGCTGTGGTTCTGGACGCCGTGGTGCCCGTACTGCAACGCCGAGGCC
CCGGGCGTGAGCCGGGTGGCCGCCGCCAACCCGGGCGTCACCTTCGTCGGCGTCGCCGCCCACTCCGAAGTCGGCGCCAT
GGCCAACTTCGTCTCCAAGTACAACCTGAACTTCACCACGCTCAACGACGCCGACGGCGCGATCTGGGCCCGCTACGGCG
TGCCCTGGCAGCCCGCGTACGTGTTCTACCGGGCGGACGGCAGCTCCACCTTCGTCAACAACCCCACCTCGGCGATGCCC
CAGGACGAACTGGCCGCCCGGGTGGCGGCGCTGCGCTGA

Upstream 100 bases:

>100_bases
TCGGGCCTGGGCCTGCGGACAGCTCGCCGCCGAAGGCGGGTAGCTGGCCTTCGAGAAGGGATAGCAGGCGGGGCCGGGCG
GTGAACCCGGGAGGCGCGCG

Downstream 100 bases:

>100_bases
CGTGGACCGCGGTCTGGTCGGGCTGGCGGTTGCCGCCGGCATGGTGGCGGCGCTGAACCCGTGCGGGTTCGCGATGCTGC
CCGCCTATCTGCTGCTGGTG

Product: Mpt53

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRLQGMSRLSFVCRLLAATAFAVALLLGLGDVPRAAATDDRLQFTATTLSGAPFNGASLQGKPAVLWFWTPWCPYCNAEA
PGVSRVAAANPGVTFVGVAAHSEVGAMANFVSKYNLNFTTLNDADGAIWARYGVPWQPAYVFYRADGSSTFVNNPTSAMP
QDELAARVAALR

Sequences:

>Translated_172_residues
MRLQGMSRLSFVCRLLAATAFAVALLLGLGDVPRAAATDDRLQFTATTLSGAPFNGASLQGKPAVLWFWTPWCPYCNAEA
PGVSRVAAANPGVTFVGVAAHSEVGAMANFVSKYNLNFTTLNDADGAIWARYGVPWQPAYVFYRADGSSTFVNNPTSAMP
QDELAARVAALR
>Mature_172_residues
MRLQGMSRLSFVCRLLAATAFAVALLLGLGDVPRAAATDDRLQFTATTLSGAPFNGASLQGKPAVLWFWTPWCPYCNAEA
PGVSRVAAANPGVTFVGVAAHSEVGAMANFVSKYNLNFTTLNDADGAIWARYGVPWQPAYVFYRADGSSTFVNNPTSAMP
QDELAARVAALR

Specific function: Disulfide oxidoreductase that catalyzes the oxidation of reduced, unfolded secreted proteins to form disulfide bonds. Despite a weak homology to thioredoxin this cannot serve as a substrate for thioredoxin reductase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 18294; Mature: 18294

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLQGMSRLSFVCRLLAATAFAVALLLGLGDVPRAAATDDRLQFTATTLSGAPFNGASLQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
GKPAVLWFWTPWCPYCNAEAPGVSRVAAANPGVTFVGVAAHSEVGAMANFVSKYNLNFTT
CCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCEEE
LNDADGAIWARYGVPWQPAYVFYRADGSSTFVNNPTSAMPQDELAARVAALR
ECCCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRLQGMSRLSFVCRLLAATAFAVALLLGLGDVPRAAATDDRLQFTATTLSGAPFNGASLQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCC
GKPAVLWFWTPWCPYCNAEAPGVSRVAAANPGVTFVGVAAHSEVGAMANFVSKYNLNFTT
CCCEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEEEEECCCHHHHHHHHHHHHCCCEEE
LNDADGAIWARYGVPWQPAYVFYRADGSSTFVNNPTSAMPQDELAARVAALR
ECCCCCEEEEECCCCCCCEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]