BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

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The map label for this gene is yciK [C]

Identifier: 41408468

GI number: 41408468

Start: 2663852

End: 2664676

Strand: Reverse

Name: yciK [C]

Synonym: MAP2370c

Alternate gene names: 41408468

Gene position: 2664676-2663852 (Counterclockwise)

Preceding gene: 41408469

Following gene: 41408467

Centisome position: 55.17

GC content: 67.15

Gene sequence:

>825_bases
ATGACGCGCAGGACGATTGTCATCACGGGCGCCAGCGACGGCATCGGCGCGGCCGCGGCTCGTCGCCTCAGCCGCGCCGG
CGACCGGATCGTCGTGGTCGGCCGCTCCCAAACCAAGACCGCCGCGGTGGCCGCCGAATTGGGCGCCGATCACTTCGTCG
TCGATTACGCCGACCTGTCCCAGGTGCGGGCGCTGGCGGACAAGATGCGTGCGCAATACCCGCGCATCGACGTGTTGCTC
AACAACGCGGGCGGGGTGGCCAGCAGGATCGAGCTGACGGCCGACGGCTACGAACGCACCTATCAGGTCAACTACCTGGC
GCCGTTCCTGTTGACCACCCAGTTGCTGGATGTGCTGCTGGAGTCCCGGGCCACGGTCGTCAACACGACCAGCTCCTCGC
ACAAGCTGATCCTCCGTGCCACCGTCGACGACCTGGAGAACACCGCCAACCGCAGGCCCGCCGTCGCTTACGCGTACTCG
AAGCTGGCAATCGTGTTGTTCACCAAGGAATTACACCGGCGCTACCACGCGCGCGGCCTTTCCGTTGCGGCCGTGCATCC
CGGCAACGTCAACTCCAACATCGGCATCGCCTCGGGTTCGCGATTTCTGGTGTTCATGCAGCGGTACACCCCGGCGGCGC
TGTTCATCTCGAGCCCGGACCAGGGCGCCGACCCCTTGGTGCGGCTGGCCTCGAGCCCGCCCGATTCGGAGTGGACGTCC
GGCGCGTACTACGCCAAGCGCAAGATCGGCAAAACCACTCGCCTGGCGGACGATCCGCGATTGGCCGCCGAACTGTGGGA
GCGCACCGCGGCCAGGCTCGGCTGA

Upstream 100 bases:

>100_bases
CGGCGGCCTCAAGCACCTGCCGGTGCGGTATTCGCTGGCGTGAGTCGGGGTCAGGCCGCCACCTCTGCGTGATCGCTACA
CTCCCGGTGGAGGTCTGGCA

Downstream 100 bases:

>100_bases
CGAGCTCCCGGGGTCGGCGGAGGACCGCCCGGGTGATCTTCGATACTCGCTGGTATCTATCAGATACTGGCCGGTATGCT
GCTGGGCATGTCGCCCGTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTRRTIVITGASDGIGAAAARRLSRAGDRIVVVGRSQTKTAAVAAELGADHFVVDYADLSQVRALADKMRAQYPRIDVLL
NNAGGVASRIELTADGYERTYQVNYLAPFLLTTQLLDVLLESRATVVNTTSSSHKLILRATVDDLENTANRRPAVAYAYS
KLAIVLFTKELHRRYHARGLSVAAVHPGNVNSNIGIASGSRFLVFMQRYTPAALFISSPDQGADPLVRLASSPPDSEWTS
GAYYAKRKIGKTTRLADDPRLAAELWERTAARLG

Sequences:

>Translated_274_residues
MTRRTIVITGASDGIGAAAARRLSRAGDRIVVVGRSQTKTAAVAAELGADHFVVDYADLSQVRALADKMRAQYPRIDVLL
NNAGGVASRIELTADGYERTYQVNYLAPFLLTTQLLDVLLESRATVVNTTSSSHKLILRATVDDLENTANRRPAVAYAYS
KLAIVLFTKELHRRYHARGLSVAAVHPGNVNSNIGIASGSRFLVFMQRYTPAALFISSPDQGADPLVRLASSPPDSEWTS
GAYYAKRKIGKTTRLADDPRLAAELWERTAARLG
>Mature_273_residues
TRRTIVITGASDGIGAAAARRLSRAGDRIVVVGRSQTKTAAVAAELGADHFVVDYADLSQVRALADKMRAQYPRIDVLLN
NAGGVASRIELTADGYERTYQVNYLAPFLLTTQLLDVLLESRATVVNTTSSSHKLILRATVDDLENTANRRPAVAYAYSK
LAIVLFTKELHRRYHARGLSVAAVHPGNVNSNIGIASGSRFLVFMQRYTPAALFISSPDQGADPLVRLASSPPDSEWTSG
AYYAKRKIGKTTRLADDPRLAAELWERTAARLG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI10190746, Length=294, Percent_Identity=32.6530612244898, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI166795268, Length=279, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI225579078, Length=283, Percent_Identity=34.6289752650177, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI193804850, Length=287, Percent_Identity=31.3588850174216, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI186928839, Length=279, Percent_Identity=32.9749103942652, Blast_Score=114, Evalue=6e-26,
Organism=Homo sapiens, GI7706523, Length=260, Percent_Identity=34.2307692307692, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI146231950, Length=278, Percent_Identity=33.8129496402878, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI19923931, Length=226, Percent_Identity=35.3982300884956, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI4502599, Length=290, Percent_Identity=25.5172413793103, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI13375997, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI72534732, Length=139, Percent_Identity=30.2158273381295, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI20149619, Length=218, Percent_Identity=26.605504587156, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787526, Length=199, Percent_Identity=32.6633165829146, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787335, Length=192, Percent_Identity=24.4791666666667, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI2367365, Length=255, Percent_Identity=26.2745098039216, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17558006, Length=282, Percent_Identity=31.2056737588652, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17532805, Length=295, Percent_Identity=28.135593220339, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115533172, Length=203, Percent_Identity=35.9605911330049, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533174, Length=203, Percent_Identity=35.9605911330049, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17532791, Length=292, Percent_Identity=27.0547945205479, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193207620, Length=298, Percent_Identity=26.8456375838926, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71992402, Length=292, Percent_Identity=29.4520547945205, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565532, Length=207, Percent_Identity=29.4685990338164, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17505416, Length=272, Percent_Identity=24.2647058823529, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535059, Length=287, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI72001364, Length=259, Percent_Identity=27.7992277992278, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=248, Percent_Identity=24.5967741935484, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=211, Percent_Identity=26.5402843601896, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193204405, Length=211, Percent_Identity=23.696682464455, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324820, Length=313, Percent_Identity=27.4760383386581, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24656154, Length=287, Percent_Identity=31.7073170731707, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI19922628, Length=287, Percent_Identity=31.7073170731707, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647946, Length=277, Percent_Identity=29.6028880866426, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI45553409, Length=277, Percent_Identity=29.6028880866426, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24647948, Length=277, Percent_Identity=29.6028880866426, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI45554248, Length=252, Percent_Identity=32.1428571428571, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24640117, Length=252, Percent_Identity=32.1428571428571, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24647931, Length=304, Percent_Identity=29.9342105263158, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20129347, Length=281, Percent_Identity=28.1138790035587, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI22024069, Length=290, Percent_Identity=29.6551724137931, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24586328, Length=282, Percent_Identity=28.7234042553192, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI161076371, Length=282, Percent_Identity=28.0141843971631, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28573296, Length=287, Percent_Identity=30.3135888501742, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=29.6875, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19921754, Length=288, Percent_Identity=26.7361111111111, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=31.5, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24644339, Length=200, Percent_Identity=29.5, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357041, Length=194, Percent_Identity=29.8969072164948, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 29757; Mature: 29626

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRTIVITGASDGIGAAAARRLSRAGDRIVVVGRSQTKTAAVAAELGADHFVVDYADLS
CCCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCEEEEEHHHHH
QVRALADKMRAQYPRIDVLLNNAGGVASRIELTADGYERTYQVNYLAPFLLTTQLLDVLL
HHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHH
ESRATVVNTTSSSHKLILRATVDDLENTANRRPAVAYAYSKLAIVLFTKELHRRYHARGL
HCCCEEEEECCCCCEEEEEEEHHHHHHHCCCCCEEEEHHHHEEEEEEHHHHHHHHHHCCC
SVAAVHPGNVNSNIGIASGSRFLVFMQRYTPAALFISSPDQGADPLVRLASSPPDSEWTS
EEEEECCCCCCCCCEEECCCEEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCC
GAYYAKRKIGKTTRLADDPRLAAELWERTAARLG
CHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRRTIVITGASDGIGAAAARRLSRAGDRIVVVGRSQTKTAAVAAELGADHFVVDYADLS
CCEEEEEECCCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCEEEEEHHHHH
QVRALADKMRAQYPRIDVLLNNAGGVASRIELTADGYERTYQVNYLAPFLLTTQLLDVLL
HHHHHHHHHHHCCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHH
ESRATVVNTTSSSHKLILRATVDDLENTANRRPAVAYAYSKLAIVLFTKELHRRYHARGL
HCCCEEEEECCCCCEEEEEEEHHHHHHHCCCCCEEEEHHHHEEEEEEHHHHHHHHHHCCC
SVAAVHPGNVNSNIGIASGSRFLVFMQRYTPAALFISSPDQGADPLVRLASSPPDSEWTS
EEEEECCCCCCCCCEEECCCEEEEEEECCCCEEEEEECCCCCCCHHHHCCCCCCCCCCCC
GAYYAKRKIGKTTRLADDPRLAAELWERTAARLG
CHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]