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The map label for this gene is fadB1 [H]

Identifier: 41407691

GI number: 41407691

Start: 1749858

End: 1750607

Strand: Direct

Name: fadB1 [H]

Synonym: MAP1593

Alternate gene names: 41407691

Gene position: 1749858-1750607 (Clockwise)

Preceding gene: 41407690

Following gene: 41407693

Centisome position: 36.23

GC content: 69.6

Gene sequence:

>750_bases
GTGACGCTGCAGATCGACGACGACAAGCGGGTACGCACCCTCACGCTGAACCGCCCGGAGGCGCTGAACGCGTTCAACGA
AGCCCTCTACGACGCCACCGCCGAGGCGTTGCTGGCCGCGGCCGAGGATCCCGAGGTGGCGGTCGTGCTGCTGACCGGGG
CGGGGCGCGGGTTCAGCGCCGGCACCGACCTGGCCGAGATGCAGGCCCGCATCACCGACCCGGACTTCACCCCGGGCAAG
CATGGCTTCATCGGACTCATCAACGCGCTCAGCGCATTTCCCAAGCCGCTGATCTGCGCGGTGAACGGCGTCGGCGTGGG
GATCGGTGCCACCATCCTGGGCTACGCCGATCTGGCGTTCATGTCGTCGACGGCCCGGCTGAAGTGCCCGTTCACCAGCC
TGGGGGTGGCCCCCGAGGCGGCCTCGTCCTACCTGCTGCCGCAACTGGTCGGCCGGCAGAACGCCGCCTGGCTGTTGATG
TCCTCGGAATGGGTCGACGCCGACGAGGCGCTGCGGATGGGCCTGGTCTGGCGGGTCTGCGCGCCCGACGAGCTGCTGCC
GCAGGCCCGTCATCACGCGGAAATCCTTGCCTCCCGCCCGATTTCGAGTTTGATGGCGGTCAAGCACACGATGATGGAAC
CGGTCCGGCCGCAGATCGCGGCGGCCACCGCGCGGGAGAACGCGCACTTCGCGGAGCTGATGGGCGCCCAGGCCAACGCG
GCCGCGCTGGCCGACTTCAACAAGCGCTGA

Upstream 100 bases:

>100_bases
ACTGGGACGAGTACGACCGGGTGATGGCCCGGGAGCGGCGGGCTGTCGTGCTGATCGCCCCGACCCGCGTCTACAGCAAC
GGCTGACCTAAGCTGCTGGC

Downstream 100 bases:

>100_bases
GCGGCAGGCACCAAGCAAACAGCACTAAGCGGCCCAGCTGAGGCGGGGGAGCGGCCTCAGACCGACGGGGCGGTCTCCAG
CTTCGCCGAAGCGGCCAGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVAVVLLTGAGRGFSAGTDLAEMQARITDPDFTPGK
HGFIGLINALSAFPKPLICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAASSYLLPQLVGRQNAAWLLM
SSEWVDADEALRMGLVWRVCAPDELLPQARHHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANA
AALADFNKR

Sequences:

>Translated_249_residues
MTLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVAVVLLTGAGRGFSAGTDLAEMQARITDPDFTPGK
HGFIGLINALSAFPKPLICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAASSYLLPQLVGRQNAAWLLM
SSEWVDADEALRMGLVWRVCAPDELLPQARHHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANA
AALADFNKR
>Mature_248_residues
TLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVAVVLLTGAGRGFSAGTDLAEMQARITDPDFTPGKH
GFIGLINALSAFPKPLICAVNGVGVGIGATILGYADLAFMSSTARLKCPFTSLGVAPEAASSYLLPQLVGRQNAAWLLMS
SEWVDADEALRMGLVWRVCAPDELLPQARHHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANAA
ALADFNKR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI45643119, Length=234, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI260275230, Length=234, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI260274832, Length=234, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI194097323, Length=188, Percent_Identity=32.9787234042553, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI221136756, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221136753, Length=230, Percent_Identity=26.9565217391304, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI221307494, Length=179, Percent_Identity=30.7262569832402, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI70995211, Length=193, Percent_Identity=28.4974093264249, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI4757966, Length=165, Percent_Identity=29.6969696969697, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI51538581, Length=165, Percent_Identity=29.6969696969697, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI25453481, Length=165, Percent_Identity=29.6969696969697, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI51538573, Length=165, Percent_Identity=29.6969696969697, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4757968, Length=165, Percent_Identity=29.6969696969697, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI49355787, Length=165, Percent_Identity=29.6969696969697, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI116235487, Length=163, Percent_Identity=29.4478527607362, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI157694516, Length=252, Percent_Identity=25, Blast_Score=64, Evalue=9e-11,
Organism=Escherichia coli, GI1787660, Length=207, Percent_Identity=37.1980676328502, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787659, Length=231, Percent_Identity=34.6320346320346, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI221142681, Length=210, Percent_Identity=32.8571428571429, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790281, Length=182, Percent_Identity=25.8241758241758, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17549921, Length=239, Percent_Identity=32.2175732217573, Blast_Score=110, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17535521, Length=209, Percent_Identity=30.1435406698565, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17554946, Length=205, Percent_Identity=29.7560975609756, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI25145438, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17536985, Length=185, Percent_Identity=28.6486486486486, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=200, Percent_Identity=27, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560910, Length=211, Percent_Identity=26.0663507109005, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=227, Percent_Identity=23.7885462555066, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24654903, Length=253, Percent_Identity=29.6442687747036, Blast_Score=118, Evalue=4e-27,
Organism=Drosophila melanogaster, GI20129971, Length=192, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24653477, Length=192, Percent_Identity=29.1666666666667, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24650670, Length=214, Percent_Identity=29.4392523364486, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920382, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19922422, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653139, Length=245, Percent_Identity=25.7142857142857, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 26495; Mature: 26364

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVAVVLLTGAGRGFSA
CEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
GTDLAEMQARITDPDFTPGKHGFIGLINALSAFPKPLICAVNGVGVGIGATILGYADLAF
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHH
MSSTARLKCPFTSLGVAPEAASSYLLPQLVGRQNAAWLLMSSEWVDADEALRMGLVWRVC
HCCCCEEECCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHEEEEC
APDELLPQARHHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANA
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCH
AALADFNKR
HHHHCCCCC
>Mature Secondary Structure 
TLQIDDDKRVRTLTLNRPEALNAFNEALYDATAEALLAAAEDPEVAVVLLTGAGRGFSA
EEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCC
GTDLAEMQARITDPDFTPGKHGFIGLINALSAFPKPLICAVNGVGVGIGATILGYADLAF
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHH
MSSTARLKCPFTSLGVAPEAASSYLLPQLVGRQNAAWLLMSSEWVDADEALRMGLVWRVC
HCCCCEEECCHHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHEEEEC
APDELLPQARHHAEILASRPISSLMAVKHTMMEPVRPQIAAATARENAHFAELMGAQANA
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHCCCCCH
AALADFNKR
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751302; 11481430 [H]