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The map label for this gene is xerC [H]

Identifier: 41408246

GI number: 41408246

Start: 2378957

End: 2379640

Strand: Direct

Name: xerC [H]

Synonym: MAP2148

Alternate gene names: 41408246

Gene position: 2378957-2379640 (Clockwise)

Preceding gene: 41408242

Following gene: 41408248

Centisome position: 49.26

GC content: 65.5

Gene sequence:

>684_bases
TTGTCGAAGTCCCGGGACCTCGCCTTGAAGCGGTATGCGAAATGGCTGGTTGATGAAGGCGAGCTTAGCTCCGATCCCCT
ACTAGGACTCAAACCGCCCAAGGGTGACCAGAAGGTGGTCAACGCCCTCACCGAAGATCAGCTCAAACGGCTGATCGCAG
CCTGCCAGGGCAAATCCCTAATGGACCGCCGCGACGAGACGATAGTCCGCCTCATGGCCGAGACCGGACTACGCGCCAAT
GAGACCCTCAGCCTGCAGATCACCGACGTCAACCTCGACGCCGGGATCGTGACGATTGTCCGCGGCAAGGGCGGCAAGGG
CCGCGTATCGCCCTTCAGCGTGCAGACCGCCACCGCCATCGACCGCTACCTTCGGGCACGGCGTGCGCATCGGCTGTCCA
ACACCGGGGCGCTGTGGCTGGGCGGGGGCGGGAAGAGCCTGGGGTACTACGGGCTGAGCAAGGCATTGAAGCAGCGCGCT
ACCGCCGCCGGCATCGAGACCTTCCACTTGCACATGCTCAGGCACACCGCCGCGACCCGCTGGCTACGCGCTGGCGGGTC
GGAGTCGGGGCTGATGAGCGTGGCCGGGTGGAAGAACCGCAGCATGATTGACAGGTACGTCGGCGCCGCTGCCGCCAGCC
TTGCCGCCGACGAGGCCCGCAGGCTCAACTTGGGCGATATCTGA

Upstream 100 bases:

>100_bases
CCGCCTGCGCCGCCGGGCCGTCGACCACCACCGACAACGGCGCGAAAGCGATCGCGGCGGCCGCCAGAATCCGGAGTCGG
CTCAATTTTGCGGGCATCAG

Downstream 100 bases:

>100_bases
GCTGGCACTTTCCAAAGTGTTACTGCGACTTTGGGGAATGTGACACTTTCCGCTTGAGCACGGCTGGTCAACGCTGTAGC
TTTGCAGCCGTACCTAAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MSKSRDLALKRYAKWLVDEGELSSDPLLGLKPPKGDQKVVNALTEDQLKRLIAACQGKSLMDRRDETIVRLMAETGLRAN
ETLSLQITDVNLDAGIVTIVRGKGGKGRVSPFSVQTATAIDRYLRARRAHRLSNTGALWLGGGGKSLGYYGLSKALKQRA
TAAGIETFHLHMLRHTAATRWLRAGGSESGLMSVAGWKNRSMIDRYVGAAAASLAADEARRLNLGDI

Sequences:

>Translated_227_residues
MSKSRDLALKRYAKWLVDEGELSSDPLLGLKPPKGDQKVVNALTEDQLKRLIAACQGKSLMDRRDETIVRLMAETGLRAN
ETLSLQITDVNLDAGIVTIVRGKGGKGRVSPFSVQTATAIDRYLRARRAHRLSNTGALWLGGGGKSLGYYGLSKALKQRA
TAAGIETFHLHMLRHTAATRWLRAGGSESGLMSVAGWKNRSMIDRYVGAAAASLAADEARRLNLGDI
>Mature_226_residues
SKSRDLALKRYAKWLVDEGELSSDPLLGLKPPKGDQKVVNALTEDQLKRLIAACQGKSLMDRRDETIVRLMAETGLRANE
TLSLQITDVNLDAGIVTIVRGKGGKGRVSPFSVQTATAIDRYLRARRAHRLSNTGALWLGGGGKSLGYYGLSKALKQRAT
AAGIETFHLHMLRHTAATRWLRAGGSESGLMSVAGWKNRSMIDRYVGAAAASLAADEARRLNLGDI

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=211, Percent_Identity=27.4881516587678, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1790244, Length=210, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 24614; Mature: 24482

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKSRDLALKRYAKWLVDEGELSSDPLLGLKPPKGDQKVVNALTEDQLKRLIAACQGKSL
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
MDRRDETIVRLMAETGLRANETLSLQITDVNLDAGIVTIVRGKGGKGRVSPFSVQTATAI
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHH
DRYLRARRAHRLSNTGALWLGGGGKSLGYYGLSKALKQRATAAGIETFHLHMLRHTAATR
HHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
WLRAGGSESGLMSVAGWKNRSMIDRYVGAAAASLAADEARRLNLGDI
HHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKSRDLALKRYAKWLVDEGELSSDPLLGLKPPKGDQKVVNALTEDQLKRLIAACQGKSL
CCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
MDRRDETIVRLMAETGLRANETLSLQITDVNLDAGIVTIVRGKGGKGRVSPFSVQTATAI
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHH
DRYLRARRAHRLSNTGALWLGGGGKSLGYYGLSKALKQRATAAGIETFHLHMLRHTAATR
HHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
WLRAGGSESGLMSVAGWKNRSMIDRYVGAAAASLAADEARRLNLGDI
HHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]