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The map label for this gene is bhbA [H]

Identifier: 41406771

GI number: 41406771

Start: 694342

End: 695934

Strand: Direct

Name: bhbA [H]

Synonym: MAP0673

Alternate gene names: 41406771

Gene position: 694342-695934 (Clockwise)

Preceding gene: 41406769

Following gene: 41406772

Centisome position: 14.38

GC content: 66.1

Gene sequence:

>1593_bases
TTGCAAGTACGTTATTCATCGATGGATAATACGGCCCACACTCCGTCTGGCATTCCGCTGCAGCCCGTCTACGGGCCGGC
GGACCGAAGCGCTGAGCCCCCGCAACCGGGCGAGTTCCCCTTCACCAGGGGTAACTTCGCCTCCGGCTATCGCGGCAAGC
TCTGGACCTTCCGCCAATATTCGGGATTCGGCACCGCCGAGGAGTCCAACCGCCGCTACCTGCTCGAGCAGGGCGGGACC
GGGCTGTCGGTGGCGCTGGACCTGCCGACCCAGTGCGGCTACGACTCCGACGATCCCGAGTTCGGCGAGGAGGTCGGCCG
GGTCGGCGTCGCGGTGGACACCCTGGCCGACTTCGAGATCTTGTTCGACGGCATTCCGCTGGACAAGCTCAGCACCAGCA
TGACGATCAACGGAACGGCGGCGATCCTGCTGGCTTTCTACGTCGCCGCGGCGGAAAAGAAGGGCATACCGCGGGCCAAG
CTCACCGGCACCATCCAGAACGACATCCTCAAGGAGTACGCCTCGCGCGGGACGTGGATCTGGCCGCCGGAGCCGTCGCT
GCGGCTGATCGCCGACACCATCGAGTTCTGCGCGGCCGAGGTGCCCAAGTTCAACGCGATCTCGGTGGCCGGCGCGCATT
TCCGCGATGCCGGCGCCAACGCGGTGCAGGAGATGGCGTTCACGCTGGCCGATGGAGTGACCTACTGCGACACGGTGGTG
GAGCGGGGCCGGATGACGATCGACCAGTTCGCCCCGCAGATCTCGTTCTTCTTCTACACCCACGGGGATTTCTTCGAGGA
GATCGCCAAATACCGTGCGGGACGGCGGCGTTGGGCGACGATCGTGCGGGAGCGGTACGGTGCGACGACGGCCAAGGCAT
CGATGTTCCGGTTCGGCTGCGTCTGCGGCGGCGCCTCCCTGTATGCGCCGCAGGCCCACAACAACATCGTCCGGGTGGCC
TACGAGGCGATGGCCGCGGTGCTCGGCGGCGTGCAGTCGATGTTCACCGCCGCTTGGGACGAGCCGTTCGCGCTGCCCAC
CGAGGAAACCACCACCCTGGCGCTGCGCACCCAGCAGATCCTGGCCTACGAAACCGGGGTGGCCAGTGTCGCCGACCCGC
TGGGCGGCTCCTACTTCGTCGAGGCGCTCACCGACGAGACCGAGGCCCGCATCATCGAGATCATGGCCGACCTCGACCGC
CATGGCGGCATGGTGTCCGCGATCGAGGACGGCTACCTGCAGGGGCTGATCGCCGACGAAGCGTTCCGGCTGCATCAAGA
CATCGAAGCCGGGACCCGTCCCGTCGTCGGCGTCAACCGGTTCGTGACCGAGGAGCCCGAACACGATGTGGTCACCTATG
AGCTCGACGCCGAAGGGCGCGACCTGCAACTCAAACGGCTGTCGAAGGTGAAGGCCGAAAGGGATTCGGCCGCAGTGAAA
TCCAGTCTCGCGGCGCTGTCGCGTGCCGCCGAAGGAGACGACAACCTGATGCACAAGCTCATCGACTGCGCCAACGCGTA
CTGCACGGTCGGGGAGATGGTCTCCGCGCTCAAGGCGGTGTGGGGCGAATTCCAGCAACCGGTGGTGTTCTAG

Upstream 100 bases:

>100_bases
CGTGCGGTCGGTGAGCGAGTTGTCAGCCATCTGTCTCCTTTGACCTGGTCAAGCCACCCGCTTGACCAGGTCAAACAAGC
GGTATTGGCATTCTCTTTTT

Downstream 100 bases:

>100_bases
TGGCCGTCCGGATTCTGGTTGCCAAACCCGGGTTGGACGGACACGACCGGGGCGCCAAGATCGTGGCCCGCACCTTGCGG
GACGCCGGATTCGAGGTCAT

Product: hypothetical protein

Products: NA

Alternate protein names: MCM [H]

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MQVRYSSMDNTAHTPSGIPLQPVYGPADRSAEPPQPGEFPFTRGNFASGYRGKLWTFRQYSGFGTAEESNRRYLLEQGGT
GLSVALDLPTQCGYDSDDPEFGEEVGRVGVAVDTLADFEILFDGIPLDKLSTSMTINGTAAILLAFYVAAAEKKGIPRAK
LTGTIQNDILKEYASRGTWIWPPEPSLRLIADTIEFCAAEVPKFNAISVAGAHFRDAGANAVQEMAFTLADGVTYCDTVV
ERGRMTIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATIVRERYGATTAKASMFRFGCVCGGASLYAPQAHNNIVRVA
YEAMAAVLGGVQSMFTAAWDEPFALPTEETTTLALRTQQILAYETGVASVADPLGGSYFVEALTDETEARIIEIMADLDR
HGGMVSAIEDGYLQGLIADEAFRLHQDIEAGTRPVVGVNRFVTEEPEHDVVTYELDAEGRDLQLKRLSKVKAERDSAAVK
SSLAALSRAAEGDDNLMHKLIDCANAYCTVGEMVSALKAVWGEFQQPVVF

Sequences:

>Translated_530_residues
MQVRYSSMDNTAHTPSGIPLQPVYGPADRSAEPPQPGEFPFTRGNFASGYRGKLWTFRQYSGFGTAEESNRRYLLEQGGT
GLSVALDLPTQCGYDSDDPEFGEEVGRVGVAVDTLADFEILFDGIPLDKLSTSMTINGTAAILLAFYVAAAEKKGIPRAK
LTGTIQNDILKEYASRGTWIWPPEPSLRLIADTIEFCAAEVPKFNAISVAGAHFRDAGANAVQEMAFTLADGVTYCDTVV
ERGRMTIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATIVRERYGATTAKASMFRFGCVCGGASLYAPQAHNNIVRVA
YEAMAAVLGGVQSMFTAAWDEPFALPTEETTTLALRTQQILAYETGVASVADPLGGSYFVEALTDETEARIIEIMADLDR
HGGMVSAIEDGYLQGLIADEAFRLHQDIEAGTRPVVGVNRFVTEEPEHDVVTYELDAEGRDLQLKRLSKVKAERDSAAVK
SSLAALSRAAEGDDNLMHKLIDCANAYCTVGEMVSALKAVWGEFQQPVVF
>Mature_530_residues
MQVRYSSMDNTAHTPSGIPLQPVYGPADRSAEPPQPGEFPFTRGNFASGYRGKLWTFRQYSGFGTAEESNRRYLLEQGGT
GLSVALDLPTQCGYDSDDPEFGEEVGRVGVAVDTLADFEILFDGIPLDKLSTSMTINGTAAILLAFYVAAAEKKGIPRAK
LTGTIQNDILKEYASRGTWIWPPEPSLRLIADTIEFCAAEVPKFNAISVAGAHFRDAGANAVQEMAFTLADGVTYCDTVV
ERGRMTIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATIVRERYGATTAKASMFRFGCVCGGASLYAPQAHNNIVRVA
YEAMAAVLGGVQSMFTAAWDEPFALPTEETTTLALRTQQILAYETGVASVADPLGGSYFVEALTDETEARIIEIMADLDR
HGGMVSAIEDGYLQGLIADEAFRLHQDIEAGTRPVVGVNRFVTEEPEHDVVTYELDAEGRDLQLKRLSKVKAERDSAAVK
SSLAALSRAAEGDDNLMHKLIDCANAYCTVGEMVSALKAVWGEFQQPVVF

Specific function: Catalyzes the interconversion of succinyl-CoA and methylmalonyl-CoA during the polyhydroxyalkanoate degradation pathway [H]

COG id: COG1884

COG function: function code I; Methylmalonyl-CoA mutase, N-terminal domain/subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=517, Percent_Identity=45.0676982591876, Blast_Score=458, Evalue=1e-129,
Organism=Escherichia coli, GI1789284, Length=531, Percent_Identity=43.1261770244821, Blast_Score=416, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI25144500, Length=517, Percent_Identity=44.6808510638298, Blast_Score=457, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: =5.4.99.2 [H]

Molecular weight: Translated: 57884; Mature: 57884

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVRYSSMDNTAHTPSGIPLQPVYGPADRSAEPPQPGEFPFTRGNFASGYRGKLWTFRQY
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
SGFGTAEESNRRYLLEQGGTGLSVALDLPTQCGYDSDDPEFGEEVGRVGVAVDTLADFEI
CCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
LFDGIPLDKLSTSMTINGTAAILLAFYVAAAEKKGIPRAKLTGTIQNDILKEYASRGTWI
HCCCCCHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEE
WPPEPSLRLIADTIEFCAAEVPKFNAISVAGAHFRDAGANAVQEMAFTLADGVTYCDTVV
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHCCCHHHHHHHHHHHHCCHHHHHHHH
ERGRMTIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATIVRERYGATTAKASMFRFGC
HCCCCCHHHHCCCEEEEEEECCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHH
VCGGASLYAPQAHNNIVRVAYEAMAAVLGGVQSMFTAAWDEPFALPTEETTTLALRTQQI
HCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHH
LAYETGVASVADPLGGSYFVEALTDETEARIIEIMADLDRHGGMVSAIEDGYLQGLIADE
HHHHCCHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
AFRLHQDIEAGTRPVVGVNRFVTEEPEHDVVTYELDAEGRDLQLKRLSKVKAERDSAAVK
HHHHHHHHHCCCCCEEECHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SSLAALSRAAEGDDNLMHKLIDCANAYCTVGEMVSALKAVWGEFQQPVVF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQVRYSSMDNTAHTPSGIPLQPVYGPADRSAEPPQPGEFPFTRGNFASGYRGKLWTFRQY
CCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
SGFGTAEESNRRYLLEQGGTGLSVALDLPTQCGYDSDDPEFGEEVGRVGVAVDTLADFEI
CCCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHH
LFDGIPLDKLSTSMTINGTAAILLAFYVAAAEKKGIPRAKLTGTIQNDILKEYASRGTWI
HCCCCCHHHHCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEE
WPPEPSLRLIADTIEFCAAEVPKFNAISVAGAHFRDAGANAVQEMAFTLADGVTYCDTVV
CCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHCCCHHHHHHHHHHHHCCHHHHHHHH
ERGRMTIDQFAPQISFFFYTHGDFFEEIAKYRAGRRRWATIVRERYGATTAKASMFRFGC
HCCCCCHHHHCCCEEEEEEECCHHHHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHH
VCGGASLYAPQAHNNIVRVAYEAMAAVLGGVQSMFTAAWDEPFALPTEETTTLALRTQQI
HCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHH
LAYETGVASVADPLGGSYFVEALTDETEARIIEIMADLDRHGGMVSAIEDGYLQGLIADE
HHHHCCHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHH
AFRLHQDIEAGTRPVVGVNRFVTEEPEHDVVTYELDAEGRDLQLKRLSKVKAERDSAAVK
HHHHHHHHHCCCCCEEECHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
SSLAALSRAAEGDDNLMHKLIDCANAYCTVGEMVSALKAVWGEFQQPVVF
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9889346; 11481431 [H]