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The map label for this gene is degP [H]

Identifier: 41406501

GI number: 41406501

Start: 425977

End: 427170

Strand: Direct

Name: degP [H]

Synonym: MAP0403

Alternate gene names: 41406501

Gene position: 425977-427170 (Clockwise)

Preceding gene: 41406500

Following gene: 41406504

Centisome position: 8.82

GC content: 70.27

Gene sequence:

>1194_bases
ATGACCCCGTCGCAGTGGCTGGACGTCGCGGTGCTGGCGGTGGCCTTCATCGCGGCGATCTCGGGCTGGCGGTCCGGCGC
GTTGGGGTCGCTGCTGTCGTTCGTGGGCGTGCTGCTCGGCGCGATCGCCGGGGTGCTGCTGGCGCCCCACCTCGTCAGCC
ACATCGCCGCGCCGCGCGCGAAACTGTTTGCGGCACTGTTCTTGATCCTGGCGCTGGTGGTCATCGGCGAGGTCGCCGGC
GTGGTGTTGGGGCGCGCGGTGCGGGGCGCGATCCGCAGCCGGTCCATCCGCACCGTCGACTCGGTGATCGGGGTCGGCGT
GCAGCTGGTGGTGGTGTTGACCGCGGCGTGGCTGCTGGCGACGCCGCTGACCCAGTCCAAGGATCAGCCCGAGCTGGCCG
CCGCGGTGCGCGGTTCCCGAGTGTTGGCCAAGGTCAACGAGGTTGCCCCGCCGTGGCTCAAGACGGTGCCCAAGCGGCTC
TCGGCGCTGCTGAACACTTCCGGGCTGCCCGCGGTGCTCGAGCCGTTCAGCCGCACCCCGGTGATCCCGGTCGCCTCACC
CGATCCCGAGCTGGCCAGCAACCCGGTGGTGCAGGCCACCGCGCCCAGCGTCGTCAAGGTGCGCAGCCTGGCGCCCAGCT
GCCAAAAGGTTTTGGAGGGCAGCGGATTCGTGATCGCGCCCGACCGGGTGATGACCAACGCGCACGTGGTGGCCGGTTCC
AACAGCGTGCAGATCTACGCCAGCGGCAACCCGCTGGACGCCACCGTGGTGTCCTACGACCCGTCCGTCGACATCGCGAT
CCTCGCCGTCCCCAACCTGCCGCCGCCGCCGTTGCCGTTCGCCCAGACCGAGGCGAAAACCGGGGCCAGCGTGGTGGTGC
TGGGTTATCCCGGCGGCGGCAACTTCACCGCGACGCCGGCCCGGATCCGCGAGCTGATCAAGTTGAGCGGACCCGACATC
TACCGCGACCCGGCGCCGGTCACCCGCGACGTGTACACCATCAGAGCCAGTGTGGAGCAAGGCAATTCGGGTGGACCGCT
GATCGACCTGAACGGCCAGGTGCTCGGCGTGGTGTTCGGCGCGGCCGTCGACGACCCCGACACCGGCTTCGTGTTGACCG
CCGACGAGGTGGCCGGTCAGCTCGCCAAGATCGGCGAGACCAAGACGGTGGGCACCGGGTCCTGCGTCAGTTGA

Upstream 100 bases:

>100_bases
GCTGGGCCCAGCCCTGGGACACCTCCGATCAGCGGGAGTTGGACGCGGCGATGGCGCTGGTCGGCGAGCGGGGTGACGCA
CTCGAATGAACCTGAATTCG

Downstream 100 bases:

>100_bases
CGGCCGGGCCGTACACGTCCTCGAGGAAGCTCGTCAGGTGCCGGTTGACCTCCTCCGGCGCCTCTTCGTGGCTGAAATGC
CCTGCGCCCGCGACGGTTAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MTPSQWLDVAVLAVAFIAAISGWRSGALGSLLSFVGVLLGAIAGVLLAPHLVSHIAAPRAKLFAALFLILALVVIGEVAG
VVLGRAVRGAIRSRSIRTVDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPELAAAVRGSRVLAKVNEVAPPWLKTVPKRL
SALLNTSGLPAVLEPFSRTPVIPVASPDPELASNPVVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGS
NSVQIYASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFAQTEAKTGASVVVLGYPGGGNFTATPARIRELIKLSGPDI
YRDPAPVTRDVYTIRASVEQGNSGGPLIDLNGQVLGVVFGAAVDDPDTGFVLTADEVAGQLAKIGETKTVGTGSCVS

Sequences:

>Translated_397_residues
MTPSQWLDVAVLAVAFIAAISGWRSGALGSLLSFVGVLLGAIAGVLLAPHLVSHIAAPRAKLFAALFLILALVVIGEVAG
VVLGRAVRGAIRSRSIRTVDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPELAAAVRGSRVLAKVNEVAPPWLKTVPKRL
SALLNTSGLPAVLEPFSRTPVIPVASPDPELASNPVVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGS
NSVQIYASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFAQTEAKTGASVVVLGYPGGGNFTATPARIRELIKLSGPDI
YRDPAPVTRDVYTIRASVEQGNSGGPLIDLNGQVLGVVFGAAVDDPDTGFVLTADEVAGQLAKIGETKTVGTGSCVS
>Mature_396_residues
TPSQWLDVAVLAVAFIAAISGWRSGALGSLLSFVGVLLGAIAGVLLAPHLVSHIAAPRAKLFAALFLILALVVIGEVAGV
VLGRAVRGAIRSRSIRTVDSVIGVGVQLVVVLTAAWLLATPLTQSKDQPELAAAVRGSRVLAKVNEVAPPWLKTVPKRLS
ALLNTSGLPAVLEPFSRTPVIPVASPDPELASNPVVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGSN
SVQIYASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFAQTEAKTGASVVVLGYPGGGNFTATPARIRELIKLSGPDIY
RDPAPVTRDVYTIRASVEQGNSGGPLIDLNGQVLGVVFGAAVDDPDTGFVLTADEVAGQLAKIGETKTVGTGSCVS

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=209, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 40679; Mature: 40547

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSQWLDVAVLAVAFIAAISGWRSGALGSLLSFVGVLLGAIAGVLLAPHLVSHIAAPRA
CCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KLFAALFLILALVVIGEVAGVVLGRAVRGAIRSRSIRTVDSVIGVGVQLVVVLTAAWLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TPLTQSKDQPELAAAVRGSRVLAKVNEVAPPWLKTVPKRLSALLNTSGLPAVLEPFSRTP
CCCCCCCCCCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCC
VIPVASPDPELASNPVVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGS
EEECCCCCCCCCCCCEEECCCCCHHHHHHCCHHHHHHHCCCCEEEECCHHCCCCEEEECC
NSVQIYASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFAQTEAKTGASVVVLGYPGGG
CEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCC
NFTATPARIRELIKLSGPDIYRDPAPVTRDVYTIRASVEQGNSGGPLIDLNGQVLGVVFG
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCCEEEECCCEEEEEEE
AAVDDPDTGFVLTADEVAGQLAKIGETKTVGTGSCVS
CCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPSQWLDVAVLAVAFIAAISGWRSGALGSLLSFVGVLLGAIAGVLLAPHLVSHIAAPRA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
KLFAALFLILALVVIGEVAGVVLGRAVRGAIRSRSIRTVDSVIGVGVQLVVVLTAAWLLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
TPLTQSKDQPELAAAVRGSRVLAKVNEVAPPWLKTVPKRLSALLNTSGLPAVLEPFSRTP
CCCCCCCCCCHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCC
VIPVASPDPELASNPVVQATAPSVVKVRSLAPSCQKVLEGSGFVIAPDRVMTNAHVVAGS
EEECCCCCCCCCCCCEEECCCCCHHHHHHCCHHHHHHHCCCCEEEECCHHCCCCEEEECC
NSVQIYASGNPLDATVVSYDPSVDIAILAVPNLPPPPLPFAQTEAKTGASVVVLGYPGGG
CEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEECCCC
NFTATPARIRELIKLSGPDIYRDPAPVTRDVYTIRASVEQGNSGGPLIDLNGQVLGVVFG
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEHHCCCCCCCEEEECCCEEEEEEE
AAVDDPDTGFVLTADEVAGQLAKIGETKTVGTGSCVS
CCCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]