Click here to switch to the map view.

The map label for this gene is fadD13

Identifier: 41408972

GI number: 41408972

Start: 3203540

End: 3205072

Strand: Reverse

Name: fadD13

Synonym: MAP2874c

Alternate gene names: 41408972

Gene position: 3205072-3203540 (Counterclockwise)

Preceding gene: 41408974

Following gene: 41408971

Centisome position: 66.36

GC content: 70.25

Gene sequence:

>1533_bases
ATGCCGCCAGTGATCGAAATCGCGCGGGAGCACAACCCGTTCCCGACCACCGGCGTGTCCCGCGGCCGCGACGGCATTCC
GCGCTACGACGAGCTGCCCGCCACGCTGGTGGACATGCTCGCCGACCAGGTCGACGCCCGCCCGGACAGCGAGGCCGTGG
TCGAGCTCGGCGGTGGCCGGCTGACGTACCGGCAGCTGTGGGACCGGGCGGCGCGGGTGGCCGGCGGGCTGCGCGCCGAC
GGTCTGCGGCGGGGGGACCGCGTCGCGGTGCGCTATCCCGCCGGGATCGACTGGGTGCTGGCCTTCTGGGGCACGGTGCT
GGCCGGCGGCGTTGCGGTGGCGGTCAATACGCGCTCCGCGCAACCGGAGGTCGATTTCGTGCTGTCCGACTCCGGTGCAC
GGCTACAGCTGGCGCCGGGTGACCCGCTGCCGGACGGAAAACCCTACGTCACCGAGCAACTCGGCGCGGCCGACACCGCC
GCCCTGTTCTACACGTCGGGCACCACCGGCTACCCCAAGGGCGTGCCGACCACACACGAGGCATTCCTGACCAACACCGA
GAACGCGATCCGCTGCTTGCAGCAGCCGCGGGACCTGGGCGAGGACATGCGCACGCTGATCTCGGTGCCGCTGTTCCATG
TGACCGGTTGCAACTCACAGCTTTTGGCCGCGGCCCGGCTCGGGGGAGCGTCGGTGATCCTGCCCGCGCTCGACCTGGAT
GCGCTGCTCAACGCGGTGGTCGCCGAACGTGTCTCGGTGATGGTCACCGTCCCGGCGATCTATGCATTGTTGTTGCGCCA
CAAGGATTTTGCCGGAACCGACGTATCCCGCGTGCGCTGGGTCGGTTACGGCGGGGCGCCCATCGCGCCGTCGCTGGTGC
GCACGGTGAAAGACGCTTTCCCGCACGCCACGGTGTTCAACGGCTATGGCATGACCGAGACGGCGTCGCTGATGACGGTG
CTGCCCGACCGCGAAGCGGTCGAGCATGCCGATTCGGTCGGGTATGCGGTCCCGTCGGTGGACCTGGGGCTGATCCCGTT
CGGCGACAACGAACCCGGCGTCGGGGAGTTGGTCACCCGCGGCGCCAACGTGACCGCCGGCTACTGGAATCGGCCGCAGG
CCACCGCGAGCACCTTCGCCGGGGGCTGGCTGCACACCGGCGACGTGGTGCGCGTCGACGACGCCGGCCGGGTGCACATC
ATCGACCGGCTCAAGGACATCATCAACCGCGGCGGCGAGAACGTCTCCAGCGTCGAGGTCGAGGCGGTGCTGCTGGGTGC
GCCCGGCGTCGCGGATGCGTGCGTGCTGGGGGTGCCCGACGACGTGATGGGCGAGAAAGTGGGGGCGGTGCTGTTCGGCG
ACGACGACATCGACGTGCCGGCGGTGCTCGAGCACTGCCGTGGCCGGCTGGCCGACTTCAAGGTGCCGCAGTACGTTACG
GTCGTCGACGGCCCACTGCCGCGCAATGCCGGCGGCAAGCTGCTCAAGGCCAGACTGCGCGACCAGGTGCACTGGGGTGA
CCCGCTGCGATGA

Upstream 100 bases:

