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The map label for this gene is echA15

Identifier: 41408898

GI number: 41408898

Start: 3130285

End: 3131106

Strand: Direct

Name: echA15

Synonym: MAP2800

Alternate gene names: 41408898

Gene position: 3130285-3131106 (Clockwise)

Preceding gene: 41408893

Following gene: 41408899

Centisome position: 64.81

GC content: 70.19

Gene sequence:

>822_bases
GTGCCAGTCAGCCACCCGCCGGTCGATTACCACGACTTCCCCAGCCTGCGCTGCGAACTCGGCGACGACGGGGTGCTGAC
GGTGGTGCTCGACTCGCCGGGTCTGAATTCGGTGGGGCCGCAGATGCACCGCGACCTGGCCGACATCTGGCCGGTGATCG
ACCGCGACCCGGCGGTGCGCGCGGTGCTGGTCCGCGGTGAGGGCAAGGCCTTCTCCTCCGGCGGCAGCTTCGATTTGATC
GACGAGACCATCGGCGACTACCAGGGCCGGGTCCGCATCATGCGGGAGGCGCGCGACCTGGTGCACAACATGATCAACTG
CGACACCCCGGTGGTGTCGGCGATCCGCGGGCCGGCCGTGGGCGCGGGCCTGGTGGTGGCCCTGCTCGCCGACATCTCGG
TGGCCGGCCGCACCGCCAAGCTGATCGACGGGCACACCAAGCTGGGCGTGGCCGCCGGCGACCACGCCGCCATCTGCTGG
CCGCTGCTGGTCGGCATGGCCAAGGCCAAGTACTACCTGCTGACCTGCGAGACGCTGCTCGGCGAGGAGGCCGAGCGGAT
CGGCCTGGTGTCGCTGTGCGTCGACGACGACGACGTGCTGTCCACCGCCGCGGGCATCGCCGGGAAACTGGCGCAGGGCG
CCCAGCACGCCATCCAATGGACCAAGCGCAGCCTCAACCACTGGTACCGCATGATGGGCCCCACCTTCGAGACCTCGGTG
GGGCTGGAATTCCTCAGTTTCAGCGGGCCCGACGTGCAGGAAGGCCTGGCCGCGCACCGGGAGAAACGCGCCGCCCGCTT
CACCGGCGGATCTGCCACCTGA

Upstream 100 bases:

>100_bases
GCCAGATACGGCGACTCGGGAAGGTCGCGGCGGGTACGCGCGCTGCTGTTCATCGGGCTCAATGCTGCCATGACGGCGTC
GCTGCGTAGTATCGACGACC

Downstream 100 bases:

>100_bases
GCTGGACATATAGCTTTGGTGGAGGCCCGGTAACGGCTTGGTCGCGGCGGGTGTATAACCCGGCGCGCCTGTCGCGGCGT
GTCGGCCGATGGGTCTACCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MPVSHPPVDYHDFPSLRCELGDDGVLTVVLDSPGLNSVGPQMHRDLADIWPVIDRDPAVRAVLVRGEGKAFSSGGSFDLI
DETIGDYQGRVRIMREARDLVHNMINCDTPVVSAIRGPAVGAGLVVALLADISVAGRTAKLIDGHTKLGVAAGDHAAICW
PLLVGMAKAKYYLLTCETLLGEEAERIGLVSLCVDDDDVLSTAAGIAGKLAQGAQHAIQWTKRSLNHWYRMMGPTFETSV
GLEFLSFSGPDVQEGLAAHREKRAARFTGGSAT

Sequences:

>Translated_273_residues
MPVSHPPVDYHDFPSLRCELGDDGVLTVVLDSPGLNSVGPQMHRDLADIWPVIDRDPAVRAVLVRGEGKAFSSGGSFDLI
DETIGDYQGRVRIMREARDLVHNMINCDTPVVSAIRGPAVGAGLVVALLADISVAGRTAKLIDGHTKLGVAAGDHAAICW
PLLVGMAKAKYYLLTCETLLGEEAERIGLVSLCVDDDDVLSTAAGIAGKLAQGAQHAIQWTKRSLNHWYRMMGPTFETSV
GLEFLSFSGPDVQEGLAAHREKRAARFTGGSAT
>Mature_272_residues
PVSHPPVDYHDFPSLRCELGDDGVLTVVLDSPGLNSVGPQMHRDLADIWPVIDRDPAVRAVLVRGEGKAFSSGGSFDLID
ETIGDYQGRVRIMREARDLVHNMINCDTPVVSAIRGPAVGAGLVVALLADISVAGRTAKLIDGHTKLGVAAGDHAAICWP
LLVGMAKAKYYLLTCETLLGEEAERIGLVSLCVDDDDVLSTAAGIAGKLAQGAQHAIQWTKRSLNHWYRMMGPTFETSVG
LEFLSFSGPDVQEGLAAHREKRAARFTGGSAT

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=252, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1787660, Length=258, Percent_Identity=31.0077519379845, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788597, Length=278, Percent_Identity=23.7410071942446, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI221142681, Length=216, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787659, Length=247, Percent_Identity=25.1012145748988, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=249, Percent_Identity=26.9076305220884, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=256, Percent_Identity=26.5625, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540306, Length=254, Percent_Identity=27.5590551181102, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=207, Percent_Identity=28.5024154589372, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17534483, Length=231, Percent_Identity=26.8398268398268, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=27.9816513761468, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI20129971, Length=276, Percent_Identity=26.8115942028986, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653477, Length=276, Percent_Identity=26.8115942028986, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653139, Length=256, Percent_Identity=25.78125, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 29140; Mature: 29008

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00166 ENOYL_COA_HYDRATASE ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSHPPVDYHDFPSLRCELGDDGVLTVVLDSPGLNSVGPQMHRDLADIWPVIDRDPAVR
CCCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
AVLVRGEGKAFSSGGSFDLIDETIGDYQGRVRIMREARDLVHNMINCDTPVVSAIRGPAV
EEEEECCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
GAGLVVALLADISVAGRTAKLIDGHTKLGVAAGDHAAICWPLLVGMAKAKYYLLTCETLL
HHHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEHHHHH
GEEAERIGLVSLCVDDDDVLSTAAGIAGKLAQGAQHAIQWTKRSLNHWYRMMGPTFETSV
CCHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
GLEFLSFSGPDVQEGLAAHREKRAARFTGGSAT
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PVSHPPVDYHDFPSLRCELGDDGVLTVVLDSPGLNSVGPQMHRDLADIWPVIDRDPAVR
CCCCCCCCCCCCCCEEEECCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCEE
AVLVRGEGKAFSSGGSFDLIDETIGDYQGRVRIMREARDLVHNMINCDTPVVSAIRGPAV
EEEEECCCCEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCC
GAGLVVALLADISVAGRTAKLIDGHTKLGVAAGDHAAICWPLLVGMAKAKYYLLTCETLL
HHHHHHHHHHHHHHCCCCHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEHHHHH
GEEAERIGLVSLCVDDDDVLSTAAGIAGKLAQGAQHAIQWTKRSLNHWYRMMGPTFETSV
CCHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
GLEFLSFSGPDVQEGLAAHREKRAARFTGGSAT
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]