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The map label for this gene is rnd [H]

Identifier: 41408900

GI number: 41408900

Start: 3131853

End: 3133139

Strand: Direct

Name: rnd [H]

Synonym: MAP2802

Alternate gene names: 41408900

Gene position: 3131853-3133139 (Clockwise)

Preceding gene: 41408899

Following gene: 41408902

Centisome position: 64.84

GC content: 74.59

Gene sequence:

>1287_bases
ATGGGCGAACCGTCGGCCGAGGGGCCGGGTAGCGGCGTGCCCGCTCCCATCCCGCTGCCGCACCCGTCCGAAGGCGTCCC
GCCGATCTCGGCCAGCGTGCCCGACATCGAGGACGCGGCGCGGCGGCTGGACCGCGGCCGCGGGCCGTTCGCGGTGGACG
CCGAGCGGGCGTCGGGATTCCGCTACTCCAACCGGGCCTACCTGATCCAGATCCGCAGGGCCGGGGCCGGCACCGTGCTG
ATCGACCCGGTGAGCCACGGCGCCGACCCGGTGCGAGCGCTGCGACCGGTGGCCGAGGTGCTCGGCAGCGACGAGTGGAT
TCTGCACTCCGCGGATCAGGACCTGCCCTGTCTGGCGGAGGTGGGCATGCGGCCGCCGGCGCTGTATGACACCGAGCTGG
CCGGTCGGCTGGCCGGGTTCGAGCGGGTGAACCTGGCGACCATGGTCGAGCGGCTGCTGGGCTTCGGGCTGGCCAAGGGC
CACGGCGCGGCCGACTGGTCCAAGCGCCCGCTGCCCGCCGAATGGCTCAACTACGCCGCCCTGGATGTGGAGCTGCTCAT
CGAGCTGCGCGCCGCGATCGCCGACGTGCTGGCGGAGCAGGGCAAAACCGATTGGGCCGCACAGGAATTCGACTATCTGC
GGGAGGCGGGTTCCAAGGAGCCGGGCCCCGCCGCGCGGCGCGACCGGTGGCGGCGGACGTCGGGAATCCATCGGGTGCGC
GATCAGCGCGGCCTGGCCGCGGTGCGCGAACTGTGGTTGACGCGCGACCGCATCGCGCAGCGCCGCGACATCGCCCCGCG
GCGCATCCTGCCCGACTCGGCGATCATCGAGGCCGCCCTGGCCAACCCGACGACCATCGAGGAGCTGGTGGCGCTGCCGG
TGTTCGGCGGGCGCAATCAACGGCGCAGCGCCGCGACCTGGTTGGCGGCGCTGGATGCGGCCCGGCAGAGCGAGAATCCG
CCGGTGGACTCCGAACCGCCGAACGGACCGCCGCCGCCGGCGCGGTGGAGCCGGCGCAAACCGGAGGCGGCCGCGCGGCT
GGAGGCCGCGCGCGCGGCGCTGGCCGAGGTGTCCGAACGCGTGCACGTCCCCACCGAGAACCTGGTCGCGCCGGACCTAG
TGCGACGGCTGTGCTGGGACTGGGAGCCCACCCCCGACCCGTTCGCGGCGGTCGACGCGTTCCTGTGCGCCGGGCACGCC
CGGCCCTGGCAGCGCGAATTGGTGGATCCGGTCCTGGCCCGGGCGCTGCAGCAGCCGCTGCCGGCGGTTGCGGACGACGA
CGGCTGA

Upstream 100 bases:

>100_bases
GTGGGCGCGCACGTGCAGGCGTTCTGCGAGGTGCTCGAGCACGCCGCGGGGCTGCCGCCCGCCGGAGTCACCGACCTGAG
CTCGCGGTCACGCGCCTAGC

Downstream 100 bases:

>100_bases
CGCGCACCGGCCGCGCCGGGCCGGGCGGGCGCTGAGACCCGTGACTAGTCGAGGTGCTCGCGGATCTCGGCCTCGGCCAC
GCCGCTGCCCAGCGCGGCGA

Product: hypothetical protein

Products: NA

Alternate protein names: RNase D [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MGEPSAEGPGSGVPAPIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAGAGTVL
IDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFERVNLATMVERLLGFGLAKG
HGAADWSKRPLPAEWLNYAALDVELLIELRAAIADVLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVR
DQRGLAAVRELWLTRDRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAARQSENP
PVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVRRLCWDWEPTPDPFAAVDAFLCAGHA
RPWQRELVDPVLARALQQPLPAVADDDG

Sequences:

>Translated_428_residues
MGEPSAEGPGSGVPAPIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAGAGTVL
IDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFERVNLATMVERLLGFGLAKG
HGAADWSKRPLPAEWLNYAALDVELLIELRAAIADVLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVR
DQRGLAAVRELWLTRDRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAARQSENP
PVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVRRLCWDWEPTPDPFAAVDAFLCAGHA
RPWQRELVDPVLARALQQPLPAVADDDG
>Mature_427_residues
GEPSAEGPGSGVPAPIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAGAGTVLI
DPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFERVNLATMVERLLGFGLAKGH
GAADWSKRPLPAEWLNYAALDVELLIELRAAIADVLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVRD
QRGLAAVRELWLTRDRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAARQSENPP
VDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVRRLCWDWEPTPDPFAAVDAFLCAGHAR
PWQRELVDPVLARALQQPLPAVADDDG

Specific function: Cleaves multimeric tRNA precursor at the spacer region. Contribute to the 3' maturation of several stable RNAs [H]

COG id: COG0349

COG function: function code J; Ribonuclease D

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Escherichia coli, GI1788105, Length=341, Percent_Identity=26.099706744868, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324574, Length=235, Percent_Identity=27.2340425531915, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI161078302, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002562
- InterPro:   IPR002121
- InterPro:   IPR010997
- InterPro:   IPR006292
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01612 3_5_exonuc; PF00570 HRDC [H]

EC number: =3.1.13.5 [H]

Molecular weight: Translated: 46592; Mature: 46461

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50967 HRDC ; PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEPSAEGPGSGVPAPIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCCC
RYSNRAYLIQIRRAGAGTVLIDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAE
EECCCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
VGMRPPALYDTELAGRLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
LDVELLIELRAAIADVLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DQRGLAAVRELWLTRDRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
RRSAATWLAALDAARQSENPPVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSER
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VHVPTENLVAPDLVRRLCWDWEPTPDPFAAVDAFLCAGHARPWQRELVDPVLARALQQPL
CCCCHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
PAVADDDG
CCCCCCCC
>Mature Secondary Structure 
GEPSAEGPGSGVPAPIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEHHHHCCC
RYSNRAYLIQIRRAGAGTVLIDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAE
EECCCEEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCHHHH
VGMRPPALYDTELAGRLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHH
LDVELLIELRAAIADVLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVR
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DQRGLAAVRELWLTRDRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQ
HHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
RRSAATWLAALDAARQSENPPVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSER
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
VHVPTENLVAPDLVRRLCWDWEPTPDPFAAVDAFLCAGHARPWQRELVDPVLARALQQPL
CCCCHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
PAVADDDG
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3041371; 9097040; 9278503; 8107670 [H]