Click here to switch to the map view.

The map label for this gene is fadE20_2

Identifier: 41408936

GI number: 41408936

Start: 3166711

End: 3167910

Strand: Reverse

Name: fadE20_2

Synonym: MAP2838c

Alternate gene names: 41408936

Gene position: 3167910-3166711 (Counterclockwise)

Preceding gene: 41408937

Following gene: 41408935

Centisome position: 65.59

GC content: 64.33

Gene sequence:

>1200_bases
ATGTTGGGCGGCAGCAATCCCAGTCGCCCGGAGGTCGTCCATGAGCAGCGCCATCAAATACCAGCGCACGCTTTTCGAGT
CAGAACACGAACTGTTCCGCGAGTCCTACCGGGCCTTCCTCGATCGTCACGTCGCGCCGTATCACGACGAATGGGAGAAG
GCGAAGATCGTCGACCGCGGGGTGTGGCTCGAGGCCGGCAAGCAGGGCTTCCTGGGCATGGCGGTGCCCGAGGAGTACGG
CGGCGGGGGCAACCCCGATTTCCGGTACAACACCATCATCACCGAGGAGACCACCCGCGGCCGCTACAGCGGGATCGGCT
TCGGCCTGCACAACGACATCGTCGCGCCCTACCTGCTGGCCCTGGCCACCGAGGAGCAGAAGCAGCGCTGGCTGCCGAAA
TTCTGCACAGGAGAACTGATTACGGCGATCGCGATGACCGAGCCGGGCACCGGCAGCGACCTGCAGGGCATCAAGACCCG
GGCGGTCAAGCAGGGCGACCACTACGTGCTCAACGGGTCAAAGACGTTCATCACCAACGGATCAACTCCGATCTGGTGAT
CGTGGTGGCCCAGACCGATCCGGACAAGGGGGCGCAGGGCTTTTCGCTGCTCGTGGTGGAGCGCGGCATGGAGGGCTTCG
AGCGGGGACGGCACCTGGACAAGATCGGGCTGGACGCCCAGGACACCGCCGAGCTGTCCTTCACCGACGTGCACGTGCCC
GCCGAGAACCTGCTGGGCCAGGAGGGCATGGGATTCATCTACCTGATGCAGAACTTGCCGCAGGAACGGATCTCGATCGC
CGTCATGGCGGCCGCGGCGATGGAGCAGGTGCTGGAGCAGACGCTGGAATACACCAAGGAGCGCAAGGCATTCGGCAAGT
CCATCGGCAGCTTCCAGAACAGCCGGTTCGTGCTGGCCGAGCTGGCGACGGAGGCCACCGTGGTGCGCATGATGGTCGAC
GAGTTCGTCCGCCTGCACCTGGACCACAAGCTGACCGCCGAACAGGCCGCCATGGCCAAGTGGTACTCCACCGAAAAGCA
GGTGCACCTGATCGACCGCTGCCTGCAATTGCATGGCGGCTACGGCTACATGCGCGAATACCCGGTCGCCCGTGCCTATC
TGGATGCCCGGGTGCAGACCATTTACGGCGGCACCACCGAGATCATGAAGGAAATCATCGGCCGCAGCCTCGGCGTCTAG

Upstream 100 bases:

>100_bases
CCCGGATCAAGGCGCGCGTTCCGCTGGCCCTGGCCGGGCGGCTGCGCGAGTTCGCCGCCCCCTGACCCCGGCGGCTGCCG
ACCAACCGTCTGGTTGGTAT

Downstream 100 bases:

>100_bases
CGTTTCGCGCGGCCGGGGGCACGCCGGGTCGCGATTCGGACATGGCTCCGCATCGGTTCGACATCGATGCGGTATCCGTT
TTTGTAAAATTCGTAATTTG

Product: FadE20_2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MLGGSNPSRPEVVHEQRHQIPAHAFRVRTRTVPRVLPGLPRSSRRAVSRRMGEGEDRRPRGVARGRQAGLPGHGGARGVR
RRGQPRFPVQHHHHRGDHPRPLQRDRLRPAQRHRRALPAGPGHRGAEAALAAEILHRRTDYGDRDDRAGHRQRPAGHQDP
GGQAGRPLRAQRVKDVHHQRINSDLVIVVAQTDPDKGAQGFSLLVVERGMEGFERGRHLDKIGLDAQDTAELSFTDVHVP
AENLLGQEGMGFIYLMQNLPQERISIAVMAAAAMEQVLEQTLEYTKERKAFGKSIGSFQNSRFVLAELATEATVVRMMVD
EFVRLHLDHKLTAEQAAMAKWYSTEKQVHLIDRCLQLHGGYGYMREYPVARAYLDARVQTIYGGTTEIMKEIIGRSLGV

Sequences:

>Translated_399_residues
MLGGSNPSRPEVVHEQRHQIPAHAFRVRTRTVPRVLPGLPRSSRRAVSRRMGEGEDRRPRGVARGRQAGLPGHGGARGVR
RRGQPRFPVQHHHHRGDHPRPLQRDRLRPAQRHRRALPAGPGHRGAEAALAAEILHRRTDYGDRDDRAGHRQRPAGHQDP
GGQAGRPLRAQRVKDVHHQRINSDLVIVVAQTDPDKGAQGFSLLVVERGMEGFERGRHLDKIGLDAQDTAELSFTDVHVP
AENLLGQEGMGFIYLMQNLPQERISIAVMAAAAMEQVLEQTLEYTKERKAFGKSIGSFQNSRFVLAELATEATVVRMMVD
EFVRLHLDHKLTAEQAAMAKWYSTEKQVHLIDRCLQLHGGYGYMREYPVARAYLDARVQTIYGGTTEIMKEIIGRSLGV
>Mature_399_residues
MLGGSNPSRPEVVHEQRHQIPAHAFRVRTRTVPRVLPGLPRSSRRAVSRRMGEGEDRRPRGVARGRQAGLPGHGGARGVR
RRGQPRFPVQHHHHRGDHPRPLQRDRLRPAQRHRRALPAGPGHRGAEAALAAEILHRRTDYGDRDDRAGHRQRPAGHQDP
GGQAGRPLRAQRVKDVHHQRINSDLVIVVAQTDPDKGAQGFSLLVVERGMEGFERGRHLDKIGLDAQDTAELSFTDVHVP
AENLLGQEGMGFIYLMQNLPQERISIAVMAAAAMEQVLEQTLEYTKERKAFGKSIGSFQNSRFVLAELATEATVVRMMVD
EFVRLHLDHKLTAEQAAMAKWYSTEKQVHLIDRCLQLHGGYGYMREYPVARAYLDARVQTIYGGTTEIMKEIIGRSLGV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=217, Percent_Identity=52.5345622119816, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI7656849, Length=216, Percent_Identity=35.1851851851852, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI226958414, Length=218, Percent_Identity=33.9449541284404, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI226958412, Length=218, Percent_Identity=33.9449541284404, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI4501859, Length=211, Percent_Identity=34.1232227488152, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4557233, Length=208, Percent_Identity=34.1346153846154, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4557235, Length=223, Percent_Identity=31.8385650224215, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI76496475, Length=223, Percent_Identity=31.8385650224215, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI21361497, Length=221, Percent_Identity=31.2217194570136, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI4557231, Length=216, Percent_Identity=30.5555555555556, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI187960098, Length=216, Percent_Identity=30.5555555555556, Blast_Score=102, Evalue=5e-22,
Organism=Escherichia coli, GI87081958, Length=205, Percent_Identity=34.1463414634146, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1786223, Length=179, Percent_Identity=26.8156424581006, Blast_Score=85, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17533517, Length=217, Percent_Identity=36.405529953917, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17538396, Length=216, Percent_Identity=30.5555555555556, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17570075, Length=227, Percent_Identity=32.5991189427313, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=217, Percent_Identity=28.110599078341, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=215, Percent_Identity=31.1627906976744, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=216, Percent_Identity=29.1666666666667, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=211, Percent_Identity=28.436018957346, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=215, Percent_Identity=31.6279069767442, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=221, Percent_Identity=32.1266968325792, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=208, Percent_Identity=31.7307692307692, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=165, Percent_Identity=32.1212121212121, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=218, Percent_Identity=28.4403669724771, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=178, Percent_Identity=31.4606741573034, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=116, Percent_Identity=31.8965517241379, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=130, Percent_Identity=28.4615384615385, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21356377, Length=215, Percent_Identity=33.4883720930233, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24666513, Length=251, Percent_Identity=31.4741035856574, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI21355753, Length=220, Percent_Identity=33.6363636363636, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24646207, Length=211, Percent_Identity=32.2274881516588, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24660351, Length=219, Percent_Identity=31.5068493150685, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281363737, Length=224, Percent_Identity=31.6964285714286, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 44767; Mature: 44767

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGGSNPSRPEVVHEQRHQIPAHAFRVRTRTVPRVLPGLPRSSRRAVSRRMGEGEDRRPR
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
GVARGRQAGLPGHGGARGVRRRGQPRFPVQHHHHRGDHPRPLQRDRLRPAQRHRRALPAG
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCCCC
PGHRGAEAALAAEILHRRTDYGDRDDRAGHRQRPAGHQDPGGQAGRPLRAQRVKDVHHQR
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
INSDLVIVVAQTDPDKGAQGFSLLVVERGMEGFERGRHLDKIGLDAQDTAELSFTDVHVP
CCCCEEEEEEECCCCCCCCCCEEEHHHHCHHHHHHCCCHHHHCCCCCCCCCEEEEEEECC
AENLLGQEGMGFIYLMQNLPQERISIAVMAAAAMEQVLEQTLEYTKERKAFGKSIGSFQN
HHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SRFVLAELATEATVVRMMVDEFVRLHLDHKLTAEQAAMAKWYSTEKQVHLIDRCLQLHGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
YGYMREYPVARAYLDARVQTIYGGTTEIMKEIIGRSLGV
CCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLGGSNPSRPEVVHEQRHQIPAHAFRVRTRTVPRVLPGLPRSSRRAVSRRMGEGEDRRPR
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCC
GVARGRQAGLPGHGGARGVRRRGQPRFPVQHHHHRGDHPRPLQRDRLRPAQRHRRALPAG
HHHCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHCCCCC
PGHRGAEAALAAEILHRRTDYGDRDDRAGHRQRPAGHQDPGGQAGRPLRAQRVKDVHHQR
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
INSDLVIVVAQTDPDKGAQGFSLLVVERGMEGFERGRHLDKIGLDAQDTAELSFTDVHVP
CCCCEEEEEEECCCCCCCCCCEEEHHHHCHHHHHHCCCHHHHCCCCCCCCCEEEEEEECC
AENLLGQEGMGFIYLMQNLPQERISIAVMAAAAMEQVLEQTLEYTKERKAFGKSIGSFQN
HHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SRFVLAELATEATVVRMMVDEFVRLHLDHKLTAEQAAMAKWYSTEKQVHLIDRCLQLHGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCC
YGYMREYPVARAYLDARVQTIYGGTTEIMKEIIGRSLGV
CCHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]