>100_bases
CAGTGAAAAACGCCTCGGGCATGATGGCGGGATCCTCGATCGTCACCGCTATCACGATAGGGCAGCAGGCAGGATAGGCA
GCAGGATAGGTAGGACCGGC

Downstream 100 bases:

>100_bases
CCGCGAGCCTGCTGGTCGCCAACCGCGGCGAGATCGCACTTCGAATCATCCGCACCGCAACAGAACTGGGTATGCGAACC
GTCGCCGTGTACGCCGCGGA

Product: FadD13

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 510; Mature: 509

Protein sequence:

>510_residues
MPPVIEIAREHNPFPTTGVSRGRDGIPRYDELPATLVDMLADQVDARPDSEAVVELGGGRLTYRQLWDRAARVAGGLRAD
GLRRGDRVAVRYPAGIDWVLAFWGTVLAGGVAVAVNTRSAQPEVDFVLSDSGARLQLAPGDPLPDGKPYVTEQLGAADTA
ALFYTSGTTGYPKGVPTTHEAFLTNTENAIRCLQQPRDLGEDMRTLISVPLFHVTGCNSQLLAAARLGGASVILPALDLD
ALLNAVVAERVSVMVTVPAIYALLLRHKDFAGTDVSRVRWVGYGGAPIAPSLVRTVKDAFPHATVFNGYGMTETASLMTV
LPDREAVEHADSVGYAVPSVDLGLIPFGDNEPGVGELVTRGANVTAGYWNRPQATASTFAGGWLHTGDVVRVDDAGRVHI
IDRLKDIINRGGENVSSVEVEAVLLGAPGVADACVLGVPDDVMGEKVGAVLFGDDDIDVPAVLEHCRGRLADFKVPQYVT
VVDGPLPRNAGGKLLKARLRDQVHWGDPLR

Sequences:

>Translated_510_residues
MPPVIEIAREHNPFPTTGVSRGRDGIPRYDELPATLVDMLADQVDARPDSEAVVELGGGRLTYRQLWDRAARVAGGLRAD
GLRRGDRVAVRYPAGIDWVLAFWGTVLAGGVAVAVNTRSAQPEVDFVLSDSGARLQLAPGDPLPDGKPYVTEQLGAADTA
ALFYTSGTTGYPKGVPTTHEAFLTNTENAIRCLQQPRDLGEDMRTLISVPLFHVTGCNSQLLAAARLGGASVILPALDLD
ALLNAVVAERVSVMVTVPAIYALLLRHKDFAGTDVSRVRWVGYGGAPIAPSLVRTVKDAFPHATVFNGYGMTETASLMTV
LPDREAVEHADSVGYAVPSVDLGLIPFGDNEPGVGELVTRGANVTAGYWNRPQATASTFAGGWLHTGDVVRVDDAGRVHI
IDRLKDIINRGGENVSSVEVEAVLLGAPGVADACVLGVPDDVMGEKVGAVLFGDDDIDVPAVLEHCRGRLADFKVPQYVT
VVDGPLPRNAGGKLLKARLRDQVHWGDPLR
>Mature_509_residues
PPVIEIAREHNPFPTTGVSRGRDGIPRYDELPATLVDMLADQVDARPDSEAVVELGGGRLTYRQLWDRAARVAGGLRADG
LRRGDRVAVRYPAGIDWVLAFWGTVLAGGVAVAVNTRSAQPEVDFVLSDSGARLQLAPGDPLPDGKPYVTEQLGAADTAA
LFYTSGTTGYPKGVPTTHEAFLTNTENAIRCLQQPRDLGEDMRTLISVPLFHVTGCNSQLLAAARLGGASVILPALDLDA
LLNAVVAERVSVMVTVPAIYALLLRHKDFAGTDVSRVRWVGYGGAPIAPSLVRTVKDAFPHATVFNGYGMTETASLMTVL
PDREAVEHADSVGYAVPSVDLGLIPFGDNEPGVGELVTRGANVTAGYWNRPQATASTFAGGWLHTGDVVRVDDAGRVHII
DRLKDIINRGGENVSSVEVEAVLLGAPGVADACVLGVPDDVMGEKVGAVLFGDDDIDVPAVLEHCRGRLADFKVPQYVTV
VDGPLPRNAGGKLLKARLRDQVHWGDPLR

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=530, Percent_Identity=27.7358490566038, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI187761345, Length=519, Percent_Identity=29.6724470134875, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI187761343, Length=519, Percent_Identity=29.6724470134875, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI38505220, Length=560, Percent_Identity=24.4642857142857, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI42544132, Length=549, Percent_Identity=23.4972677595628, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI157311624, Length=542, Percent_Identity=24.5387453874539, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI157311622, Length=542, Percent_Identity=24.5387453874539, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI58082049, Length=541, Percent_Identity=24.3992606284658, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI115511026, Length=506, Percent_Identity=22.9249011857708, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI122937307, Length=571, Percent_Identity=21.5411558669002, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI28416953, Length=385, Percent_Identity=24.9350649350649, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI40807491, Length=336, Percent_Identity=27.6785714285714, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI13325057, Length=367, Percent_Identity=24.5231607629428, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI57165412, Length=372, Percent_Identity=27.4193548387097, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI57165410, Length=372, Percent_Identity=27.1505376344086, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1788107, Length=535, Percent_Identity=30.6542056074766, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI145693145, Length=521, Percent_Identity=29.5585412667946, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI221142682, Length=508, Percent_Identity=27.3622047244095, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786810, Length=525, Percent_Identity=28.952380952381, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1789201, Length=311, Percent_Identity=28.2958199356913, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788595, Length=466, Percent_Identity=25.3218884120172, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1790505, Length=378, Percent_Identity=27.5132275132275, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786801, Length=457, Percent_Identity=26.0393873085339, Blast_Score=76, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=569, Percent_Identity=27.5922671353251, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17559526, Length=496, Percent_Identity=28.0241935483871, Blast_Score=158, Evalue=5e-39,
Organism=Caenorhabditis elegans, GI71994690, Length=362, Percent_Identity=29.8342541436464, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71994703, Length=362, Percent_Identity=29.8342541436464, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71994694, Length=362, Percent_Identity=29.8342541436464, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI17531443, Length=520, Percent_Identity=25.7692307692308, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI71996755, Length=499, Percent_Identity=25.6513026052104, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32563687, Length=499, Percent_Identity=25.6513026052104, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17558820, Length=505, Percent_Identity=27.3267326732673, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17538037, Length=361, Percent_Identity=29.0858725761773, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17557194, Length=357, Percent_Identity=28.8515406162465, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71985884, Length=359, Percent_Identity=27.2980501392758, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17560140, Length=376, Percent_Identity=24.7340425531915, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25147511, Length=359, Percent_Identity=26.7409470752089, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17510401, Length=356, Percent_Identity=26.123595505618, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17553312, Length=172, Percent_Identity=33.1395348837209, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319699, Length=353, Percent_Identity=31.1614730878187, Blast_Score=143, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6323182, Length=546, Percent_Identity=23.2600732600733, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319264, Length=549, Percent_Identity=22.9508196721311, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24581924, Length=353, Percent_Identity=32.8611898016997, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI18859661, Length=505, Percent_Identity=26.9306930693069, Blast_Score=158, Evalue=7e-39,
Organism=Drosophila melanogaster, GI21355181, Length=367, Percent_Identity=29.4277929155313, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19922652, Length=458, Percent_Identity=24.6724890829694, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI281365686, Length=334, Percent_Identity=26.6467065868263, Blast_Score=108, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21358303, Length=489, Percent_Identity=23.5173824130879, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24648260, Length=430, Percent_Identity=24.4186046511628, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21356441, Length=309, Percent_Identity=25.5663430420712, Blast_Score=102, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24653035, Length=380, Percent_Identity=24.4736842105263, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21356947, Length=361, Percent_Identity=25.207756232687, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24648257, Length=381, Percent_Identity=27.0341207349081, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI20130357, Length=376, Percent_Identity=23.6702127659574, Blast_Score=94, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24648255, Length=361, Percent_Identity=24.3767313019391, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24648253, Length=352, Percent_Identity=24.4318181818182, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI161076582, Length=387, Percent_Identity=23.5142118863049, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24656500, Length=366, Percent_Identity=24.8633879781421, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19921316, Length=178, Percent_Identity=33.7078651685393, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020459
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 54200; Mature: 54069

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVIEIAREHNPFPTTGVSRGRDGIPRYDELPATLVDMLADQVDARPDSEAVVELGGGR
CCCHHHHHHCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCEEEECCCE
LTYRQLWDRAARVAGGLRADGLRRGDRVAVRYPAGIDWVLAFWGTVLAGGVAVAVNTRSA
EHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCC
QPEVDFVLSDSGARLQLAPGDPLPDGKPYVTEQLGAADTAALFYTSGTTGYPKGVPTTHE
CCCEEEEECCCCCEEEECCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHH
AFLTNTENAIRCLQQPRDLGEDMRTLISVPLFHVTGCNSQLLAAARLGGASVILPALDLD
HHCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCEEEEECCCHH
ALLNAVVAERVSVMVTVPAIYALLLRHKDFAGTDVSRVRWVGYGGAPIAPSLVRTVKDAF
HHHHHHHHHHHHEEEEHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHC
PHATVFNGYGMTETASLMTVLPDREAVEHADSVGYAVPSVDLGLIPFGDNEPGVGELVTR
CCCEEECCCCCCHHHHHHEECCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHC
GANVTAGYWNRPQATASTFAGGWLHTGDVVRVDDAGRVHIIDRLKDIINRGGENVSSVEV
CCCEECCCCCCCCHHHHHHCCCCEECCCEEEECCCCCEEHHHHHHHHHHCCCCCCCEEEE
EAVLLGAPGVADACVLGVPDDVMGEKVGAVLFGDDDIDVPAVLEHCRGRLADFKVPQYVT
EEEEECCCCCCCEEEECCCHHHHHHHHCEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEE
VVDGPLPRNAGGKLLKARLRDQVHWGDPLR
EECCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PPVIEIAREHNPFPTTGVSRGRDGIPRYDELPATLVDMLADQVDARPDSEAVVELGGGR
CCHHHHHHCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCEEEECCCE
LTYRQLWDRAARVAGGLRADGLRRGDRVAVRYPAGIDWVLAFWGTVLAGGVAVAVNTRSA
EHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCC
QPEVDFVLSDSGARLQLAPGDPLPDGKPYVTEQLGAADTAALFYTSGTTGYPKGVPTTHE
CCCEEEEECCCCCEEEECCCCCCCCCCCHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHH
AFLTNTENAIRCLQQPRDLGEDMRTLISVPLFHVTGCNSQLLAAARLGGASVILPALDLD
HHCCCCHHHHHHHHCHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCEEEEECCCHH
ALLNAVVAERVSVMVTVPAIYALLLRHKDFAGTDVSRVRWVGYGGAPIAPSLVRTVKDAF
HHHHHHHHHHHHEEEEHHHHHHHHHHCCCCCCCCHHHEEEEECCCCCCHHHHHHHHHHHC
PHATVFNGYGMTETASLMTVLPDREAVEHADSVGYAVPSVDLGLIPFGDNEPGVGELVTR
CCCEEECCCCCCHHHHHHEECCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHC
GANVTAGYWNRPQATASTFAGGWLHTGDVVRVDDAGRVHIIDRLKDIINRGGENVSSVEV
CCCEECCCCCCCCHHHHHHCCCCEECCCEEEECCCCCEEHHHHHHHHHHCCCCCCCEEEE
EAVLLGAPGVADACVLGVPDDVMGEKVGAVLFGDDDIDVPAVLEHCRGRLADFKVPQYVT
EEEEECCCCCCCEEEECCCHHHHHHHHCEEEECCCCCCHHHHHHHHCCCCCCCCCCCEEE
VVDGPLPRNAGGKLLKARLRDQVHWGDPLR
EECCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]