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The map label for this gene is yjcE

Identifier: 41408141

GI number: 41408141

Start: 2250366

End: 2251976

Strand: Direct

Name: yjcE

Synonym: MAP2043

Alternate gene names: 41408141

Gene position: 2250366-2251976 (Clockwise)

Preceding gene: 41408139

Following gene: 41408142

Centisome position: 46.59

GC content: 70.27

Gene sequence:

>1611_bases
GTGTTCGGCCTCGTCCTGATCGTCGCCCTGGTGTCCACCGTCATCGTGGGCACGGTCATCGGCCGTCGCTACCGGGTGGG
CCCGCCGGTGCTGCTCATCGTGCTCGGCGTGCTGCTGGGTCTGGTCCCGCAGTTCGGGCACGTGCGGATCGACGGCGAGA
TCGTGTTGCTGCTGTTCCTTCCCGCCATCCTGTACTGGGAAGGCCTGAACATCAGCTTCCGCGAGATCCGGGCCAACGCA
CGCATCATCGTGTTCCTCAGCGTCGCGCTGGTCATCGCCACCGCGGTGGCGGTGTCGTGGACGGCGCGGGCGCTGGGCAT
GGATCCGCATGCGGCCGGAGTGCTGGGCGCGGTGCTCTCCCCCACCGACGCGGCCGCGGTGGCCGGGCTGGCCAAGAAGC
TGCCCCGCCGCTCGCTGACGGTGTTGAAGGCCGAGAGTCTGATCAACGACGGCACCGCGCTGGTGTTGTTCGCGGTCAGC
GTGCACGTCGCGATCGGCGCGCCGGCGATCAGCCCACCGGAGGTCACACTCCGGTTCATCGGCTCGTACCTGGGTGGGAT
CGCCGCGGGCCTGCTGGTCGGCGGCGCAGTGACGCTGGTGCGCAAGCGAATTGACGCGCCCCAGGAAGAGGGAGCGCTGA
GTTTGGTGACGCCCTTCGCGGCGTTCCTGCTGGCGCAATCGGTCGAGTGCAGCGGGGTGGTCGCGGTGGTGGTGTCGGCC
CTGGTGCTGGCCTACTCCGGGCCGGTGGTGATCCGGGCCCGCTCCCGGCTGCAGTCCTACGCCTTCTGGGACATCGCGAC
GTTCCTGCTCAACGGCTCGTTGTGGGTGTTCGTCGGTGTCCAGATCCCCGGTGCGCTGCGCGGCATCGCGGGCGTCGACG
GCGGTGTGCGGCACGCCCTGTTCGTCGCGCTGGTGATCACCGGGGTGGTGATCGTGTCGCGCATCTTCTGGGGCGAATTC
ACCACCATGCTGATCCGGCTGATCGACCGCCGGGCGGTGCAACGCGAACGCCGGGTCGGCTGGCGGCAGCGCTTCGTCAC
CGCCTGGGCCGGATTCCGCGGGGCGGTGTCGCTGGCCGCGGCGGTGGCCGTGCCGATGACCACGCTGAGCGGCGCGCCGT
TCCCGGACCACAGCCTGCTGATCTTCATCGTCACCGTTGTCATCCTGGTGACCGTGCTGGTGCAGGGCAGCACGCTGCCC
GCTGTGGTGCGCTGGGCGCGGCTGCCGGCGGACGTCGCGCACGCCGAGGAGCTGCAGCTGGCCCGCACCCGTGCCGCCCG
CGCCGCCCTAGCCGCCCTACCCGCGGTCGCCGACGAGGTCGGCGTCAGCGACGAGCTGCGCCGGCGGCTGCACAAGGAAT
ACGAAGAGAAGGCCGCGCTGGTGCTGGCCACCGAGAACGGTTCGCCGGACAACCGGATCCTCAAGACCCGGGAGAAGGTC
CGGCAGGTGCGGCTGGGGGTGCTCGAGCACAAGCGCCGCGAGGTCACCGCGCTGCGCAATCAGAACCGGATCGACGACAC
GGTGCTGCGGGAGCTGCAAAACGAGATGGATCTCGAGGAGGTGCAGCTGCTGGCCGCCGCGGCCGACGAGGACGACGGCG
ACACGGAATAG

Upstream 100 bases:

>100_bases
ATCGGCCGTGACCCAGACCGAAGATAGGCGAAGAAGCGCCGGCGCATGACGTCGTGCGGCCCCCGCGGCCACCGTCCGTC
GCGTCCGGCAGGATGGGCTG

Downstream 100 bases:

>100_bases
GGCCCGTCGGTGGCCGACCGTACAGTCGGCCTCATGCTGCACACCGTCGCGGTCCGGGGCTACCGCTCGCTGCGCGAGGT
GGTTCTGCCGCTGGGCCGGC

Product: YjcE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFLPAILYWEGLNISFREIRANA
RIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLSPTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVS
VHVAIGAPAISPPEVTLRFIGSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA
LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHALFVALVITGVVIVSRIFWGEF
TTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAAAVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLP
AVVRWARLPADVAHAEELQLARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV
RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLLAAAADEDDGDTE

Sequences:

>Translated_536_residues
MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFLPAILYWEGLNISFREIRANA
RIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLSPTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVS
VHVAIGAPAISPPEVTLRFIGSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA
LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHALFVALVITGVVIVSRIFWGEF
TTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAAAVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLP
AVVRWARLPADVAHAEELQLARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV
RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLLAAAADEDDGDTE
>Mature_536_residues
MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFLPAILYWEGLNISFREIRANA
RIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLSPTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVS
VHVAIGAPAISPPEVTLRFIGSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA
LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHALFVALVITGVVIVSRIFWGEF
TTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAAAVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLP
AVVRWARLPADVAHAEELQLARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV
RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLLAAAADEDDGDTE

Specific function: Unknown

COG id: COG0025

COG function: function code P; NhaP-type Na+/H+ and K+/H+ antiporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family [H]

Homologues:

Organism=Homo sapiens, GI27734935, Length=398, Percent_Identity=21.608040201005, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1790501, Length=560, Percent_Identity=29.4642857142857, Blast_Score=166, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71987545, Length=409, Percent_Identity=22.4938875305623, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71987559, Length=409, Percent_Identity=22.4938875305623, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364513, Length=390, Percent_Identity=22.0512820512821, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221473222, Length=390, Percent_Identity=22.0512820512821, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221473215, Length=390, Percent_Identity=22.0512820512821, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221473212, Length=413, Percent_Identity=21.5496368038741, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR018422
- InterPro:   IPR004705 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 57436; Mature: 57436

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHH
PAILYWEGLNISFREIRANARIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLS
HHHHHHCCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
PTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVSVHVAIGAPAISPPEVTLRFI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHAL
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHCCCCHHHHHH
FVALVITGVVIVSRIFWGEFTTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLPAVVRWARLPADVAHAEELQL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
ARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHH
RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLLAAAADEDDGDTE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFL
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHHH
PAILYWEGLNISFREIRANARIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLS
HHHHHHCCCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCC
PTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVSVHVAIGAPAISPPEVTLRFI
CCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
GSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHAL
HHHHHCCCEEEEEHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHCCCCHHHHHH
FVALVITGVVIVSRIFWGEFTTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLPAVVRWARLPADVAHAEELQL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHH
ARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHH
RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLLAAAADEDDGDTE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]