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The map label for this gene is sigE

Identifier: 41408655

GI number: 41408655

Start: 2874942

End: 2875697

Strand: Reverse

Name: sigE

Synonym: MAP2557c

Alternate gene names: 41408655

Gene position: 2875697-2874942 (Counterclockwise)

Preceding gene: 41408662

Following gene: 41408654

Centisome position: 59.54

GC content: 68.92

Gene sequence:

>756_bases
ATGGATCGCGGAGCGCGGGAGACCGGGAATACCGAATGGCAGCTGCCTGTTGCCGCCAATGACGAAATGCCGCTGATCGG
CATGCCGAATTCGGAGGAATTGATCATCACCACGCTTTTGAGCCCGTCCAGCATGTCGCACGCGCACGACCCTTCCGCCG
ACGGGTGGGCGGAGCCGTCCGACGGGCTGCAGGGCACCGCGGTCTTCGACGCGACCGGTGACAAGACGGCCATGCCGTCG
TGGGACGAGCTGGTGCGCCAGCACGCCGACCGGGTGTACCGGCTGGCCTACCGGCTTTCCGGCAATCAGCACGACGCCGA
GGACCTCACCCAGGAGACCTTCATCCGGGTGTTCCGGTCGGTGCAGAACTACCAGCCGGGAACCTTCGAGGGCTGGCTGC
ACCGCATCACCACGAACCTGTTCCTGGACATGGTCCGCCGGCGCTCGCGCATCCGGATGGAGGCGCTGCCCGAGGACTAC
GAGCGGGTGCCCGCCGACGAGCCCAATCCCGAAGAGATCTACCACGATTCGCGGCTCGGCCCCGACCTGCAGGCCGCGCT
GGACTCGCTGCCGCCGGAGTTCCGCGCCGCGGTCGTGCTGTGCGACATCGAGGGCCTGTCGTATGAGGAGATCGGCGCGA
CGCTGGGGGTGAAGCTGGGCACCGTGCGCAGCCGCATCCACCGCGGCCGCCAGGCCCTGCGCGATTACCTGGCCGCGCAC
CCCGACCACGACGCGCTGCGCGCCTCCTCGGCGTAG

Upstream 100 bases:

>100_bases
GATGGATGTCTCCTGCACAGCGCAGGTAACGAAAAGGTTTCTCAGGCTCAGCTCAGATTGTTCATATACCGCACATACGC
CGATACGCGACGGTGTCCGT

Downstream 100 bases:

>100_bases
TCAGCGCCCGCCCGGCTAACGTTCGGGCAGCTATTCAGCGGCTTTGCGGCCTTGGCGTCGGTATCGGGCGCCGTGTCGCG
CTACATTCGAAGAAGGCGAA

Product: RNA polymerase sigma factor SigE

Products: NA

Alternate protein names: Sigma-W factor [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MDRGARETGNTEWQLPVAANDEMPLIGMPNSEELIITTLLSPSSMSHAHDPSADGWAEPSDGLQGTAVFDATGDKTAMPS
WDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHRITTNLFLDMVRRRSRIRMEALPEDY
ERVPADEPNPEEIYHDSRLGPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAH
PDHDALRASSA

Sequences:

>Translated_251_residues
MDRGARETGNTEWQLPVAANDEMPLIGMPNSEELIITTLLSPSSMSHAHDPSADGWAEPSDGLQGTAVFDATGDKTAMPS
WDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHRITTNLFLDMVRRRSRIRMEALPEDY
ERVPADEPNPEEIYHDSRLGPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAH
PDHDALRASSA
>Mature_251_residues
MDRGARETGNTEWQLPVAANDEMPLIGMPNSEELIITTLLSPSSMSHAHDPSADGWAEPSDGLQGTAVFDATGDKTAMPS
WDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLHRITTNLFLDMVRRRSRIRMEALPEDY
ERVPADEPNPEEIYHDSRLGPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAH
PDHDALRASSA

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-W controls genes involved in transport processes and detoxification [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=171, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR014294
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 28134; Mature: 28134

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRGARETGNTEWQLPVAANDEMPLIGMPNSEELIITTLLSPSSMSHAHDPSADGWAEPS
CCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
DGLQGTAVFDATGDKTAMPSWDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRS
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VQNYQPGTFEGWLHRITTNLFLDMVRRRSRIRMEALPEDYERVPADEPNPEEIYHDSRLG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHCCCCC
PDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAH
CHHHHHHHHCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDHDALRASSA
CCHHHHHCCCC
>Mature Secondary Structure
MDRGARETGNTEWQLPVAANDEMPLIGMPNSEELIITTLLSPSSMSHAHDPSADGWAEPS
CCCCCCCCCCCCEEEEEECCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
DGLQGTAVFDATGDKTAMPSWDELVRQHADRVYRLAYRLSGNQHDAEDLTQETFIRVFRS
CCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
VQNYQPGTFEGWLHRITTNLFLDMVRRRSRIRMEALPEDYERVPADEPNPEEIYHDSRLG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCHHHHHHCCCCC
PDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGATLGVKLGTVRSRIHRGRQALRDYLAAH
CHHHHHHHHCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDHDALRASSA
CCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274029; 9384377; 12207695 [H]