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The map label for this gene is sigC [H]

Identifier: 41407912

GI number: 41407912

Start: 1991733

End: 1993112

Strand: Direct

Name: sigC [H]

Synonym: MAP1814

Alternate gene names: 41407912

Gene position: 1991733-1993112 (Clockwise)

Preceding gene: 41407910

Following gene: 41407918

Centisome position: 41.24

GC content: 72.03

Gene sequence:

>1380_bases
ATGCGCAACGATGCAGGGATGCGGTGTGACGTTGCCCGGGAGGCGCTGTCGGCTCGGCTGGACGGTGAGCGTCCTCAGGT
GCTCGCGCAGCAGGTCGATGCCCACCTCGAGGCGTGCCGGGGCTGCCGCTCCTGGCTGATCGGGGCGGCGGTGCAGACCC
GTCGGCTGGCCTCGGTGACGCCGGGCGAGGGACCCGACCTGGTGGACAAGATCATGGCCAGCATCGGCGAGCAGCCGACC
GGGCGCCCGGCCTGGATGCGCTGGTTGCGGTCGCACTACCGCCGCTGGGGGCTGATCGGAGTCGGCCTGTTCCAGGTGGC
GATCGCCGCCGCCCAGATCAGCGGGATCGATTTCGGCATGGTCGCCGGCCACATGCACGGCGCCATGTCCGGCGAGCACC
TGATGCACGAGTCCACGGCGTGGTTGCTGGCGCTCGGGCTGGCGATGATCGCCGCCGGCGTCTGGCCCGCCTCGGCGTCG
GGGGTGGCGGCGATCACCGGCGTGTATTCGGTTGCGCTGCTGGGCTATGTCATCGTCGACGCCTTCGACGGGGAGGTGAC
CGCCACCCGCATCGCCAGCCACATGCCGCTGCTGCTCGGCCTGGCCTTCGCGTTGCTGGTGGCGCGGGAACGGGTGGGAT
CGCGCCGGCCCGGCTCCTCCGACGCGACGGCGGACGCCGGCTTTGCGGCCTGGGCCGCTGACGCTCCCGCGGGCCGGCGG
CGCGGACACCTGCGGCCCATCAATCGCGCGGCCCCCGACCCCACCGCATCGTCTACGACGACCCGTCGTAGGATCGGAAA
ACCCGCGCAATTAAGGTGGTTGGGCATGATCGCGCCGAGCGACGACGAGGCGGTAACCGAGCTCGCGTTGTCCGCCGCGC
GCGGGAACGCCCGGGCGCTCGAGGCGTTCATCAAGGCCACCCAGCAAGACGTGTGGCGGTTCGTCGCGTATCTGTGCGAT
GCGGGCAGTGCCGACGATCTGCCCCAGGAGACGTTCCTGCGCGCGATCGGCGCCATCGAGCGGTTCTCCGGACGCTCGAG
TGCCCGGACCTGGCTGCTGTCCATCGCGCGCCGCGTCGTGGCCGACCACATCCGTCACCTGCAGTCGCGGCCGCGCGCCG
CGGTGGGCGCCGATCCCGAACACGTGCTGCGCACCGACCGCCACGCCCGCGGATTCGAGGATCTGGTCGAGGTGACGACG
ATGATCGCCAGCCTCAATCCCGAACAGCGCGAAGCGCTGTTGCTCACCCAGTTGCTCGGGCTGCCCTACGCCGACGCCGC
CGCGGTGTGCGGCTGCCCGGTGGGCACCATCCGATCGCGGGTGGCCCGGGCCCGCGACGCGCTGCTGGCCGACGGCGAGC
GCAGCGACCTGACCGGCTAG

Upstream 100 bases:

>100_bases
TGGCGAGCTTTCCCCCACAGGTCGGTCACCGGGACCGTTTGGTTCCACGCAAATTCGCGCGGCGCCCCAACTCGCGGGAG
TCTTTGCGCGCAGACCCGCC

Downstream 100 bases:

>100_bases
TCCTTGATCGCCAGCGCCGCAACCCATTCGGCGGCCTCGGCCACACTGCCGACCGCCGACACGCCGGCCGGCAGCGCCGG
CCTTGCCACCATCACCACCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MRNDAGMRCDVAREALSARLDGERPQVLAQQVDAHLEACRGCRSWLIGAAVQTRRLASVTPGEGPDLVDKIMASIGEQPT
GRPAWMRWLRSHYRRWGLIGVGLFQVAIAAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPASAS
GVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVARERVGSRRPGSSDATADAGFAAWAADAPAGRR
RGHLRPINRAAPDPTASSTTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARALEAFIKATQQDVWRFVAYLCD
AGSADDLPQETFLRAIGAIERFSGRSSARTWLLSIARRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLVEVTT
MIASLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADGERSDLTG

Sequences:

>Translated_459_residues
MRNDAGMRCDVAREALSARLDGERPQVLAQQVDAHLEACRGCRSWLIGAAVQTRRLASVTPGEGPDLVDKIMASIGEQPT
GRPAWMRWLRSHYRRWGLIGVGLFQVAIAAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPASAS
GVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVARERVGSRRPGSSDATADAGFAAWAADAPAGRR
RGHLRPINRAAPDPTASSTTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARALEAFIKATQQDVWRFVAYLCD
AGSADDLPQETFLRAIGAIERFSGRSSARTWLLSIARRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLVEVTT
MIASLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADGERSDLTG
>Mature_459_residues
MRNDAGMRCDVAREALSARLDGERPQVLAQQVDAHLEACRGCRSWLIGAAVQTRRLASVTPGEGPDLVDKIMASIGEQPT
GRPAWMRWLRSHYRRWGLIGVGLFQVAIAAAQISGIDFGMVAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPASAS
GVAAITGVYSVALLGYVIVDAFDGEVTATRIASHMPLLLGLAFALLVARERVGSRRPGSSDATADAGFAAWAADAPAGRR
RGHLRPINRAAPDPTASSTTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARALEAFIKATQQDVWRFVAYLCD
AGSADDLPQETFLRAIGAIERFSGRSSARTWLLSIARRVVADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLVEVTT
MIASLNPEQREALLLTQLLGLPYADAAAVCGCPVGTIRSRVARARDALLADGERSDLTG

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=173, Percent_Identity=30.0578034682081, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 49142; Mature: 49142

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNDAGMRCDVAREALSARLDGERPQVLAQQVDAHLEACRGCRSWLIGAAVQTRRLASVT
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGEGPDLVDKIMASIGEQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAIAAAQISGIDFGM
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHH
VAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPASASGVAAITGVYSVALLGYVIVD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFDGEVTATRIASHMPLLLGLAFALLVARERVGSRRPGSSDATADAGFAAWAADAPAGRR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCC
RGHLRPINRAAPDPTASSTTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARAL
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHH
EAFIKATQQDVWRFVAYLCDAGSADDLPQETFLRAIGAIERFSGRSSARTWLLSIARRVV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLVEVTTMIASLNPEQREALLLTQLLG
HHHHHHHHHCCCCCCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
LPYADAAAVCGCPVGTIRSRVARARDALLADGERSDLTG
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRNDAGMRCDVAREALSARLDGERPQVLAQQVDAHLEACRGCRSWLIGAAVQTRRLASVT
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PGEGPDLVDKIMASIGEQPTGRPAWMRWLRSHYRRWGLIGVGLFQVAIAAAQISGIDFGM
CCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHH
VAGHMHGAMSGEHLMHESTAWLLALGLAMIAAGVWPASASGVAAITGVYSVALLGYVIVD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
AFDGEVTATRIASHMPLLLGLAFALLVARERVGSRRPGSSDATADAGFAAWAADAPAGRR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCC
RGHLRPINRAAPDPTASSTTTRRRIGKPAQLRWLGMIAPSDDEAVTELALSAARGNARAL
CCCCCCCCCCCCCCCCCCHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCCHHHH
EAFIKATQQDVWRFVAYLCDAGSADDLPQETFLRAIGAIERFSGRSSARTWLLSIARRVV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
ADHIRHLQSRPRAAVGADPEHVLRTDRHARGFEDLVEVTTMIASLNPEQREALLLTQLLG
HHHHHHHHHCCCCCCCCCHHHHHHCCHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
LPYADAAAVCGCPVGTIRSRVARARDALLADGERSDLTG
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]