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The map label for this gene is modB

Identifier: 41407665

GI number: 41407665

Start: 1721193

End: 1721969

Strand: Direct

Name: modB

Synonym: MAP1567

Alternate gene names: 41407665

Gene position: 1721193-1721969 (Clockwise)

Preceding gene: 41407664

Following gene: 41407666

Centisome position: 35.64

GC content: 72.33

Gene sequence:

>777_bases
CTGCCCCGCTGGGTGTACCTTCCCGCGGCGGCCGGGACCATGTTCGTGGTGCTGCCGTTGTTGGCGATCGCGGTCAAGGT
GGACTGGCCGCACTTCTGGTGGCTGATCACGAGCCCGTCGTCGCGCACGGCGCTGCTGCTGAGCCTGAGGACCGCCGCCG
CCAGCACCGCGCTGTGCGTGGCGCTGGGGGTGCCGATGGCGCTGGTGCTGGCGCGCGGCGGGACGCGGCTGGTCCGGTTG
CTGCGGCCCCTGATCCTGGTGCCGTTGGTGCTGCCGCCCGTGGTGGGCGGGATCGCGTTGTTGTATGCGTTCGGTCGGCT
CGGGCTGCTGGGGCACTACCTGGAAGCCGCGGGTATCAGCGTTGCGTTCAGCACCACCGCCGTGGTGCTGGCGCAGACCT
TCGTGTCGCTGCCGTTTCTGGTGATCTCGCTCGAGGGCGCGGCGCGCACCGCGGGCGCCGATTTCGAGGTGGTGGCCGCG
ACACTGGGCGCGCGACCCACCACGGTCTGGTGGCGCGTCACCCTGCCGCTGCTGTTGCCCGGTGTCGTGTCCGGGGCGGT
GCTGGCGTTCGCCCGCTCGCTGGGTGAGTTCGGCGCGACGCTGACCTTCGCCGGATCACGGCAGGGCGTCACCCGCACCC
TGCCGCTGGAGATCTACCTGCAGCGGGTGACCGACGCCGACGCGGCCGTGGCGCTGTCCATCCTGTTGGTGGTGGTGGCG
GCCGTGGTGGTGCTGGGGCTGGGCGCTCGCCGGCTGACCGGGACCGACGCCAGGTAG

Upstream 100 bases:

>100_bases
CATGCTGTGCAGCGAATAACCGGCGGCCCCACCTATTCGTCGGCGGGCCGAACGAGGCAGACGAGGCAAAGGGGTAGGCA
TTAGCAGACGCGGCACGGCG

Downstream 100 bases:

>100_bases
CCGCCGGCCATGAGCGAATTGCAGCTGCGCGCGGTCGTCTCGCAACGGCGCTTCGAGGTGGAGTTCTCGGTGGCCGCCGG
GGAGGTGCTGGCGGTGCTGG

Product: ModB

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPRWVYLPAAAGTMFVVLPLLAIAVKVDWPHFWWLITSPSSRTALLLSLRTAAASTALCVALGVPMALVLARGGTRLVRL
LRPLILVPLVLPPVVGGIALLYAFGRLGLLGHYLEAAGISVAFSTTAVVLAQTFVSLPFLVISLEGAARTAGADFEVVAA
TLGARPTTVWWRVTLPLLLPGVVSGAVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDADAAVALSILLVVVA
AVVVLGLGARRLTGTDAR

Sequences:

>Translated_258_residues
MPRWVYLPAAAGTMFVVLPLLAIAVKVDWPHFWWLITSPSSRTALLLSLRTAAASTALCVALGVPMALVLARGGTRLVRL
LRPLILVPLVLPPVVGGIALLYAFGRLGLLGHYLEAAGISVAFSTTAVVLAQTFVSLPFLVISLEGAARTAGADFEVVAA
TLGARPTTVWWRVTLPLLLPGVVSGAVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDADAAVALSILLVVVA
AVVVLGLGARRLTGTDAR
>Mature_257_residues
PRWVYLPAAAGTMFVVLPLLAIAVKVDWPHFWWLITSPSSRTALLLSLRTAAASTALCVALGVPMALVLARGGTRLVRLL
RPLILVPLVLPPVVGGIALLYAFGRLGLLGHYLEAAGISVAFSTTAVVLAQTFVSLPFLVISLEGAARTAGADFEVVAAT
LGARPTTVWWRVTLPLLLPGVVSGAVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDADAAVALSILLVVVAA
VVVLGLGARRLTGTDAR

Specific function: Part of the binding-protein-dependent transport system modABCD for molybdenum; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4149

COG function: function code P; ABC-type molybdate transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=213, Percent_Identity=31.924882629108, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1786980, Length=214, Percent_Identity=39.2523364485981, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI87082099, Length=226, Percent_Identity=29.646017699115, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787369, Length=217, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1787080, Length=236, Percent_Identity=25, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011867
- InterPro:   IPR006469 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26981; Mature: 26849

Theoretical pI: Translated: 11.65; Mature: 11.65

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRWVYLPAAAGTMFVVLPLLAIAVKVDWPHFWWLITSPSSRTALLLSLRTAAASTALCV
CCCEEEEECCHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCEEEEEEHHHHHHHHHHHH
ALGVPMALVLARGGTRLVRLLRPLILVPLVLPPVVGGIALLYAFGRLGLLGHYLEAAGIS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VAFSTTAVVLAQTFVSLPFLVISLEGAARTAGADFEVVAATLGARPTTVWWRVTLPLLLP
EEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHH
GVVSGAVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDADAAVALSILLVVVA
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHH
AVVVLGLGARRLTGTDAR
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PRWVYLPAAAGTMFVVLPLLAIAVKVDWPHFWWLITSPSSRTALLLSLRTAAASTALCV
CCEEEEECCHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCEEEEEEHHHHHHHHHHHH
ALGVPMALVLARGGTRLVRLLRPLILVPLVLPPVVGGIALLYAFGRLGLLGHYLEAAGIS
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VAFSTTAVVLAQTFVSLPFLVISLEGAARTAGADFEVVAATLGARPTTVWWRVTLPLLLP
EEHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEHHHHHH
GVVSGAVLAFARSLGEFGATLTFAGSRQGVTRTLPLEIYLQRVTDADAAVALSILLVVVA
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEECHHHHHHHHHCCCHHHHHHHHHHHHHH
AVVVLGLGARRLTGTDAR
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]