Click here to switch to the map view.

The map label for this gene is efp

Identifier: 41407195

GI number: 41407195

Start: 1149778

End: 1150341

Strand: Direct

Name: efp

Synonym: MAP1097

Alternate gene names: 41407195

Gene position: 1149778-1150341 (Clockwise)

Preceding gene: 41407194

Following gene: 41407196

Centisome position: 23.81

GC content: 66.31

Gene sequence:

>564_bases
GTGGCAAGCACTGCCGATTTCAAGAATGGACTGGTCCTGGTGATCGACGGCCAGCTGTGGCAGATCGTCGAGTTCCAGCA
CGTCAAACCCGGCAAGGGCCCGGCGTTCGTGCGGACCAAGCTGAAGAACGTGCTGTCCGGCAAGGTCGTCGACAAGACCT
ACAACGCGGGGGTGAAGGTGGAGACCGCCACCGTCGACCGCCGCGACACCACCTACCTGTACCGCGACGGCAGCGACTTC
GTCTTCATGGACAGCCAGGACTACGAGCAGCACCCGCTGCCCGAGTCGCTGGTGGGCGACGCGGCCCGGTTCCTGCTGGA
GGGCATGCCGGTGCAGGTGGCGTTCCACAACGGGTCGCCGCTGTACATCGAGTTGCCGGTGTCGGTCGAGATGGAGGTCA
CCCACACCGAGCCCGGCCTGCAGGGCGACCGGTCCAGCGCGGGCACCAAACCCGCCACCGTGGAAACCGGCGCGGAGATC
CAGGTGCCGCTGTTCATCAACACCGGCGACAAGCTCAAGGTGGACACCCGCGACGGCAGCTACCTGGGGCGCGTCAACGC
GTGA

Upstream 100 bases:

>100_bases
CGTCCTGGCCTGACGCCCGCCGGCGCCCTCTAAACTGGCCGACAAGTCCCACGACGGCCGCACCGCCGGCCGTCCATCCC
CGAGGAGATATAGGCGCACC

Downstream 100 bases:

>100_bases
GCAAACCCCTGAGGGGACGCCATCAGGCCCGCAAGCGCGCGGTCGACCTGCTGTTCGAGGCCGAGGCGCGGGGGTTGAGC
CCGGCCGAGGTGGTCGACGT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MASTADFKNGLVLVIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTYNAGVKVETATVDRRDTTYLYRDGSDF
VFMDSQDYEQHPLPESLVGDAARFLLEGMPVQVAFHNGSPLYIELPVSVEMEVTHTEPGLQGDRSSAGTKPATVETGAEI
QVPLFINTGDKLKVDTRDGSYLGRVNA

Sequences:

>Translated_187_residues
MASTADFKNGLVLVIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTYNAGVKVETATVDRRDTTYLYRDGSDF
VFMDSQDYEQHPLPESLVGDAARFLLEGMPVQVAFHNGSPLYIELPVSVEMEVTHTEPGLQGDRSSAGTKPATVETGAEI
QVPLFINTGDKLKVDTRDGSYLGRVNA
>Mature_186_residues
ASTADFKNGLVLVIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTYNAGVKVETATVDRRDTTYLYRDGSDFV
FMDSQDYEQHPLPESLVGDAARFLLEGMPVQVAFHNGSPLYIELPVSVEMEVTHTEPGLQGDRSSAGTKPATVETGAEIQ
VPLFINTGDKLKVDTRDGSYLGRVNA

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=42.2222222222222, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI87082061, Length=190, Percent_Identity=32.6315789473684, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_MYCA1 (A0QI55)

Other databases:

- EMBL:   CP000479
- RefSeq:   YP_882593.1
- ProteinModelPortal:   A0QI55
- SMR:   A0QI55
- STRING:   A0QI55
- EnsemblBacteria:   EBMYCT00000011282
- GeneID:   4526443
- GenomeReviews:   CP000479_GR
- KEGG:   mav:MAV_3411
- TIGR:   MAV_3411
- eggNOG:   COG0231
- GeneTree:   EBGT00050000016200
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   A0QI55
- ProtClustDB:   PRK00529
- BioCyc:   MAVI243243:MAV_3411-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20472; Mature: 20341

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTADFKNGLVLVIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTYNAGVKV
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCEEE
ETATVDRRDTTYLYRDGSDFVFMDSQDYEQHPLPESLVGDAARFLLEGMPVQVAFHNGSP
EEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCE
LYIELPVSVEMEVTHTEPGLQGDRSSAGTKPATVETGAEIQVPLFINTGDKLKVDTRDGS
EEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCC
YLGRVNA
EEEEECC
>Mature Secondary Structure 
ASTADFKNGLVLVIDGQLWQIVEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTYNAGVKV
CCCCCCCCCEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEEECCCCEEE
ETATVDRRDTTYLYRDGSDFVFMDSQDYEQHPLPESLVGDAARFLLEGMPVQVAFHNGSP
EEEEECCCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCE
LYIELPVSVEMEVTHTEPGLQGDRSSAGTKPATVETGAEIQVPLFINTGDKLKVDTRDGS
EEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEEEEEECCCEEEEECCCCC
YLGRVNA
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA