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The map label for this gene is asnB_2

Identifier: 41408039

GI number: 41408039

Start: 2142152

End: 2144083

Strand: Direct

Name: asnB_2

Synonym: MAP1941

Alternate gene names: 41408039

Gene position: 2142152-2144083 (Clockwise)

Preceding gene: 41408033

Following gene: 41408041

Centisome position: 44.35

GC content: 69.57

Gene sequence:

>1932_bases
GTGTGTGGTCTGCTGGCGTTCGTCGCCGCCCGAGCCGGTGCCGTCGGCGCCGACGACGCGATCGCGCGCGCCTCGCACCT
GATGCGCCACCGCGGGCCCGACGAGCCGGGCACCTGGGCGGGCGCCGACGGCTCCGTCGTGTTCGGCTTCAACCGGCTGT
CGATCATCGACATCGCCCATTCGCACCAGCCGCTGCGCTGGGGCCCGCCCGAGACGCCGGACCGCTACGAGCTGGTGTTC
AACGGCGAGATCTACAACTACCTGGAGCTGCGCGACGAGCTGGCCGCCCGCCACGGCGCGGTGTTCGCCACCGACGGCGA
CGGCGAGGCCATCGTCGCCGGCTTCCACCACTGGGGCACCGATGTGTTGACCCGGCTGCGCGGCATGTTCGCGTTTGCGT
TGTGGGACACCGTCACTCGCGAATTGTTCTGTGCCCGTGACCCTTTCGGCATCAAACCGCTGTTCGTGGCGACCGGCACC
GGCGGCACCGCGGTGGCCAGCGAGAAGAAGTGCCTGCTGGAGCTGGCCGAGTTGATCGGGTTCGACACCGCGATCGATGA
GCGCGCGGTGCAGCACTACACCGTCCTGCAGTACGTGCCGGAGCCCGAGACGCTGCACCGCGGGGTGCGACGGCTGGAAT
CGGGCTGTTATGCCCGGATCCGGCCCGGCGCGGCGCCCGACGTCACCCGCTACTTCGTGCCCCGGTTCGCCGCCGTGCCC
ATCACCCGCGACACCGAACAGGCCCGCTACGACGAGATCACCGCGGTGCTCGAAGATTCGGTGGCCAAACACATGCGCGC
CGACGTCACCGTCGGGGCGTTTCTGTCCGGCGGCATCGACTCGACCGCCATCGCGGCGCTGGCCATCCGGCACAACCCGC
GGCTGATCACCTTCACCACCGGTTTCGAGCGCGAGGGATTCTCCGAGATCGACGTCGCGGTGGCCTCGGCGGAGGCGATC
GGCGCCCGGCACATCGCCAAGGTGGTGCACCCCGACGAGTTCGTCGCCGCCCTGCCCGAGATCGTCTGGTACCTCGACGA
GCCGGTCGCCGACCCGGCGCTGGTGCCGTTGTTCTTTGTCGCCCGGGAGGCCCGCAAGCACGTCAAGGTGGTGCTCTCCG
GTGAGGGCGCCGACGAGCTGTTCGGCGGCTACACGATCTACCGGGAACCGTTGTCGCTGCGGCCTTTCGACTACCTGCCG
CGGCCGGTGCGGCGCTCGATGGGCAAGGTGTCCAGGCCGCTGCCGGACGGGATGCGCGGCAAGAGCCTGCTGCACCGCGG
GTCGCTGACGCTCGAGGAGCGCTACTACGGCAACGCCCGCAGCTTCTCCGATACACAGCTGCGCGACGTGCTGCCCGGCT
TCCGCGCGGAATGGACGCACACCGACGTCACCGCGGCGCTGTACGCGCAGTCGATCGGCTGGGACCCGGTGGCGCGCATG
CAGCACATCGACCTGTTCACCTGGCTGCGCGGAGACATCCTGGTCAAGGCCGACAAGATGACGATGGCCAACTCGCTGGA
GCTGCGGGTGCCGTTCCTGGATCCCGAGGTGTTCGCCGTGGCGTCCCGATTGCCGGTGGAGGCCAAGATCACCCGCACCA
CCACGAAGTACGCGTTGCGGCGGGCGCTGGAGCCGATCGTTCCCGCGCACGTGCTGCACCGGCCCAAGCTCGGCTTCCCG
GTCCCGATCCGGCATTGGCTGCGCGCCGGCGAGCTGCAGGACTGGGCCTACTCGATGGTGGCGTCGTCTCAGGCCGGTCA
CCTGGTGGACCTGGGCGCCGTGCGCCGGATGCTCGACGAGCACCGCAACGGCGTCAGCGATCACAGCCGCCGGCTGTGGA
CGGTGCTGATCTTCATGCTGTGGCACGCCATCTTCGTCGAGCACAGCGTGGTGCCGCAGATCAGCGAGCCGGTGTACCCG
GTGCAGCTCTGA

Upstream 100 bases:

>100_bases
ATCGAATACTACGCAGCGTAGACCACGCGTCTGAGCCGGGCGACGAAACCCCGGCCCGCCAGTCGGTCCCGGCGTTGGAC
GTGCGGCATACTGGGGCGCC

Downstream 100 bases:

>100_bases
GCGGGCTGGTCAGTACAGCTAGGCCAGCAGCGCGGCGATCTCGGCGGCCGCGTCCTCGCCGTACGCGCCGGCCAGCCGGC
TCTTGGCGACCTCGTGGTCC

Product: AsnB_2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MCGLLAFVAARAGAVGADDAIARASHLMRHRGPDEPGTWAGADGSVVFGFNRLSIIDIAHSHQPLRWGPPETPDRYELVF
NGEIYNYLELRDELAARHGAVFATDGDGEAIVAGFHHWGTDVLTRLRGMFAFALWDTVTRELFCARDPFGIKPLFVATGT
GGTAVASEKKCLLELAELIGFDTAIDERAVQHYTVLQYVPEPETLHRGVRRLESGCYARIRPGAAPDVTRYFVPRFAAVP
ITRDTEQARYDEITAVLEDSVAKHMRADVTVGAFLSGGIDSTAIAALAIRHNPRLITFTTGFEREGFSEIDVAVASAEAI
GARHIAKVVHPDEFVAALPEIVWYLDEPVADPALVPLFFVAREARKHVKVVLSGEGADELFGGYTIYREPLSLRPFDYLP
RPVRRSMGKVSRPLPDGMRGKSLLHRGSLTLEERYYGNARSFSDTQLRDVLPGFRAEWTHTDVTAALYAQSIGWDPVARM
QHIDLFTWLRGDILVKADKMTMANSLELRVPFLDPEVFAVASRLPVEAKITRTTTKYALRRALEPIVPAHVLHRPKLGFP
VPIRHWLRAGELQDWAYSMVASSQAGHLVDLGAVRRMLDEHRNGVSDHSRRLWTVLIFMLWHAIFVEHSVVPQISEPVYP
VQL

Sequences:

>Translated_643_residues
MCGLLAFVAARAGAVGADDAIARASHLMRHRGPDEPGTWAGADGSVVFGFNRLSIIDIAHSHQPLRWGPPETPDRYELVF
NGEIYNYLELRDELAARHGAVFATDGDGEAIVAGFHHWGTDVLTRLRGMFAFALWDTVTRELFCARDPFGIKPLFVATGT
GGTAVASEKKCLLELAELIGFDTAIDERAVQHYTVLQYVPEPETLHRGVRRLESGCYARIRPGAAPDVTRYFVPRFAAVP
ITRDTEQARYDEITAVLEDSVAKHMRADVTVGAFLSGGIDSTAIAALAIRHNPRLITFTTGFEREGFSEIDVAVASAEAI
GARHIAKVVHPDEFVAALPEIVWYLDEPVADPALVPLFFVAREARKHVKVVLSGEGADELFGGYTIYREPLSLRPFDYLP
RPVRRSMGKVSRPLPDGMRGKSLLHRGSLTLEERYYGNARSFSDTQLRDVLPGFRAEWTHTDVTAALYAQSIGWDPVARM
QHIDLFTWLRGDILVKADKMTMANSLELRVPFLDPEVFAVASRLPVEAKITRTTTKYALRRALEPIVPAHVLHRPKLGFP
VPIRHWLRAGELQDWAYSMVASSQAGHLVDLGAVRRMLDEHRNGVSDHSRRLWTVLIFMLWHAIFVEHSVVPQISEPVYP
VQL
>Mature_643_residues
MCGLLAFVAARAGAVGADDAIARASHLMRHRGPDEPGTWAGADGSVVFGFNRLSIIDIAHSHQPLRWGPPETPDRYELVF
NGEIYNYLELRDELAARHGAVFATDGDGEAIVAGFHHWGTDVLTRLRGMFAFALWDTVTRELFCARDPFGIKPLFVATGT
GGTAVASEKKCLLELAELIGFDTAIDERAVQHYTVLQYVPEPETLHRGVRRLESGCYARIRPGAAPDVTRYFVPRFAAVP
ITRDTEQARYDEITAVLEDSVAKHMRADVTVGAFLSGGIDSTAIAALAIRHNPRLITFTTGFEREGFSEIDVAVASAEAI
GARHIAKVVHPDEFVAALPEIVWYLDEPVADPALVPLFFVAREARKHVKVVLSGEGADELFGGYTIYREPLSLRPFDYLP
RPVRRSMGKVSRPLPDGMRGKSLLHRGSLTLEERYYGNARSFSDTQLRDVLPGFRAEWTHTDVTAALYAQSIGWDPVARM
QHIDLFTWLRGDILVKADKMTMANSLELRVPFLDPEVFAVASRLPVEAKITRTTTKYALRRALEPIVPAHVLHRPKLGFP
VPIRHWLRAGELQDWAYSMVASSQAGHLVDLGAVRRMLDEHRNGVSDHSRRLWTVLIFMLWHAIFVEHSVVPQISEPVYP
VQL

Specific function: Asparagine biosynthesis. [C]

COG id: COG0367

COG function: function code E; Asparagine synthase (glutamine-hydrolyzing)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI168229248, Length=409, Percent_Identity=28.1173594132029, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI168229252, Length=409, Percent_Identity=28.1173594132029, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI168229250, Length=409, Percent_Identity=28.1173594132029, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI296010848, Length=377, Percent_Identity=28.6472148541114, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI296010852, Length=303, Percent_Identity=28.0528052805281, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI296010850, Length=303, Percent_Identity=28.0528052805281, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1786889, Length=407, Percent_Identity=28.5012285012285, Blast_Score=147, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71993933, Length=412, Percent_Identity=27.1844660194175, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI25147557, Length=412, Percent_Identity=27.1844660194175, Blast_Score=122, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17560178, Length=425, Percent_Identity=28.2352941176471, Blast_Score=115, Evalue=8e-26,
Organism=Saccharomyces cerevisiae, GI6325403, Length=444, Percent_Identity=27.9279279279279, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6321563, Length=442, Percent_Identity=27.1493212669683, Blast_Score=126, Evalue=9e-30,
Organism=Drosophila melanogaster, GI45553209, Length=384, Percent_Identity=31.5104166666667, Blast_Score=162, Evalue=9e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006426
- InterPro:   IPR001962
- InterPro:   IPR017932
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00733 Asn_synthase [H]

EC number: =6.3.5.4 [H]

