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The map label for this gene is 41408523

Identifier: 41408523

GI number: 41408523

Start: 2721828

End: 2722271

Strand: Reverse

Name: 41408523

Synonym: MAP2425c

Alternate gene names: NA

Gene position: 2722271-2721828 (Counterclockwise)

Preceding gene: 41408524

Following gene: 41408522

Centisome position: 56.36

GC content: 70.72

Gene sequence:

>444_bases
ATGGCCAACACCGTGCCGCTGCTGGTGCTCGGATTCCTGATGACGCTGGCCGGGCTGGCCCGGTTCGTCTGGGCGACCGT
GATCATCTGGATCGTGGGGGGTTTCGGCACCTGGCTGATCGGCAACGTCGGCAGCAGTTGCGGGCCCACCGACCACATCG
GGGCCTCCGGCCTGATCTTCGGCTGGCTGGCCTTCCTGCTGGTGTTCGGCATCTTCGTGCGCCGGGTCCGCGACATCATC
ATCGGCCTGGCGGTCATGTTCGCCTACGGCGGCGTGCTGCTCGGCGCCATGCCGGTGCTCGGCCTGTGCGGCGGCGTGTC
CTGGCAGGGCCACCTGTGCGGGGCGATCGCCGGCGTGCTGGCCGCCTACCTGCTGTCCGAACCGGAACGCAAGGGCCGCT
CCGGCCGCAAGACCGGCGCCGGCGCGCCGCGCCCCAAGACATGA

Upstream 100 bases:

>100_bases
CCGCCACGCCCTGGACGTCCACGGCATCCGGCCGCAGCGGGTCGACGGCCTGTGGGGCATCGTCTTCGCCCCGGTGCTGC
ACGAGAGCTGACAGCACCTG

Downstream 100 bases:

>100_bases
GCTCGGCACTGGCGCCCGTCGGGATCTTCGACTCCGGCGTCGGCGGACTGACCGTCGCGCGGGCCATCATCGACCAGCTG
CCCGACGAGCACATCATTTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MANTVPLLVLGFLMTLAGLARFVWATVIIWIVGGFGTWLIGNVGSSCGPTDHIGASGLIFGWLAFLLVFGIFVRRVRDII
IGLAVMFAYGGVLLGAMPVLGLCGGVSWQGHLCGAIAGVLAAYLLSEPERKGRSGRKTGAGAPRPKT

Sequences:

>Translated_147_residues
MANTVPLLVLGFLMTLAGLARFVWATVIIWIVGGFGTWLIGNVGSSCGPTDHIGASGLIFGWLAFLLVFGIFVRRVRDII
IGLAVMFAYGGVLLGAMPVLGLCGGVSWQGHLCGAIAGVLAAYLLSEPERKGRSGRKTGAGAPRPKT
>Mature_146_residues
ANTVPLLVLGFLMTLAGLARFVWATVIIWIVGGFGTWLIGNVGSSCGPTDHIGASGLIFGWLAFLLVFGIFVRRVRDIII
GLAVMFAYGGVLLGAMPVLGLCGGVSWQGHLCGAIAGVLAAYLLSEPERKGRSGRKTGAGAPRPKT

Specific function: Unknown

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1171 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022764 [H]

Pfam domain/function: PF01694 Rhomboid [H]

EC number: NA

Molecular weight: Translated: 15299; Mature: 15167

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTVPLLVLGFLMTLAGLARFVWATVIIWIVGGFGTWLIGNVGSSCGPTDHIGASGLIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
GWLAFLLVFGIFVRRVRDIIIGLAVMFAYGGVLLGAMPVLGLCGGVSWQGHLCGAIAGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AAYLLSEPERKGRSGRKTGAGAPRPKT
HHHHHCCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANTVPLLVLGFLMTLAGLARFVWATVIIWIVGGFGTWLIGNVGSSCGPTDHIGASGLIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
GWLAFLLVFGIFVRRVRDIIIGLAVMFAYGGVLLGAMPVLGLCGGVSWQGHLCGAIAGVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AAYLLSEPERKGRSGRKTGAGAPRPKT
HHHHHCCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]