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The map label for this gene is oxyR

Identifier: 41407688

GI number: 41407688

Start: 1747674

End: 1748651

Strand: Direct

Name: oxyR

Synonym: MAP1590

Alternate gene names: 41407688

Gene position: 1747674-1748651 (Clockwise)

Preceding gene: 41407684

Following gene: 41407689

Centisome position: 36.19

GC content: 71.88

Gene sequence:

>978_bases
ATGTTGCCGCGTACCCTCAATGAAGTAAAGGTGATATTTCCCACTACACTTATAGGCATGTCCGATAAGACTTATCAGCC
CACCATCGCCGGTCTGCGCGCCTTCGTCGCGGTCGCCGAGAAGCGCCAATTCAGCGGTGCTGCAACGGCTTTGGGAGTCA
GCCAGTCGACGCTGTCGCAGGCGTTGGCGGCGCTGGAGGCAGGGCTGGGCACGCAGTTGGTGGAGCGCTCCACCCGGCGT
GTCTTCTTGACACCCCAGGGCGCCGAGCTGCTGCCGCACGCCCAGGCCGTGGTCGAGGCGGCCGACGCCTTCACCGCTGC
GGCGGCGGGTTCGGCGGACCCGTTGCGGGCCGGCATGCGGCTGGGGCTGATCCCCACGGTGGCGCCCTACGTGCTGCCGA
CCGTGCTGGCCGGAATCGCCGAACGGCGGCCCGGCCTGACCCTGCGGGTCACCGAGGACCAGACCGAACGGCTGCTGGCG
GTGCTGCGCGAGGGCGCGCTCGACGCGGCGCTGATCGCGCTGCCCGCCGAGACGGCGGGCGTCACCGCGATCCCGATCTA
CGACGAGGATTTCGTGCTCGCGCTTCCGCCGGGCCACCCGCTGGCGGGCAAGCGCCGGGTGCCGGCGACGGCGCTGGCCG
ACCTGCCGCTGCTGCTGGACGAGGGGCACTGCCTGCGCGACCAGGCGCTGGACGTCTGCCACAAGGCGGGTGTGCGGGCG
GAGCTGGCCAATACCCGGGCCGCGTCGCTGGCCACCGCGGTGCAGTGCGTGACCGGCGGCCTGGGGGTGACGCTCATCCC
GCAGAGCGCGGTCCCGGTCGAGGCGTCGCGCAGCCGGCTGGGCCTGGCCCAGTTCGCCGCGCCGCGCCCGGGCCGGCGCA
TCGGTCTGGTGTTCCGCTCGTCGAGCGGGCGCGACGACTCCTACCGCGAGCTGGCCGGGCTGATCAGCAGCCAGCACCAG
GTACGGCTGGTGAAGTAA

Upstream 100 bases:

>100_bases
CTCGTAGGCGGGGAACTGATCGCCGATGGTCAGCAGAGGCATGTCGCTCCTATCTGGATCTACTTAATCTGGATCAACTC
AAAATTAGCTTTCGTCCACC

Downstream 100 bases:

>100_bases
CCCTGCCGGCGGCCCGGCGCGGGTAGGTTTCGGCTCATGGAAAAAGTGATCGCCGTGCTTATGCGTGCCGATTCGGAGGA
GGACTGGTGCGCCCGCCAGC

Product: OxyR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLPRTLNEVKVIFPTTLIGMSDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGLGTQLVERSTRR
VFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLA
VLREGALDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATALADLPLLLDEGHCLRDQALDVCHKAGVRA
ELANTRAASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDSYRELAGLISSQHQ
VRLVK

Sequences:

>Translated_325_residues
MLPRTLNEVKVIFPTTLIGMSDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGLGTQLVERSTRR
VFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLA
VLREGALDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATALADLPLLLDEGHCLRDQALDVCHKAGVRA
ELANTRAASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDSYRELAGLISSQHQ
VRLVK
>Mature_325_residues
MLPRTLNEVKVIFPTTLIGMSDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGLGTQLVERSTRR
VFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLA
VLREGALDAALIALPAETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATALADLPLLLDEGHCLRDQALDVCHKAGVRA
ELANTRAASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDSYRELAGLISSQHQ
VRLVK

Specific function: Required for the induction the katG gene for catalase. Involved in the response to hydrogen peroxide [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=292, Percent_Identity=38.013698630137, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI157672245, Length=237, Percent_Identity=31.2236286919831, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693105, Length=280, Percent_Identity=27.5, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787879, Length=258, Percent_Identity=29.8449612403101, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788887, Length=244, Percent_Identity=30.7377049180328, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787601, Length=248, Percent_Identity=25.8064516129032, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787530, Length=246, Percent_Identity=28.4552845528455, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788748, Length=250, Percent_Identity=24.8, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367136, Length=254, Percent_Identity=27.1653543307087, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787806, Length=239, Percent_Identity=26.3598326359833, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081904, Length=272, Percent_Identity=26.8382352941176, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788481, Length=251, Percent_Identity=26.6932270916335, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693193, Length=160, Percent_Identity=30.625, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788297, Length=245, Percent_Identity=27.7551020408163, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789204, Length=174, Percent_Identity=28.735632183908, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790262, Length=258, Percent_Identity=25.968992248062, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34030; Mature: 34030

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRTLNEVKVIFPTTLIGMSDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQ
CCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHH
ALAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGMR
HHHHHHHCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCE
LGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLAVLREGALDAALIALPAETAG
ECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCC
VTAIPIYDEDFVLALPPGHPLAGKRRVPATALADLPLLLDEGHCLRDQALDVCHKAGVRA
EEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHCCCHH
ELANTRAASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRS
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCHHHHCCCCCCCEEEEEEEC
SSGRDDSYRELAGLISSQHQVRLVK
CCCCCHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MLPRTLNEVKVIFPTTLIGMSDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQ
CCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHH
ALAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGMR
HHHHHHHCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCE
LGLIPTVAPYVLPTVLAGIAERRPGLTLRVTEDQTERLLAVLREGALDAALIALPAETAG
ECCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCC
VTAIPIYDEDFVLALPPGHPLAGKRRVPATALADLPLLLDEGHCLRDQALDVCHKAGVRA
EEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHCCCCEECCCCCHHHHHHHHHHHCCCHH
ELANTRAASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRS
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCHHHHCCCCCCCEEEEEEEC
SSGRDDSYRELAGLISSQHQVRLVK
CCCCCHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7604044 [H]