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The map label for this gene is gltC [H]

Identifier: 41407732

GI number: 41407732

Start: 1789023

End: 1789940

Strand: Direct

Name: gltC [H]

Synonym: MAP1634

Alternate gene names: 41407732

Gene position: 1789023-1789940 (Clockwise)

Preceding gene: 41407726

Following gene: 41407740

Centisome position: 37.04

GC content: 62.64

Gene sequence:

>918_bases
ATGGATCTTCATCAGCTGGAGTGCTTTATCGCGGTCGCCGAGGAAGGCACCTTCACCGCCGCGGCACAGCGGATACATCT
GGCGCAATCTGGTGTTAGTGCACACATTAAGGCGCTCGAACGCGAAATCGGGCAGCAGCTATTCGAACGGCGGCCACGCA
CGGTACGGCTTACCGCGGCTGGAAACGCGCTTCTGCCATACGCCCGCGCAGCACTCGATGCGCTGGCCGCAGGTCGCGCC
TCGATCGACGGACTCACCGGTCTACTACATGGTCGCCTTGCCATCGGCACCATCACCTCGATCTCACCGCGCAGCATCGA
CCTCCCCGAGCTTCTAGCAGCGTTTCACCATGAGCACCCGGGGGTAGACCTGTCGCTGGTTGAGGACACTGCAGCGATGC
TCAATCGCCACATATCCAATGGCGCTTTAGACGTAGCTTTCACCAGCCTGACGGATGAGGCAGTAGCCGGCGTGCGGATG
CGCGAGTTGCATCGGGAGCCGGTGATCGCGATCTTTCTACCGTCCGATCCGTTATCTCCTTGCCGGAAGCTCACATTGGC
CGACGTGGCGGATAGACCGCTCATCACGCTCCCGGAGGGATCAGGCTTGCGCTGGCAACTCAACCGCGCGCTGCGGCGGG
CCGGCGTTCAAGCCCACATCGCCTTCGAAGCCGGCGATCCCGACGTACTCGTTGCGCTCGTTGCGAAGGGGCTGGGCGTG
GGTCTCGTTCCTCAATCAGCCCTCGCGCAAAGCGATCACGTAATAGGATTGCCAGTCAGCGATCATCCGCCCGGGCGCCT
AGGCATCATCTGGCCAGAAGGGCAAGCCGCCAGCCCAGCGGCTCGTGCCTTCGTTGAACACGCCACCACGGCGACAACTA
AACTTCGGCGACCGGCCGAGCTACGCCAGGATCGCTGA

Upstream 100 bases:

>100_bases
GCGGAGCGACCGCAGTGGAGCGCGCCCGCGATTGCGGCTAGTCGGCTTACTAGATGCCCTGCGCGACGAGACGATGCTCT
GTAATAGATTTTCGGTCAGC

Downstream 100 bases:

>100_bases
GTTCTTGCCGAAGCCGGTGGTCCTCGCCGACTTCATTCCCTGCCAGCGCTTTGCCTGCGGGGCATTGATACCGAACTGAT
CGAGAACACGGACCACCACG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDLHQLECFIAVAEEGTFTAAAQRIHLAQSGVSAHIKALEREIGQQLFERRPRTVRLTAAGNALLPYARAALDALAAGRA
SIDGLTGLLHGRLAIGTITSISPRSIDLPELLAAFHHEHPGVDLSLVEDTAAMLNRHISNGALDVAFTSLTDEAVAGVRM
RELHREPVIAIFLPSDPLSPCRKLTLADVADRPLITLPEGSGLRWQLNRALRRAGVQAHIAFEAGDPDVLVALVAKGLGV
GLVPQSALAQSDHVIGLPVSDHPPGRLGIIWPEGQAASPAARAFVEHATTATTKLRRPAELRQDR

Sequences:

>Translated_305_residues
MDLHQLECFIAVAEEGTFTAAAQRIHLAQSGVSAHIKALEREIGQQLFERRPRTVRLTAAGNALLPYARAALDALAAGRA
SIDGLTGLLHGRLAIGTITSISPRSIDLPELLAAFHHEHPGVDLSLVEDTAAMLNRHISNGALDVAFTSLTDEAVAGVRM
RELHREPVIAIFLPSDPLSPCRKLTLADVADRPLITLPEGSGLRWQLNRALRRAGVQAHIAFEAGDPDVLVALVAKGLGV
GLVPQSALAQSDHVIGLPVSDHPPGRLGIIWPEGQAASPAARAFVEHATTATTKLRRPAELRQDR
>Mature_305_residues
MDLHQLECFIAVAEEGTFTAAAQRIHLAQSGVSAHIKALEREIGQQLFERRPRTVRLTAAGNALLPYARAALDALAAGRA
SIDGLTGLLHGRLAIGTITSISPRSIDLPELLAAFHHEHPGVDLSLVEDTAAMLNRHISNGALDVAFTSLTDEAVAGVRM
RELHREPVIAIFLPSDPLSPCRKLTLADVADRPLITLPEGSGLRWQLNRALRRAGVQAHIAFEAGDPDVLVALVAKGLGV
GLVPQSALAQSDHVIGLPVSDHPPGRLGIIWPEGQAASPAARAFVEHATTATTKLRRPAELRQDR

Specific function: Positive regulator of glutamate biosynthesis (gltAB genes). Negatively regulates its own expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=298, Percent_Identity=30.5369127516779, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788296, Length=250, Percent_Identity=34.4, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790399, Length=278, Percent_Identity=29.136690647482, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1788297, Length=247, Percent_Identity=29.9595141700405, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI2367136, Length=282, Percent_Identity=29.7872340425532, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI157672245, Length=252, Percent_Identity=28.968253968254, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790208, Length=296, Percent_Identity=29.3918918918919, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787530, Length=250, Percent_Identity=26.8, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788748, Length=258, Percent_Identity=31.3953488372093, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787601, Length=270, Percent_Identity=27.4074074074074, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI145693105, Length=298, Percent_Identity=24.1610738255034, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87081904, Length=278, Percent_Identity=25.8992805755396, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788887, Length=293, Percent_Identity=30.7167235494881, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=26, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI87082132, Length=310, Percent_Identity=27.0967741935484, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787128, Length=310, Percent_Identity=25.1612903225806, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787949, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994962, Length=101, Percent_Identity=36.6336633663366, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787589, Length=264, Percent_Identity=26.8939393939394, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788481, Length=248, Percent_Identity=25.8064516129032, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693193, Length=131, Percent_Identity=36.6412213740458, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32546; Mature: 32546

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLHQLECFIAVAEEGTFTAAAQRIHLAQSGVSAHIKALEREIGQQLFERRPRTVRLTAA
CCCHHEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GNALLPYARAALDALAAGRASIDGLTGLLHGRLAIGTITSISPRSIDLPELLAAFHHEHP
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
GVDLSLVEDTAAMLNRHISNGALDVAFTSLTDEAVAGVRMRELHREPVIAIFLPSDPLSP
CCEEEHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
CRKLTLADVADRPLITLPEGSGLRWQLNRALRRAGVQAHIAFEAGDPDVLVALVAKGLGV
HHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCC
GLVPQSALAQSDHVIGLPVSDHPPGRLGIIWPEGQAASPAARAFVEHATTATTKLRRPAE
CCCCHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHH
LRQDR
HHCCC
>Mature Secondary Structure
MDLHQLECFIAVAEEGTFTAAAQRIHLAQSGVSAHIKALEREIGQQLFERRPRTVRLTAA
CCCHHEEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEC
GNALLPYARAALDALAAGRASIDGLTGLLHGRLAIGTITSISPRSIDLPELLAAFHHEHP
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCC
GVDLSLVEDTAAMLNRHISNGALDVAFTSLTDEAVAGVRMRELHREPVIAIFLPSDPLSP
CCEEEHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCH
CRKLTLADVADRPLITLPEGSGLRWQLNRALRRAGVQAHIAFEAGDPDVLVALVAKGLGV
HHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCCC
GLVPQSALAQSDHVIGLPVSDHPPGRLGIIWPEGQAASPAARAFVEHATTATTKLRRPAE
CCCCHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCHH
LRQDR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548995; 9384377 [H]