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The map label for this gene is pimC [H]

Identifier: 41408143

GI number: 41408143

Start: 2253311

End: 2254456

Strand: Direct

Name: pimC [H]

Synonym: MAP2045

Alternate gene names: 41408143

Gene position: 2253311-2254456 (Clockwise)

Preceding gene: 41408142

Following gene: 41408144

Centisome position: 46.65

GC content: 72.25

Gene sequence:

>1146_bases
ATGCGTGTCGTACAGGTCGCCAATTTCTATGGCCCTCGCTCCGGCGGCCTTCGCACCGCGGTCGACCGACTGGGCGCCGA
ATACTGCGCCCACGGCCACGAGGTCTTCCTGATCGTTCCGGGGCAGCGCACCGAGCGTGCCCGGCTGTACACCGGCGTGG
TGCGAATCACCTTGCCCGCCCGACTGATTCCCTTCACCGGCGGCTACCGCGCGGTGCTGCCGGGCCCGGTCAAGGCGCTG
CTGGAAGCGTTGCGGCCCGACGCACTGGAGGTGTCCGACCGGCTCACCCTGCGATCGCTGGGCCGCTGGGGCCGCGACCA
CGGCGTCACGACGGTGATGATCTCTCACGAGCGGCTGGATCGCCTTGTGGGGCAGGTACTTCCGCGTCGGGCAGCGCAGA
AGTTCGCCGACTTGGCCAACGCCCGCACCGCCGCCGACTACGACACCGTGGTGTGCACCACGGGCTTTGCGCGTGAGGAA
TTCGACCGCATCGGCGCCGGCAACACCGTCACCGTCCCGCTGGGGGTGGACCTGCAGACGTTTCATCCGCGGCACCACTC
GCAGCTGGTGCGCCGCCGCTGGGCGGCGCCGACCCAGCTGCTGCTGGTCCATTGCGGCCGGCTGTCGGTGGAAAAGCGCG
TCGACCGCAGCATCGACGCGCTCGGCGAGCTGTGCCACGCCGGTGTCGACGCGCGGCTGGTGGTGGTGGGCGAGGGCCCG
CTGCGGGCCAGGCTGCAGCGGCAGGCCGCCCGGCTCCCGGTCGACTTCACCGGTTTCGTCTCCGATCGCACCACCGTGGC
CCAGCTGCTCGCCTCGGCCGATGTGACGCTGGCCCCGGGACCGCACGAGACGTTCGGGCTGGCCGCGCTGGAGTCGCTGG
CGTGCGGCACGCCGGCCGTGGTCTCCCGCACCTCGGCGCTGACCGAGATCGTCACCCCGGACAGCGGCGCGTCGGCCGCC
AACGACCCGGCCGCCATCGCGCGAGCGGTCAGCGCCATCGTCAGCCGGCCCGAGCGGCAGCGCCGCATTTCCGCGCAGCG
CCGCGCCGAGGACTTCACCTGGCACCGGGCCGCCGCCGGCATGCTGGCGTCGTTGCGGGCACCGGTTTTCGACGATCCGG
GCGGGGACTCCGAACAAACCGCCTGA

Upstream 100 bases:

>100_bases
ACCGCCGAGCAGCACCCCGCCAGGCGAAGTTCATCTAGTGTTCAGGCCCGCGTCGGGCCAGCATTGAGGAGTGCACACGC
GCGCCGCGTGTCCTCACGGT

Downstream 100 bases:

>100_bases
CTGGCGCGGCGCGTCCGCGTCGCTCGCCGTGTGTGCGCCACCCGTTGCTCCTGTCGACGGCCCCCGTCACCCGGGCCTTT
TCGCCGCGCCGCTCGGGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MRVVQVANFYGPRSGGLRTAVDRLGAEYCAHGHEVFLIVPGQRTERARLYTGVVRITLPARLIPFTGGYRAVLPGPVKAL
LEALRPDALEVSDRLTLRSLGRWGRDHGVTTVMISHERLDRLVGQVLPRRAAQKFADLANARTAADYDTVVCTTGFAREE
FDRIGAGNTVTVPLGVDLQTFHPRHHSQLVRRRWAAPTQLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGP
LRARLQRQAARLPVDFTGFVSDRTTVAQLLASADVTLAPGPHETFGLAALESLACGTPAVVSRTSALTEIVTPDSGASAA
NDPAAIARAVSAIVSRPERQRRISAQRRAEDFTWHRAAAGMLASLRAPVFDDPGGDSEQTA