Molecular weight: Translated: 71581; Mature: 71581

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGLLAFVAARAGAVGADDAIARASHLMRHRGPDEPGTWAGADGSVVFGFNRLSIIDIAH
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEEEECC
SHQPLRWGPPETPDRYELVFNGEIYNYLELRDELAARHGAVFATDGDGEAIVAGFHHWGT
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEHHHHHH
DVLTRLRGMFAFALWDTVTRELFCARDPFGIKPLFVATGTGGTAVASEKKCLLELAELIG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHC
FDTAIDERAVQHYTVLQYVPEPETLHRGVRRLESGCYARIRPGAAPDVTRYFVPRFAAVP
CCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHCHHEECC
ITRDTEQARYDEITAVLEDSVAKHMRADVTVGAFLSGGIDSTAIAALAIRHNPRLITFTT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCHHHHHHEEEECCCEEEEEEC
GFEREGFSEIDVAVASAEAIGARHIAKVVHPDEFVAALPEIVWYLDEPVADPALVPLFFV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AREARKHVKVVLSGEGADELFGGYTIYREPLSLRPFDYLPRPVRRSMGKVSRPLPDGMRG
HHHHHCCEEEEEECCCHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
KSLLHRGSLTLEERYYGNARSFSDTQLRDVLPGFRAEWTHTDVTAALYAQSIGWDPVARM
HHHHHCCCCEEHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
QHIDLFTWLRGDILVKADKMTMANSLELRVPFLDPEVFAVASRLPVEAKITRTTTKYALR
HHHHHHHHHCCCEEEEECCEEECCCCEEEEECCCCHHHHHHHCCCCEEEEEHHHHHHHHH
RALEPIVPAHVLHRPKLGFPVPIRHWLRAGELQDWAYSMVASSQAGHLVDLGAVRRMLDE
HHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
HRNGVSDHSRRLWTVLIFMLWHAIFVEHSVVPQISEPVYPVQL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MCGLLAFVAARAGAVGADDAIARASHLMRHRGPDEPGTWAGADGSVVFGFNRLSIIDIAH
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCEEEEEECC
SHQPLRWGPPETPDRYELVFNGEIYNYLELRDELAARHGAVFATDGDGEAIVAGFHHWGT
CCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEEEHHHHHH
DVLTRLRGMFAFALWDTVTRELFCARDPFGIKPLFVATGTGGTAVASEKKCLLELAELIG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHC
FDTAIDERAVQHYTVLQYVPEPETLHRGVRRLESGCYARIRPGAAPDVTRYFVPRFAAVP
CCHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHCHHEECC
ITRDTEQARYDEITAVLEDSVAKHMRADVTVGAFLSGGIDSTAIAALAIRHNPRLITFTT
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCHHHHHHEEEECCCEEEEEEC
GFEREGFSEIDVAVASAEAIGARHIAKVVHPDEFVAALPEIVWYLDEPVADPALVPLFFV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
AREARKHVKVVLSGEGADELFGGYTIYREPLSLRPFDYLPRPVRRSMGKVSRPLPDGMRG
HHHHHCCEEEEEECCCHHHHHCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
KSLLHRGSLTLEERYYGNARSFSDTQLRDVLPGFRAEWTHTDVTAALYAQSIGWDPVARM
HHHHHCCCCEEHHHHCCCCCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHH
QHIDLFTWLRGDILVKADKMTMANSLELRVPFLDPEVFAVASRLPVEAKITRTTTKYALR
HHHHHHHHHCCCEEEEECCEEECCCCEEEEECCCCHHHHHHHCCCCEEEEEHHHHHHHHH
RALEPIVPAHVLHRPKLGFPVPIRHWLRAGELQDWAYSMVASSQAGHLVDLGAVRRMLDE
HHHHHHCCHHHHCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCEEHHHHHHHHHHH
HRNGVSDHSRRLWTVLIFMLWHAIFVEHSVVPQISEPVYPVQL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]