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The map label for this gene is echA8 [H]

Identifier: 41408493

GI number: 41408493

Start: 2690918

End: 2691808

Strand: Reverse

Name: echA8 [H]

Synonym: MAP2395c

Alternate gene names: 41408493

Gene position: 2691808-2690918 (Counterclockwise)

Preceding gene: 41408494

Following gene: 41408491

Centisome position: 55.73

GC content: 67.68

Gene sequence:

>891_bases
ATGACCGCCTCGAGCACCTCCGACGATCGCGTGCTCTTCGACGTCGACGCCGAGCACCGCATCGCGACGATCACGCTGAA
CAATCCCAAGCAGCGCAACTCCTACGACGCCGCCATGCGCGAGGCCATCGCCCGCTGCCTGGATCGCGTCGCCGAGGACG
ACGATCTCACCGTCGTGCTGCTGCGCGGGGCCGAGGGGGTCTTTTCCACCGGGGCCGACATGAACAACGCCTACGGCTGG
TACGGCACGTCACGCAACGCGGACGAGTCCACCCGGCGCCGCCCCAGCCAGCGTCGGCGACTCACGGTGGACCGCAAGTC
TTTTGGCTTCTACCACAATTTCATGGGCTTCCCGAAGGTGACGGTCGGCGAGATCGCCGGCTACGCGCTCGGCGGCGGCT
TCGAGATGGCGCTGATGACCGACATCTCGGTGATCGCGCGGGACACCAAGATCGGCATGCCGGCCACCCGCTTCCTGGGC
CCCGCGCTCGGCAGCCTGCACATGTTCTTCCACCGGCTGGGGCCGGTGCTGGCCCGGCGCCTGCTGCTGACCGGCGACAT
CATCGACGCCGGGCAGGTCGAACACCTCGGAATCTTCACCGACACCTGCGATCCCGCTGCGGTGACGGCCCGGGCGCGCT
ACTGGGCCGAGAAGGCGGCGAAGATGCCCGCCGATGGGGTGGTGATCGCCAAGGAGGCCTTCCGGCTGGTCGAGCAGAGC
CAGGCATATCAGGGCGAGGAGGTCGCCAGCTATCTGTTCCATGCCTTCGGCACCAACCTGCAATTCGCCCCGGGGGAGTT
CAACTTCGTCAAGTCCCGCGCCGAGCACGGCGCCAAGGAAGCGTTCCGGCTTCGCGACGAGCACTTCCACGTGCCGGAAC
CGGAGGCGTGA

Upstream 100 bases:

>100_bases
GCGACGACGTGCTGTGCACCGGCGAGGTCAACACGTTGGCGTCGCGCCCGGATCAGCTCGCCGGGTCGCGATTCGGCCGG
CGCCGAAAGGAGTCCGACAC

Downstream 100 bases:

>100_bases
CAAGCCTTTTCGGGAACGGTCAGCGATTCGCCGGCGCCTTGGTGCGGCCCCGCGCGGCCGACGACTTGGCGGGCTTGCGC
TGTCGCGAGGGCCCGGCCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTASSTSDDRVLFDVDAEHRIATITLNNPKQRNSYDAAMREAIARCLDRVAEDDDLTVVLLRGAEGVFSTGADMNNAYGW
YGTSRNADESTRRRPSQRRRLTVDRKSFGFYHNFMGFPKVTVGEIAGYALGGGFEMALMTDISVIARDTKIGMPATRFLG
PALGSLHMFFHRLGPVLARRLLLTGDIIDAGQVEHLGIFTDTCDPAAVTARARYWAEKAAKMPADGVVIAKEAFRLVEQS
QAYQGEEVASYLFHAFGTNLQFAPGEFNFVKSRAEHGAKEAFRLRDEHFHVPEPEA

Sequences:

>Translated_296_residues
MTASSTSDDRVLFDVDAEHRIATITLNNPKQRNSYDAAMREAIARCLDRVAEDDDLTVVLLRGAEGVFSTGADMNNAYGW
YGTSRNADESTRRRPSQRRRLTVDRKSFGFYHNFMGFPKVTVGEIAGYALGGGFEMALMTDISVIARDTKIGMPATRFLG
PALGSLHMFFHRLGPVLARRLLLTGDIIDAGQVEHLGIFTDTCDPAAVTARARYWAEKAAKMPADGVVIAKEAFRLVEQS
QAYQGEEVASYLFHAFGTNLQFAPGEFNFVKSRAEHGAKEAFRLRDEHFHVPEPEA
>Mature_295_residues
TASSTSDDRVLFDVDAEHRIATITLNNPKQRNSYDAAMREAIARCLDRVAEDDDLTVVLLRGAEGVFSTGADMNNAYGWY
GTSRNADESTRRRPSQRRRLTVDRKSFGFYHNFMGFPKVTVGEIAGYALGGGFEMALMTDISVIARDTKIGMPATRFLGP
ALGSLHMFFHRLGPVLARRLLLTGDIIDAGQVEHLGIFTDTCDPAAVTARARYWAEKAAKMPADGVVIAKEAFRLVEQSQ
AYQGEEVASYLFHAFGTNLQFAPGEFNFVKSRAEHGAKEAFRLRDEHFHVPEPEA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI1787659, Length=236, Percent_Identity=26.271186440678, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787660, Length=222, Percent_Identity=28.3783783783784, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=181, Percent_Identity=27.0718232044199, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24653139, Length=186, Percent_Identity=30.1075268817204, Blast_Score=81, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 32802; Mature: 32671

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASSTSDDRVLFDVDAEHRIATITLNNPKQRNSYDAAMREAIARCLDRVAEDDDLTVVL
CCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
LRGAEGVFSTGADMNNAYGWYGTSRNADESTRRRPSQRRRLTVDRKSFGFYHNFMGFPKV
EECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCEEECHHHHHHHHHHCCCCCC
TVGEIAGYALGGGFEMALMTDISVIARDTKIGMPATRFLGPALGSLHMFFHRLGPVLARR
HHHHHHCEEECCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLTGDIIDAGQVEHLGIFTDTCDPAAVTARARYWAEKAAKMPADGVVIAKEAFRLVEQS
HHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHH
QAYQGEEVASYLFHAFGTNLQFAPGEFNFVKSRAEHGAKEAFRLRDEHFHVPEPEA
HCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TASSTSDDRVLFDVDAEHRIATITLNNPKQRNSYDAAMREAIARCLDRVAEDDDLTVVL
CCCCCCCCEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEE
LRGAEGVFSTGADMNNAYGWYGTSRNADESTRRRPSQRRRLTVDRKSFGFYHNFMGFPKV
EECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCHHHHCEEECHHHHHHHHHHCCCCCC
TVGEIAGYALGGGFEMALMTDISVIARDTKIGMPATRFLGPALGSLHMFFHRLGPVLARR
HHHHHHCEEECCCEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LLLTGDIIDAGQVEHLGIFTDTCDPAAVTARARYWAEKAAKMPADGVVIAKEAFRLVEQS
HHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHH
QAYQGEEVASYLFHAFGTNLQFAPGEFNFVKSRAEHGAKEAFRLRDEHFHVPEPEA
HCCCHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]