Sequences:

>Translated_381_residues
MRVVQVANFYGPRSGGLRTAVDRLGAEYCAHGHEVFLIVPGQRTERARLYTGVVRITLPARLIPFTGGYRAVLPGPVKAL
LEALRPDALEVSDRLTLRSLGRWGRDHGVTTVMISHERLDRLVGQVLPRRAAQKFADLANARTAADYDTVVCTTGFAREE
FDRIGAGNTVTVPLGVDLQTFHPRHHSQLVRRRWAAPTQLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGP
LRARLQRQAARLPVDFTGFVSDRTTVAQLLASADVTLAPGPHETFGLAALESLACGTPAVVSRTSALTEIVTPDSGASAA
NDPAAIARAVSAIVSRPERQRRISAQRRAEDFTWHRAAAGMLASLRAPVFDDPGGDSEQTA
>Mature_381_residues
MRVVQVANFYGPRSGGLRTAVDRLGAEYCAHGHEVFLIVPGQRTERARLYTGVVRITLPARLIPFTGGYRAVLPGPVKAL
LEALRPDALEVSDRLTLRSLGRWGRDHGVTTVMISHERLDRLVGQVLPRRAAQKFADLANARTAADYDTVVCTTGFAREE
FDRIGAGNTVTVPLGVDLQTFHPRHHSQLVRRRWAAPTQLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGP
LRARLQRQAARLPVDFTGFVSDRTTVAQLLASADVTLAPGPHETFGLAALESLACGTPAVVSRTSALTEIVTPDSGASAA
NDPAAIARAVSAIVSRPERQRRISAQRRAEDFTWHRAAAGMLASLRAPVFDDPGGDSEQTA

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of the alpha-1,6-linked mannose residue of the triacyl phosphatidylinositol dimannoside (Ac3PIM2) to generate triacyl phosphatidylinositol trimannoside (Ac3PIM3) [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 41152; Mature: 41152

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVQVANFYGPRSGGLRTAVDRLGAEYCAHGHEVFLIVPGQRTERARLYTGVVRITLPA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHEEEEEEECC
RLIPFTGGYRAVLPGPVKALLEALRPDALEVSDRLTLRSLGRWGRDHGVTTVMISHERLD
EEEECCCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHH
RLVGQVLPRRAAQKFADLANARTAADYDTVVCTTGFAREEFDRIGAGNTVTVPLGVDLQT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCHHH
FHPRHHSQLVRRRWAAPTQLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGP
CCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCH
LRARLQRQAARLPVDFTGFVSDRTTVAQLLASADVTLAPGPHETFGLAALESLACGTPAV
HHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCHHH
VSRTSALTEIVTPDSGASAANDPAAIARAVSAIVSRPERQRRISAQRRAEDFTWHRAAAG
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MLASLRAPVFDDPGGDSEQTA
HHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVVQVANFYGPRSGGLRTAVDRLGAEYCAHGHEVFLIVPGQRTERARLYTGVVRITLPA
CCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHEEEEEEECC
RLIPFTGGYRAVLPGPVKALLEALRPDALEVSDRLTLRSLGRWGRDHGVTTVMISHERLD
EEEECCCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHHH
RLVGQVLPRRAAQKFADLANARTAADYDTVVCTTGFAREEFDRIGAGNTVTVPLGVDLQT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCHHH
FHPRHHSQLVRRRWAAPTQLLLVHCGRLSVEKRVDRSIDALGELCHAGVDARLVVVGEGP
CCCHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCH
LRARLQRQAARLPVDFTGFVSDRTTVAQLLASADVTLAPGPHETFGLAALESLACGTPAV
HHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCHHH
VSRTSALTEIVTPDSGASAANDPAAIARAVSAIVSRPERQRRISAQRRAEDFTWHRAAAG
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MLASLRAPVFDDPGGDSEQTA
HHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10531227 [H]